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The map label for this gene is tlyC [H]

Identifier: 15893064

GI number: 15893064

Start: 1053836

End: 1054735

Strand: Reverse

Name: tlyC [H]

Synonym: RC1141

Alternate gene names: 15893064

Gene position: 1054735-1053836 (Counterclockwise)

Preceding gene: 15893065

Following gene: 15893062

Centisome position: 83.13

GC content: 31.22

Gene sequence:

>900_bases
ATGTTAAAATCTTCAAAAAAAGAAGATTCTAGTAAAAAAAATCAAAATAATAAGTTAATTTTTACTGTACGAAAATTATT
CTCTCCGATAAAAAATTTTTTTAGAAAAACAAAAACGCCCGATAATTTTTTTGGTGTCATAAAACGCCTTAAAATTAATA
GCCAAAAAATGACTTTAGACGAGCGTAATATTTTAGCTAATTTATTGGAGCTAGAAGATAAAACTATTGAAGATATAATG
GTACCGCGTTCCGATATTGCGGCAATAAAATTAACTACGAATCTAGAAGAATTAAGTGAGTCTATTAAGTTAGAAGTCCC
ACATACACGAACTCTTATATATGACGGTACTTTGGATAATGTAGTAGGGTTCATTCATATCAAGGATTTATTTAAAGCAT
TGGCTACAAAGCAAAACGGTCGTTTAAAAAAGCTTATACGTAAGCATATAATTGCAGCTCCTTCTATGAAATTATTAGAT
TTGCTAGCAAAAATGCGTCGTGAGAGAACACATATTGCAATAGTTGTTGATGAATATGGCGGTACTGACGGTTTAGTTAC
TATTGAAGATCTGATAGAAGAAATAGTAGGACGAATAGATGATGAGCATGATCAGCAATTAGATAGCGATAATTTCAAGG
TTATTAATAACTCAACAATTATTGCAAATGCACGTGTTGAAGTAGAAGTGCTTGAAGAAATAATAGGAGAAAAGCTACAC
AATGATTATGATGAATTTGATACGATAGGTGGATTAGTATTGACTAGAGTCAGTAGTGTTCCGGCTATCGGTACTAGAAT
AGATATTTCAGAAAATATTGAAATTGAAGTTACAGACGCAACTCCTCGTTCTTTAAAACAAGTCAAAATTAGACTAAAAA
ACGGTTTGAATGGTCAATGA

Upstream 100 bases:

>100_bases
CATCAAAATGACACAGAAGCAAATATTATGGAAAATCTAGAAATTGAAATATTATCATATTTCGGTATTTTCCCCCCTTA
TTAACTAAATAAAAAAATTT

Downstream 100 bases:

>100_bases
ATACGAATTTAGAGTCGGTGTGTCCTCTAAATTCGTTAAAAATATTTTATTATTATATTGCAGCTTGTGCTTCATTTCCT
ATCATCGGACTTTCTTGCGA

Product: hemolysin C

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MLKSSKKEDSSKKNQNNKLIFTVRKLFSPIKNFFRKTKTPDNFFGVIKRLKINSQKMTLDERNILANLLELEDKTIEDIM
VPRSDIAAIKLTTNLEELSESIKLEVPHTRTLIYDGTLDNVVGFIHIKDLFKALATKQNGRLKKLIRKHIIAAPSMKLLD
LLAKMRRERTHIAIVVDEYGGTDGLVTIEDLIEEIVGRIDDEHDQQLDSDNFKVINNSTIIANARVEVEVLEEIIGEKLH
NDYDEFDTIGGLVLTRVSSVPAIGTRIDISENIEIEVTDATPRSLKQVKIRLKNGLNGQ

Sequences:

>Translated_299_residues
MLKSSKKEDSSKKNQNNKLIFTVRKLFSPIKNFFRKTKTPDNFFGVIKRLKINSQKMTLDERNILANLLELEDKTIEDIM
VPRSDIAAIKLTTNLEELSESIKLEVPHTRTLIYDGTLDNVVGFIHIKDLFKALATKQNGRLKKLIRKHIIAAPSMKLLD
LLAKMRRERTHIAIVVDEYGGTDGLVTIEDLIEEIVGRIDDEHDQQLDSDNFKVINNSTIIANARVEVEVLEEIIGEKLH
NDYDEFDTIGGLVLTRVSSVPAIGTRIDISENIEIEVTDATPRSLKQVKIRLKNGLNGQ
>Mature_299_residues
MLKSSKKEDSSKKNQNNKLIFTVRKLFSPIKNFFRKTKTPDNFFGVIKRLKINSQKMTLDERNILANLLELEDKTIEDIM
VPRSDIAAIKLTTNLEELSESIKLEVPHTRTLIYDGTLDNVVGFIHIKDLFKALATKQNGRLKKLIRKHIIAAPSMKLLD
LLAKMRRERTHIAIVVDEYGGTDGLVTIEDLIEEIVGRIDDEHDQQLDSDNFKVINNSTIIANARVEVEVLEEIIGEKLH
NDYDEFDTIGGLVLTRVSSVPAIGTRIDISENIEIEVTDATPRSLKQVKIRLKNGLNGQ

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=202, Percent_Identity=34.1584158415842, Blast_Score=107, Evalue=1e-23,
Organism=Escherichia coli, GI1786879, Length=236, Percent_Identity=31.7796610169492, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI145693175, Length=251, Percent_Identity=28.6852589641434, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI87082033, Length=229, Percent_Identity=29.2576419213974, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1788119, Length=234, Percent_Identity=25.6410256410256, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1790664, Length=209, Percent_Identity=23.9234449760766, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC [H]

EC number: NA

Molecular weight: Translated: 33925; Mature: 33925

Theoretical pI: Translated: 7.19; Mature: 7.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKSSKKEDSSKKNQNNKLIFTVRKLFSPIKNFFRKTKTPDNFFGVIKRLKINSQKMTLD
CCCCCCCCCCHHCCCCCCEEEEHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCH
ERNILANLLELEDKTIEDIMVPRSDIAAIKLTTNLEELSESIKLEVPHTRTLIYDGTLDN
HHHHHHHHHHHCCHHHHHHHCCCCCCEEEEEECCHHHHHHHCEEECCCCEEEEECCCHHH
VVGFIHIKDLFKALATKQNGRLKKLIRKHIIAAPSMKLLDLLAKMRRERTHIAIVVDEYG
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEEEECCC
GTDGLVTIEDLIEEIVGRIDDEHDQQLDSDNFKVINNSTIIANARVEVEVLEEIIGEKLH
CCCCEEEHHHHHHHHHHHCCCHHHHHCCCCCEEEEECCEEEEECEEHHHHHHHHHHHHHH
NDYDEFDTIGGLVLTRVSSVPAIGTRIDISENIEIEVTDATPRSLKQVKIRLKNGLNGQ
CCHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEEEECCCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MLKSSKKEDSSKKNQNNKLIFTVRKLFSPIKNFFRKTKTPDNFFGVIKRLKINSQKMTLD
CCCCCCCCCCHHCCCCCCEEEEHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCH
ERNILANLLELEDKTIEDIMVPRSDIAAIKLTTNLEELSESIKLEVPHTRTLIYDGTLDN
HHHHHHHHHHHCCHHHHHHHCCCCCCEEEEEECCHHHHHHHCEEECCCCEEEEECCCHHH
VVGFIHIKDLFKALATKQNGRLKKLIRKHIIAAPSMKLLDLLAKMRRERTHIAIVVDEYG
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEEEECCC
GTDGLVTIEDLIEEIVGRIDDEHDQQLDSDNFKVINNSTIIANARVEVEVLEEIIGEKLH
CCCCEEEHHHHHHHHHHHCCCHHHHHCCCCCEEEEECCEEEEECEEHHHHHHHHHHHHHH
NDYDEFDTIGGLVLTRVSSVPAIGTRIDISENIEIEVTDATPRSLKQVKIRLKNGLNGQ
CCHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEEEECCCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA