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The map label for this gene is ctaB [H]

Identifier: 158424582

GI number: 158424582

Start: 3377908

End: 3378852

Strand: Reverse

Name: ctaB [H]

Synonym: AZC_2958

Alternate gene names: 158424582

Gene position: 3378852-3377908 (Counterclockwise)

Preceding gene: 158424583

Following gene: 158424581

Centisome position: 62.92

GC content: 67.94

Gene sequence:

>945_bases
ATGAGCGACGTGAGCGTAGGATTGAACGAGAATGCGGGGCGCAGCCTCGCACCGCAGGCCTCGGAAGGGCTTGGAACCCC
GCGGGACTACATCTCCCTGCTGAAGCCGCGCGTGATGTCGCTGGTGATCTTCACCGCGCTCGTCGGTCTCGTGCGCGCCC
CTGATCACGTTCATCCCGTCATCGCCTTCACCGCCATTCTCTGCATCGCGGTCGGCGCCGGTGCCGCCGGTGCGCTCAAC
ATGTGGTGGGACGCGGACATCGACGCCGTCATGTCCCGCACCCAGCGCCGCCCCATTCCGGCCGGCCGCGTCACGCCACG
GGAGGCGCTCGCCTTCGGCCTGACGCTGGCCGCCTTCTCGGTGGTCGTGCTGGGCCTCCTGGTGAATGTGCTGGCCGGCG
CGCTGCTCGCCTTCACCATCTTCTTCTACGTGGTGGTCTACACCATGTGGCTGAAGCGCTCGACGCCGCAGAACATTGTC
ATCGGCGGCCTTTCGGGCGCTTTGCCGCCCATGGTCGCCTGGGCGGCTGCGTCCGGCAGCATCAGCCTCGAGAGCGTCAT
CCTCGTCGCCATCATCTTCTTCTGGACCCCGCCGCACTTCTGGGCGCTGTCCCTCTACCGGGCGGATGACTATGCCCGCG
CCGGCGTGCCCATGCTGCCGGTGACGGCGGGGCCGGACGAGACGCGCAAGCAGATCCTGCTCTACACGCTCTTCCTCGTG
CCGCTGGCCCTCTCCCCGGTGATGCTGGGCGAGGCGGGCCTTGCCTATGGCGTCGTCGCGGGCGTCACCGGCCTCGGCAT
GCTGCTGCTGGCGGTGAATGTCTATCGCCGCCGCACGGGCCCCGCCGCCGTCACCGCCGCCAAGAAGCTCTTCGGCTTCT
CCATCCTGTATCTGTTCCTGCTGTTCGCCACCCTTCTGGCGGAAGCGCTGGTGAGGGGGATGTGA

Upstream 100 bases:

>100_bases
GGCGGCATTGAAGCGGGCCGGCCTCCGGTTTTTCCCGGAGGCCCAGTTCCGGCCCCGGCGTCCGGCACGGCGCCGGGCCG
GACCCGGTGGATGAGAAGTC

Downstream 100 bases:

>100_bases
GCCCTTGGGTCAGACGGTGAAGCGAAAGCCGGCCCCGCCGCCGGAGCGCAAGACGCCTCCGGCGCCGCCGCCCCCCGAGG
ACGGCGTGGTGCTGACCCCC

Product: protoheme IX farnesyltransferase

Products: NA

Alternate protein names: Heme B farnesyltransferase; Heme O synthase [H]

Number of amino acids: Translated: 314; Mature: 313

Protein sequence:

>314_residues
MSDVSVGLNENAGRSLAPQASEGLGTPRDYISLLKPRVMSLVIFTALVGLVRAPDHVHPVIAFTAILCIAVGAGAAGALN
MWWDADIDAVMSRTQRRPIPAGRVTPREALAFGLTLAAFSVVVLGLLVNVLAGALLAFTIFFYVVVYTMWLKRSTPQNIV
IGGLSGALPPMVAWAAASGSISLESVILVAIIFFWTPPHFWALSLYRADDYARAGVPMLPVTAGPDETRKQILLYTLFLV
PLALSPVMLGEAGLAYGVVAGVTGLGMLLLAVNVYRRRTGPAAVTAAKKLFGFSILYLFLLFATLLAEALVRGM

Sequences:

>Translated_314_residues
MSDVSVGLNENAGRSLAPQASEGLGTPRDYISLLKPRVMSLVIFTALVGLVRAPDHVHPVIAFTAILCIAVGAGAAGALN
MWWDADIDAVMSRTQRRPIPAGRVTPREALAFGLTLAAFSVVVLGLLVNVLAGALLAFTIFFYVVVYTMWLKRSTPQNIV
IGGLSGALPPMVAWAAASGSISLESVILVAIIFFWTPPHFWALSLYRADDYARAGVPMLPVTAGPDETRKQILLYTLFLV
PLALSPVMLGEAGLAYGVVAGVTGLGMLLLAVNVYRRRTGPAAVTAAKKLFGFSILYLFLLFATLLAEALVRGM
>Mature_313_residues
SDVSVGLNENAGRSLAPQASEGLGTPRDYISLLKPRVMSLVIFTALVGLVRAPDHVHPVIAFTAILCIAVGAGAAGALNM
WWDADIDAVMSRTQRRPIPAGRVTPREALAFGLTLAAFSVVVLGLLVNVLAGALLAFTIFFYVVVYTMWLKRSTPQNIVI
GGLSGALPPMVAWAAASGSISLESVILVAIIFFWTPPHFWALSLYRADDYARAGVPMLPVTAGPDETRKQILLYTLFLVP
LALSPVMLGEAGLAYGVVAGVTGLGMLLLAVNVYRRRTGPAAVTAAKKLFGFSILYLFLLFATLLAEALVRGM

Specific function: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group [H]

COG id: COG0109

COG function: function code O; Polyprenyltransferase (cytochrome oxidase assembly factor)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily [H]

Homologues:

Organism=Homo sapiens, GI17921982, Length=194, Percent_Identity=36.5979381443299, Blast_Score=112, Evalue=6e-25,
Organism=Escherichia coli, GI1786631, Length=278, Percent_Identity=31.6546762589928, Blast_Score=118, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI71998235, Length=198, Percent_Identity=35.3535353535354, Blast_Score=91, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6325085, Length=261, Percent_Identity=30.6513409961686, Blast_Score=101, Evalue=1e-22,
Organism=Drosophila melanogaster, GI19921064, Length=291, Percent_Identity=31.6151202749141, Blast_Score=117, Evalue=7e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006369
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.-

Molecular weight: Translated: 33354; Mature: 33223

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDVSVGLNENAGRSLAPQASEGLGTPRDYISLLKPRVMSLVIFTALVGLVRAPDHVHPV
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
IAFTAILCIAVGAGAAGALNMWWDADIDAVMSRTQRRPIPAGRVTPREALAFGLTLAAFS
HHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
VVVLGLLVNVLAGALLAFTIFFYVVVYTMWLKRSTPQNIVIGGLSGALPPMVAWAAASGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHCCCC
ISLESVILVAIIFFWTPPHFWALSLYRADDYARAGVPMLPVTAGPDETRKQILLYTLFLV
CHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHCCCCEEEECCCCCHHHHHHHHHHHHHH
PLALSPVMLGEAGLAYGVVAGVTGLGMLLLAVNVYRRRTGPAAVTAAKKLFGFSILYLFL
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
LFATLLAEALVRGM
HHHHHHHHHHHHCC
>Mature Secondary Structure 
SDVSVGLNENAGRSLAPQASEGLGTPRDYISLLKPRVMSLVIFTALVGLVRAPDHVHPV
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
IAFTAILCIAVGAGAAGALNMWWDADIDAVMSRTQRRPIPAGRVTPREALAFGLTLAAFS
HHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
VVVLGLLVNVLAGALLAFTIFFYVVVYTMWLKRSTPQNIVIGGLSGALPPMVAWAAASGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHCCCC
ISLESVILVAIIFFWTPPHFWALSLYRADDYARAGVPMLPVTAGPDETRKQILLYTLFLV
CHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHCCCCEEEECCCCCHHHHHHHHHHHHHH
PLALSPVMLGEAGLAYGVVAGVTGLGMLLLAVNVYRRRTGPAAVTAAKKLFGFSILYLFL
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
LFATLLAEALVRGM
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA