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The map label for this gene is yngJ [H]

Identifier: 158424501

GI number: 158424501

Start: 3277255

End: 3278409

Strand: Direct

Name: yngJ [H]

Synonym: AZC_2877

Alternate gene names: 158424501

Gene position: 3277255-3278409 (Clockwise)

Preceding gene: 158424500

Following gene: 158424502

Centisome position: 61.03

GC content: 71.17

Gene sequence:

>1155_bases
ATGAATTTCGACCTGTCGGACGAGCAGGCCCTGCTGCGGGACACGGTGCAGCGCTGGGCGGCAACCATCTATCCCGGCCT
CGAACAGCTGGAAGCCGCGCGCCGCGCGCCGCTGGGCTTCCTGGAGAACCGCTGGGCCGAGCTGGCCGAGCTCGGCCTGC
TCGGCCTGCCCTTCGCGGAGGAAGACGGCGGCTTCGGCGGCGGCCCTGTGGAGCTGCTGGTGGTGGCCGAAGCCCTCGGC
CGCGCGCTGGCGCCGGAGCCCTATCTCGCCAGCATCGTGCTCGGCGGCGGCGCCCTGCGCCTCGCCGGCTCGCAGGCGCA
GAAGGACGCGCTCCTGCCAGGCGTCATCGACGGCTCCGTCCGCCTTGCCTTCGCCCATGGCGAGGCGCAGGCGCGCTACG
ACCTGAACGATGTGGCCACCACCGCCCGTGCGGTGGAAGGCGGCTACCGGCTGGACGGACGCAAGAGCGTGGTGCTGAAT
GCGGATGCCGCGCAGACCCTCGTGGTGAGCGCCCGCACAGCGGGCGGGCGACGGGATGAGGCGGGCATCACGCTCTTCCT
CGTGCCAGCCGATGCCCCCGGTGTGACCCTCGCGCCCTACCCGACGCACGATGGCGGCCGCGCGGCCGACGTGGTCCTCG
CCGACGTGTTCGTGCCCACGGAGGCCGTGCTCGGCCCGCAGGACGCCGCCCTGCCGATCATCGAGCGCATCATCGACGGC
GGCATCGTCGCGCTCTGCGCCGAGGCCGTGGGCCTCATGGAAGCGCTGCACGAGCTGACCATCGAGTATCTGAAGACCCG
CAAGCAGTTCGGCGTCTCCATCGGCTCCTTCCAGGCGCTCCAGCACAAGGCCGTGGACATGCTGGTGGCGCTGGAGCAGG
CCCGCTCCATGGCGCTCTATGCGGCCATGATGGTGGAGGCCGAGGATGCGGAGGAGCGCCGCGTCGCCCTCTCCGCCGCC
AAGGCGCAGATCAACCGCTCCGCCCGTTTCGTGGGACAGACGGCGGTGCAGCTCCATGGCGGCATCGGCATGACCATGGA
ATATCTCGGCGCGCACCACTTCCGCAGGCTGGCGGCCATCGAGCTGACCTTCGGCGACACGCCCTTTCACACCCGCCGCG
TGGCGAGCGAGAAGGGCCTCGTTGGAGCCGACTGA

Upstream 100 bases:

>100_bases
ATGCGCAAGGTGTCCATCTACGGCGGGTCCAACGAGATCCAGCACAATGTGATCGCCAAGGCGATCCTCGGCCTGTGACG
GACGGCGCGGAGAGACTGTC

Downstream 100 bases:

>100_bases
CCTTCCGCGGGTGAAGTGATCCGCCAGAGGCGTCCGCTTCACCCGCGCGAACTCCAGGTGCCGCAGATACTGGCAGGCCC
TGGCATCGGTCATCGTGGCC

Product: acyl-CoA dehydrogenase

Products: 6-carboxyhex-2-enoyl-CoA; NADH; H+

Alternate protein names: NA

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MNFDLSDEQALLRDTVQRWAATIYPGLEQLEAARRAPLGFLENRWAELAELGLLGLPFAEEDGGFGGGPVELLVVAEALG
RALAPEPYLASIVLGGGALRLAGSQAQKDALLPGVIDGSVRLAFAHGEAQARYDLNDVATTARAVEGGYRLDGRKSVVLN
ADAAQTLVVSARTAGGRRDEAGITLFLVPADAPGVTLAPYPTHDGGRAADVVLADVFVPTEAVLGPQDAALPIIERIIDG
GIVALCAEAVGLMEALHELTIEYLKTRKQFGVSIGSFQALQHKAVDMLVALEQARSMALYAAMMVEAEDAEERRVALSAA
KAQINRSARFVGQTAVQLHGGIGMTMEYLGAHHFRRLAAIELTFGDTPFHTRRVASEKGLVGAD

Sequences:

>Translated_384_residues
MNFDLSDEQALLRDTVQRWAATIYPGLEQLEAARRAPLGFLENRWAELAELGLLGLPFAEEDGGFGGGPVELLVVAEALG
RALAPEPYLASIVLGGGALRLAGSQAQKDALLPGVIDGSVRLAFAHGEAQARYDLNDVATTARAVEGGYRLDGRKSVVLN
ADAAQTLVVSARTAGGRRDEAGITLFLVPADAPGVTLAPYPTHDGGRAADVVLADVFVPTEAVLGPQDAALPIIERIIDG
GIVALCAEAVGLMEALHELTIEYLKTRKQFGVSIGSFQALQHKAVDMLVALEQARSMALYAAMMVEAEDAEERRVALSAA
KAQINRSARFVGQTAVQLHGGIGMTMEYLGAHHFRRLAAIELTFGDTPFHTRRVASEKGLVGAD
>Mature_384_residues
MNFDLSDEQALLRDTVQRWAATIYPGLEQLEAARRAPLGFLENRWAELAELGLLGLPFAEEDGGFGGGPVELLVVAEALG
RALAPEPYLASIVLGGGALRLAGSQAQKDALLPGVIDGSVRLAFAHGEAQARYDLNDVATTARAVEGGYRLDGRKSVVLN
ADAAQTLVVSARTAGGRRDEAGITLFLVPADAPGVTLAPYPTHDGGRAADVVLADVFVPTEAVLGPQDAALPIIERIIDG
GIVALCAEAVGLMEALHELTIEYLKTRKQFGVSIGSFQALQHKAVDMLVALEQARSMALYAAMMVEAEDAEERRVALSAA
KAQINRSARFVGQTAVQLHGGIGMTMEYLGAHHFRRLAAIELTFGDTPFHTRRVASEKGLVGAD

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=322, Percent_Identity=28.8819875776398, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI226958412, Length=354, Percent_Identity=28.5310734463277, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI226958414, Length=313, Percent_Identity=29.073482428115, Blast_Score=102, Evalue=8e-22,
Organism=Homo sapiens, GI4501859, Length=363, Percent_Identity=26.7217630853994, Blast_Score=99, Evalue=9e-21,
Organism=Homo sapiens, GI187960098, Length=356, Percent_Identity=26.9662921348315, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI4557231, Length=356, Percent_Identity=26.9662921348315, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI4501857, Length=352, Percent_Identity=25.2840909090909, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI76496475, Length=318, Percent_Identity=27.9874213836478, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI4557235, Length=318, Percent_Identity=27.9874213836478, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI7656849, Length=359, Percent_Identity=24.5125348189415, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI21361497, Length=314, Percent_Identity=27.3885350318471, Blast_Score=83, Evalue=4e-16,
Organism=Escherichia coli, GI87081958, Length=363, Percent_Identity=25.3443526170799, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1786223, Length=362, Percent_Identity=25.414364640884, Blast_Score=75, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17538396, Length=355, Percent_Identity=28.7323943661972, Blast_Score=108, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17506239, Length=364, Percent_Identity=27.1978021978022, Blast_Score=100, Evalue=9e-22,
Organism=Caenorhabditis elegans, GI17534899, Length=355, Percent_Identity=25.0704225352113, Blast_Score=95, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17569725, Length=361, Percent_Identity=26.8698060941828, Blast_Score=95, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17508101, Length=360, Percent_Identity=26.1111111111111, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI71985184, Length=318, Percent_Identity=27.0440251572327, Blast_Score=85, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI71990804, Length=263, Percent_Identity=27.3764258555133, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17570075, Length=358, Percent_Identity=25.1396648044693, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17551932, Length=328, Percent_Identity=25.3048780487805, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17533517, Length=340, Percent_Identity=23.2352941176471, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71985192, Length=293, Percent_Identity=26.6211604095563, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI32563615, Length=244, Percent_Identity=27.0491803278689, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71982178, Length=282, Percent_Identity=26.9503546099291, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24646207, Length=331, Percent_Identity=29.0030211480363, Blast_Score=112, Evalue=5e-25,
Organism=Drosophila melanogaster, GI21356377, Length=336, Percent_Identity=26.1904761904762, Blast_Score=108, Evalue=9e-24,
Organism=Drosophila melanogaster, GI21355753, Length=315, Percent_Identity=30.7936507936508, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24666513, Length=362, Percent_Identity=26.7955801104972, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24660351, Length=354, Percent_Identity=26.5536723163842, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI281363737, Length=318, Percent_Identity=27.6729559748428, Blast_Score=88, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.1.62

Molecular weight: Translated: 40639; Mature: 40639

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFDLSDEQALLRDTVQRWAATIYPGLEQLEAARRAPLGFLENRWAELAELGLLGLPFAE
CCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCC
EDGGFGGGPVELLVVAEALGRALAPEPYLASIVLGGGALRLAGSQAQKDALLPGVIDGSV
CCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCEEEECCCCHHHCCCCCCEECCCE
RLAFAHGEAQARYDLNDVATTARAVEGGYRLDGRKSVVLNADAAQTLVVSARTAGGRRDE
EEEEEECCCCCCCCHHHHHHHHHHHCCCEEECCCCEEEEECCCCEEEEEEEECCCCCCCC
AGITLFLVPADAPGVTLAPYPTHDGGRAADVVLADVFVPTEAVLGPQDAALPIIERIIDG
CCEEEEEEECCCCCCEECCCCCCCCCCCHHEEEEEHHCCCHHHCCCCCHHHHHHHHHHCC
GIVALCAEAVGLMEALHELTIEYLKTRKQFGVSIGSFQALQHKAVDMLVALEQARSMALY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAMMVEAEDAEERRVALSAAKAQINRSARFVGQTAVQLHGGIGMTMEYLGAHHFRRLAAI
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHEEEE
ELTFGDTPFHTRRVASEKGLVGAD
EEEECCCCCHHHHHHHCCCCCCCC
>Mature Secondary Structure
MNFDLSDEQALLRDTVQRWAATIYPGLEQLEAARRAPLGFLENRWAELAELGLLGLPFAE
CCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCC
EDGGFGGGPVELLVVAEALGRALAPEPYLASIVLGGGALRLAGSQAQKDALLPGVIDGSV
CCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCEEEECCCCHHHCCCCCCEECCCE
RLAFAHGEAQARYDLNDVATTARAVEGGYRLDGRKSVVLNADAAQTLVVSARTAGGRRDE
EEEEEECCCCCCCCHHHHHHHHHHHCCCEEECCCCEEEEECCCCEEEEEEEECCCCCCCC
AGITLFLVPADAPGVTLAPYPTHDGGRAADVVLADVFVPTEAVLGPQDAALPIIERIIDG
CCEEEEEEECCCCCCEECCCCCCCCCCCHHEEEEEHHCCCHHHCCCCCHHHHHHHHHHCC
GIVALCAEAVGLMEALHELTIEYLKTRKQFGVSIGSFQALQHKAVDMLVALEQARSMALY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAMMVEAEDAEERRVALSAAKAQINRSARFVGQTAVQLHGGIGMTMEYLGAHHFRRLAAI
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHEEEE
ELTFGDTPFHTRRVASEKGLVGAD
EEEECCCCCHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: pimeloyl-CoA; NAD+

Specific reaction: pimeloyl-CoA + NAD+ = 6-carboxyhex-2-enoyl-CoA + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]