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The map label for this gene is wecB [H]

Identifier: 158424839

GI number: 158424839

Start: 3680330

End: 3681496

Strand: Direct

Name: wecB [H]

Synonym: AZC_3215

Alternate gene names: 158424839

Gene position: 3680330-3681496 (Clockwise)

Preceding gene: 158424837

Following gene: 158424840

Centisome position: 68.54

GC content: 65.9

Gene sequence:

>1167_bases
ATGAAGGTGATGAGCATATTCGGGACGCGGCCTGAAGCCATCAAGATGGCGCCGCTCGTCCGAGCCATCGAGGCGTCTGC
GGATCTGTCGGGACTGGTGTGCGTGACGGGACAGCATCGCGCGATGCTGGATCAGGTGCTGTCTTTTTTCGGCATCGTGC
CGGACATCGATCTCGACGTGATGGTCCCCAACCAGACACTCAATGGGCTCATGTCCCGTGTGCTGGCACGCCTTGACGAG
GCCCTGGCCACCCACCGCCCCGATTATGTGCTGGTTCATGGCGATACCACGACCGCGCTCGCGGCCACGCTTGCTGCCTT
TCATCGGGGCATTCCCGTGGGCCATGTGGAAGCCGGCCTGCGCACCTACGACCTCACCCAGCCCTGGCCGGAGGAAATGA
ACCGTCAGGTGGTGGACCGCATGGCCCGCGACCTCTTCAGCCCCACCGAGCAGTCCGCCGCGCATCTGCGCGACGAACGG
GCACCAGGGCGGATTTTCGTTACCGGCAATACGGTCATCGACGCGCTGCTGATGACGCTCGGCCGCATCGATGCGGATGC
GGAACTGAAAGCCACCCTCGACCGGCAGTTCTCCTTCCTGGACCCCGGTCGACGCCTCGTGCTGGTGACGGGACACCGGC
GGGAGAATTTCGGCGAAGGTTTTGCCCAGATCTGCGAAGCGCTGGCCGCGCTCGCGCAGAGGCAGGACATCGAGATCGTC
TACCCTGTCCACCTCAATCCGAATGTCCGCGGGCCGGTGCACGAACGCCTTTCAGGAAAGCCGAACCTGCACCTCATCGC
GCCGCTCGACTACGTCCCGTTCGTTGCCCTGATGCGTCGGGCGAACGTCATCCTCACCGATTCCGGCGGCGTGCAGGAGG
AGGCCCCGTCCCTCGGCAAGCCGGTCCTCGTGATGCGGGACGTGACCGAGCGCCCCGAGGCCGTCGCGGCGGGCACGGTG
GAACTTGTGGGGACCGACGCCGCCCGCATCGTCGCGCATGTCACCCGCATTCTCGATCGTGCCGACAGTCCGTCGGCTTC
GGCTGCGCGCATCAACCCCTATGGCGACGGCGGCGCCAGCCGTCGCATCGTGGACGTGTTGTGCGGACGCATTCCGCTCC
CTTTCCATGACCGTGCGGCGCAGCGGCCCGCACGCATGCGGAGGTAA

Upstream 100 bases:

>100_bases
CAGTCATTCATATATCGTCGTTCCATGCTAGGCCATCGCCTGCAGGGAGCGCGTCAGGTCTCGCAACAGGGGCCGATCAA
CAGGTGATAACCGGTACCTC

Downstream 100 bases:

>100_bases
TTTAATAAATGATCGGTCATAGAGCTCTTCAGGCCTCGAAAGGCCGGTCCGTCACGCGTTCGAGGGTCGTAATGTCTGTC
CACTACAACCGTTTCAAGAG

Product: UDP-N-acetylglucosamine 2-epimerase

Products: NA

Alternate protein names: UDP-GlcNAc-2-epimerase [H]

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MKVMSIFGTRPEAIKMAPLVRAIEASADLSGLVCVTGQHRAMLDQVLSFFGIVPDIDLDVMVPNQTLNGLMSRVLARLDE
ALATHRPDYVLVHGDTTTALAATLAAFHRGIPVGHVEAGLRTYDLTQPWPEEMNRQVVDRMARDLFSPTEQSAAHLRDER
APGRIFVTGNTVIDALLMTLGRIDADAELKATLDRQFSFLDPGRRLVLVTGHRRENFGEGFAQICEALAALAQRQDIEIV
YPVHLNPNVRGPVHERLSGKPNLHLIAPLDYVPFVALMRRANVILTDSGGVQEEAPSLGKPVLVMRDVTERPEAVAAGTV
ELVGTDAARIVAHVTRILDRADSPSASAARINPYGDGGASRRIVDVLCGRIPLPFHDRAAQRPARMRR

Sequences:

>Translated_388_residues
MKVMSIFGTRPEAIKMAPLVRAIEASADLSGLVCVTGQHRAMLDQVLSFFGIVPDIDLDVMVPNQTLNGLMSRVLARLDE
ALATHRPDYVLVHGDTTTALAATLAAFHRGIPVGHVEAGLRTYDLTQPWPEEMNRQVVDRMARDLFSPTEQSAAHLRDER
APGRIFVTGNTVIDALLMTLGRIDADAELKATLDRQFSFLDPGRRLVLVTGHRRENFGEGFAQICEALAALAQRQDIEIV
YPVHLNPNVRGPVHERLSGKPNLHLIAPLDYVPFVALMRRANVILTDSGGVQEEAPSLGKPVLVMRDVTERPEAVAAGTV
ELVGTDAARIVAHVTRILDRADSPSASAARINPYGDGGASRRIVDVLCGRIPLPFHDRAAQRPARMRR
>Mature_388_residues
MKVMSIFGTRPEAIKMAPLVRAIEASADLSGLVCVTGQHRAMLDQVLSFFGIVPDIDLDVMVPNQTLNGLMSRVLARLDE
ALATHRPDYVLVHGDTTTALAATLAAFHRGIPVGHVEAGLRTYDLTQPWPEEMNRQVVDRMARDLFSPTEQSAAHLRDER
APGRIFVTGNTVIDALLMTLGRIDADAELKATLDRQFSFLDPGRRLVLVTGHRRENFGEGFAQICEALAALAQRQDIEIV
YPVHLNPNVRGPVHERLSGKPNLHLIAPLDYVPFVALMRRANVILTDSGGVQEEAPSLGKPVLVMRDVTERPEAVAAGTV
ELVGTDAARIVAHVTRILDRADSPSASAARINPYGDGGASRRIVDVLCGRIPLPFHDRAAQRPARMRR

Specific function: Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues [H]

COG id: COG0381

COG function: function code M; UDP-N-acetylglucosamine 2-epimerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-N-acetylglucosamine 2-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI48994967, Length=369, Percent_Identity=58.8075880758808, Blast_Score=405, Evalue=1e-114,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003331 [H]

Pfam domain/function: PF02350 Epimerase_2 [H]

EC number: =5.1.3.14 [H]

Molecular weight: Translated: 42412; Mature: 42412

Theoretical pI: Translated: 7.16; Mature: 7.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVMSIFGTRPEAIKMAPLVRAIEASADLSGLVCVTGQHRAMLDQVLSFFGIVPDIDLDV
CCCEEECCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHCCCCCCCEEE
MVPNQTLNGLMSRVLARLDEALATHRPDYVLVHGDTTTALAATLAAFHRGIPVGHVEAGL
EECCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHCCCCCCHHHCCC
RTYDLTQPWPEEMNRQVVDRMARDLFSPTEQSAAHLRDERAPGRIFVTGNTVIDALLMTL
EEEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEEECHHHHHHHHHHH
GRIDADAELKATLDRQFSFLDPGRRLVLVTGHRRENFGEGFAQICEALAALAQRQDIEIV
HCCCCCCHHHHHHHHCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCEEE
YPVHLNPNVRGPVHERLSGKPNLHLIAPLDYVPFVALMRRANVILTDSGGVQEEAPSLGK
EEEECCCCCCCCHHHHHCCCCCEEEEECCHHHHHHHHHHHCCEEEECCCCCCCCCCCCCC
PVLVMRDVTERPEAVAAGTVELVGTDAARIVAHVTRILDRADSPSASAARINPYGDGGAS
CEEEEECCCCCCCHHHCCCEEEECCCHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCH
RRIVDVLCGRIPLPFHDRAAQRPARMRR
HHHHHHHHCCCCCCCCHHHHCCCHHCCC
>Mature Secondary Structure
MKVMSIFGTRPEAIKMAPLVRAIEASADLSGLVCVTGQHRAMLDQVLSFFGIVPDIDLDV
CCCEEECCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHCCCCCCCEEE
MVPNQTLNGLMSRVLARLDEALATHRPDYVLVHGDTTTALAATLAAFHRGIPVGHVEAGL
EECCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHCCCCCCHHHCCC
RTYDLTQPWPEEMNRQVVDRMARDLFSPTEQSAAHLRDERAPGRIFVTGNTVIDALLMTL
EEEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEEECHHHHHHHHHHH
GRIDADAELKATLDRQFSFLDPGRRLVLVTGHRRENFGEGFAQICEALAALAQRQDIEIV
HCCCCCCHHHHHHHHCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCEEE
YPVHLNPNVRGPVHERLSGKPNLHLIAPLDYVPFVALMRRANVILTDSGGVQEEAPSLGK
EEEECCCCCCCCHHHHHCCCCCEEEEECCHHHHHHHHHHHCCEEEECCCCCCCCCCCCCC
PVLVMRDVTERPEAVAAGTVELVGTDAARIVAHVTRILDRADSPSASAARINPYGDGGAS
CEEEEECCCCCCCHHHCCCEEEECCCHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCH
RRIVDVLCGRIPLPFHDRAAQRPARMRR
HHHHHHHHCCCCCCCCHHHHCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]