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The map label for this gene is ctaC [H]

Identifier: 158424584

GI number: 158424584

Start: 3380837

End: 3381778

Strand: Reverse

Name: ctaC [H]

Synonym: AZC_2960

Alternate gene names: 158424584

Gene position: 3381778-3380837 (Counterclockwise)

Preceding gene: 158424589

Following gene: 158424583

Centisome position: 62.98

GC content: 65.29

Gene sequence:

>942_bases
GTGCACGGCAATCACGGGTTGTGTGCCCGGGCGTTTGGGCGCCAGGGAAGACACGTCCGGCGGCTCTGCCGCCCTCGGAG
AGGGCCTAAGATGATGTCATTGCGCCGCGCCGGTGCGCTCGCCGTTGCTGCCTCCTGCTGGATGGGCCTGTCGCTTGCGG
CCGCCCATGCAGGATTGGGGCAACCGTCCGACTGGCAGATGAACCTTCAGCAGGCGGCGACGCCGGTGATGGAGAGCATT
CGCTCCTTCAACACCTTCCTGCTGGTGATCATCTCGTCCATCGTGCTGTTCGTGCTCGTGCTGCTGGCGATCTGCATCGT
CCGCTTCAACGAGAAGGCCAATCCGGTCCCTTCCAAGACCACGCACAACACGCTGCTGGAAGTGGCCTGGACGGTCGTGC
CGGTGATGATCCTGGTGGCGATCGCCATTCCCTCCTTCCGCCTGCTGCATCTCGAGCTGCACACGCCCGAGCCGGACATG
ACGGTGAAGGTGACGGGGCACCAGTGGTACTGGTCCTACGAATATCCCGACAATGGCGGTTTCGGCTTCGATTCGCTGAT
GGTCGCGGAGAAGGACCTGAAGCCCGGCCAGCCGCGCCTGCTGGCGGTGGACAATGAGGTGGTGGTGCCGGTGAACAAGG
TGGTGCGCATCCACGTCACCAGCGCCGACGTCATCCACTCCTTCGCCGTGCCGTCCTTCGGCGTGAAGATCGACGCGATT
CCGGGCCGCCTCAACGAGTCGTGGTTCAAGGCGACCAAGGAAGGCGTGTATTATGGCCAGTGCTCGGAGCTCTGCGGCCG
CGACCACGCCTTCATGCCGCTGGCGGTGCGCGTGGTGAGCCAGCAGGATTTCGATGCCTGGCTGGCGCAGGCCAAGCAGA
AGTTCGCCGACACGCAGGCGCCGGTGCCCACACAGGTGGCGGACGCCGCCCCGGCGCGCTGA

Upstream 100 bases:

>100_bases
TGTGTCGCATGTGGGGCAGGGGTGTGCTGATTGCGGCTCGTCGCAAATTTGTGTTTGATGTAAATCAAGAAAGAAGCCAA
AGCGCCGCTGTGCGGTAAAA

Downstream 100 bases:

>100_bases
GCTTTCCGCCCGCCGTAGCATGCGGGCGGGCGATCTGACATTCGCGGGTGGCGCATCGCCATCCAGGGGCCGCCCCGGCG
GCCCGCATCAGGGATCAGGG

Product: cytochrome C oxidase subunit II

Products: NA

Alternate protein names: Cytochrome aa3 subunit 2; Cytochrome c oxidase polypeptide II [H]

Number of amino acids: Translated: 313; Mature: 313

Protein sequence:

>313_residues
MHGNHGLCARAFGRQGRHVRRLCRPRRGPKMMSLRRAGALAVAASCWMGLSLAAAHAGLGQPSDWQMNLQQAATPVMESI
RSFNTFLLVIISSIVLFVLVLLAICIVRFNEKANPVPSKTTHNTLLEVAWTVVPVMILVAIAIPSFRLLHLELHTPEPDM
TVKVTGHQWYWSYEYPDNGGFGFDSLMVAEKDLKPGQPRLLAVDNEVVVPVNKVVRIHVTSADVIHSFAVPSFGVKIDAI
PGRLNESWFKATKEGVYYGQCSELCGRDHAFMPLAVRVVSQQDFDAWLAQAKQKFADTQAPVPTQVADAAPAR

Sequences:

>Translated_313_residues
MHGNHGLCARAFGRQGRHVRRLCRPRRGPKMMSLRRAGALAVAASCWMGLSLAAAHAGLGQPSDWQMNLQQAATPVMESI
RSFNTFLLVIISSIVLFVLVLLAICIVRFNEKANPVPSKTTHNTLLEVAWTVVPVMILVAIAIPSFRLLHLELHTPEPDM
TVKVTGHQWYWSYEYPDNGGFGFDSLMVAEKDLKPGQPRLLAVDNEVVVPVNKVVRIHVTSADVIHSFAVPSFGVKIDAI
PGRLNESWFKATKEGVYYGQCSELCGRDHAFMPLAVRVVSQQDFDAWLAQAKQKFADTQAPVPTQVADAAPAR
>Mature_313_residues
MHGNHGLCARAFGRQGRHVRRLCRPRRGPKMMSLRRAGALAVAASCWMGLSLAAAHAGLGQPSDWQMNLQQAATPVMESI
RSFNTFLLVIISSIVLFVLVLLAICIVRFNEKANPVPSKTTHNTLLEVAWTVVPVMILVAIAIPSFRLLHLELHTPEPDM
TVKVTGHQWYWSYEYPDNGGFGFDSLMVAEKDLKPGQPRLLAVDNEVVVPVNKVVRIHVTSADVIHSFAVPSFGVKIDAI
PGRLNESWFKATKEGVYYGQCSELCGRDHAFMPLAVRVVSQQDFDAWLAQAKQKFADTQAPVPTQVADAAPAR

Specific function: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) [H]

COG id: COG1622

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 2

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 2 family [H]

Homologues:

Organism=Homo sapiens, GI251831110, Length=220, Percent_Identity=43.1818181818182, Blast_Score=204, Evalue=8e-53,
Organism=Escherichia coli, GI1786635, Length=220, Percent_Identity=27.7272727272727, Blast_Score=77, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6226540, Length=235, Percent_Identity=41.2765957446808, Blast_Score=179, Evalue=4e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001505
- InterPro:   IPR008972
- InterPro:   IPR014222
- InterPro:   IPR015964
- InterPro:   IPR002429
- InterPro:   IPR011759 [H]

Pfam domain/function: PF00116 COX2; PF02790 COX2_TM [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 34514; Mature: 34514

Theoretical pI: Translated: 9.28; Mature: 9.28

Prosite motif: PS00078 COX2 ; PS50999 COX2_TM ; PS50857 COX2_CUA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHGNHGLCARAFGRQGRHVRRLCRPRRGPKMMSLRRAGALAVAASCWMGLSLAAAHAGLG
CCCCCCCHHHHHCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
QPSDWQMNLQQAATPVMESIRSFNTFLLVIISSIVLFVLVLLAICIVRFNEKANPVPSKT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
THNTLLEVAWTVVPVMILVAIAIPSFRLLHLELHTPEPDMTVKVTGHQWYWSYEYPDNGG
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCEEEEEECCEEEEEEECCCCCC
FGFDSLMVAEKDLKPGQPRLLAVDNEVVVPVNKVVRIHVTSADVIHSFAVPSFGVKIDAI
CCHHHHHEECCCCCCCCCEEEEECCCEEEECCEEEEEEECHHHHHHHHCCCCCCEEEECC
PGRLNESWFKATKEGVYYGQCSELCGRDHAFMPLAVRVVSQQDFDAWLAQAKQKFADTQA
CCCCCHHHHHHHHCCEEEECHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCC
PVPTQVADAAPAR
CCCCHHCCCCCCC
>Mature Secondary Structure
MHGNHGLCARAFGRQGRHVRRLCRPRRGPKMMSLRRAGALAVAASCWMGLSLAAAHAGLG
CCCCCCCHHHHHCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
QPSDWQMNLQQAATPVMESIRSFNTFLLVIISSIVLFVLVLLAICIVRFNEKANPVPSKT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
THNTLLEVAWTVVPVMILVAIAIPSFRLLHLELHTPEPDMTVKVTGHQWYWSYEYPDNGG
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCEEEEEECCEEEEEEECCCCCC
FGFDSLMVAEKDLKPGQPRLLAVDNEVVVPVNKVVRIHVTSADVIHSFAVPSFGVKIDAI
CCHHHHHEECCCCCCCCCEEEEECCCEEEECCEEEEEEECHHHHHHHHCCCCCCEEEECC
PGRLNESWFKATKEGVYYGQCSELCGRDHAFMPLAVRVVSQQDFDAWLAQAKQKFADTQA
CCCCCHHHHHHHHCCEEEECHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCC
PVPTQVADAAPAR
CCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA