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The map label for this gene is xapR [H]

Identifier: 158425501

GI number: 158425501

Start: 4428091

End: 4428987

Strand: Direct

Name: xapR [H]

Synonym: AZC_3877

Alternate gene names: 158425501

Gene position: 4428091-4428987 (Clockwise)

Preceding gene: 158425500

Following gene: 158425505

Centisome position: 82.46

GC content: 56.08

Gene sequence:

>897_bases
ATGCCGGATATATCTACCGGAACGCGCGTGTTGCGATATTTTATCGAGGTGGCTGGCCACAGCAGCTTTCGCAGGGCCGC
CATCTCGCTGGGCATCCAGGAATCATCGGTAAGCCGGGGCATTCGTAATCTTGAGCACCAGATCGGCGCCTCTCTCTTTA
TCAGACACTCGGGGGGCATAACGCTCACACCCGCGGGGCAACGCTTTCTTGATCGGGTGCGCGACGCACTCGATCAGCTT
GAAACCGGCGCTAGAGAAGCGGCTGCCACAGGGCAGCCGCAAAGAACTCACCTGAAAATCGGGGTATTTTCAGTTGCGGC
ATGCGGACCAATTTCGCAGCTGTTCGTCGATTTTGATCGTCACTACCCTCATATTGACGTTGAATTTCATGAATCATCAG
CGGCGCACCACCTACTATCCATTGGAAAGGCGGAAATTGATCTGGCGTTCACTGTTGGGAATTCGCATCCACATTCTTAT
GATGCAACCGAGATCTGGCGCGAGCGGGTGTTTTTCGCCTTTCGTGAGGGGCATCCATTGACGCTCAAAAGCCGCTTGGC
CTGGAGCGAGCTCGCTCAGGAACGCCTTCTAACGTCCTCCGGTGGTTCAGGTGATGAGATCCGCGATTACGTCACGGATC
GCGTAAGGGGCACGGGCGGCGAGCCGAAAGTGGTAGCGCATAACATTGGGCGTTACGGCCTATTGGGGCTGGTAGCGGCC
TGCCAGGGAATCATGCCCCTGCTGGAGTCGGAGACAATTCTTTCGATACCGGGAGTTACTTATCGACCCGTTGGCGGAGA
GGCGCTGCCGATCTTTGTAATAACCTCTCCTAAAAATGATAGCCCAGCCGCTCGTGCACTCCTAACTCTCGCTCGGACGA
GAGGTCAGTCGGGCTGA

Upstream 100 bases:

>100_bases
CCTCCTGGTGGCGTTCGTCATAGATGAGCTCTGGCAGGTGCACTTGATCGGCCGAACTCAGTCGACTGTCACGCTTTTAG
TTTGACGGACAAATTAGGAT

Downstream 100 bases:

>100_bases
TCGCACCGTGGACCATGCGCGTATCGCTTCGGCCTGGCCGCCGCGACCTTGCGAATGCCCTATCTTCGGCATATCGGCCT
CCATGGGGATCGAGACCAAG

Product: hypothetical protein

Products: NA

Alternate protein names: Xanthosine operon regulatory protein [H]

Number of amino acids: Translated: 298; Mature: 297

Protein sequence:

>298_residues
MPDISTGTRVLRYFIEVAGHSSFRRAAISLGIQESSVSRGIRNLEHQIGASLFIRHSGGITLTPAGQRFLDRVRDALDQL
ETGAREAAATGQPQRTHLKIGVFSVAACGPISQLFVDFDRHYPHIDVEFHESSAAHHLLSIGKAEIDLAFTVGNSHPHSY
DATEIWRERVFFAFREGHPLTLKSRLAWSELAQERLLTSSGGSGDEIRDYVTDRVRGTGGEPKVVAHNIGRYGLLGLVAA
CQGIMPLLESETILSIPGVTYRPVGGEALPIFVITSPKNDSPAARALLTLARTRGQSG

Sequences:

>Translated_298_residues
MPDISTGTRVLRYFIEVAGHSSFRRAAISLGIQESSVSRGIRNLEHQIGASLFIRHSGGITLTPAGQRFLDRVRDALDQL
ETGAREAAATGQPQRTHLKIGVFSVAACGPISQLFVDFDRHYPHIDVEFHESSAAHHLLSIGKAEIDLAFTVGNSHPHSY
DATEIWRERVFFAFREGHPLTLKSRLAWSELAQERLLTSSGGSGDEIRDYVTDRVRGTGGEPKVVAHNIGRYGLLGLVAA
CQGIMPLLESETILSIPGVTYRPVGGEALPIFVITSPKNDSPAARALLTLARTRGQSG
>Mature_297_residues
PDISTGTRVLRYFIEVAGHSSFRRAAISLGIQESSVSRGIRNLEHQIGASLFIRHSGGITLTPAGQRFLDRVRDALDQLE
TGAREAAATGQPQRTHLKIGVFSVAACGPISQLFVDFDRHYPHIDVEFHESSAAHHLLSIGKAEIDLAFTVGNSHPHSYD
ATEIWRERVFFAFREGHPLTLKSRLAWSELAQERLLTSSGGSGDEIRDYVTDRVRGTGGEPKVVAHNIGRYGLLGLVAAC
QGIMPLLESETILSIPGVTYRPVGGEALPIFVITSPKNDSPAARALLTLARTRGQSG

Specific function: Positive regulator required for the expression of xapA and xapB. Binds to the inducer xanthosine [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI2367136, Length=286, Percent_Identity=25.8741258741259, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1787879, Length=287, Percent_Identity=27.8745644599303, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI157672245, Length=218, Percent_Identity=28.8990825688073, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI145693105, Length=197, Percent_Identity=25.3807106598985, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790399, Length=260, Percent_Identity=23.8461538461538, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1788887, Length=288, Percent_Identity=22.9166666666667, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1788748, Length=292, Percent_Identity=25.3424657534247, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787806, Length=249, Percent_Identity=25.7028112449799, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787601, Length=172, Percent_Identity=28.4883720930233, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1787128, Length=116, Percent_Identity=35.3448275862069, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1790262, Length=176, Percent_Identity=24.4318181818182, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1787530, Length=259, Percent_Identity=25.0965250965251, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1786401, Length=144, Percent_Identity=28.4722222222222, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32382; Mature: 32251

Theoretical pI: Translated: 7.85; Mature: 7.85

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDISTGTRVLRYFIEVAGHSSFRRAAISLGIQESSVSRGIRNLEHQIGASLFIRHSGGI
CCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCEEEEEECCCE
TLTPAGQRFLDRVRDALDQLETGAREAAATGQPQRTHLKIGVFSVAACGPISQLFVDFDR
EECCCHHHHHHHHHHHHHHHHHCHHHHHCCCCCCCEEEEEEEEEHHCCCHHHHHHHHHHC
HYPHIDVEFHESSAAHHLLSIGKAEIDLAFTVGNSHPHSYDATEIWRERVFFAFREGHPL
CCCEEEEEECCCHHHHHHHHCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCE
TLKSRLAWSELAQERLLTSSGGSGDEIRDYVTDRVRGTGGEPKVVAHNIGRYGLLGLVAA
EHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHH
CQGIMPLLESETILSIPGVTYRPVGGEALPIFVITSPKNDSPAARALLTLARTRGQSG
HHHHHHHHCCCCEEECCCCEEECCCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PDISTGTRVLRYFIEVAGHSSFRRAAISLGIQESSVSRGIRNLEHQIGASLFIRHSGGI
CCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCEEEEEECCCE
TLTPAGQRFLDRVRDALDQLETGAREAAATGQPQRTHLKIGVFSVAACGPISQLFVDFDR
EECCCHHHHHHHHHHHHHHHHHCHHHHHCCCCCCCEEEEEEEEEHHCCCHHHHHHHHHHC
HYPHIDVEFHESSAAHHLLSIGKAEIDLAFTVGNSHPHSYDATEIWRERVFFAFREGHPL
CCCEEEEEECCCHHHHHHHHCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCE
TLKSRLAWSELAQERLLTSSGGSGDEIRDYVTDRVRGTGGEPKVVAHNIGRYGLLGLVAA
EHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHH
CQGIMPLLESETILSIPGVTYRPVGGEALPIFVITSPKNDSPAARALLTLARTRGQSG
HHHHHHHHCCCCEEECCCCEEECCCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2201776; 9205837; 9278503; 7559336 [H]