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The map label for this gene is hisE [H]

Identifier: 15897515

GI number: 15897515

Start: 524697

End: 524990

Strand: Direct

Name: hisE [H]

Synonym: SSO6223

Alternate gene names: 15897515

Gene position: 524697-524990 (Clockwise)

Preceding gene: 15897514

Following gene: 15897516

Centisome position: 17.54

GC content: 36.39

Gene sequence:

>294_bases
GTGCACGATATGAGTAATGAAATAGTAGATGAATTATACAAAATCATACTTGATAGGATAGAAAAGAGGCCGACTGGTAG
TTACACTGCTGAGATTGTAAATAAGGGAAAACCATACGTAGCGAGGAAGGTTGGCGAAGAATCTGTAGAAACAATAGTAG
CATCTCTAGCAGAAAATAAGGAGAGATTTATAAGTGAGGTCGCTGATCTAATCTATCATTTATTAGTATTAATGGCATTA
GAAGGCGTAACACCAGAGGATATTTATAGAGAGTTAGAGAGGAGGAGAAAATGA

Upstream 100 bases:

>100_bases
ACAATGTACGCTAATGTCCGTGATATAAATAAACAGCTACTTGAAGCATCTATTTCCTTAGCAAACTATGAGGGATTCAT
AATTCATGGTAAAAGTATAG

Downstream 100 bases:

>100_bases
AGGCATTAGTAATTAATTATGGTGTAGGTAATTTATATAGTATCTCATCTGCTCTAAAAAGAGTAGGATTTGAAGTAACA
ATAGATAATAAACCAAGGAA

Product: phosphoribosyl-ATP cyclohydrolase (hisE)

Products: NA

Alternate protein names: PRA-PH [H]

Number of amino acids: Translated: 97; Mature: 97

Protein sequence:

>97_residues
MHDMSNEIVDELYKIILDRIEKRPTGSYTAEIVNKGKPYVARKVGEESVETIVASLAENKERFISEVADLIYHLLVLMAL
EGVTPEDIYRELERRRK

Sequences:

>Translated_97_residues
MHDMSNEIVDELYKIILDRIEKRPTGSYTAEIVNKGKPYVARKVGEESVETIVASLAENKERFISEVADLIYHLLVLMAL
EGVTPEDIYRELERRRK
>Mature_97_residues
MHDMSNEIVDELYKIILDRIEKRPTGSYTAEIVNKGKPYVARKVGEESVETIVASLAENKERFISEVADLIYHLLVLMAL
EGVTPEDIYRELERRRK

Specific function: Histidine biosynthesis; second step. Histidine biosynthesis; third step. [C]

COG id: COG0140

COG function: function code E; Phosphoribosyl-ATP pyrophosphohydrolase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PRA-PH family [H]

Homologues:

Organism=Escherichia coli, GI2367128, Length=87, Percent_Identity=34.4827586206897, Blast_Score=61, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008179
- InterPro:   IPR021130 [H]

Pfam domain/function: PF01503 PRA-PH [H]

EC number: =3.6.1.31 [H]

Molecular weight: Translated: 11236; Mature: 11236

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHDMSNEIVDELYKIILDRIEKRPTGSYTAEIVNKGKPYVARKVGEESVETIVASLAENK
CCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
ERFISEVADLIYHLLVLMALEGVTPEDIYRELERRRK
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MHDMSNEIVDELYKIILDRIEKRPTGSYTAEIVNKGKPYVARKVGEESVETIVASLAENK
CCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
ERFISEVADLIYHLLVLMALEGVTPEDIYRELERRRK
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA