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The map label for this gene is oatA [H]

Identifier: 158425140

GI number: 158425140

Start: 4035614

End: 4037581

Strand: Reverse

Name: oatA [H]

Synonym: AZC_3516

Alternate gene names: 158425140

Gene position: 4037581-4035614 (Counterclockwise)

Preceding gene: 158425141

Following gene: 158425139

Centisome position: 75.19

GC content: 68.45

Gene sequence:

>1968_bases
GTGGGGATCCTCTTAGGCATCATGAAGTATCGGTCGGATATCAGCGGCCTCCGCGCGCTCGCGGTGGTGCCGGTCGTCGT
TTTCCATTTCAACGAGGCGTGGCTTCCCGGCGGCTTTGTCGGCGTCGACATCTTCTTCGTCATCTCCGGTTACCTCATCA
CGGCGATCCTCGCCGGTGATCTGGCGCAGGGCCGCTTCAGCCTGCTGCGCTTCTATGATCGCCGCCTGCGCCGCATCGTG
CCGGCCTTCGCCGCCGTCGCGCTGGTGACCGCGCTCGTCAGCCTCTTCATCCTGCCGCCGGTGCTGCTGAGCGGTTTCGG
CGCCTCGCTGCGGGCCGCCTCCATCTTCTTCGCCAACCGCTATTTCCTCTCGGTGACGCACTATTTCGGCGCGGCGCCGG
ACGAGGTGTTCCTGCTGCACACCTGGTCGCTGTCGGTGGAGGAGCAGTTCTATCTCGGCTGGCCGCTGCTGCTGGCCGCC
CTGTTCCACCCGCGGCTCAAGCGCTGGCTGCCCCATATCGTCGGGACGCTGATCCTCGTCTCCCTCTTCGTCGCCACCCG
CAATGCGGTGCAGCGGCCGGTGACGGCCTTCTACAATTCCAACGGCCGCTTCTGGGAACTGATGCTGGGCGCCTGGCTCG
CGCTCGGCTACGTGCCGCGCCTGAACCGGATCTGGGCGGAAGTGGCGGCGGCCGTGGGCCTTGCGCTCATCGTCGCAACG
CTGGTGTTGTTTGATCCCAGCCGCATCATCTTTCCCGGCCTCAGCGCGCTCGTGCCGACGCTGGGTGCAGCCCTGCTGCT
GTGGTCGGGCGAGGAGGGGCGGCGGACGCTGGTGGGGCGTATCCTCTCCTTCGCGCCCATCGCCGGCATCGGGCTCATCT
CCTACTCGCTCTATCTGTGGCACTGGCCCATCATCGCCATCCATCGCTATCTCACCTTCCGGACCCCGACGCCGCTCGAA
TGCGTGCTGCTGTTCGCGGTGATGATCGCCGTCTCGGCCTTCTCCTGGCGCTTCATCGAAAACCCGTTCCGCCACACGGT
GCGCGTGCCGACCCGCCGGATGGAATGGCGCGGCGTCGCGACCGGTGTCGCGATGCTGGCGCTGCTGGTCGGCATCGGCA
CGCTCTTCACGGCCACCGGCGGGCTGCCGGCGCGGGCGACGGCCGGCTTCCTGAAGTCCGAAGCCATCGTGAACACCTTC
TGGCGGGGCCGCGAAGCCTGCCTTCTGGGACGCACGAGCGACCGCGAGCGGGACTGCCGTTTCGGCGCCTCGGCGCCCGA
CGCACCGCTCTTCGTCCTGTGGGGGGATTCTCAGGCAGACCAGCACGGGCCGGGCCTCGATCGGGTGGCGCGCGAGGTGG
GCATGAGCTTCCTCCAACTCACCCGTACAGGCTGCGCGCCGCTGGCCCCGGAGACCGGCGGGGGCGCCCTACAGAGCCGC
GAGACGATCGACTGCAATGCCTTTCGTGCCGAGGCGCTGAAGCGGATCATCGAGGATCCCAAGGTCCGCTTCGCCGTCAT
CGCCGGCCGCTGGACCAATGAGCCCGCCCTCGGCCCGGCCATGGCGCGCCTGAAAGCGGCCGTGGACCAGATCACCGCCG
CCGGCAAGCCGGTGCTGCTCGCCGCCCCCATCGGCGCCTTTGCCAATGGCGGCGGCCGCTGCATCGTGCGGCGCGGCTTC
ATGGGTCTCGACGACGCCATGTGCGGCCTCTCCCGCATCACCTCCGACGCGCAGGCGCAGCCGACCGAGGATGCCTTGCG
CGCCATTGCGGCAAACACGCCCGGCGTGACGCTCTTTGTGCCTCGTCCGCTGTTCTGCGACGAGACGGCGTGCCATCCCC
GCAAGGATGACGTGCCGCTCTATTTCGACGGTGATCATCTGAATGTGGAGGGATCGCTGTTCCTGGCGCCGGCCTGGAGG
AGCGCGTTGGAGAAGGCCGCGGCGGCGGTATCCCGTCCGGGGTCGTGA

Upstream 100 bases:

>100_bases
CACGCCGGCGGCGCAAAATGCGGCGCGCGGCGCGGCCGCCCCCGAAAGTGCCGCCCCGGTGGTGGCCATGGGCAGCACAT
CCCGCTAGGGTCCGCCCCGT

Downstream 100 bases:

>100_bases
GGCTCGGCGGCAATCACAGATGTTGGCGTTTTTCGTCTTCCCTCATCGGTTGTCGAAAAATGCATGAGCCGGCGCCGCAG
ATGCATCTCGTGAGTTGATC

Product: O-antigen acetylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 655; Mature: 654

Protein sequence:

>655_residues
MGILLGIMKYRSDISGLRALAVVPVVVFHFNEAWLPGGFVGVDIFFVISGYLITAILAGDLAQGRFSLLRFYDRRLRRIV
PAFAAVALVTALVSLFILPPVLLSGFGASLRAASIFFANRYFLSVTHYFGAAPDEVFLLHTWSLSVEEQFYLGWPLLLAA
LFHPRLKRWLPHIVGTLILVSLFVATRNAVQRPVTAFYNSNGRFWELMLGAWLALGYVPRLNRIWAEVAAAVGLALIVAT
LVLFDPSRIIFPGLSALVPTLGAALLLWSGEEGRRTLVGRILSFAPIAGIGLISYSLYLWHWPIIAIHRYLTFRTPTPLE
CVLLFAVMIAVSAFSWRFIENPFRHTVRVPTRRMEWRGVATGVAMLALLVGIGTLFTATGGLPARATAGFLKSEAIVNTF
WRGREACLLGRTSDRERDCRFGASAPDAPLFVLWGDSQADQHGPGLDRVAREVGMSFLQLTRTGCAPLAPETGGGALQSR
ETIDCNAFRAEALKRIIEDPKVRFAVIAGRWTNEPALGPAMARLKAAVDQITAAGKPVLLAAPIGAFANGGGRCIVRRGF
MGLDDAMCGLSRITSDAQAQPTEDALRAIAANTPGVTLFVPRPLFCDETACHPRKDDVPLYFDGDHLNVEGSLFLAPAWR
SALEKAAAAVSRPGS

Sequences:

>Translated_655_residues
MGILLGIMKYRSDISGLRALAVVPVVVFHFNEAWLPGGFVGVDIFFVISGYLITAILAGDLAQGRFSLLRFYDRRLRRIV
PAFAAVALVTALVSLFILPPVLLSGFGASLRAASIFFANRYFLSVTHYFGAAPDEVFLLHTWSLSVEEQFYLGWPLLLAA
LFHPRLKRWLPHIVGTLILVSLFVATRNAVQRPVTAFYNSNGRFWELMLGAWLALGYVPRLNRIWAEVAAAVGLALIVAT
LVLFDPSRIIFPGLSALVPTLGAALLLWSGEEGRRTLVGRILSFAPIAGIGLISYSLYLWHWPIIAIHRYLTFRTPTPLE
CVLLFAVMIAVSAFSWRFIENPFRHTVRVPTRRMEWRGVATGVAMLALLVGIGTLFTATGGLPARATAGFLKSEAIVNTF
WRGREACLLGRTSDRERDCRFGASAPDAPLFVLWGDSQADQHGPGLDRVAREVGMSFLQLTRTGCAPLAPETGGGALQSR
ETIDCNAFRAEALKRIIEDPKVRFAVIAGRWTNEPALGPAMARLKAAVDQITAAGKPVLLAAPIGAFANGGGRCIVRRGF
MGLDDAMCGLSRITSDAQAQPTEDALRAIAANTPGVTLFVPRPLFCDETACHPRKDDVPLYFDGDHLNVEGSLFLAPAWR
SALEKAAAAVSRPGS
>Mature_654_residues
GILLGIMKYRSDISGLRALAVVPVVVFHFNEAWLPGGFVGVDIFFVISGYLITAILAGDLAQGRFSLLRFYDRRLRRIVP
AFAAVALVTALVSLFILPPVLLSGFGASLRAASIFFANRYFLSVTHYFGAAPDEVFLLHTWSLSVEEQFYLGWPLLLAAL
FHPRLKRWLPHIVGTLILVSLFVATRNAVQRPVTAFYNSNGRFWELMLGAWLALGYVPRLNRIWAEVAAAVGLALIVATL
VLFDPSRIIFPGLSALVPTLGAALLLWSGEEGRRTLVGRILSFAPIAGIGLISYSLYLWHWPIIAIHRYLTFRTPTPLEC
VLLFAVMIAVSAFSWRFIENPFRHTVRVPTRRMEWRGVATGVAMLALLVGIGTLFTATGGLPARATAGFLKSEAIVNTFW
RGREACLLGRTSDRERDCRFGASAPDAPLFVLWGDSQADQHGPGLDRVAREVGMSFLQLTRTGCAPLAPETGGGALQSRE
TIDCNAFRAEALKRIIEDPKVRFAVIAGRWTNEPALGPAMARLKAAVDQITAAGKPVLLAAPIGAFANGGGRCIVRRGFM
GLDDAMCGLSRITSDAQAQPTEDALRAIAANTPGVTLFVPRPLFCDETACHPRKDDVPLYFDGDHLNVEGSLFLAPAWRS
ALEKAAAAVSRPGS

Specific function: Responsible for O-acetylation at the C(6)-hydroxyl group of N-acetylmuramyl residues, forming the corresponding N,6-O- diacetylmuramic acid of the peptidoglycan. O-acetylation of the peptidoglycan is the major determinant for lysozyme resistance [H]

COG id: COG1835

COG function: function code I; Predicted acyltransferases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyltransferase 3 family [H]

Homologues:

Organism=Caenorhabditis elegans, GI17507733, Length=544, Percent_Identity=26.6544117647059, Blast_Score=124, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17507283, Length=350, Percent_Identity=30.2857142857143, Blast_Score=115, Evalue=7e-26,
Organism=Caenorhabditis elegans, GI17541014, Length=512, Percent_Identity=25.390625, Blast_Score=114, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17507735, Length=333, Percent_Identity=29.1291291291291, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17541016, Length=371, Percent_Identity=28.3018867924528, Blast_Score=112, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI17541412, Length=534, Percent_Identity=25.6554307116105, Blast_Score=112, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI17532481, Length=560, Percent_Identity=24.8214285714286, Blast_Score=112, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI17507287, Length=341, Percent_Identity=30.4985337243402, Blast_Score=109, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17559158, Length=528, Percent_Identity=24.0530303030303, Blast_Score=107, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17541414, Length=365, Percent_Identity=29.8630136986301, Blast_Score=107, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17507167, Length=355, Percent_Identity=28.169014084507, Blast_Score=106, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17506687, Length=497, Percent_Identity=26.1569416498994, Blast_Score=105, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17542538, Length=537, Percent_Identity=23.8361266294227, Blast_Score=103, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI193203179, Length=494, Percent_Identity=26.9230769230769, Blast_Score=103, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI212640769, Length=356, Percent_Identity=28.3707865168539, Blast_Score=101, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17539118, Length=353, Percent_Identity=29.4617563739377, Blast_Score=99, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI17509001, Length=523, Percent_Identity=26.0038240917782, Blast_Score=99, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI17540232, Length=537, Percent_Identity=26.0707635009311, Blast_Score=98, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI193208811, Length=335, Percent_Identity=27.4626865671642, Blast_Score=98, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI86562056, Length=336, Percent_Identity=29.1666666666667, Blast_Score=96, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17507299, Length=348, Percent_Identity=30.4597701149425, Blast_Score=95, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17507289, Length=348, Percent_Identity=30.4597701149425, Blast_Score=95, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71984481, Length=336, Percent_Identity=27.6785714285714, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI115534354, Length=332, Percent_Identity=28.6144578313253, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI193203181, Length=309, Percent_Identity=30.7443365695793, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17562856, Length=325, Percent_Identity=29.8461538461538, Blast_Score=93, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17562864, Length=336, Percent_Identity=31.547619047619, Blast_Score=92, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17562866, Length=387, Percent_Identity=28.1653746770026, Blast_Score=92, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71988046, Length=335, Percent_Identity=29.5522388059701, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17560876, Length=353, Percent_Identity=27.7620396600567, Blast_Score=91, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI71990417, Length=354, Percent_Identity=27.9661016949153, Blast_Score=90, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI71983744, Length=325, Percent_Identity=28.6153846153846, Blast_Score=90, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI212646204, Length=355, Percent_Identity=25.9154929577465, Blast_Score=89, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17542762, Length=362, Percent_Identity=26.5193370165746, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17543924, Length=323, Percent_Identity=29.4117647058824, Blast_Score=87, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI133903927, Length=333, Percent_Identity=25.8258258258258, Blast_Score=85, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17559544, Length=361, Percent_Identity=29.6398891966759, Blast_Score=85, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI193208625, Length=359, Percent_Identity=25.0696378830084, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI32567150, Length=177, Percent_Identity=33.3333333333333, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71982248, Length=344, Percent_Identity=30.8139534883721, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17531875, Length=340, Percent_Identity=27.0588235294118, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17564132, Length=73, Percent_Identity=43.8356164383562, Blast_Score=69, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI212642133, Length=353, Percent_Identity=25.7790368271955, Blast_Score=67, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI193206646, Length=300, Percent_Identity=27.6666666666667, Blast_Score=65, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002656
- InterPro:   IPR013830
- InterPro:   IPR013831 [H]

Pfam domain/function: PF01757 Acyl_transf_3 [H]

EC number: NA

Molecular weight: Translated: 71295; Mature: 71164

Theoretical pI: Translated: 9.86; Mature: 9.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGILLGIMKYRSDISGLRALAVVPVVVFHFNEAWLPGGFVGVDIFFVISGYLITAILAGD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LAQGRFSLLRFYDRRLRRIVPAFAAVALVTALVSLFILPPVLLSGFGASLRAASIFFANR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
YFLSVTHYFGAAPDEVFLLHTWSLSVEEQFYLGWPLLLAALFHPRLKRWLPHIVGTLILV
HHEEHHHHHCCCCCCEEEEEEEECCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLFVATRNAVQRPVTAFYNSNGRFWELMLGAWLALGYVPRLNRIWAEVAAAVGLALIVAT
HHHHHHHHHHHCCHHHEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVLFDPSRIIFPGLSALVPTLGAALLLWSGEEGRRTLVGRILSFAPIAGIGLISYSLYLW
HHHHCCCHHHHCCHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
HWPIIAIHRYLTFRTPTPLECVLLFAVMIAVSAFSWRFIENPFRHTVRVPTRRMEWRGVA
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHEECCCHHHHHHHHH
TGVAMLALLVGIGTLFTATGGLPARATAGFLKSEAIVNTFWRGREACLLGRTSDRERDCR
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCC
FGASAPDAPLFVLWGDSQADQHGPGLDRVAREVGMSFLQLTRTGCAPLAPETGGGALQSR
CCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
ETIDCNAFRAEALKRIIEDPKVRFAVIAGRWTNEPALGPAMARLKAAVDQITAAGKPVLL
CCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEE
AAPIGAFANGGGRCIVRRGFMGLDDAMCGLSRITSDAQAQPTEDALRAIAANTPGVTLFV
EECCCHHCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCEEEEE
PRPLFCDETACHPRKDDVPLYFDGDHLNVEGSLFLAPAWRSALEKAAAAVSRPGS
CCCCCCCCCCCCCCCCCCCEEECCCEEEECCCEEECHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
GILLGIMKYRSDISGLRALAVVPVVVFHFNEAWLPGGFVGVDIFFVISGYLITAILAGD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LAQGRFSLLRFYDRRLRRIVPAFAAVALVTALVSLFILPPVLLSGFGASLRAASIFFANR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
YFLSVTHYFGAAPDEVFLLHTWSLSVEEQFYLGWPLLLAALFHPRLKRWLPHIVGTLILV
HHEEHHHHHCCCCCCEEEEEEEECCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLFVATRNAVQRPVTAFYNSNGRFWELMLGAWLALGYVPRLNRIWAEVAAAVGLALIVAT
HHHHHHHHHHHCCHHHEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVLFDPSRIIFPGLSALVPTLGAALLLWSGEEGRRTLVGRILSFAPIAGIGLISYSLYLW
HHHHCCCHHHHCCHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
HWPIIAIHRYLTFRTPTPLECVLLFAVMIAVSAFSWRFIENPFRHTVRVPTRRMEWRGVA
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHEECCCHHHHHHHHH
TGVAMLALLVGIGTLFTATGGLPARATAGFLKSEAIVNTFWRGREACLLGRTSDRERDCR
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCC
FGASAPDAPLFVLWGDSQADQHGPGLDRVAREVGMSFLQLTRTGCAPLAPETGGGALQSR
CCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
ETIDCNAFRAEALKRIIEDPKVRFAVIAGRWTNEPALGPAMARLKAAVDQITAAGKPVLL
CCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEE
AAPIGAFANGGGRCIVRRGFMGLDDAMCGLSRITSDAQAQPTEDALRAIAANTPGVTLFV
EECCCHHCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCEEEEE
PRPLFCDETACHPRKDDVPLYFDGDHLNVEGSLFLAPAWRSALEKAAAAVSRPGS
CCCCCCCCCCCCCCCCCCCEEECCCEEEECCCEEECHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA