BacMap

Definition	Sulfolobus solfataricus P2 chromosome, complete genome.
Accession	NC_002754
Length	2,992,245

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The map label for this gene is yeaE [H]

Identifier: 15899910

GI number: 15899910

Start: 2955190

End: 2955987

Strand: Reverse

Name: yeaE [H]

Synonym: SSO3209

Alternate gene names: 15899910

Gene position: 2955987-2955190 (Counterclockwise)

Preceding gene: 15899911

Following gene: 15899909

Centisome position: 98.79

GC content: 33.46

Gene sequence:

>798_bases
ATGAGGTTATGTAATAAGGACGTCTCACAAATTGGTTTTGGGACTTGGAAAATTGGAGGAGGGTATTGGAATCCAGATTA
TTCTAAGGATTCCCATTATATAGAAATATTAAAGTATGTGATAAGTAAGGGAATAAACGTTATCGATACTGCGGAAATGT
ATGGTGGAGGACATTCTGAAGAACTTGTTGGAAAAGCTATAGAGAATTTTGATAGGGATAAAATTTTCATTATAACTAAG
GTATGGTCTAATCATCTGAAGTACGATGATTTAATTAGGTCTGCTAAAAATAGTCTAAAAAGGCTTAACGCGAAGTATAT
TGACCTATACTTAATCCATTGGCCGAATTCCTCTGTACCACTAGAGGAAAGTTTAAGAGCAATGGAGGAGTTGGTAGATC
AAGGCATTGTAAATTGTATTGGAGTAAGCAATTTTGATATTAAACTTTTAGAAGAAACAATGTCGATAACTAAGAAATAT
GAAATAACTGCAAATGAAATAGAGTATAATGTTGAAAATAAAAGTGCGGAAAAGGATGTTATACCGTTCTGCGAAAGGAA
TAATATAAAAGTCATAGCGTATTCTCCTCTCGCTAGGGGAAATGCTAAAAACAATAAAATACTAGAGGAGATTGGACGAA
AATACAATAAGACCTCTGTTCAAGTAGCCTTAAATTACCTTTTGAGAAGATCAATCCCAATACCTAAGGCTTCTAGTAAA
GATCATATTGATGAGATACTTGGAGCTTTAGGATGGAATCTAAGTGATGAGGATTATGAGAGGATTTCGAAAATTTAA

Upstream 100 bases:

>100_bases
CTTGGGAGATTAAGCCTGCCTTAATAAGGGGCTTAGAGAAAATGAGAAGAGAGAATAAAATAGCTGTGATTCAAGTTATA
GTAGACAAGGTGAGATAATC

Downstream 100 bases:

>100_bases
ATAGCTCAGAAAACTCTGAAGAAAGACGTTTTAAAAGGTATAAAAGATGTGGTGTCTATAATTTGGCTATAATATGGCTC
TTAGTGAAGACGAGGTATTA

Product: aldo/keto reductase family oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MRLCNKDVSQIGFGTWKIGGGYWNPDYSKDSHYIEILKYVISKGINVIDTAEMYGGGHSEELVGKAIENFDRDKIFIITK
VWSNHLKYDDLIRSAKNSLKRLNAKYIDLYLIHWPNSSVPLEESLRAMEELVDQGIVNCIGVSNFDIKLLEETMSITKKY
EITANEIEYNVENKSAEKDVIPFCERNNIKVIAYSPLARGNAKNNKILEEIGRKYNKTSVQVALNYLLRRSIPIPKASSK
DHIDEILGALGWNLSDEDYERISKI

Sequences:

>Translated_265_residues
MRLCNKDVSQIGFGTWKIGGGYWNPDYSKDSHYIEILKYVISKGINVIDTAEMYGGGHSEELVGKAIENFDRDKIFIITK
VWSNHLKYDDLIRSAKNSLKRLNAKYIDLYLIHWPNSSVPLEESLRAMEELVDQGIVNCIGVSNFDIKLLEETMSITKKY
EITANEIEYNVENKSAEKDVIPFCERNNIKVIAYSPLARGNAKNNKILEEIGRKYNKTSVQVALNYLLRRSIPIPKASSK
DHIDEILGALGWNLSDEDYERISKI
>Mature_265_residues
MRLCNKDVSQIGFGTWKIGGGYWNPDYSKDSHYIEILKYVISKGINVIDTAEMYGGGHSEELVGKAIENFDRDKIFIITK
VWSNHLKYDDLIRSAKNSLKRLNAKYIDLYLIHWPNSSVPLEESLRAMEELVDQGIVNCIGVSNFDIKLLEETMSITKKY
EITANEIEYNVENKSAEKDVIPFCERNNIKVIAYSPLARGNAKNNKILEEIGRKYNKTSVQVALNYLLRRSIPIPKASSK
DHIDEILGALGWNLSDEDYERISKI

Specific function: Unknown

COG id: COG0656

COG function: function code R; Aldo/keto reductases, related to diketogulonate reductase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI223468663, Length=289, Percent_Identity=29.0657439446367, Blast_Score=107, Evalue=8e-24,
Organism=Homo sapiens, GI310109922, Length=265, Percent_Identity=30.5660377358491, Blast_Score=105, Evalue=5e-23,
Organism=Homo sapiens, GI291291012, Length=265, Percent_Identity=29.811320754717, Blast_Score=104, Evalue=9e-23,
Organism=Homo sapiens, GI45446745, Length=284, Percent_Identity=29.5774647887324, Blast_Score=102, Evalue=3e-22,
Organism=Homo sapiens, GI4503285, Length=284, Percent_Identity=29.5774647887324, Blast_Score=102, Evalue=3e-22,
Organism=Homo sapiens, GI310109920, Length=284, Percent_Identity=29.5774647887324, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI93277124, Length=307, Percent_Identity=27.0358306188925, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI24497577, Length=292, Percent_Identity=24.6575342465753, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI5174391, Length=292, Percent_Identity=24.6575342465753, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI24497583, Length=285, Percent_Identity=29.4736842105263, Blast_Score=101, Evalue=9e-22,
Organism=Homo sapiens, GI5453543, Length=284, Percent_Identity=28.5211267605634, Blast_Score=96, Evalue=2e-20,
Organism=Homo sapiens, GI24497585, Length=280, Percent_Identity=27.8571428571429, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI4502049, Length=287, Percent_Identity=30.6620209059233, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI5174695, Length=297, Percent_Identity=26.5993265993266, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI27436969, Length=206, Percent_Identity=27.1844660194175, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI4504825, Length=206, Percent_Identity=27.1844660194175, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI300116273, Length=277, Percent_Identity=27.4368231046931, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI27436964, Length=206, Percent_Identity=26.2135922330097, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI27436966, Length=206, Percent_Identity=26.2135922330097, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI27436962, Length=206, Percent_Identity=26.2135922330097, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI223718702, Length=173, Percent_Identity=29.4797687861272, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI41152114, Length=206, Percent_Identity=28.1553398058252, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI27436971, Length=206, Percent_Identity=24.2718446601942, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI41327764, Length=168, Percent_Identity=29.1666666666667, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI1788081, Length=267, Percent_Identity=33.3333333333333, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1786400, Length=265, Percent_Identity=30.9433962264151, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1788070, Length=305, Percent_Identity=29.1803278688525, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI87081735, Length=299, Percent_Identity=27.7591973244147, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI87082198, Length=264, Percent_Identity=28.4090909090909, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI1787674, Length=276, Percent_Identity=26.8115942028986, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI1789199, Length=235, Percent_Identity=27.6595744680851, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1789375, Length=270, Percent_Identity=24.0740740740741, Blast_Score=68, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI71998625, Length=264, Percent_Identity=28.7878787878788, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17564128, Length=297, Percent_Identity=25.9259259259259, Blast_Score=100, Evalue=9e-22,
Organism=Caenorhabditis elegans, GI17550248, Length=288, Percent_Identity=25.6944444444444, Blast_Score=98, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI17566692, Length=288, Percent_Identity=26.7361111111111, Blast_Score=94, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI17561300, Length=278, Percent_Identity=26.978417266187, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17552492, Length=276, Percent_Identity=27.536231884058, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17561298, Length=279, Percent_Identity=25.8064516129032, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI212645785, Length=208, Percent_Identity=31.7307692307692, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17538386, Length=278, Percent_Identity=25.5395683453237, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17537077, Length=295, Percent_Identity=23.3898305084746, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17537075, Length=295, Percent_Identity=23.0508474576271, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17562292, Length=264, Percent_Identity=26.8939393939394, Blast_Score=68, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6324694, Length=291, Percent_Identity=29.2096219931272, Blast_Score=99, Evalue=7e-22,
Organism=Saccharomyces cerevisiae, GI6322556, Length=262, Percent_Identity=28.6259541984733, Blast_Score=94, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6320079, Length=239, Percent_Identity=28.4518828451883, Blast_Score=90, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6325169, Length=313, Percent_Identity=23.961661341853, Blast_Score=87, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6320576, Length=258, Percent_Identity=27.906976744186, Blast_Score=86, Evalue=8e-18,
Organism=Saccharomyces cerevisiae, GI6321896, Length=310, Percent_Identity=25.4838709677419, Blast_Score=80, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6323998, Length=202, Percent_Identity=27.2277227722772, Blast_Score=69, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6319958, Length=202, Percent_Identity=27.2277227722772, Blast_Score=69, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6323684, Length=151, Percent_Identity=33.112582781457, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6319951, Length=196, Percent_Identity=27.0408163265306, Blast_Score=67, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24657054, Length=256, Percent_Identity=32.8125, Blast_Score=113, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24662789, Length=300, Percent_Identity=29, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI21356425, Length=288, Percent_Identity=29.8611111111111, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI45553081, Length=281, Percent_Identity=27.4021352313167, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI281366140, Length=249, Percent_Identity=28.5140562248996, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24663317, Length=282, Percent_Identity=29.4326241134752, Blast_Score=101, Evalue=6e-22,
Organism=Drosophila melanogaster, GI20129731, Length=289, Percent_Identity=26.643598615917, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24644950, Length=301, Percent_Identity=27.5747508305648, Blast_Score=91, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24662781, Length=287, Percent_Identity=31.0104529616725, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24662785, Length=275, Percent_Identity=31.2727272727273, Blast_Score=85, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24646155, Length=219, Percent_Identity=28.7671232876712, Blast_Score=81, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24646159, Length=191, Percent_Identity=27.7486910994764, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 30313; Mature: 30313

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLCNKDVSQIGFGTWKIGGGYWNPDYSKDSHYIEILKYVISKGINVIDTAEMYGGGHSE
CCCCHHHHHHHCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEHHHHHCCCCHH
ELVGKAIENFDRDKIFIITKVWSNHLKYDDLIRSAKNSLKRLNAKYIDLYLIHWPNSSVP
HHHHHHHHHCCCCEEEEEEHHHHCCCCHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCC
LEESLRAMEELVDQGIVNCIGVSNFDIKLLEETMSITKKYEITANEIEYNVENKSAEKDV
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHEEEHHHEEEECCCCCCCCCC
IPFCERNNIKVIAYSPLARGNAKNNKILEEIGRKYNKTSVQVALNYLLRRSIPIPKASSK
CCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCCCH
DHIDEILGALGWNLSDEDYERISKI
HHHHHHHHHHCCCCCHHHHHHHHCC
>Mature Secondary Structure
MRLCNKDVSQIGFGTWKIGGGYWNPDYSKDSHYIEILKYVISKGINVIDTAEMYGGGHSE
CCCCHHHHHHHCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEHHHHHCCCCHH
ELVGKAIENFDRDKIFIITKVWSNHLKYDDLIRSAKNSLKRLNAKYIDLYLIHWPNSSVP
HHHHHHHHHCCCCEEEEEEHHHHCCCCHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCC
LEESLRAMEELVDQGIVNCIGVSNFDIKLLEETMSITKKYEITANEIEYNVENKSAEKDV
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHEEEHHHEEEECCCCCCCCCC
IPFCERNNIKVIAYSPLARGNAKNNKILEEIGRKYNKTSVQVALNYLLRRSIPIPKASSK
CCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCCCH
DHIDEILGALGWNLSDEDYERISKI
HHHHHHHHHHCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]