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The map label for this gene is sdhB [H]

Identifier: 15899115

GI number: 15899115

Start: 2152400

End: 2153350

Strand: Direct

Name: sdhB [H]

Synonym: SSO2357

Alternate gene names: 15899115

Gene position: 2152400-2153350 (Clockwise)

Preceding gene: 15899114

Following gene: 15899116

Centisome position: 71.93

GC content: 37.22

Gene sequence:

>951_bases
ATGACTCAGTCTCAAGAGGAAGAAGTTATATTAAAGGTAAAAAGATTTAACCCAGAAAAGGGATATTGGTGGGCGGAATA
TAAGCTGAAGGTTGATAGATTTACGCAATTCACAGAGGCACTAAGGAGAATAAAAAGTGAACAAGATCCTACGTTATCCT
ATAGGGCATCATGTCATATGGCAGTATGTGGAAGTTGTGGGATGAAAATCAATGGTGAACCTAGATTAGCTTGTAAAACC
TTAGTTTTGGATGTAGTCAAAAAATACAATAATAATGTAATAACAATTGAGCCAATGGATTATTTCAAACCAATTAAGGA
CTTAATAGTTGACTGGGATGAGTTTTACGAAAGGATGTTTAAGATAAAACCCAGACTATATCAAGCTAAGGAGGTATTAG
AGGGTAAAGCTGAGCATAGACTTAAACCAGAGGATCAGAGAGAGTTATGGAAATTTGCTCAGTGCATATGGTGCGGGTTG
TGTGTCTCAGCTTGTCCAGCGGTTGTAATAGATCAGCAATTTTTAGGTCCAGCTGCTCATGCTAAGGGTTATAGATTCTT
AGCAGATCCAAGGGATACGATAACTGAAGAGAGAATGAAAATACTAATTGATAGTTCATGGCGTTGTACTTATTGTTATC
AATGCTTTAATGTGTGTCCCAGAGATATAGAGCCAGTAACTGCAATAAAGAAAACGAGAAGTTTCACTAAAACATACAAA
GACAAATCGGAAATAGCGGAAAGAGGTGAAAAGCATGTTGAAGCCATTCATGAATCTATATTAAAAACCGGGAAGCTCGC
AGAGGCACCAGTATATTTAAAGACCTATGGGGTACTGCAATCGCTTGTCGATCTAGTGTACATGTCAAAGACAGGGAAGC
TTAAATACGCATTAGTTCAAGAGAGACCTGTACAAAATATAAACGAAATCAAAAAGATTATAGGTGAGTGA

Upstream 100 bases:

>100_bases
TTAAAACACACAATTGCGTATTTAAGGGGTAATACGGTTGAGGTTACATTCAAACCAGTTAAGATAACCAGATGGAAACC
AGAACCTAGGGTGTATTAAA

Downstream 100 bases:

>100_bases
TAGGAATGAAAATAGCTTATTATCCTGGATGTGCAACCCATGGTCTATCTAAGGATGTAGATATAGCCACAAAAAAGGTA
GCAGAAGTACTTGGGGTTGA

Product: succinate dehydrogenase iron-sulfur subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MTQSQEEEVILKVKRFNPEKGYWWAEYKLKVDRFTQFTEALRRIKSEQDPTLSYRASCHMAVCGSCGMKINGEPRLACKT
LVLDVVKKYNNNVITIEPMDYFKPIKDLIVDWDEFYERMFKIKPRLYQAKEVLEGKAEHRLKPEDQRELWKFAQCIWCGL
CVSACPAVVIDQQFLGPAAHAKGYRFLADPRDTITEERMKILIDSSWRCTYCYQCFNVCPRDIEPVTAIKKTRSFTKTYK
DKSEIAERGEKHVEAIHESILKTGKLAEAPVYLKTYGVLQSLVDLVYMSKTGKLKYALVQERPVQNINEIKKIIGE

Sequences:

>Translated_316_residues
MTQSQEEEVILKVKRFNPEKGYWWAEYKLKVDRFTQFTEALRRIKSEQDPTLSYRASCHMAVCGSCGMKINGEPRLACKT
LVLDVVKKYNNNVITIEPMDYFKPIKDLIVDWDEFYERMFKIKPRLYQAKEVLEGKAEHRLKPEDQRELWKFAQCIWCGL
CVSACPAVVIDQQFLGPAAHAKGYRFLADPRDTITEERMKILIDSSWRCTYCYQCFNVCPRDIEPVTAIKKTRSFTKTYK
DKSEIAERGEKHVEAIHESILKTGKLAEAPVYLKTYGVLQSLVDLVYMSKTGKLKYALVQERPVQNINEIKKIIGE
>Mature_315_residues
TQSQEEEVILKVKRFNPEKGYWWAEYKLKVDRFTQFTEALRRIKSEQDPTLSYRASCHMAVCGSCGMKINGEPRLACKTL
VLDVVKKYNNNVITIEPMDYFKPIKDLIVDWDEFYERMFKIKPRLYQAKEVLEGKAEHRLKPEDQRELWKFAQCIWCGLC
VSACPAVVIDQQFLGPAAHAKGYRFLADPRDTITEERMKILIDSSWRCTYCYQCFNVCPRDIEPVTAIKKTRSFTKTYKD
KSEIAERGEKHVEAIHESILKTGKLAEAPVYLKTYGVLQSLVDLVYMSKTGKLKYALVQERPVQNINEIKKIIGE

Specific function: Two Distinct, Membrane-Bound, FAD-Containing Enzymes Are Responsible For The Catalysis Of Fumarate And Succinate Interconversion; The Fumarate Reductase Is Used In Anaerobic Growth, And The Succinate Dehydrogenase Is Used In Aerobic Growth. [C]

COG id: COG0479

COG function: function code C; Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI115387094, Length=207, Percent_Identity=36.7149758454106, Blast_Score=134, Evalue=2e-31,
Organism=Escherichia coli, GI1790596, Length=227, Percent_Identity=35.6828193832599, Blast_Score=147, Evalue=8e-37,
Organism=Escherichia coli, GI1786943, Length=232, Percent_Identity=35.3448275862069, Blast_Score=132, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17533915, Length=239, Percent_Identity=30.5439330543933, Blast_Score=119, Evalue=3e-27,
Organism=Saccharomyces cerevisiae, GI6322987, Length=236, Percent_Identity=32.6271186440678, Blast_Score=118, Evalue=1e-27,
Organism=Drosophila melanogaster, GI17137106, Length=209, Percent_Identity=33.0143540669856, Blast_Score=125, Evalue=4e-29,
Organism=Drosophila melanogaster, GI24643156, Length=211, Percent_Identity=33.175355450237, Blast_Score=122, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR004489 [H]

Pfam domain/function: NA

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 36792; Mature: 36661

Theoretical pI: Translated: 8.73; Mature: 8.73

Prosite motif: PS00197 2FE2S_FER_1 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
3.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQSQEEEVILKVKRFNPEKGYWWAEYKLKVDRFTQFTEALRRIKSEQDPTLSYRASCHM
CCCCCCHHHHHHHHHCCCCCCEEEEEEEEEHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
AVCGSCGMKINGEPRLACKTLVLDVVKKYNNNVITIEPMDYFKPIKDLIVDWDEFYERMF
HHHCCCCCEECCCCHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHCCHHHHHHHHH
KIKPRLYQAKEVLEGKAEHRLKPEDQRELWKFAQCIWCGLCVSACPAVVIDQQFLGPAAH
HHCHHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHH
AKGYRFLADPRDTITEERMKILIDSSWRCTYCYQCFNVCPRDIEPVTAIKKTRSFTKTYK
CCCCEEECCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHC
DKSEIAERGEKHVEAIHESILKTGKLAEAPVYLKTYGVLQSLVDLVYMSKTGKLKYALVQ
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEH
ERPVQNINEIKKIIGE
HCCCCHHHHHHHHHCC
>Mature Secondary Structure 
TQSQEEEVILKVKRFNPEKGYWWAEYKLKVDRFTQFTEALRRIKSEQDPTLSYRASCHM
CCCCCHHHHHHHHHCCCCCCEEEEEEEEEHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
AVCGSCGMKINGEPRLACKTLVLDVVKKYNNNVITIEPMDYFKPIKDLIVDWDEFYERMF
HHHCCCCCEECCCCHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHCCHHHHHHHHH
KIKPRLYQAKEVLEGKAEHRLKPEDQRELWKFAQCIWCGLCVSACPAVVIDQQFLGPAAH
HHCHHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHH
AKGYRFLADPRDTITEERMKILIDSSWRCTYCYQCFNVCPRDIEPVTAIKKTRSFTKTYK
CCCCEEECCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHC
DKSEIAERGEKHVEAIHESILKTGKLAEAPVYLKTYGVLQSLVDLVYMSKTGKLKYALVQ
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEH
ERPVQNINEIKKIIGE
HCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]