Click here to switch to the map view.

The map label for this gene is gltC [H]

Identifier: 158425525

GI number: 158425525

Start: 4453274

End: 4454188

Strand: Direct

Name: gltC [H]

Synonym: AZC_3901

Alternate gene names: 158425525

Gene position: 4453274-4454188 (Clockwise)

Preceding gene: 158425505

Following gene: 158425526

Centisome position: 82.93

GC content: 68.63

Gene sequence:

>915_bases
ATGCGGCATCTCAGATTCCTGCGCTACATGGACGAAGTGGCCCGCACCGGCTCCATCCGCGGGGCGGCCGCCCGGCTCAA
CGTCACGCCCTCGGCCCTTAACCGGCGCATCATGGATCTGGAGGAGGAACTGGGCCTCAAGCTGCTGGAGCGGCGGGCAC
GCGGCGTCAGCCTCACGGCGGCGGGCGAGGTGTTCGTGAGTTACATCCGCGAGCAACTCAATGATGCCGACCGCATGCGC
TCGCAACTGGAGGATCTGCGCGGGCTGCGGCGCGGCACCGTGCGCATCGCCTGCAGCCAGGCGCTGGCGCACGATTTTCT
CCCCCAGCAGATCGCCGCCTTTCGCCTGCGCTATCCGCTGATGACCTTCGAGGTGATGGTGGCCGACCACGAGCACGCCA
TCACCCTGCTGGTGGATTATGAGGTGGACCTCGTCCTCGTCTTTCGCCCGGCCTTCATCGGCCGCCTGCGCCCGCTCATG
ACCCTGCCGCAGCGGCTGGTGGCGTTGATGCCGGCGGACCATCCCCTCGCCCGCAAGCCGAAGCTGCGGCTCGCCGACTG
CACGGGCTATCCGCTGGCATTGTCCGAGCTCTCCACCGGAGGACGGCAGATGATCGAGGAGCGCTTGTCGCGCTCGGGCC
TGCGCTTCTCGGTGGCGGCGGAGGCCAATTCCTTCGAACTGCTGCGGGGGCTCGTGGTCCATTGCGGCATGATCTCGTTC
CAGATCGAGATCGGCGCGGAACCGGAAGCCATGCCGCCGGGTGTGGTTGTGCGCCCCGTGGACGAACGGGACCTGGCCGG
CGCCGATCTTGTGCTCGGCCAGTTGCGGGGCCGCAACCTGCCGCTCGCCGGCGCGCAGTTCGCCGAGCACCTCTCCGGCG
TGCTCCGCCAGCGCGCGGAAGCCTTGGCATCCTGA

Upstream 100 bases:

>100_bases
CTCCCGAACCCCGTGAGACTACGCACGGTGGAGTGATGCTATCTATTGCCGAATATTCCACGCATTGTAGCCCAAATGGC
TACAACCCGGTGGAGACGGC

Downstream 100 bases:

>100_bases
CACAGCGGATCGTGCGCGCCCCTCCCTTGCCCGCAAACAGCCCGGCGCAAAGCGCGAGCGGCTCTCTGCAGAAAAGTGCT
ACGGCACAAGGGATCGGCGT

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MRHLRFLRYMDEVARTGSIRGAAARLNVTPSALNRRIMDLEEELGLKLLERRARGVSLTAAGEVFVSYIREQLNDADRMR
SQLEDLRGLRRGTVRIACSQALAHDFLPQQIAAFRLRYPLMTFEVMVADHEHAITLLVDYEVDLVLVFRPAFIGRLRPLM
TLPQRLVALMPADHPLARKPKLRLADCTGYPLALSELSTGGRQMIEERLSRSGLRFSVAAEANSFELLRGLVVHCGMISF
QIEIGAEPEAMPPGVVVRPVDERDLAGADLVLGQLRGRNLPLAGAQFAEHLSGVLRQRAEALAS

Sequences:

>Translated_304_residues
MRHLRFLRYMDEVARTGSIRGAAARLNVTPSALNRRIMDLEEELGLKLLERRARGVSLTAAGEVFVSYIREQLNDADRMR
SQLEDLRGLRRGTVRIACSQALAHDFLPQQIAAFRLRYPLMTFEVMVADHEHAITLLVDYEVDLVLVFRPAFIGRLRPLM
TLPQRLVALMPADHPLARKPKLRLADCTGYPLALSELSTGGRQMIEERLSRSGLRFSVAAEANSFELLRGLVVHCGMISF
QIEIGAEPEAMPPGVVVRPVDERDLAGADLVLGQLRGRNLPLAGAQFAEHLSGVLRQRAEALAS
>Mature_304_residues
MRHLRFLRYMDEVARTGSIRGAAARLNVTPSALNRRIMDLEEELGLKLLERRARGVSLTAAGEVFVSYIREQLNDADRMR
SQLEDLRGLRRGTVRIACSQALAHDFLPQQIAAFRLRYPLMTFEVMVADHEHAITLLVDYEVDLVLVFRPAFIGRLRPLM
TLPQRLVALMPADHPLARKPKLRLADCTGYPLALSELSTGGRQMIEERLSRSGLRFSVAAEANSFELLRGLVVHCGMISF
QIEIGAEPEAMPPGVVVRPVDERDLAGADLVLGQLRGRNLPLAGAQFAEHLSGVLRQRAEALAS

Specific function: Positive regulator of glutamate biosynthesis (gltAB genes). Negatively regulates its own expression [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI157672245, Length=228, Percent_Identity=30.2631578947368, Blast_Score=101, Evalue=7e-23,
Organism=Escherichia coli, GI145693105, Length=256, Percent_Identity=28.515625, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1788748, Length=308, Percent_Identity=27.9220779220779, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1787879, Length=198, Percent_Identity=31.3131313131313, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1788481, Length=231, Percent_Identity=26.4069264069264, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1787601, Length=143, Percent_Identity=33.5664335664336, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788887, Length=191, Percent_Identity=32.4607329842932, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1787530, Length=239, Percent_Identity=24.2677824267782, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788296, Length=233, Percent_Identity=26.1802575107296, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1789204, Length=273, Percent_Identity=25.6410256410256, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1789639, Length=128, Percent_Identity=28.90625, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87081904, Length=240, Percent_Identity=25.4166666666667, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1786401, Length=160, Percent_Identity=30, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1789440, Length=138, Percent_Identity=30.4347826086957, Blast_Score=62, Evalue=6e-11,
Organism=Escherichia coli, GI1787128, Length=117, Percent_Identity=31.6239316239316, Blast_Score=62, Evalue=7e-11,
Organism=Escherichia coli, GI1790208, Length=147, Percent_Identity=29.9319727891156, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33864; Mature: 33864

Theoretical pI: Translated: 9.22; Mature: 9.22

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHLRFLRYMDEVARTGSIRGAAARLNVTPSALNRRIMDLEEELGLKLLERRARGVSLTA
CCHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEH
AGEVFVSYIREQLNDADRMRSQLEDLRGLRRGTVRIACSQALAHDFLPQQIAAFRLRYPL
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCH
MTFEVMVADHEHAITLLVDYEVDLVLVFRPAFIGRLRPLMTLPQRLVALMPADHPLARKP
HEEEEEEECCCCEEEEEEECCCCEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
KLRLADCTGYPLALSELSTGGRQMIEERLSRSGLRFSVAAEANSFELLRGLVVHCGMISF
CCEEECCCCCCHHHHHHCCCHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHCCEEEE
QIEIGAEPEAMPPGVVVRPVDERDLAGADLVLGQLRGRNLPLAGAQFAEHLSGVLRQRAE
EEEECCCCCCCCCCCEEECCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
ALAS
HHCC
>Mature Secondary Structure
MRHLRFLRYMDEVARTGSIRGAAARLNVTPSALNRRIMDLEEELGLKLLERRARGVSLTA
CCHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEH
AGEVFVSYIREQLNDADRMRSQLEDLRGLRRGTVRIACSQALAHDFLPQQIAAFRLRYPL
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCH
MTFEVMVADHEHAITLLVDYEVDLVLVFRPAFIGRLRPLMTLPQRLVALMPADHPLARKP
HEEEEEEECCCCEEEEEEECCCCEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
KLRLADCTGYPLALSELSTGGRQMIEERLSRSGLRFSVAAEANSFELLRGLVVHCGMISF
CCEEECCCCCCHHHHHHCCCHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHCCEEEE
QIEIGAEPEAMPPGVVVRPVDERDLAGADLVLGQLRGRNLPLAGAQFAEHLSGVLRQRAE
EEEECCCCCCCCCCCEEECCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
ALAS
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2548995; 9384377 [H]