Click here to switch to the map view.

The map label for this gene is kdtA

Identifier: 15892041

GI number: 15892041

Start: 115894

End: 117288

Strand: Reverse

Name: kdtA

Synonym: RC0118

Alternate gene names: 15892041

Gene position: 117288-115894 (Counterclockwise)

Preceding gene: 15892042

Following gene: 15892033

Centisome position: 9.24

GC content: 33.76

Gene sequence:

>1395_bases
ATGATGTTATTATATTATGCTTTAAGCTTTATATTATTACCTGTTTATTTTATCATAATTCTTATACGTTTATTAATAGG
TAAAGAAGATATAAGACGCATCCAAGAGCGTTTTGCTATTGGCAAACACAGACAAGACGATTCATTAGACTTCATGCAAA
CGTCCGCTAATAAAGAGGAATTTAAAGGAGACACTTCACTGCGAACCACAACGTATACACTAATACGTGAGGATGAAGGG
TTAGGATCAACGTATAAATTACCTTTAGAAGCAAGTGATGCACGAAGGCTGATATGGATTAATGCAGCAAGCATTGGCGA
GTCTATGGTAGCTTTAACATTAATACATAATATAAGTAAACGCTACCCTGACGTTCGTTTTCTAGTAACTTCTTGGACTA
ACAGCTCCGCTAAAATATTAACTGCCAAATTACCTAAAATAGCAGTTCACCAATTTTTACCGATAGATAATATTATTTTT
ACTCGAAAATTTTTAAGAAATTGGCAACCTGATTTAGGCATTTTTATAGAATCGGAATTATGGCCGTGTACTATTAATGA
GGGAGCAAAGCAGTGTAAATTACTACTAGTTAATGCTCGTATTTCCGATAAATCGTTTAAAGCTTGGCTACAAAGAAAAA
GCTTTTTTCAGCTTATTCTCAAAAATTGCAGTAAAATTATCGTGCAAAGCGAACGTGACTTACAAAAATTCAATGAACTT
GGCGTATCAGATGCAGTGAATTTAGGCAATATTAAATTTGCCAACGAAAAACTTCCGGTTAATCAAGAAGAGTTATCAAA
ATTAAGCTTACATTTAGACAATAAGCGAGTCGTGCTATTTGCCAGCACTCATCCCGAAGATGAAGAGGTGATTTTGCCCA
TAATCAAAAACCTAAAAGAGCAGTTTTTAGACTGCTATATTATCTTAATTCCAAGACATCCTGAGCGAGTTAAATCAATT
ATCGATAATTGTAAGTCACATAATTTATCCGCTACCGCTAAGTCACAAAATGATTTACCTGTTTTAAGCGATGATCTTTA
TATAGTTGATAGGTTCGGCGAAATGGGACTATTTTTTTCTGTAGCTACAATTTCTTTTATCGGCGGTTCTTTTAAACAAG
GCGGGCATAATATTTTAGAAGCAGCATATTTCTCTAATTGTATTATATTCGGTCCCGATATGAGCAAAAACACTGATATC
GCTAAAGGCGTACTGCAAAATGAAGCAGCTATCCAAATCAAAAACGGTGAAGATTTACTAACTAAACTAACATATCTACT
CAGGTCTAATAATGCTCTAGAACTTACAACTTACCGCGAAAATGCTTTAAAATTTATTAAGGACAACCAAAAAGTCCTAG
ATGAATATTTAAACGTAATTACGAAGTTTCTTTGA

Upstream 100 bases:

>100_bases
AAATCATAGTTGGCTCGCCTTTAGAACTCACAAATGATAAAATACAAAACCATATAAGCCTTGAACAACAATTAGCAAGC
TTAACAGAAAGTTTAAAGAA

Downstream 100 bases:

>100_bases
TAGAATTTAACTAAAAACTCTTATTCTCCTAAAAGCTCTATAGTAAATTCAGGATCTACGTGACTGATTTCTATACTTCC
GTTATTTTCTAGTATTTTCT

Product: 3-deoxy-D-manno-octulosonic-acid transferase

Products: NA

Alternate protein names: KDO transferase

Number of amino acids: Translated: 464; Mature: 464

Protein sequence:

>464_residues
MMLLYYALSFILLPVYFIIILIRLLIGKEDIRRIQERFAIGKHRQDDSLDFMQTSANKEEFKGDTSLRTTTYTLIREDEG
LGSTYKLPLEASDARRLIWINAASIGESMVALTLIHNISKRYPDVRFLVTSWTNSSAKILTAKLPKIAVHQFLPIDNIIF
TRKFLRNWQPDLGIFIESELWPCTINEGAKQCKLLLVNARISDKSFKAWLQRKSFFQLILKNCSKIIVQSERDLQKFNEL
GVSDAVNLGNIKFANEKLPVNQEELSKLSLHLDNKRVVLFASTHPEDEEVILPIIKNLKEQFLDCYIILIPRHPERVKSI
IDNCKSHNLSATAKSQNDLPVLSDDLYIVDRFGEMGLFFSVATISFIGGSFKQGGHNILEAAYFSNCIIFGPDMSKNTDI
AKGVLQNEAAIQIKNGEDLLTKLTYLLRSNNALELTTYRENALKFIKDNQKVLDEYLNVITKFL

Sequences:

>Translated_464_residues
MMLLYYALSFILLPVYFIIILIRLLIGKEDIRRIQERFAIGKHRQDDSLDFMQTSANKEEFKGDTSLRTTTYTLIREDEG
LGSTYKLPLEASDARRLIWINAASIGESMVALTLIHNISKRYPDVRFLVTSWTNSSAKILTAKLPKIAVHQFLPIDNIIF
TRKFLRNWQPDLGIFIESELWPCTINEGAKQCKLLLVNARISDKSFKAWLQRKSFFQLILKNCSKIIVQSERDLQKFNEL
GVSDAVNLGNIKFANEKLPVNQEELSKLSLHLDNKRVVLFASTHPEDEEVILPIIKNLKEQFLDCYIILIPRHPERVKSI
IDNCKSHNLSATAKSQNDLPVLSDDLYIVDRFGEMGLFFSVATISFIGGSFKQGGHNILEAAYFSNCIIFGPDMSKNTDI
AKGVLQNEAAIQIKNGEDLLTKLTYLLRSNNALELTTYRENALKFIKDNQKVLDEYLNVITKFL
>Mature_464_residues
MMLLYYALSFILLPVYFIIILIRLLIGKEDIRRIQERFAIGKHRQDDSLDFMQTSANKEEFKGDTSLRTTTYTLIREDEG
LGSTYKLPLEASDARRLIWINAASIGESMVALTLIHNISKRYPDVRFLVTSWTNSSAKILTAKLPKIAVHQFLPIDNIIF
TRKFLRNWQPDLGIFIESELWPCTINEGAKQCKLLLVNARISDKSFKAWLQRKSFFQLILKNCSKIIVQSERDLQKFNEL
GVSDAVNLGNIKFANEKLPVNQEELSKLSLHLDNKRVVLFASTHPEDEEVILPIIKNLKEQFLDCYIILIPRHPERVKSI
IDNCKSHNLSATAKSQNDLPVLSDDLYIVDRFGEMGLFFSVATISFIGGSFKQGGHNILEAAYFSNCIIFGPDMSKNTDI
AKGVLQNEAAIQIKNGEDLLTKLTYLLRSNNALELTTYRENALKFIKDNQKVLDEYLNVITKFL

Specific function: Essential step in lipopolysaccharides biosynthesis. Acts at transfer of 3-deoxy-D-mono octulonic acid (KDO) from CMP-KDO to a tetraacyldisaccharide 1,4'-bisphosphate precursor of lipid A (lipid IVA)

COG id: COG1519

COG function: function code M; 3-deoxy-D-manno-octulosonic-acid transferase

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RPE1 insert domain

Homologues:

Organism=Escherichia coli, GI1790064, Length=385, Percent_Identity=28.5714285714286, Blast_Score=171, Evalue=6e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KDTA_RICCN (Q92JE9)

Other databases:

- EMBL:   AE006914
- PIR:   F97714
- RefSeq:   NP_359755.1
- ProteinModelPortal:   Q92JE9
- GeneID:   928074
- GenomeReviews:   AE006914_GR
- KEGG:   rco:RC0118
- NMPDR:   fig|272944.1.peg.118
- OMA:   HPQRFDE
- ProtClustDB:   PRK05749
- BioCyc:   RCON272944:RC0118-MONOMER
- InterPro:   IPR007507
- InterPro:   IPR005728
- TIGRFAMs:   TIGR01045

Pfam domain/function: PF04413 Glycos_transf_N

EC number: 2.-.-.-

Molecular weight: Translated: 53047; Mature: 53047

Theoretical pI: Translated: 8.53; Mature: 8.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xbf9a348)-;

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMLLYYALSFILLPVYFIIILIRLLIGKEDIRRIQERFAIGKHRQDDSLDFMQTSANKEE
CCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCHHH
FKGDTSLRTTTYTLIREDEGLGSTYKLPLEASDARRLIWINAASIGESMVALTLIHNISK
HCCCCCCEEEEEEEEECCCCCCCEEEECCCCCCCCEEEEEEEHHHCHHHHHHHHHHHHHH
RYPDVRFLVTSWTNSSAKILTAKLPKIAVHQFLPIDNIIFTRKFLRNWQPDLGIFIESEL
HCCCEEEEEEECCCCCCEEEEECCCHHHHHHHCCCCHHHHHHHHHHCCCCCCCEEEECCC
WPCTINEGAKQCKLLLVNARISDKSFKAWLQRKSFFQLILKNCSKIIVQSERDLQKFNEL
CCEECCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHC
GVSDAVNLGNIKFANEKLPVNQEELSKLSLHLDNKRVVLFASTHPEDEEVILPIIKNLKE
CCCCCCCCCCEEECCCCCCCCHHHHHHHHEEECCCEEEEEECCCCCCCCCHHHHHHHHHH
QFLDCYIILIPRHPERVKSIIDNCKSHNLSATAKSQNDLPVLSDDLYIVDRFGEMGLFFS
HHCCEEEEEECCCHHHHHHHHHHHHCCCCEEECCCCCCCCEECCCEEEEECCCCCHHHHH
VATISFIGGSFKQGGHNILEAAYFSNCIIFGPDMSKNTDIAKGVLQNEAAIQIKNGEDLL
HHHHHHHCCCCCCCCHHHHHHHHHCCEEEECCCCCCCCHHHHHHHCCCCEEEEECCHHHH
TKLTYLLRSNNALELTTYRENALKFIKDNQKVLDEYLNVITKFL
HHHHHHHHCCCEEEEEEEHHHHHHHHHCCHHHHHHHHHHHHHCH
>Mature Secondary Structure
MMLLYYALSFILLPVYFIIILIRLLIGKEDIRRIQERFAIGKHRQDDSLDFMQTSANKEE
CCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCHHH
FKGDTSLRTTTYTLIREDEGLGSTYKLPLEASDARRLIWINAASIGESMVALTLIHNISK
HCCCCCCEEEEEEEEECCCCCCCEEEECCCCCCCCEEEEEEEHHHCHHHHHHHHHHHHHH
RYPDVRFLVTSWTNSSAKILTAKLPKIAVHQFLPIDNIIFTRKFLRNWQPDLGIFIESEL
HCCCEEEEEEECCCCCCEEEEECCCHHHHHHHCCCCHHHHHHHHHHCCCCCCCEEEECCC
WPCTINEGAKQCKLLLVNARISDKSFKAWLQRKSFFQLILKNCSKIIVQSERDLQKFNEL
CCEECCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHC
GVSDAVNLGNIKFANEKLPVNQEELSKLSLHLDNKRVVLFASTHPEDEEVILPIIKNLKE
CCCCCCCCCCEEECCCCCCCCHHHHHHHHEEECCCEEEEEECCCCCCCCCHHHHHHHHHH
QFLDCYIILIPRHPERVKSIIDNCKSHNLSATAKSQNDLPVLSDDLYIVDRFGEMGLFFS
HHCCEEEEEECCCHHHHHHHHHHHHCCCCEEECCCCCCCCEECCCEEEEECCCCCHHHHH
VATISFIGGSFKQGGHNILEAAYFSNCIIFGPDMSKNTDIAKGVLQNEAAIQIKNGEDLL
HHHHHHHCCCCCCCCHHHHHHHHHCCEEEECCCCCCCCHHHHHHHCCCCEEEEECCHHHH
TKLTYLLRSNNALELTTYRENALKFIKDNQKVLDEYLNVITKFL
HHHHHHHHCCCEEEEEEEHHHHHHHHHCCHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferring phosphorus-containing groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11557893