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The map label for this gene is pkn2 [H]

Identifier: 15899909

GI number: 15899909

Start: 2953037

End: 2955046

Strand: Reverse

Name: pkn2 [H]

Synonym: SSO3207

Alternate gene names: 15899909

Gene position: 2955046-2953037 (Counterclockwise)

Preceding gene: 15899910

Following gene: 15899906

Centisome position: 98.76

GC content: 34.68

Gene sequence:

>2010_bases
GTGAAGTTAGTATTACAGTTAGATGATCAGAAATATTTATACGTTGATGGCGTAATTAGGCCTTTTGACGGTAAGATAAA
GACTAAAGATGATGTGATAGGATATGGTGTTATTTATGACGCAGGTAAGGTTAAAGTTTTATATGATTATAAGGTAGTGA
GAGTAAACGATAGCAATGTAATTACGCAAGCAGTATTGAAGGAGAAAGTAGATAAGTTGAATATGTATTTATTTGAATAT
GGTAATACAATATATGTATATTTTGGAAATATTTCTAATCCTAAATTAAACTTTCCATATATGATTATATATGGTATACC
TATTGCTTTAGGTTCTAAAGTCGAGATAATCGAGGCTATAAATAGAGACTACAAGGTAGCGTTATACGCATTAAATAGTT
TTAGGAATGATTCTAGTATAGTTAATCATTCCATTTTATCTTTAGTTAAATTTGAGAAATGTGATGATGCAGTAAGATAT
TATAAAGAACTGAGAGTTTCCGACCCAGAGGTTTCCTTAGCAGTAGCTCAATGCATGGAGAGAATAGGAGACGAGTTGGA
AGCCTTAAAGATTTACTCATTTTTATCTGAGGAGAAGTATAGGGAATTGGAAAGTAAGATAAGAAGCAAGGTAAACGCAA
TTATTGAGGAGTATAGGAAAGAGGGGAATGTGAAACTCTTAATAGACTCAGTTAAGATGCTACCAACGTATGATGCACCG
CTTATTGAATTAGGGTGGCATTATGTTAACAAAAGAAAATTTGAGGAAGCGGTAAAATACTTTGAAGAAGCTGTTAAAAG
AGTACCAACATTCCATAACCTCTTGTTATATGCGTGGTCTTTGATAGGTAATGAGAGATATAGGGAAGCGTTAGAGGTTA
TTGAGAAGGCAGAGAAAATTAAGCGTAACGCTGGTTCTGCATACATAAAAGGTTTAGCTTTAGAAGGTTTGAATGCTCCA
TCTCAAGCTGAAAGGGAGTTTCTTTACGCGTGTAGGGAAGGTATAATTGACGCGTGCATGAAGACTAGATCATACAAACT
ATACATACCAGAACCATTTGATGCAACTGCTTGGTTAAGTTATGTACTCTATGGATATGAGGTAAAGCAATTGTTGGGAA
ATGGCGGTATGGGTTATGTACTATTAGTTGAGAGGAATGGTAAGAAATACGCTATGAAAGTGATGAAGAAGGAGTATACT
TTTATAGAGATGCTTTATGAAGTTGCAAAAATGCAAGAAATCTCTAAGAGGTCTGAATACTTAGTTAAAATATTCGCTAG
TTTTCTAGATGAGAACTGGACAGATTACTTCAGTTCTCCACCCGCAATAATAATGGAATATATGGAAGGAGGTGACTTAA
GGTCAATCCTAGTGGATCAAGAGTATTCTGCTTTGCGTCATTCCGTTAAATGGCCTCAAGTGGTAGCTTTAATATTTTCT
AAAATTGCCAAGGCCGTTATAGAAGTTCATAAAGAGGGATATACACATTGTGACATAAAACCATCTAATATTTTGTTCAA
TAAGAAACTGCCAAGATACGGTGAAGATGCTCTAAATTCTTTGCTCAATTTTGAAGTTGTACCTAAATTATCTGATTTGG
GTTCTTCGGTAAAAATAGGTACTCCGGTAATGCACTATACTCCCTACTATGCTCATCCCTTACAAAGATTTGGTAATAGA
GCCGAAACCATGTTTGACGTTTACTCTTTTTCAGTATCCCTTTACGTATCTCTTACTAATAATTTTCCATTTCCCGAATG
GCTAGAAAACGAAATCGAAGAAGCGGTAAAGAATCCAGAAAAGAGAAAACAAGCCTTGGATGATTTTCACAACGCAACGC
CTAGACTTGATTATGTACCTGCGGAATTCAAAGATCTTATAACGATGGGGTTGAAGGGTGAAATTAGCATGTTAGAAATA
AATAAGAGATTGGAAGAAATTTTGGTCGAAGATTATAATATAGACATTAATAATCTGAACAGTGAAGCAGAAAAGCTTAT
AAACTATTGA

Upstream 100 bases:

>100_bases
AAGATGTGGTGTCTATAATTTGGCTATAATATGGCTCTTAGTGAAGACGAGGTATTATGTGATTTAAGTTACTTAAGATA
TTCCTTAGAACAGAGTTAGT

Downstream 100 bases:

>100_bases
TGACAGTTATATAAAATAAAAGGATCGGTGAAAAAGAATGATAGAGCCAATGGCTAAGAAAGTGTTCGAAGGACTAGCGT
ATACGATATGGGAAGACGAT

Product: Ser/thr protein kinase, putative

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 669; Mature: 669

Protein sequence:

>669_residues
MKLVLQLDDQKYLYVDGVIRPFDGKIKTKDDVIGYGVIYDAGKVKVLYDYKVVRVNDSNVITQAVLKEKVDKLNMYLFEY
GNTIYVYFGNISNPKLNFPYMIIYGIPIALGSKVEIIEAINRDYKVALYALNSFRNDSSIVNHSILSLVKFEKCDDAVRY
YKELRVSDPEVSLAVAQCMERIGDELEALKIYSFLSEEKYRELESKIRSKVNAIIEEYRKEGNVKLLIDSVKMLPTYDAP
LIELGWHYVNKRKFEEAVKYFEEAVKRVPTFHNLLLYAWSLIGNERYREALEVIEKAEKIKRNAGSAYIKGLALEGLNAP
SQAEREFLYACREGIIDACMKTRSYKLYIPEPFDATAWLSYVLYGYEVKQLLGNGGMGYVLLVERNGKKYAMKVMKKEYT
FIEMLYEVAKMQEISKRSEYLVKIFASFLDENWTDYFSSPPAIIMEYMEGGDLRSILVDQEYSALRHSVKWPQVVALIFS
KIAKAVIEVHKEGYTHCDIKPSNILFNKKLPRYGEDALNSLLNFEVVPKLSDLGSSVKIGTPVMHYTPYYAHPLQRFGNR
AETMFDVYSFSVSLYVSLTNNFPFPEWLENEIEEAVKNPEKRKQALDDFHNATPRLDYVPAEFKDLITMGLKGEISMLEI
NKRLEEILVEDYNIDINNLNSEAEKLINY

Sequences:

>Translated_669_residues
MKLVLQLDDQKYLYVDGVIRPFDGKIKTKDDVIGYGVIYDAGKVKVLYDYKVVRVNDSNVITQAVLKEKVDKLNMYLFEY
GNTIYVYFGNISNPKLNFPYMIIYGIPIALGSKVEIIEAINRDYKVALYALNSFRNDSSIVNHSILSLVKFEKCDDAVRY
YKELRVSDPEVSLAVAQCMERIGDELEALKIYSFLSEEKYRELESKIRSKVNAIIEEYRKEGNVKLLIDSVKMLPTYDAP
LIELGWHYVNKRKFEEAVKYFEEAVKRVPTFHNLLLYAWSLIGNERYREALEVIEKAEKIKRNAGSAYIKGLALEGLNAP
SQAEREFLYACREGIIDACMKTRSYKLYIPEPFDATAWLSYVLYGYEVKQLLGNGGMGYVLLVERNGKKYAMKVMKKEYT
FIEMLYEVAKMQEISKRSEYLVKIFASFLDENWTDYFSSPPAIIMEYMEGGDLRSILVDQEYSALRHSVKWPQVVALIFS
KIAKAVIEVHKEGYTHCDIKPSNILFNKKLPRYGEDALNSLLNFEVVPKLSDLGSSVKIGTPVMHYTPYYAHPLQRFGNR
AETMFDVYSFSVSLYVSLTNNFPFPEWLENEIEEAVKNPEKRKQALDDFHNATPRLDYVPAEFKDLITMGLKGEISMLEI
NKRLEEILVEDYNIDINNLNSEAEKLINY
>Mature_669_residues
MKLVLQLDDQKYLYVDGVIRPFDGKIKTKDDVIGYGVIYDAGKVKVLYDYKVVRVNDSNVITQAVLKEKVDKLNMYLFEY
GNTIYVYFGNISNPKLNFPYMIIYGIPIALGSKVEIIEAINRDYKVALYALNSFRNDSSIVNHSILSLVKFEKCDDAVRY
YKELRVSDPEVSLAVAQCMERIGDELEALKIYSFLSEEKYRELESKIRSKVNAIIEEYRKEGNVKLLIDSVKMLPTYDAP
LIELGWHYVNKRKFEEAVKYFEEAVKRVPTFHNLLLYAWSLIGNERYREALEVIEKAEKIKRNAGSAYIKGLALEGLNAP
SQAEREFLYACREGIIDACMKTRSYKLYIPEPFDATAWLSYVLYGYEVKQLLGNGGMGYVLLVERNGKKYAMKVMKKEYT
FIEMLYEVAKMQEISKRSEYLVKIFASFLDENWTDYFSSPPAIIMEYMEGGDLRSILVDQEYSALRHSVKWPQVVALIFS
KIAKAVIEVHKEGYTHCDIKPSNILFNKKLPRYGEDALNSLLNFEVVPKLSDLGSSVKIGTPVMHYTPYYAHPLQRFGNR
AETMFDVYSFSVSLYVSLTNNFPFPEWLENEIEEAVKNPEKRKQALDDFHNATPRLDYVPAEFKDLITMGLKGEISMLEI
NKRLEEILVEDYNIDINNLNSEAEKLINY

Specific function: Regulates the activity of endogenous beta-lactamase or related enzymes, by blocking their secretion by phosphorylation, in response to an external signal yet to be identified [H]

COG id: COG0457

COG function: function code R; FOG: TPR repeat

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6325053, Length=240, Percent_Identity=25.8333333333333, Blast_Score=64, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24663340, Length=230, Percent_Identity=29.1304347826087, Blast_Score=66, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017441
- InterPro:   IPR017442
- InterPro:   IPR008271
- InterPro:   IPR002290 [H]

Pfam domain/function: PF00211 Guanylate_cyc; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 77370; Mature: 77370

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: PS50005 TPR ; PS50293 TPR_REGION ; PS00107 PROTEIN_KINASE_ATP ; PS00108 PROTEIN_KINASE_ST ; PS50011 PROTEIN_KINASE_DOM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLVLQLDDQKYLYVDGVIRPFDGKIKTKDDVIGYGVIYDAGKVKVLYDYKVVRVNDSNV
CEEEEEECCCEEEEECCEEECCCCCCCCCCCEEEEEEEECCCCEEEEEEEEEEEECCCHH
ITQAVLKEKVDKLNMYLFEYGNTIYVYFGNISNPKLNFPYMIIYGIPIALGSKVEIIEAI
HHHHHHHHHHHHHHHHEEEECCEEEEEECCCCCCCCCCCEEEEEECCHHCCCCHHHHHHH
NRDYKVALYALNSFRNDSSIVNHSILSLVKFEKCDDAVRYYKELRVSDPEVSLAVAQCME
CCCCEEEEEEEHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
RIGDELEALKIYSFLSEEKYRELESKIRSKVNAIIEEYRKEGNVKLLIDSVKMLPTYDAP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECHHHCCCCCCC
LIELGWHYVNKRKFEEAVKYFEEAVKRVPTFHNLLLYAWSLIGNERYREALEVIEKAEKI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
KRNAGSAYIKGLALEGLNAPSQAEREFLYACREGIIDACMKTRSYKLYIPEPFDATAWLS
HHCCCCHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHH
YVLYGYEVKQLLGNGGMGYVLLVERNGKKYAMKVMKKEYTFIEMLYEVAKMQEISKRSEY
HHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVKIFASFLDENWTDYFSSPPAIIMEYMEGGDLRSILVDQEYSALRHSVKWPQVVALIFS
HHHHHHHHHCCCCHHHHCCCHHHHHHHHCCCCCHHHEECCHHHHHHHCCCHHHHHHHHHH
KIAKAVIEVHKEGYTHCDIKPSNILFNKKLPRYGEDALNSLLNFEVVPKLSDLGSSVKIG
HHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHCCEECCCHHHCCCCEECC
TPVMHYTPYYAHPLQRFGNRAETMFDVYSFSVSLYVSLTNNFPFPEWLENEIEEAVKNPE
CCCEECCCHHHHHHHHHCCHHHHHHHHHEEEEEEEEEEECCCCCHHHHHHHHHHHHCCHH
KRKQALDDFHNATPRLDYVPAEFKDLITMGLKGEISMLEINKRLEEILVEDYNIDINNLN
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCC
SEAEKLINY
HHHHHHCCC
>Mature Secondary Structure
MKLVLQLDDQKYLYVDGVIRPFDGKIKTKDDVIGYGVIYDAGKVKVLYDYKVVRVNDSNV
CEEEEEECCCEEEEECCEEECCCCCCCCCCCEEEEEEEECCCCEEEEEEEEEEEECCCHH
ITQAVLKEKVDKLNMYLFEYGNTIYVYFGNISNPKLNFPYMIIYGIPIALGSKVEIIEAI
HHHHHHHHHHHHHHHHEEEECCEEEEEECCCCCCCCCCCEEEEEECCHHCCCCHHHHHHH
NRDYKVALYALNSFRNDSSIVNHSILSLVKFEKCDDAVRYYKELRVSDPEVSLAVAQCME
CCCCEEEEEEEHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
RIGDELEALKIYSFLSEEKYRELESKIRSKVNAIIEEYRKEGNVKLLIDSVKMLPTYDAP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECHHHCCCCCCC
LIELGWHYVNKRKFEEAVKYFEEAVKRVPTFHNLLLYAWSLIGNERYREALEVIEKAEKI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
KRNAGSAYIKGLALEGLNAPSQAEREFLYACREGIIDACMKTRSYKLYIPEPFDATAWLS
HHCCCCHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHH
YVLYGYEVKQLLGNGGMGYVLLVERNGKKYAMKVMKKEYTFIEMLYEVAKMQEISKRSEY
HHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVKIFASFLDENWTDYFSSPPAIIMEYMEGGDLRSILVDQEYSALRHSVKWPQVVALIFS
HHHHHHHHHCCCCHHHHCCCHHHHHHHHCCCCCHHHEECCHHHHHHHCCCHHHHHHHHHH
KIAKAVIEVHKEGYTHCDIKPSNILFNKKLPRYGEDALNSLLNFEVVPKLSDLGSSVKIG
HHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHCCEECCCHHHCCCCEECC
TPVMHYTPYYAHPLQRFGNRAETMFDVYSFSVSLYVSLTNNFPFPEWLENEIEEAVKNPE
CCCEECCCHHHHHHHHHCCHHHHHHHHHEEEEEEEEEEECCCCCHHHHHHHHHHHHCCHH
KRKQALDDFHNATPRLDYVPAEFKDLITMGLKGEISMLEINKRLEEILVEDYNIDINNLN
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCC
SEAEKLINY
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7774814 [H]