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The map label for this gene is mcp4 [H]

Identifier: 158424363

GI number: 158424363

Start: 3109050

End: 3110873

Strand: Direct

Name: mcp4 [H]

Synonym: AZC_2739

Alternate gene names: 158424363

Gene position: 3109050-3110873 (Clockwise)

Preceding gene: 158424361

Following gene: 158424365

Centisome position: 57.9

GC content: 67.71

Gene sequence:

>1824_bases
TTGGCGCGGGGGAAAGACGCAAGCCCCGCGAAAGACTGGACGCGAACCGTGACGCGTCACCTCCGCCCATCGGCCCGTTG
CGTTCCGCCGCATATTTCGGCGCGCGCTCGTCTGCGAGATACCCCCATGTCCTATCGCAATTTTCCGATGATCTGGAAGG
TCGTCAGCCTTTTGCTCGTGCTCGGCCTCACCAGCGCGGCCGGCGCCTACTACGCCACGCACAACATCTCCGCGCTGAAC
GACATGTATCGCACCCAGGCGGAGGGGCCGCAGGCGGCAGCCATCAACATCGCCCGCGCCGGCCGTCTCGCCGCCAGCAC
CAGCGTCGCCATCTACCGGCAGGTCTCCGCCTTTTCCGACGACGACGTGAAGGCCGCCCGTGCGGCACAGGCCGAGGCAC
TGAAGGGCTTCGACGACCGCATGGGTCTCGCCGCCAAGGCCATGCCCGAAGCCGCCGACAGGATCGGCGCCGCCACCCGC
GTGCTGCACACCGCCTATGAGCAGGCCTGCGCCGAGACGCTGAAGCTTTCGAGCGTGGTTGGCGACATGACAATGAGCAC
CCGCGCCTCGCGGCTGATGCAGCGGGATTGCGAGCCGGCCCTGAACAAGACGATCACGTCGCTGGTCGAGATCAACGACA
TCATGCGGGACCGTATCGCCACGATGAATGCGGAAGGCGAGCGCACCACCAGCAACACCATTCTGCTCACCTTCGCCGGG
GTGATCGGCTCGACTGTGGTCATCATTCTCATCGCCGCCCTTCTGGTGCGCAGCGGCATCGTGGCGCCCATCAACGCCAT
GGTTGCCGCCATGACTCAGATCGGCGCCGGCAAGCTCGACGTGGCCATCACCGGCGACACCCGAAAGGACGAGATCGGCG
CCATGGCCAAGGCCCTCGACGTGCTGCGCGGACAGCTCCAGCAGGGCGAGGAGTTGCGCGCCGCACAGGCTGCCACCGAA
GCCGCCGAGCGTGAACGCCTCGCCCGCCGGGAGACCGTCGCGGTGGGCTTCGTCGCCCGCATGCAGGAACTGGCGGGCCG
CTTCGCCCAGTCCTCCGGCGAGGTGGCGAATTCCGCCCGCAACCTCTCCTCCACCGCCGAGGAGACGTCCCGTCAGGCCC
AGGCCGTGGCAAGCGCCGCCGAGCAGGCCGCGGCGAACGTGGAAACGGTGGCCTCGTCCTCGGACAGCCTCGCCATTTCG
GTGCGCGAGATCACCGGGCAGGTGGCCCACTCCGCGGAGGTGGCCGATGTGGCCTTCCGCGAAGCGGAAGCATCCAACGC
CCGCATCACGGAGCTTGCCGGGGCCGCGACCGCCATCGGCGACGTGATCAATCTCATCAAGGGCATCGCCGACCAGACGA
ACCTTCTCGCGCTTAACGCCACCATCGAGGCGGCGCGCGCGGGCGAGGCCGGCAAGGGCTTTGCGGTGGTGGCGACCGAG
GTGAAGGAACTCGCCACGCAGACGGCCCGCGCCACCAACGATATCGCCCAGAAGATCGGCGAGATCCAGACCGCGACCCG
GGGCACGGTATCGTCCATGGGCGAGATCGTGCGCGTGGTTTCCGACATCAAGTCCATCTCCGCCGCCATCGCCAGCGCGG
TGGAGGAACAGGGCGCGGCCACCGGCGAGATCGCGCAGAACTGTCAGCAGGCAGCCGTCGGCACCAATCAGGTGACCGAG
AATATCGAAGGCGTAGGTCGCGCAGCCGTCGAGACCGGTTCGGCTGCCTCGCAACTGCTCGATCTCTCGCAGGGCCTCTC
CAGCCAGGCCGCCGACCTGCGGGAGGTGGTGGAAACCTTCGTCCGCGATCTCAACGCCGCATAA

Upstream 100 bases:

>100_bases
CAGAGCGTGGCAGGAACCTGCCACGCCGGCTTCGGAAAGGCCACCAACCGGAGGGTGGCGAGCACCTGCAAATGCGCATG
GCAGCAGGGCGTCCGGCACA

Downstream 100 bases:

>100_bases
TGCCGCCTACCCCGCGCCCTTCGCGGGCGCGGGGCAGTTCAGCTAGAACCGCTCCCGATAGGCCTGCGGGGAAACTGAGA
GCAGCCGCAGGAAGCTGCGC

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 607; Mature: 606

Protein sequence:

>607_residues
MARGKDASPAKDWTRTVTRHLRPSARCVPPHISARARLRDTPMSYRNFPMIWKVVSLLLVLGLTSAAGAYYATHNISALN
DMYRTQAEGPQAAAINIARAGRLAASTSVAIYRQVSAFSDDDVKAARAAQAEALKGFDDRMGLAAKAMPEAADRIGAATR
VLHTAYEQACAETLKLSSVVGDMTMSTRASRLMQRDCEPALNKTITSLVEINDIMRDRIATMNAEGERTTSNTILLTFAG
VIGSTVVIILIAALLVRSGIVAPINAMVAAMTQIGAGKLDVAITGDTRKDEIGAMAKALDVLRGQLQQGEELRAAQAATE
AAERERLARRETVAVGFVARMQELAGRFAQSSGEVANSARNLSSTAEETSRQAQAVASAAEQAAANVETVASSSDSLAIS
VREITGQVAHSAEVADVAFREAEASNARITELAGAATAIGDVINLIKGIADQTNLLALNATIEAARAGEAGKGFAVVATE
VKELATQTARATNDIAQKIGEIQTATRGTVSSMGEIVRVVSDIKSISAAIASAVEEQGAATGEIAQNCQQAAVGTNQVTE
NIEGVGRAAVETGSAASQLLDLSQGLSSQAADLREVVETFVRDLNAA

Sequences:

>Translated_607_residues
MARGKDASPAKDWTRTVTRHLRPSARCVPPHISARARLRDTPMSYRNFPMIWKVVSLLLVLGLTSAAGAYYATHNISALN
DMYRTQAEGPQAAAINIARAGRLAASTSVAIYRQVSAFSDDDVKAARAAQAEALKGFDDRMGLAAKAMPEAADRIGAATR
VLHTAYEQACAETLKLSSVVGDMTMSTRASRLMQRDCEPALNKTITSLVEINDIMRDRIATMNAEGERTTSNTILLTFAG
VIGSTVVIILIAALLVRSGIVAPINAMVAAMTQIGAGKLDVAITGDTRKDEIGAMAKALDVLRGQLQQGEELRAAQAATE
AAERERLARRETVAVGFVARMQELAGRFAQSSGEVANSARNLSSTAEETSRQAQAVASAAEQAAANVETVASSSDSLAIS
VREITGQVAHSAEVADVAFREAEASNARITELAGAATAIGDVINLIKGIADQTNLLALNATIEAARAGEAGKGFAVVATE
VKELATQTARATNDIAQKIGEIQTATRGTVSSMGEIVRVVSDIKSISAAIASAVEEQGAATGEIAQNCQQAAVGTNQVTE
NIEGVGRAAVETGSAASQLLDLSQGLSSQAADLREVVETFVRDLNAA
>Mature_606_residues
ARGKDASPAKDWTRTVTRHLRPSARCVPPHISARARLRDTPMSYRNFPMIWKVVSLLLVLGLTSAAGAYYATHNISALND
MYRTQAEGPQAAAINIARAGRLAASTSVAIYRQVSAFSDDDVKAARAAQAEALKGFDDRMGLAAKAMPEAADRIGAATRV
LHTAYEQACAETLKLSSVVGDMTMSTRASRLMQRDCEPALNKTITSLVEINDIMRDRIATMNAEGERTTSNTILLTFAGV
IGSTVVIILIAALLVRSGIVAPINAMVAAMTQIGAGKLDVAITGDTRKDEIGAMAKALDVLRGQLQQGEELRAAQAATEA
AERERLARRETVAVGFVARMQELAGRFAQSSGEVANSARNLSSTAEETSRQAQAVASAAEQAAANVETVASSSDSLAISV
REITGQVAHSAEVADVAFREAEASNARITELAGAATAIGDVINLIKGIADQTNLLALNATIEAARAGEAGKGFAVVATEV
KELATQTARATNDIAQKIGEIQTATRGTVSSMGEIVRVVSDIKSISAAIASAVEEQGAATGEIAQNCQQAAVGTNQVTEN
IEGVGRAAVETGSAASQLLDLSQGLSSQAADLREVVETFVRDLNAA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=409, Percent_Identity=27.1393643031785, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1788194, Length=223, Percent_Identity=36.7713004484305, Blast_Score=99, Evalue=7e-22,
Organism=Escherichia coli, GI1788195, Length=301, Percent_Identity=29.5681063122924, Blast_Score=90, Evalue=5e-19,
Organism=Escherichia coli, GI1787690, Length=283, Percent_Identity=29.6819787985866, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1789453, Length=349, Percent_Identity=25.5014326647564, Blast_Score=81, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013163
- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF08269 Cache_2; PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 63446; Mature: 63315

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2 ; PS50192 T_SNARE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARGKDASPAKDWTRTVTRHLRPSARCVPPHISARARLRDTPMSYRNFPMIWKVVSLLLV
CCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHH
LGLTSAAGAYYATHNISALNDMYRTQAEGPQAAAINIARAGRLAASTSVAIYRQVSAFSD
HHHHHHCCCHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCC
DDVKAARAAQAEALKGFDDRMGLAAKAMPEAADRIGAATRVLHTAYEQACAETLKLSSVV
CHHHHHHHHHHHHHHCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GDMTMSTRASRLMQRDCEPALNKTITSLVEINDIMRDRIATMNAEGERTTSNTILLTFAG
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEHHH
VIGSTVVIILIAALLVRSGIVAPINAMVAAMTQIGAGKLDVAITGDTRKDEIGAMAKALD
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHH
VLRGQLQQGEELRAAQAATEAAERERLARRETVAVGFVARMQELAGRFAQSSGEVANSAR
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
NLSSTAEETSRQAQAVASAAEQAAANVETVASSSDSLAISVREITGQVAHSAEVADVAFR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHH
EAEASNARITELAGAATAIGDVINLIKGIADQTNLLALNATIEAARAGEAGKGFAVVATE
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHCCCCCCCHHHHHHH
VKELATQTARATNDIAQKIGEIQTATRGTVSSMGEIVRVVSDIKSISAAIASAVEEQGAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TGEIAQNCQQAAVGTNQVTENIEGVGRAAVETGSAASQLLDLSQGLSSQAADLREVVETF
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHH
VRDLNAA
HHHHCCC
>Mature Secondary Structure 
ARGKDASPAKDWTRTVTRHLRPSARCVPPHISARARLRDTPMSYRNFPMIWKVVSLLLV
CCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHH
LGLTSAAGAYYATHNISALNDMYRTQAEGPQAAAINIARAGRLAASTSVAIYRQVSAFSD
HHHHHHCCCHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCC
DDVKAARAAQAEALKGFDDRMGLAAKAMPEAADRIGAATRVLHTAYEQACAETLKLSSVV
CHHHHHHHHHHHHHHCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GDMTMSTRASRLMQRDCEPALNKTITSLVEINDIMRDRIATMNAEGERTTSNTILLTFAG
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEHHH
VIGSTVVIILIAALLVRSGIVAPINAMVAAMTQIGAGKLDVAITGDTRKDEIGAMAKALD
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHH
VLRGQLQQGEELRAAQAATEAAERERLARRETVAVGFVARMQELAGRFAQSSGEVANSAR
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
NLSSTAEETSRQAQAVASAAEQAAANVETVASSSDSLAISVREITGQVAHSAEVADVAFR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHH
EAEASNARITELAGAATAIGDVINLIKGIADQTNLLALNATIEAARAGEAGKGFAVVATE
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHCCCCCCCHHHHHHH
VKELATQTARATNDIAQKIGEIQTATRGTVSSMGEIVRVVSDIKSISAAIASAVEEQGAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TGEIAQNCQQAAVGTNQVTENIEGVGRAAVETGSAASQLLDLSQGLSSQAADLREVVETF
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHH
VRDLNAA
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]