Click here to switch to the map view.

The map label for this gene is sdaA [H]

Identifier: 158425500

GI number: 158425500

Start: 4426480

End: 4427862

Strand: Direct

Name: sdaA [H]

Synonym: AZC_3876

Alternate gene names: 158425500

Gene position: 4426480-4427862 (Clockwise)

Preceding gene: 158425499

Following gene: 158425501

Centisome position: 82.43

GC content: 67.32

Gene sequence:

>1383_bases
ATGTTTCTCAGCGTGTTCGACATCTTCAAAGTGGGGATCGGCCCGTCTTCGTCCCACACCATGGGGCCGATGACCGCCGC
GGCGCGCTTCCTCGACCTGTTGCGGCGGTTGCCCTTCAGCGGCCGGGCGGCCCGCCTGAGGGTGACCTTGCACGGCTCGC
TGGCCTTCACCGGAAAGGGCCATGGCACGGATCGCGCGGTGGCTCTTGGCCTTCTGGGCTGGCTTCCGGCGACATTGGAT
CCCGACGAAGCTGAGCGCCAACTCACAAGGCTGCGGGACACCTGCACCTTAAGTCCGCCTGGGTTGCCCCCCTTGGCCTT
CGACCCGGCGGCCGACATCGTGTTCGACTTCGGGCCGCCTTTGCCCGGCCATGCCAACGGCCTCATCCTTGCCGCGCTCC
ATGCGGACGGCGGGATGCTCCTGACCGAGACCTATTATTCCATCGGCGGCGGGTTCGTCGTCACGGCCGCGGAGCTGGAT
CTGCCCGGAGCGGACACGGCCGTCGCCGCGCCATATCCCTTTCCCTTCAGAAACGCCGCCGAGATGCTGCGCATGGCGCG
GGACTGCGGGCGCTCCATCGCGGCCATGAAGCGGGAGAATGAAATCCGCCTGCGTCCGGAGGCGGAGGTCGAAGTGGGCG
TGGCCGGCCTCTGGTCGGTCATGAACGGCTGTATTGAGCGTGGCCTCAGTCAGTCCGGCGACTTGCCCGGCGGCTTGCGT
GTGCGCCGCCGCGCCCGCAGCATCCACCAGCAATTGCTGGCGGAGCGGGCGTCAAATTCCAGCCAGCCTCATGCGGGCTC
GGACTGGCTGAGCGTCTATGCCATGGCCGTGAACGAGGAAAACGCCGCGGGCGGCAAGGTGGTCACGGCGCCCACCAATG
GCGCGGCCGGCGTCGTCCCCGCCGTGCTGCGCTATTATCTCGACCACTGTCGCGGGGCGGACCCCGCCCTTATTTCGGAT
TTCCTGCTGACGGCCGCCGCCATCGGCGGCTTGATTAAGCACAATGCCTCCATCTCCGGCGCCGAAGCCGGCTGCCAGGG
CGAGGTCGGCTCGGCGGCCGCCATGGCCGCGGCGGGCCTCTGCGCGGTGCTGGGTGGCACGCCGGGGCAGGTGGAGAATG
CCGCCGAAATTGCCCTGGAGCATCATCTGGGCATGACCTGCGACCCGGTTGCCGGCCTGGTTCAGGTGCCGTGCATTGAG
CGCAACGGCATCGGCGCCACCAAAGCAGTGGCCGCCGCCTCCCTCGCCCTGCGGGGCGATGGAACCCACTTTATACCGCT
GGACAATTGCATCGAAGCCATGCGCCAGACCGGCGAAGAGATGAGCACCAAATTCAAGGAAACCAGCCTCGGCGGCTTGG
CAGTCAATCTGCCGGAATGCTGA

Upstream 100 bases:

>100_bases
CCGCCGGCTCAATGTTTCACATCTCCGAAGAGCCCGCGCCTGAAGGCCTTTCTCCAGGCTGTGGTGCATTGAACCAGGCG
GAGACGTAGCGGGAGGCCCC

Downstream 100 bases:

>100_bases
ATAGCTGCTTCGACTGTATTAGTGACCGCGGAAGAGCCTTTCTTCGAAGAAGCAATTGGACGTTTTGCTTCACCCAGACT
CTCTGACCAAGCGCCAGAAG

Product: L-serine dehydratase 1

Products: NA

Alternate protein names: SDH; L-serine deaminase; L-SD [H]

Number of amino acids: Translated: 460; Mature: 460

Protein sequence:

>460_residues
MFLSVFDIFKVGIGPSSSHTMGPMTAAARFLDLLRRLPFSGRAARLRVTLHGSLAFTGKGHGTDRAVALGLLGWLPATLD
PDEAERQLTRLRDTCTLSPPGLPPLAFDPAADIVFDFGPPLPGHANGLILAALHADGGMLLTETYYSIGGGFVVTAAELD
LPGADTAVAAPYPFPFRNAAEMLRMARDCGRSIAAMKRENEIRLRPEAEVEVGVAGLWSVMNGCIERGLSQSGDLPGGLR
VRRRARSIHQQLLAERASNSSQPHAGSDWLSVYAMAVNEENAAGGKVVTAPTNGAAGVVPAVLRYYLDHCRGADPALISD
FLLTAAAIGGLIKHNASISGAEAGCQGEVGSAAAMAAAGLCAVLGGTPGQVENAAEIALEHHLGMTCDPVAGLVQVPCIE
RNGIGATKAVAAASLALRGDGTHFIPLDNCIEAMRQTGEEMSTKFKETSLGGLAVNLPEC

Sequences:

>Translated_460_residues
MFLSVFDIFKVGIGPSSSHTMGPMTAAARFLDLLRRLPFSGRAARLRVTLHGSLAFTGKGHGTDRAVALGLLGWLPATLD
PDEAERQLTRLRDTCTLSPPGLPPLAFDPAADIVFDFGPPLPGHANGLILAALHADGGMLLTETYYSIGGGFVVTAAELD
LPGADTAVAAPYPFPFRNAAEMLRMARDCGRSIAAMKRENEIRLRPEAEVEVGVAGLWSVMNGCIERGLSQSGDLPGGLR
VRRRARSIHQQLLAERASNSSQPHAGSDWLSVYAMAVNEENAAGGKVVTAPTNGAAGVVPAVLRYYLDHCRGADPALISD
FLLTAAAIGGLIKHNASISGAEAGCQGEVGSAAAMAAAGLCAVLGGTPGQVENAAEIALEHHLGMTCDPVAGLVQVPCIE
RNGIGATKAVAAASLALRGDGTHFIPLDNCIEAMRQTGEEMSTKFKETSLGGLAVNLPEC
>Mature_460_residues
MFLSVFDIFKVGIGPSSSHTMGPMTAAARFLDLLRRLPFSGRAARLRVTLHGSLAFTGKGHGTDRAVALGLLGWLPATLD
PDEAERQLTRLRDTCTLSPPGLPPLAFDPAADIVFDFGPPLPGHANGLILAALHADGGMLLTETYYSIGGGFVVTAAELD
LPGADTAVAAPYPFPFRNAAEMLRMARDCGRSIAAMKRENEIRLRPEAEVEVGVAGLWSVMNGCIERGLSQSGDLPGGLR
VRRRARSIHQQLLAERASNSSQPHAGSDWLSVYAMAVNEENAAGGKVVTAPTNGAAGVVPAVLRYYLDHCRGADPALISD
FLLTAAAIGGLIKHNASISGAEAGCQGEVGSAAAMAAAGLCAVLGGTPGQVENAAEIALEHHLGMTCDPVAGLVQVPCIE
RNGIGATKAVAAASLALRGDGTHFIPLDNCIEAMRQTGEEMSTKFKETSLGGLAVNLPEC

Specific function: Deaminates Also Threonine, Particularly When It Is Present In High Concentration. [C]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI1789161, Length=463, Percent_Identity=47.0842332613391, Blast_Score=398, Evalue=1e-112,
Organism=Escherichia coli, GI48994925, Length=457, Percent_Identity=47.9212253829322, Blast_Score=394, Evalue=1e-111,
Organism=Escherichia coli, GI1788116, Length=457, Percent_Identity=46.6083150984683, Blast_Score=393, Evalue=1e-110,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004644
- InterPro:   IPR005130
- InterPro:   IPR005131 [H]

Pfam domain/function: PF03313 SDH_alpha; PF03315 SDH_beta [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 47829; Mature: 47829

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLSVFDIFKVGIGPSSSHTMGPMTAAARFLDLLRRLPFSGRAARLRVTLHGSLAFTGKG
CEEEHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEEEEEECCC
HGTDRAVALGLLGWLPATLDPDEAERQLTRLRDTCTLSPPGLPPLAFDPAADIVFDFGPP
CCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHEEEECCCC
LPGHANGLILAALHADGGMLLTETYYSIGGGFVVTAAELDLPGADTAVAAPYPFPFRNAA
CCCCCCCEEEEEEECCCCEEEEHHHHHCCCCEEEEEEEECCCCCCCCEECCCCCCCHHHH
EMLRMARDCGRSIAAMKRENEIRLRPEAEVEVGVAGLWSVMNGCIERGLSQSGDLPGGLR
HHHHHHHHHHHHHHHHHCCCCEEECCCCCEEHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
VRRRARSIHQQLLAERASNSSQPHAGSDWLSVYAMAVNEENAAGGKVVTAPTNGAAGVVP
HHHHHHHHHHHHHHHHHCCCCCCCCCCHHHEEEEEEECCCCCCCCEEEECCCCCCCHHHH
AVLRYYLDHCRGADPALISDFLLTAAAIGGLIKHNASISGAEAGCQGEVGSAAAMAAAGL
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHH
CAVLGGTPGQVENAAEIALEHHLGMTCDPVAGLVQVPCIERNGIGATKAVAAASLALRGD
HHHHCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHEEECC
GTHFIPLDNCIEAMRQTGEEMSTKFKETSLGGLAVNLPEC
CCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCC
>Mature Secondary Structure
MFLSVFDIFKVGIGPSSSHTMGPMTAAARFLDLLRRLPFSGRAARLRVTLHGSLAFTGKG
CEEEHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEEEEEECCC
HGTDRAVALGLLGWLPATLDPDEAERQLTRLRDTCTLSPPGLPPLAFDPAADIVFDFGPP
CCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHEEEECCCC
LPGHANGLILAALHADGGMLLTETYYSIGGGFVVTAAELDLPGADTAVAAPYPFPFRNAA
CCCCCCCEEEEEEECCCCEEEEHHHHHCCCCEEEEEEEECCCCCCCCEECCCCCCCHHHH
EMLRMARDCGRSIAAMKRENEIRLRPEAEVEVGVAGLWSVMNGCIERGLSQSGDLPGGLR
HHHHHHHHHHHHHHHHHCCCCEEECCCCCEEHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
VRRRARSIHQQLLAERASNSSQPHAGSDWLSVYAMAVNEENAAGGKVVTAPTNGAAGVVP
HHHHHHHHHHHHHHHHHCCCCCCCCCCHHHEEEEEEECCCCCCCCEEEECCCCCCCHHHH
AVLRYYLDHCRGADPALISDFLLTAAAIGGLIKHNASISGAEAGCQGEVGSAAAMAAAGL
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHH
CAVLGGTPGQVENAAEIALEHHLGMTCDPVAGLVQVPCIERNGIGATKAVAAASLALRGD
HHHHCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHEEECC
GTHFIPLDNCIEAMRQTGEEMSTKFKETSLGGLAVNLPEC
CCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]