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The map label for this gene is dhg-3 [C]

Identifier: 15899906

GI number: 15899906

Start: 2949984

End: 2951066

Strand: Reverse

Name: dhg-3 [C]

Synonym: SSO3204

Alternate gene names: 15899906

Gene position: 2951066-2949984 (Counterclockwise)

Preceding gene: 15899909

Following gene: 15899904

Centisome position: 98.62

GC content: 35.46

Gene sequence:

>1083_bases
ATGAAGGCAATAGTAGTTAATCCACCAAACAAAGGAGTGCATGTTAAAGAGATAAACGATATACATCGATCACTCACCGC
AGATGAAGTTTTAGTTAAAACGATAGCAAATGGCATTTGTGGAACTGATCGTGGTATTGTTTCTGGCTTATTGAAATTCT
CTCGACCACCAAATGGAAAAAATGATTTAGTGTTAGGACATGAAAATTTGGGTCAAGTGATTGATAAGGGACCAGAGGTA
CATGGCTTAGGTAAAGGCGACTACGTAGTCTCGATAGTTAGAAGGGGATGTGGAAAGTGTTCCAATTGTTTAGCTGGAAG
GCAAGATTTTTGTGAAACTGGGGAATTTGTGGAAGCTGGAATTAGAGGTTTAGACGGTTTTATGAGGGAATTTTATATAG
ATAATGCAAGCTATTTAGTTAAAATACCAGATGAAATAGTTGATATCGCAGTTTTGCTTGAGCCACTTTCCAATGTGGTA
AAGGCTTATAGTGAGCTAATGCTAGTGCAAAGAAGAATGACATGGTGGTGTAAGGACGGCAGTTATAATTGTAGAAATGT
TGCAATAGTAGGATCTGGGCCAATAGGTCTCATGTTTTCCTTAATGTTCTCTATTCAAGGTTTTAATGCATTTGTTTTGA
ATAAGAGAGATCCTTTTCCAATTGAGGCTGAGATCGTAGAGAAGAGCAATGCTAAATTTATAAATACTAATAAAGATCGA
CTACCTAATACAATAGACTTACTTATAGACACTTCAGGGTATCCATCAGCGTTTATTCCCCTAATGAGTAGGTTAAACAA
GAACTCAGCAATTATACTATTTGGCACTACCGGTGGAGAGAAATTTGAGGTTAATGCTGATTTAATAACATATCTTGTAG
AAAATAACATTTTATTATTTGGGAGTGTTAATGCCAGTAAGAAGGACTTTGAAAACGGTGTGAATTATCTTACAATCTGG
AAATATAGATATCCAAGTGTATTAAATAGAATGATAACTAGAGTTATTAAACCAGAGCAAGCTCCAGAAGTATTATATAC
AAAACCCAAGGGAGAAATAAAGACAGTAATTTCATGGGTTTAA

Upstream 100 bases:

>100_bases
TAGATATTAGCTTCCTATAATCCTTAAGCGTGAGATAACTAAATTCATAATTGGTATTAAGTTCTCCTACGTTTAAAAAT
TTAAATGCGATTATACTTTT

Downstream 100 bases:

>100_bases
CTGTCTTCTCAATACCTCTATAGCTTTTTTAATTTCTTCCATTGATGCCTCATCTTCTAACGTCGAAATATCTCCTATAT
TAGATCCCGTCATAACAGCT

Product: glucose 1-dehydrogenase (dhg-3)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MKAIVVNPPNKGVHVKEINDIHRSLTADEVLVKTIANGICGTDRGIVSGLLKFSRPPNGKNDLVLGHENLGQVIDKGPEV
HGLGKGDYVVSIVRRGCGKCSNCLAGRQDFCETGEFVEAGIRGLDGFMREFYIDNASYLVKIPDEIVDIAVLLEPLSNVV
KAYSELMLVQRRMTWWCKDGSYNCRNVAIVGSGPIGLMFSLMFSIQGFNAFVLNKRDPFPIEAEIVEKSNAKFINTNKDR
LPNTIDLLIDTSGYPSAFIPLMSRLNKNSAIILFGTTGGEKFEVNADLITYLVENNILLFGSVNASKKDFENGVNYLTIW
KYRYPSVLNRMITRVIKPEQAPEVLYTKPKGEIKTVISWV

Sequences:

>Translated_360_residues
MKAIVVNPPNKGVHVKEINDIHRSLTADEVLVKTIANGICGTDRGIVSGLLKFSRPPNGKNDLVLGHENLGQVIDKGPEV
HGLGKGDYVVSIVRRGCGKCSNCLAGRQDFCETGEFVEAGIRGLDGFMREFYIDNASYLVKIPDEIVDIAVLLEPLSNVV
KAYSELMLVQRRMTWWCKDGSYNCRNVAIVGSGPIGLMFSLMFSIQGFNAFVLNKRDPFPIEAEIVEKSNAKFINTNKDR
LPNTIDLLIDTSGYPSAFIPLMSRLNKNSAIILFGTTGGEKFEVNADLITYLVENNILLFGSVNASKKDFENGVNYLTIW
KYRYPSVLNRMITRVIKPEQAPEVLYTKPKGEIKTVISWV
>Mature_360_residues
MKAIVVNPPNKGVHVKEINDIHRSLTADEVLVKTIANGICGTDRGIVSGLLKFSRPPNGKNDLVLGHENLGQVIDKGPEV
HGLGKGDYVVSIVRRGCGKCSNCLAGRQDFCETGEFVEAGIRGLDGFMREFYIDNASYLVKIPDEIVDIAVLLEPLSNVV
KAYSELMLVQRRMTWWCKDGSYNCRNVAIVGSGPIGLMFSLMFSIQGFNAFVLNKRDPFPIEAEIVEKSNAKFINTNKDR
LPNTIDLLIDTSGYPSAFIPLMSRLNKNSAIILFGTTGGEKFEVNADLITYLVENNILLFGSVNASKKDFENGVNYLTIW
KYRYPSVLNRMITRVIKPEQAPEVLYTKPKGEIKTVISWV

Specific function: Threonine catabolism; first step. [C]

COG id: COG1063

COG function: function code ER; Threonine dehydrogenase and related Zn-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790045, Length=262, Percent_Identity=26.7175572519084, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI87082125, Length=346, Percent_Identity=25.1445086705202, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI87081918, Length=177, Percent_Identity=33.3333333333333, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1787863, Length=355, Percent_Identity=25.6338028169014, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17562878, Length=193, Percent_Identity=27.979274611399, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N [H]

EC number: =1.1.1.47 [H]

Molecular weight: Translated: 39971; Mature: 39971

Theoretical pI: Translated: 8.25; Mature: 8.25

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAIVVNPPNKGVHVKEINDIHRSLTADEVLVKTIANGICGTDRGIVSGLLKFSRPPNGK
CCEEEECCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCC
NDLVLGHENLGQVIDKGPEVHGLGKGDYVVSIVRRGCGKCSNCLAGRQDFCETGEFVEAG
CCEEECHHHHHHHHHCCCCEECCCCCHHHHHHHHHHCCHHHHHHCCCHHHHHCHHHHHHH
IRGLDGFMREFYIDNASYLVKIPDEIVDIAVLLEPLSNVVKAYSELMLVQRRMTWWCKDG
HHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCC
SYNCRNVAIVGSGPIGLMFSLMFSIQGFNAFVLNKRDPFPIEAEIVEKSNAKFINTNKDR
CCCCCEEEEEECCCHHHHHHHHHHHCCCCEEEECCCCCCCCCHHEECCCCCEEEECCHHH
LPNTIDLLIDTSGYPSAFIPLMSRLNKNSAIILFGTTGGEKFEVNADLITYLVENNILLF
CCCEEEEEEECCCCCHHHHHHHHHCCCCCEEEEEECCCCCEEEECHHHHHHHHHCCEEEE
GSVNASKKDFENGVNYLTIWKYRYPSVLNRMITRVIKPEQAPEVLYTKPKGEIKTVISWV
ECCCCCHHHHHCCCCEEEEEEECCHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHCCC
>Mature Secondary Structure
MKAIVVNPPNKGVHVKEINDIHRSLTADEVLVKTIANGICGTDRGIVSGLLKFSRPPNGK
CCEEEECCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCC
NDLVLGHENLGQVIDKGPEVHGLGKGDYVVSIVRRGCGKCSNCLAGRQDFCETGEFVEAG
CCEEECHHHHHHHHHCCCCEECCCCCHHHHHHHHHHCCHHHHHHCCCHHHHHCHHHHHHH
IRGLDGFMREFYIDNASYLVKIPDEIVDIAVLLEPLSNVVKAYSELMLVQRRMTWWCKDG
HHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCC
SYNCRNVAIVGSGPIGLMFSLMFSIQGFNAFVLNKRDPFPIEAEIVEKSNAKFINTNKDR
CCCCCEEEEEECCCHHHHHHHHHHHCCCCEEEECCCCCCCCCHHEECCCCCEEEECCHHH
LPNTIDLLIDTSGYPSAFIPLMSRLNKNSAIILFGTTGGEKFEVNADLITYLVENNILLF
CCCEEEEEEECCCCCHHHHHHHHHCCCCCEEEEEECCCCCEEEECHHHHHHHHHCCEEEE
GSVNASKKDFENGVNYLTIWKYRYPSVLNRMITRVIKPEQAPEVLYTKPKGEIKTVISWV
ECCCCCHHHHHCCCCEEEEEEECCHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8436115; 11029001; 2803257 [H]