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The map label for this gene is mmgC [H]

Identifier: 158424500

GI number: 158424500

Start: 3276036

End: 3277232

Strand: Direct

Name: mmgC [H]

Synonym: AZC_2876

Alternate gene names: 158424500

Gene position: 3276036-3277232 (Clockwise)

Preceding gene: 158424499

Following gene: 158424501

Centisome position: 61.01

GC content: 66.08

Gene sequence:

>1197_bases
ATGGACCTGCGCTTCACCCCCGAAGAGATCGCCTTCCGCGAGGAGGTGCGCACCTTCTTCCGCACCGAGATTCCGGCGGA
AATCCGCGCCAAGGTTTCGGAAGGCCGCAAGCTGGCGCGGGAGGATTACGTCACCTCCCAGCGCATCCTCAACGACAAGG
GCTGGGCCGTTCCCCACTGGCCGGTGGAGCACGGCGGCCAGTCGTGGAGCGCCGTGCAGCGCTACATCTTCATGGAAGAG
CTGATGCAGGCGGCCGTGCCGCTGCCGCTCCAGTTCAACTGCTTCATGGTGGGCCCGGTCATCGCCACCTTCGGCAACGA
GGCGCAGAAGCAGCGCTTCCTGCCGCGCATCAAGAGCCTGGAGGACTGGTGGTGCCAGGGCTTCTCCGAGCCCGGCGCCG
GCTCGGACCTCGCCTCGCTCAAGACCCGCGCGGTGCGCGAGGGCGACCATTACATCGTGGACGGCCAGAAGACCTGGACC
ACGCTCGGCCAGTATGCCGACTGGATGTTCTGCCTCGCCCGCACCAATCCGGACGCCAAGAAGCAGGCGGGCATCTCCTT
CCTGCTCATCGACATGAAGACCCCCGGCGTGACTGTGCGCCCCATCATCACCATCGACGGGCGGCACGAGGTCAACGAAG
TCTTCCTCGACAACGTGAAGGTGCCGGTCGAGAACCTCGTGGGCGAGGAGAACAAGGGCTGGGACTATGCCAAGTTCCTG
CTCGCCAACGAGCGCACCGGCATCGCCCGCATCGGCATGTCGAAGGAGCGGATCGCGCGCATCAAGCGGCTCGCCCGCTC
CACGCCGGCGGGCGCCGGCACCATGTGGGACGATCTCGATTTCCGCAGCCGCCTCGCGAGCGTGGAAATCGAACTGAAGG
CGCTGGAAATCACCCAAATGCGCGTGGTGGCCGCGCAGGCGACCCGCGACCCGACGAAGCCCGACCCGGCCTCCTCCATC
CTCAAGATCAAGGGCTCGGAGCTTCAGCAGGCCACCACCGAGCTGCTGCTGGAACTCGCCGGTCCCAACGGCCTGCCCGC
GCAGCGCGACGAGGCCGGGCACAACGACATGGAGAGTCTGTTCGCCTGGGCGGACACGGCGGCACCCACCTATTTCAACA
TGCGCAAGGTGTCCATCTACGGCGGGTCCAACGAGATCCAGCACAATGTGATCGCCAAGGCGATCCTCGGCCTGTGA

Upstream 100 bases:

>100_bases
AGGCCGGCGCCGGGGCGTGCGCTACGCGGTCGTCACCATGTGCATCGCCGGCGGCATGGGCGCAGCCGGCCTCATCGAAA
TCAACCCGGACGCCTAATCC

Downstream 100 bases:

>100_bases
CGGACGGCGCGGAGAGACTGTCATGAATTTCGACCTGTCGGACGAGCAGGCCCTGCTGCGGGACACGGTGCAGCGCTGGG
CGGCAACCATCTATCCCGGC

Product: acyl-CoA dehydrogenase

Products: 6-carboxyhex-2-enoyl-CoA; NADH; H+

Alternate protein names: NA

Number of amino acids: Translated: 398; Mature: 398

Protein sequence:

>398_residues
MDLRFTPEEIAFREEVRTFFRTEIPAEIRAKVSEGRKLAREDYVTSQRILNDKGWAVPHWPVEHGGQSWSAVQRYIFMEE
LMQAAVPLPLQFNCFMVGPVIATFGNEAQKQRFLPRIKSLEDWWCQGFSEPGAGSDLASLKTRAVREGDHYIVDGQKTWT
TLGQYADWMFCLARTNPDAKKQAGISFLLIDMKTPGVTVRPIITIDGRHEVNEVFLDNVKVPVENLVGEENKGWDYAKFL
LANERTGIARIGMSKERIARIKRLARSTPAGAGTMWDDLDFRSRLASVEIELKALEITQMRVVAAQATRDPTKPDPASSI
LKIKGSELQQATTELLLELAGPNGLPAQRDEAGHNDMESLFAWADTAAPTYFNMRKVSIYGGSNEIQHNVIAKAILGL

Sequences:

>Translated_398_residues
MDLRFTPEEIAFREEVRTFFRTEIPAEIRAKVSEGRKLAREDYVTSQRILNDKGWAVPHWPVEHGGQSWSAVQRYIFMEE
LMQAAVPLPLQFNCFMVGPVIATFGNEAQKQRFLPRIKSLEDWWCQGFSEPGAGSDLASLKTRAVREGDHYIVDGQKTWT
TLGQYADWMFCLARTNPDAKKQAGISFLLIDMKTPGVTVRPIITIDGRHEVNEVFLDNVKVPVENLVGEENKGWDYAKFL
LANERTGIARIGMSKERIARIKRLARSTPAGAGTMWDDLDFRSRLASVEIELKALEITQMRVVAAQATRDPTKPDPASSI
LKIKGSELQQATTELLLELAGPNGLPAQRDEAGHNDMESLFAWADTAAPTYFNMRKVSIYGGSNEIQHNVIAKAILGL
>Mature_398_residues
MDLRFTPEEIAFREEVRTFFRTEIPAEIRAKVSEGRKLAREDYVTSQRILNDKGWAVPHWPVEHGGQSWSAVQRYIFMEE
LMQAAVPLPLQFNCFMVGPVIATFGNEAQKQRFLPRIKSLEDWWCQGFSEPGAGSDLASLKTRAVREGDHYIVDGQKTWT
TLGQYADWMFCLARTNPDAKKQAGISFLLIDMKTPGVTVRPIITIDGRHEVNEVFLDNVKVPVENLVGEENKGWDYAKFL
LANERTGIARIGMSKERIARIKRLARSTPAGAGTMWDDLDFRSRLASVEIELKALEITQMRVVAAQATRDPTKPDPASSI
LKIKGSELQQATTELLLELAGPNGLPAQRDEAGHNDMESLFAWADTAAPTYFNMRKVSIYGGSNEIQHNVIAKAILGL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501859, Length=412, Percent_Identity=28.1553398058252, Blast_Score=115, Evalue=7e-26,
Organism=Homo sapiens, GI4501857, Length=401, Percent_Identity=26.1845386533666, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI187960098, Length=247, Percent_Identity=31.1740890688259, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI4557231, Length=247, Percent_Identity=31.1740890688259, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI226958412, Length=178, Percent_Identity=32.5842696629214, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI226958414, Length=178, Percent_Identity=32.5842696629214, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI4557233, Length=348, Percent_Identity=26.1494252873563, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI7656849, Length=203, Percent_Identity=28.5714285714286, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI76496475, Length=256, Percent_Identity=29.296875, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI4557235, Length=256, Percent_Identity=29.296875, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI21361497, Length=353, Percent_Identity=27.1954674220963, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI48976061, Length=240, Percent_Identity=25.8333333333333, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI211971008, Length=240, Percent_Identity=25.8333333333333, Blast_Score=73, Evalue=5e-13,
Organism=Escherichia coli, GI87081958, Length=314, Percent_Identity=26.1146496815287, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1786223, Length=363, Percent_Identity=22.3140495867769, Blast_Score=69, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17538396, Length=256, Percent_Identity=30.46875, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17569725, Length=359, Percent_Identity=24.7910863509749, Blast_Score=108, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17570075, Length=416, Percent_Identity=26.2019230769231, Blast_Score=108, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17534899, Length=208, Percent_Identity=30.7692307692308, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17506239, Length=257, Percent_Identity=29.9610894941634, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17508101, Length=200, Percent_Identity=32, Blast_Score=95, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI71985184, Length=152, Percent_Identity=35.5263157894737, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71985192, Length=152, Percent_Identity=35.5263157894737, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI32563615, Length=205, Percent_Identity=32.6829268292683, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17505929, Length=354, Percent_Identity=25.1412429378531, Blast_Score=88, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17551932, Length=212, Percent_Identity=27.3584905660377, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71990804, Length=200, Percent_Identity=28, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71982178, Length=199, Percent_Identity=28.643216080402, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17533517, Length=216, Percent_Identity=25, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24666513, Length=340, Percent_Identity=26.4705882352941, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI21356377, Length=358, Percent_Identity=26.8156424581006, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24660351, Length=194, Percent_Identity=33.5051546391753, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI21355753, Length=201, Percent_Identity=30.8457711442786, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI281363737, Length=157, Percent_Identity=30.5732484076433, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24646207, Length=353, Percent_Identity=26.3456090651558, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI19920834, Length=416, Percent_Identity=24.7596153846154, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.1.62

Molecular weight: Translated: 44666; Mature: 44666

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLRFTPEEIAFREEVRTFFRTEIPAEIRAKVSEGRKLAREDYVTSQRILNDKGWAVPHW
CCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
PVEHGGQSWSAVQRYIFMEELMQAAVPLPLQFNCFMVGPVIATFGNEAQKQRFLPRIKSL
CHHCCCCCHHHHHHHHHHHHHHHHHCCCCEEECEEEECHHHHHCCCHHHHHHHHHHHHCH
EDWWCQGFSEPGAGSDLASLKTRAVREGDHYIVDGQKTWTTLGQYADWMFCLARTNPDAK
HHHHHCCCCCCCCCCHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHEEEECCCCCHH
KQAGISFLLIDMKTPGVTVRPIITIDGRHEVNEVFLDNVKVPVENLVGEENKGWDYAKFL
HHCCCEEEEEEECCCCEEEEEEEEECCCHHHHHHHHCCCCCCHHHHCCCCCCCCCHHHHE
LANERTGIARIGMSKERIARIKRLARSTPAGAGTMWDDLDFRSRLASVEIELKALEITQM
ECCCCCCCEECCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHEEEEEEEEEHHHH
RVVAAQATRDPTKPDPASSILKIKGSELQQATTELLLELAGPNGLPAQRDEAGHNDMESL
HHHHHHHCCCCCCCCCCHHEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHH
FAWADTAAPTYFNMRKVSIYGGSNEIQHNVIAKAILGL
HHHHHCCCCCEEEEEEEEEECCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MDLRFTPEEIAFREEVRTFFRTEIPAEIRAKVSEGRKLAREDYVTSQRILNDKGWAVPHW
CCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
PVEHGGQSWSAVQRYIFMEELMQAAVPLPLQFNCFMVGPVIATFGNEAQKQRFLPRIKSL
CHHCCCCCHHHHHHHHHHHHHHHHHCCCCEEECEEEECHHHHHCCCHHHHHHHHHHHHCH
EDWWCQGFSEPGAGSDLASLKTRAVREGDHYIVDGQKTWTTLGQYADWMFCLARTNPDAK
HHHHHCCCCCCCCCCHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHEEEECCCCCHH
KQAGISFLLIDMKTPGVTVRPIITIDGRHEVNEVFLDNVKVPVENLVGEENKGWDYAKFL
HHCCCEEEEEEECCCCEEEEEEEEECCCHHHHHHHHCCCCCCHHHHCCCCCCCCCHHHHE
LANERTGIARIGMSKERIARIKRLARSTPAGAGTMWDDLDFRSRLASVEIELKALEITQM
ECCCCCCCEECCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHEEEEEEEEEHHHH
RVVAAQATRDPTKPDPASSILKIKGSELQQATTELLLELAGPNGLPAQRDEAGHNDMESL
HHHHHHHCCCCCCCCCCHHEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHH
FAWADTAAPTYFNMRKVSIYGGSNEIQHNVIAKAILGL
HHHHHCCCCCEEEEEEEEEECCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: pimeloyl-CoA; NAD+

Specific reaction: pimeloyl-CoA + NAD+ = 6-carboxyhex-2-enoyl-CoA + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]