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The map label for this gene is nuoC

Identifier: 15892406

GI number: 15892406

Start: 479086

End: 479814

Strand: Reverse

Name: nuoC

Synonym: RC0483

Alternate gene names: 15892406

Gene position: 479814-479086 (Counterclockwise)

Preceding gene: 15892407

Following gene: 161723847

Centisome position: 37.82

GC content: 36.49

Gene sequence:

>729_bases
ATGACGCTAGACAAACTCATTGAAAAACTTGCAGCTAAATCTAGCATTTTAATAACTCCGATCACGGTTAAAGATTACCT
AGCTTATAAAATCGAGCCGAATTTTTTATTGCCGTTTTTAAAAGCTTTAAAAGAATCGGAAGAATTACGCTTCACTTTAC
TTACTGATTTATTTGGGGCTGATTTTCCTCAGAATAACGTAGTCAATTCAGTTGGGCTTGGCCACAAGGAGCAAGGCGCG
AAGCCTATAACTAATAGGAGAACGACGAGCGACAATGTAGGCGAGTCCAAATCAATTGACTATAAAAGGTTTGAAGTAGT
ATATAATTTATTAAGCTTAAAATTAAATAAGCGTCTTATAATAAAAGTATATATATCTGAAAAAGAAACTATACCTTCAG
CAATGAATATATTTAGTGCCGCTTGTTGGTATGAGCGTGAAGTTTATGATATGTACGGGGTAAATTTCGAGGGTAATGAC
GATAAAAGACGCATACTAACCGATTACGAATTTGAGGGACATCCATTACGTAAAGATTTCCCGTTAACAGGCTATACACA
AGTTAAATATGATGAGAAGCTAAAGAAAGTAGCTTATGAACCGGTCGATTTAGACATAGAATATCGTGAGTTTGATTTTA
GTTCGCACTGGCATAGCCCGAGTTATGTATTGCCAGGTGATGAGAAGGCAACCGATGTCATTCCTGCGAAAGCAGGAATC
CAGAAATAA

Upstream 100 bases:

>100_bases
GTTGACGTATATGTCCCTGGCTGCCCTCCTACCGCCGAAGCATTAATTTACGGGCTGATGCAGTTACAGAAAAAAATTAA
ACGCACTACAGGTTTTAAGT

Downstream 100 bases:

>100_bases
AATGAATGTCATCCTGTGACTTGATCGCGGGATCCAGAAAAAATACAAAAGACTGGACCCCGTGGTCAAGCGAACTAGGT
GACAGTAGGAAAAATACTAT

Product: NADH dehydrogenase subunit C

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C; NDH-1 subunit C

Number of amino acids: Translated: 242; Mature: 241

Protein sequence:

>242_residues
MTLDKLIEKLAAKSSILITPITVKDYLAYKIEPNFLLPFLKALKESEELRFTLLTDLFGADFPQNNVVNSVGLGHKEQGA
KPITNRRTTSDNVGESKSIDYKRFEVVYNLLSLKLNKRLIIKVYISEKETIPSAMNIFSAACWYEREVYDMYGVNFEGND
DKRRILTDYEFEGHPLRKDFPLTGYTQVKYDEKLKKVAYEPVDLDIEYREFDFSSHWHSPSYVLPGDEKATDVIPAKAGI
QK

Sequences:

>Translated_242_residues
MTLDKLIEKLAAKSSILITPITVKDYLAYKIEPNFLLPFLKALKESEELRFTLLTDLFGADFPQNNVVNSVGLGHKEQGA
KPITNRRTTSDNVGESKSIDYKRFEVVYNLLSLKLNKRLIIKVYISEKETIPSAMNIFSAACWYEREVYDMYGVNFEGND
DKRRILTDYEFEGHPLRKDFPLTGYTQVKYDEKLKKVAYEPVDLDIEYREFDFSSHWHSPSYVLPGDEKATDVIPAKAGI
QK
>Mature_241_residues
TLDKLIEKLAAKSSILITPITVKDYLAYKIEPNFLLPFLKALKESEELRFTLLTDLFGADFPQNNVVNSVGLGHKEQGAK
PITNRRTTSDNVGESKSIDYKRFEVVYNLLSLKLNKRLIIKVYISEKETIPSAMNIFSAACWYEREVYDMYGVNFEGNDD
KRRILTDYEFEGHPLRKDFPLTGYTQVKYDEKLKKVAYEPVDLDIEYREFDFSSHWHSPSYVLPGDEKATDVIPAKAGIQ
K

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family

Homologues:

Organism=Homo sapiens, GI4758788, Length=206, Percent_Identity=39.3203883495146, Blast_Score=154, Evalue=6e-38,
Organism=Escherichia coli, GI145693162, Length=106, Percent_Identity=33.9622641509434, Blast_Score=81, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI32563621, Length=195, Percent_Identity=40.5128205128205, Blast_Score=145, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI71990788, Length=195, Percent_Identity=40.5128205128205, Blast_Score=145, Evalue=2e-35,
Organism=Drosophila melanogaster, GI24656494, Length=223, Percent_Identity=38.1165919282511, Blast_Score=154, Evalue=5e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUOC_RICCN (Q92ID7)

Other databases:

- EMBL:   AE006914
- PIR:   C97760
- RefSeq:   NP_360120.1
- ProteinModelPortal:   Q92ID7
- SMR:   Q92ID7
- GeneID:   928702
- GenomeReviews:   AE006914_GR
- KEGG:   rco:RC0483
- NMPDR:   fig|272944.1.peg.483
- OMA:   LTGYTQV
- ProtClustDB:   PRK06074
- BioCyc:   RCON272944:RC0483-MONOMER
- BRENDA:   1.6.99.5
- GO:   GO:0006810
- HAMAP:   MF_01357
- InterPro:   IPR010218
- InterPro:   IPR001268
- InterPro:   IPR022436
- ProDom:   PD001581
- TIGRFAMs:   TIGR01961
- TIGRFAMs:   TIGR03774

Pfam domain/function: PF00329 Complex1_30kDa

EC number: =1.6.99.5

Molecular weight: Translated: 27895; Mature: 27764

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: PS00542 COMPLEX1_30K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLDKLIEKLAAKSSILITPITVKDYLAYKIEPNFLLPFLKALKESEELRFTLLTDLFGA
CCHHHHHHHHHCCCCEEEEEEEHHHEEEEEECCCHHHHHHHHHCCCHHHHHHHHHHHHCC
DFPQNNVVNSVGLGHKEQGAKPITNRRTTSDNVGESKSIDYKRFEVVYNLLSLKLNKRLI
CCCCCCCHHHHCCCCHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEE
IKVYISEKETIPSAMNIFSAACWYEREVYDMYGVNFEGNDDKRRILTDYEFEGHPLRKDF
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCCCCCC
PLTGYTQVKYDEKLKKVAYEPVDLDIEYREFDFSSHWHSPSYVLPGDEKATDVIPAKAGI
CCCCCEECHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCEEECCCCCCCEECCCCCCC
QK
CC
>Mature Secondary Structure 
TLDKLIEKLAAKSSILITPITVKDYLAYKIEPNFLLPFLKALKESEELRFTLLTDLFGA
CHHHHHHHHHCCCCEEEEEEEHHHEEEEEECCCHHHHHHHHHCCCHHHHHHHHHHHHCC
DFPQNNVVNSVGLGHKEQGAKPITNRRTTSDNVGESKSIDYKRFEVVYNLLSLKLNKRLI
CCCCCCCHHHHCCCCHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEE
IKVYISEKETIPSAMNIFSAACWYEREVYDMYGVNFEGNDDKRRILTDYEFEGHPLRKDF
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCCCCCC
PLTGYTQVKYDEKLKKVAYEPVDLDIEYREFDFSSHWHSPSYVLPGDEKATDVIPAKAGI
CCCCCEECHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCEEECCCCCCCEECCCCCCC
QK
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11557893