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The map label for this gene is ctaD [H]

Identifier: 158424583

GI number: 158424583

Start: 3379083

End: 3380789

Strand: Reverse

Name: ctaD [H]

Synonym: AZC_2959

Alternate gene names: 158424583

Gene position: 3380789-3379083 (Counterclockwise)

Preceding gene: 158424584

Following gene: 158424582

Centisome position: 62.96

GC content: 64.62

Gene sequence:

>1707_bases
GTGGCGCATCGCCATCCAGGGGCCGCCCCGGCGGCCCGCATCAGGGATCAGGGCAGGCCGCGAACGCCGACGGCGCCCTT
CGGGATCGAGGACTGGACCATGGCCACTCAGGCAGCATCCTACGGCGCCCATGACGACCACGTGCCGACCGGCTGGCGGC
GCTGGGTGTTCTCCACGAACAACAAGGACATCGGCATCATGTACCTGATCTTCGCCATCGTGGCGGGGATCGTGGGCGGC
GCCCTGTCCATCGGCATCCGGCTGGAGCTCATGGAGCCCGGCCTCCAGTACTTCAAGAATCCGCAGACCTTCAACGTCTT
CACCACGGGCCACGGCCTCATCATGATCTTCTTCATGGTGATGCCCGCGCTGATCGGAGGTTTCGGCAACTACTTCGTGC
CGCTGATGATCGGCGCCCCCGACACCGCCTTCCCGCGCATCAACAACATCGCCTTCTGGCTGCTGGTGCCGGCCTTCGCG
CTGGCCATCATGTCGCTGTTCGTGGAAGGCGCGGCGGGCTCGGACGGCTTCGGCGGCGGCTGGACCATCTATCCGCCGCT
CTCCTCCAAGCTCGGCCATCCCGGCCCGGCCATGGATCTGCTGATCTTCTCGCTGCACGTGGCGGGCGCTTCGTCCATCC
TCGGCGCGATCAATCTCATCACCACCATCTTCAACATGCGCGCCCCCGGCATGACGCTGCACAAGATGCCGCTGTTTGCC
TGGGCGCAGCTCATCACCGCCTTCCTGCTGCTGCTGTCGCTGCCCGTGCTTGCCGGCGCCATCACCATGCTGCTGACGGA
CCGCAACTTCGGCACCACCTTCTTCGATCCGGCGGGCGGCGGCGACCCGATCCTGTTCCAGCACCTGTTCTGGTTCTTCG
GCCACCCCGAGGTCTACATCCTCATCCTGCCCGGCTTCGGCATCATCTCGCACATCATCTCCACCTTCTCGCGCAAGCCC
GTGTTCGGCTATCTCGGCATGGCCTATGCGATGGTGGCCATCGGCGTGGTGGGCTTCGTGGTGTGGGCGCACCACATGTA
CACGGTGGGCCTGTCCGCCTCGACCCAGTCCTATTTCGTCGCCGCGACCATGATCATCGCGGTGCCGACGGGCGTGAAGA
TCTTCTCCTGGATCGCCACCATGTGGGGCGGCTCGCTGCAGTTCCGCACGCCCATGCTGTGGTCGATCGGCTTCATCTTC
CTGTTCACGGTGGGCGGCGTGACCGGCGTCGTGCTCTCCAACGCCGGCATCGACCGCTCGCTGCACGACACCTATTACGT
GGTGGCCCACTTCCACTACGTGCTTTCTCTGGGCGCCGTCTTCGCCATCTTCGCCGGCTGGTACTACTGGTTCCCGAAGA
TGAGCGGTTACATGATCCCGGAATTCTGGGGCAAGCTGCACTTCTGGGTCACGTTCATCGGCGTGAACATGGTGTTCTTT
CCGCAGCACTTCCTCGGCCTTGCCGGCATGCCGCGCCGCTATGCGGACTATCCGGACGCCTTCGCCCACTGGAACTACAT
CTCCTCCATCGGCTCCTACATCTCGGGCGTCGCGGTGATCATCTTCCTCATCGGAACGGCGCTGGCCTTCGTCCGCAAGG
AGAAGGCGGGCGACAATCCGTGGGGGGCGGGTGCCACCACCCTCGAGTGGACCCTTCCGTCTCCGCCGCCGTATCACCAC
TTCGAGGTGCTGCCGCGCATCAAGTGA

Upstream 100 bases:

>100_bases
ACACGCAGGCGCCGGTGCCCACACAGGTGGCGGACGCCGCCCCGGCGCGCTGAGCTTTCCGCCCGCCGTAGCATGCGGGC
GGGCGATCTGACATTCGCGG

Downstream 100 bases:

>100_bases
GGTCCGCCGGAGCGGGGCAGGGGTCCGCCCCTGCTCCGTCCGGGTCCGCTCCGGCCATGCGCCGGACGCCGGTCACCTCC
AGAGTGCGGGCGCGAGGGGC

Product: cytochrome C oxidase subunit I

Products: NA

Alternate protein names: Cytochrome aa3 subunit 1; Cytochrome c oxidase polypeptide I [H]

Number of amino acids: Translated: 568; Mature: 567

Protein sequence:

>568_residues
MAHRHPGAAPAARIRDQGRPRTPTAPFGIEDWTMATQAASYGAHDDHVPTGWRRWVFSTNNKDIGIMYLIFAIVAGIVGG
ALSIGIRLELMEPGLQYFKNPQTFNVFTTGHGLIMIFFMVMPALIGGFGNYFVPLMIGAPDTAFPRINNIAFWLLVPAFA
LAIMSLFVEGAAGSDGFGGGWTIYPPLSSKLGHPGPAMDLLIFSLHVAGASSILGAINLITTIFNMRAPGMTLHKMPLFA
WAQLITAFLLLLSLPVLAGAITMLLTDRNFGTTFFDPAGGGDPILFQHLFWFFGHPEVYILILPGFGIISHIISTFSRKP
VFGYLGMAYAMVAIGVVGFVVWAHHMYTVGLSASTQSYFVAATMIIAVPTGVKIFSWIATMWGGSLQFRTPMLWSIGFIF
LFTVGGVTGVVLSNAGIDRSLHDTYYVVAHFHYVLSLGAVFAIFAGWYYWFPKMSGYMIPEFWGKLHFWVTFIGVNMVFF
PQHFLGLAGMPRRYADYPDAFAHWNYISSIGSYISGVAVIIFLIGTALAFVRKEKAGDNPWGAGATTLEWTLPSPPPYHH
FEVLPRIK

Sequences:

>Translated_568_residues
MAHRHPGAAPAARIRDQGRPRTPTAPFGIEDWTMATQAASYGAHDDHVPTGWRRWVFSTNNKDIGIMYLIFAIVAGIVGG
ALSIGIRLELMEPGLQYFKNPQTFNVFTTGHGLIMIFFMVMPALIGGFGNYFVPLMIGAPDTAFPRINNIAFWLLVPAFA
LAIMSLFVEGAAGSDGFGGGWTIYPPLSSKLGHPGPAMDLLIFSLHVAGASSILGAINLITTIFNMRAPGMTLHKMPLFA
WAQLITAFLLLLSLPVLAGAITMLLTDRNFGTTFFDPAGGGDPILFQHLFWFFGHPEVYILILPGFGIISHIISTFSRKP
VFGYLGMAYAMVAIGVVGFVVWAHHMYTVGLSASTQSYFVAATMIIAVPTGVKIFSWIATMWGGSLQFRTPMLWSIGFIF
LFTVGGVTGVVLSNAGIDRSLHDTYYVVAHFHYVLSLGAVFAIFAGWYYWFPKMSGYMIPEFWGKLHFWVTFIGVNMVFF
PQHFLGLAGMPRRYADYPDAFAHWNYISSIGSYISGVAVIIFLIGTALAFVRKEKAGDNPWGAGATTLEWTLPSPPPYHH
FEVLPRIK
>Mature_567_residues
AHRHPGAAPAARIRDQGRPRTPTAPFGIEDWTMATQAASYGAHDDHVPTGWRRWVFSTNNKDIGIMYLIFAIVAGIVGGA
LSIGIRLELMEPGLQYFKNPQTFNVFTTGHGLIMIFFMVMPALIGGFGNYFVPLMIGAPDTAFPRINNIAFWLLVPAFAL
AIMSLFVEGAAGSDGFGGGWTIYPPLSSKLGHPGPAMDLLIFSLHVAGASSILGAINLITTIFNMRAPGMTLHKMPLFAW
AQLITAFLLLLSLPVLAGAITMLLTDRNFGTTFFDPAGGGDPILFQHLFWFFGHPEVYILILPGFGIISHIISTFSRKPV
FGYLGMAYAMVAIGVVGFVVWAHHMYTVGLSASTQSYFVAATMIIAVPTGVKIFSWIATMWGGSLQFRTPMLWSIGFIFL
FTVGGVTGVVLSNAGIDRSLHDTYYVVAHFHYVLSLGAVFAIFAGWYYWFPKMSGYMIPEFWGKLHFWVTFIGVNMVFFP
QHFLGLAGMPRRYADYPDAFAHWNYISSIGSYISGVAVIIFLIGTALAFVRKEKAGDNPWGAGATTLEWTLPSPPPYHHF
EVLPRIK

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=513, Percent_Identity=61.7933723196881, Blast_Score=601, Evalue=1e-172,
Organism=Escherichia coli, GI1786634, Length=522, Percent_Identity=43.1034482758621, Blast_Score=399, Evalue=1e-112,
Organism=Saccharomyces cerevisiae, GI6226519, Length=531, Percent_Identity=57.4387947269303, Blast_Score=603, Evalue=1e-173,
Organism=Saccharomyces cerevisiae, GI6226524, Length=327, Percent_Identity=63.914373088685, Blast_Score=422, Evalue=1e-119,
Organism=Saccharomyces cerevisiae, GI6226523, Length=252, Percent_Identity=57.9365079365079, Blast_Score=271, Evalue=2e-73,
Organism=Saccharomyces cerevisiae, GI6226522, Length=79, Percent_Identity=50.6329113924051, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6226521, Length=66, Percent_Identity=51.5151515151515, Blast_Score=73, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014241 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 62386; Mature: 62255

Theoretical pI: Translated: 9.30; Mature: 9.30

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHRHPGAAPAARIRDQGRPRTPTAPFGIEDWTMATQAASYGAHDDHVPTGWRRWVFSTN
CCCCCCCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHEEEEECC
NKDIGIMYLIFAIVAGIVGGALSIGIRLELMEPGLQYFKNPQTFNVFTTGHGLIMIFFMV
CCCHHHHHHHHHHHHHHHHHHHHEEEEEEEEHHHHHHHCCCCEEEEEECCCHHHHHHHHH
MPALIGGFGNYFVPLMIGAPDTAFPRINNIAFWLLVPAFALAIMSLFVEGAAGSDGFGGG
HHHHHCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
WTIYPPLSSKLGHPGPAMDLLIFSLHVAGASSILGAINLITTIFNMRAPGMTLHKMPLFA
CEECCCCHHCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
WAQLITAFLLLLSLPVLAGAITMLLTDRNFGTTFFDPAGGGDPILFQHLFWFFGHPEVYI
HHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCEECCCCCCCHHHHHHHHHHHCCCCEEE
LILPGFGIISHIISTFSRKPVFGYLGMAYAMVAIGVVGFVVWAHHMYTVGLSASTQSYFV
EEECCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHH
AATMIIAVPTGVKIFSWIATMWGGSLQFRTPMLWSIGFIFLFTVGGVTGVVLSNAGIDRS
HHHEEHHCCCCHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHHHHHHEECCCCCCC
LHDTYYVVAHFHYVLSLGAVFAIFAGWYYWFPKMSGYMIPEFWGKLHFWVTFIGVNMVFF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
PQHFLGLAGMPRRYADYPDAFAHWNYISSIGSYISGVAVIIFLIGTALAFVRKEKAGDNP
HHHHHHCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
WGAGATTLEWTLPSPPPYHHFEVLPRIK
CCCCCCEEEEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AHRHPGAAPAARIRDQGRPRTPTAPFGIEDWTMATQAASYGAHDDHVPTGWRRWVFSTN
CCCCCCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHEEEEECC
NKDIGIMYLIFAIVAGIVGGALSIGIRLELMEPGLQYFKNPQTFNVFTTGHGLIMIFFMV
CCCHHHHHHHHHHHHHHHHHHHHEEEEEEEEHHHHHHHCCCCEEEEEECCCHHHHHHHHH
MPALIGGFGNYFVPLMIGAPDTAFPRINNIAFWLLVPAFALAIMSLFVEGAAGSDGFGGG
HHHHHCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
WTIYPPLSSKLGHPGPAMDLLIFSLHVAGASSILGAINLITTIFNMRAPGMTLHKMPLFA
CEECCCCHHCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
WAQLITAFLLLLSLPVLAGAITMLLTDRNFGTTFFDPAGGGDPILFQHLFWFFGHPEVYI
HHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCEECCCCCCCHHHHHHHHHHHCCCCEEE
LILPGFGIISHIISTFSRKPVFGYLGMAYAMVAIGVVGFVVWAHHMYTVGLSASTQSYFV
EEECCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHH
AATMIIAVPTGVKIFSWIATMWGGSLQFRTPMLWSIGFIFLFTVGGVTGVVLSNAGIDRS
HHHEEHHCCCCHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHHHHHHEECCCCCCC
LHDTYYVVAHFHYVLSLGAVFAIFAGWYYWFPKMSGYMIPEFWGKLHFWVTFIGVNMVFF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
PQHFLGLAGMPRRYADYPDAFAHWNYISSIGSYISGVAVIIFLIGTALAFVRKEKAGDNP
HHHHHHCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
WGAGATTLEWTLPSPPPYHHFEVLPRIK
CCCCCCEEEEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2172930; 1965217; 12597275 [H]