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The map label for this gene is ttuB [H]

Identifier: 158424502

GI number: 158424502

Start: 3278669

End: 3279997

Strand: Direct

Name: ttuB [H]

Synonym: AZC_2878

Alternate gene names: 158424502

Gene position: 3278669-3279997 (Clockwise)

Preceding gene: 158424501

Following gene: 158424503

Centisome position: 61.06

GC content: 68.62

Gene sequence:

>1329_bases
ATGGATGCGGGAGCGGGATTGACGGCGGAAGAGAAGCTGACCTTCGCCAAGGTGGCGCGGCGGCTCATCCCGTTCATGAT
GCTCCTGTATCTCGTGAGCTTCCTCGACCGGGTGAACGTCGGTTTTGCCGCCCTCACCATGAATGCGGACCTCGGCTTCT
CGCCGCAGGTCTATGGCTGGGGCGCCGGCATCTTCTTCATCGGCTATTTCCTGTTCGAGGTGCCCTCCAATCTCGTGCTG
GAAAAGGTGGGCGCGCGGCTCTGGATCTGCCGCATCATGGTCACCTGGGGCCTCATCTCCGCCGCCACCGCCTTCGTGAC
CGGCCCAACCTCCTTCTTCCTCCTGCGCTTCCTCCTCGGCGCGGCGGAGGCCGGCTTCCTGCCGGGCATGATCCTTTATC
TCGGCACCTGGTTTCCGCTCGCCATGCGGGCGCGCTATGTCGCCCTCTTCATGGCGGCCGTGCCTATCGCCAGCGCGGTG
GGCTCGCCGCTATCGGCCCTGATCATGCAGAGCCACGGCTTTGGCGGCCTCGCCGGCTGGCAATGGCTGTTCATCATCGA
AGGACTGCCCGCCGTCCTGCTCGGCCTCGTGGTGCTGGTGCTGCTGCCGGACGGCCCGGCGGACGCCCGCTGGCTGACTG
CGCGCGAACAGCAGGTGATCGCAGACCGGCTGGCGAAGGACAACGCAGCGGGCGATGCCACCACCCGCCACGCCTTGTGG
CCCGCGCTCCGGGATGGGCGGGTGCTGCTGCTGGGGCTCGTCTATTTCGGACTGGTGGTCGGGCTCTACGGCATCGGCCT
CTGGCTGCCGCAGATCATCCGTGACATGGGCTACAGCGTCGAGCAGGTGGGGTTGCTGCTCGTCCTGCCCTATGCCCTGA
GCGCCGCCGCCATGCTGGCCTGGGGCCGCCACAGCGACCGTTCGGGGGAGCGCATCCTGCACGTGGCGGGCGCGGCCTTC
CTCGGCGCGGCTGGGCTTTTGGCGAGCGTGCATGTCCCGACGCCCCTGTTGGCCATCGGCGCGGTCACCTGTGCCTCCGT
CGGCATCTATGCGGCGCTCGGCCCCTTCTGGTCGGTGCCCCCGCTCTTCCTGCGCGGAACCGCGGCCGCCGCCGGCATCG
CCCTCATCAATGCCGTAGGCAATCTTGGTGGCTTTGCCGGTCCCTATGCGGTGGGCTTCATCAAGCAGCATACCGACCGC
TTCACCGCCGCTTTCGAGCTGCTGGCTGGCGTGGTCCTCCTCGCCGGCCTCCTCGCCCTCGTCCTGCGGGCGTTCCTGCG
CCAGCGGGGCAACCTGCCGGCCCCACGACAGGTCGCCCGCCGCCCCTGA

Upstream 100 bases:

>100_bases
TTCTTGAATCGCTCTCTAGAGGCCCAGCACCGTTGCCCGTTGACGATCCGGCATCCCGCAGCCATGAACGGCAGACGGGG
CCGGGAGCGCAGAGCCGAGC

Downstream 100 bases:

>100_bases
CACATCGGGGGCGTCCGGCAGGCGGACAGGTCCGTTTTTCCGCTACGCCCGGAAGCAGCCGTCGCCTTAGACGAAGACAA
GAAGAAGCATGTGGGAGGAT

Product: major facilitator superfamily permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 442; Mature: 442

Protein sequence:

>442_residues
MDAGAGLTAEEKLTFAKVARRLIPFMMLLYLVSFLDRVNVGFAALTMNADLGFSPQVYGWGAGIFFIGYFLFEVPSNLVL
EKVGARLWICRIMVTWGLISAATAFVTGPTSFFLLRFLLGAAEAGFLPGMILYLGTWFPLAMRARYVALFMAAVPIASAV
GSPLSALIMQSHGFGGLAGWQWLFIIEGLPAVLLGLVVLVLLPDGPADARWLTAREQQVIADRLAKDNAAGDATTRHALW
PALRDGRVLLLGLVYFGLVVGLYGIGLWLPQIIRDMGYSVEQVGLLLVLPYALSAAAMLAWGRHSDRSGERILHVAGAAF
LGAAGLLASVHVPTPLLAIGAVTCASVGIYAALGPFWSVPPLFLRGTAAAAGIALINAVGNLGGFAGPYAVGFIKQHTDR
FTAAFELLAGVVLLAGLLALVLRAFLRQRGNLPAPRQVARRP

Sequences:

>Translated_442_residues
MDAGAGLTAEEKLTFAKVARRLIPFMMLLYLVSFLDRVNVGFAALTMNADLGFSPQVYGWGAGIFFIGYFLFEVPSNLVL
EKVGARLWICRIMVTWGLISAATAFVTGPTSFFLLRFLLGAAEAGFLPGMILYLGTWFPLAMRARYVALFMAAVPIASAV
GSPLSALIMQSHGFGGLAGWQWLFIIEGLPAVLLGLVVLVLLPDGPADARWLTAREQQVIADRLAKDNAAGDATTRHALW
PALRDGRVLLLGLVYFGLVVGLYGIGLWLPQIIRDMGYSVEQVGLLLVLPYALSAAAMLAWGRHSDRSGERILHVAGAAF
LGAAGLLASVHVPTPLLAIGAVTCASVGIYAALGPFWSVPPLFLRGTAAAAGIALINAVGNLGGFAGPYAVGFIKQHTDR
FTAAFELLAGVVLLAGLLALVLRAFLRQRGNLPAPRQVARRP
>Mature_442_residues
MDAGAGLTAEEKLTFAKVARRLIPFMMLLYLVSFLDRVNVGFAALTMNADLGFSPQVYGWGAGIFFIGYFLFEVPSNLVL
EKVGARLWICRIMVTWGLISAATAFVTGPTSFFLLRFLLGAAEAGFLPGMILYLGTWFPLAMRARYVALFMAAVPIASAV
GSPLSALIMQSHGFGGLAGWQWLFIIEGLPAVLLGLVVLVLLPDGPADARWLTAREQQVIADRLAKDNAAGDATTRHALW
PALRDGRVLLLGLVYFGLVVGLYGIGLWLPQIIRDMGYSVEQVGLLLVLPYALSAAAMLAWGRHSDRSGERILHVAGAAF
LGAAGLLASVHVPTPLLAIGAVTCASVGIYAALGPFWSVPPLFLRGTAAAAGIALINAVGNLGGFAGPYAVGFIKQHTDR
FTAAFELLAGVVLLAGLLALVLRAFLRQRGNLPAPRQVARRP

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Escherichia coli, GI87082071, Length=370, Percent_Identity=40.5405405405405, Blast_Score=251, Evalue=6e-68,
Organism=Escherichia coli, GI2367379, Length=441, Percent_Identity=25.8503401360544, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI1789515, Length=435, Percent_Identity=23.2183908045977, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1789152, Length=459, Percent_Identity=24.6187363834423, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI87082320, Length=434, Percent_Identity=21.4285714285714, Blast_Score=64, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6321698, Length=323, Percent_Identity=27.8637770897833, Blast_Score=106, Evalue=7e-24,
Organism=Saccharomyces cerevisiae, GI6322025, Length=298, Percent_Identity=26.510067114094, Blast_Score=104, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6322612, Length=296, Percent_Identity=25, Blast_Score=95, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6324410, Length=166, Percent_Identity=25.3012048192771, Blast_Score=84, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6319876, Length=207, Percent_Identity=28.9855072463768, Blast_Score=77, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6319250, Length=262, Percent_Identity=27.8625954198473, Blast_Score=76, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6323032, Length=220, Percent_Identity=23.1818181818182, Blast_Score=63, Evalue=8e-11,
Organism=Drosophila melanogaster, GI19922400, Length=416, Percent_Identity=21.6346153846154, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24654215, Length=416, Percent_Identity=21.6346153846154, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46997; Mature: 46997

Theoretical pI: Translated: 10.06; Mature: 10.06

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAGAGLTAEEKLTFAKVARRLIPFMMLLYLVSFLDRVNVGFAALTMNADLGFSPQVYGW
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCC
GAGIFFIGYFLFEVPSNLVLEKVGARLWICRIMVTWGLISAATAFVTGPTSFFLLRFLLG
CHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
AAEAGFLPGMILYLGTWFPLAMRARYVALFMAAVPIASAVGSPLSALIMQSHGFGGLAGW
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHH
QWLFIIEGLPAVLLGLVVLVLLPDGPADARWLTAREQQVIADRLAKDNAAGDATTRHALW
HHHHHHHCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
PALRDGRVLLLGLVYFGLVVGLYGIGLWLPQIIRDMGYSVEQVGLLLVLPYALSAAAMLA
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
WGRHSDRSGERILHVAGAAFLGAAGLLASVHVPTPLLAIGAVTCASVGIYAALGPFWSVP
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
PLFLRGTAAAAGIALINAVGNLGGFAGPYAVGFIKQHTDRFTAAFELLAGVVLLAGLLAL
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLRAFLRQRGNLPAPRQVARRP
HHHHHHHHCCCCCCCHHHCCCC
>Mature Secondary Structure
MDAGAGLTAEEKLTFAKVARRLIPFMMLLYLVSFLDRVNVGFAALTMNADLGFSPQVYGW
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCC
GAGIFFIGYFLFEVPSNLVLEKVGARLWICRIMVTWGLISAATAFVTGPTSFFLLRFLLG
CHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
AAEAGFLPGMILYLGTWFPLAMRARYVALFMAAVPIASAVGSPLSALIMQSHGFGGLAGW
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHH
QWLFIIEGLPAVLLGLVVLVLLPDGPADARWLTAREQQVIADRLAKDNAAGDATTRHALW
HHHHHHHCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
PALRDGRVLLLGLVYFGLVVGLYGIGLWLPQIIRDMGYSVEQVGLLLVLPYALSAAAMLA
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
WGRHSDRSGERILHVAGAAFLGAAGLLASVHVPTPLLAIGAVTCASVGIYAALGPFWSVP
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
PLFLRGTAAAAGIALINAVGNLGGFAGPYAVGFIKQHTDRFTAAFELLAGVVLLAGLLAL
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLRAFLRQRGNLPAPRQVARRP
HHHHHHHHCCCCCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]