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The map label for this gene is mcp4 [H]

Identifier: 158424197

GI number: 158424197

Start: 2898358

End: 2900454

Strand: Direct

Name: mcp4 [H]

Synonym: AZC_2573

Alternate gene names: 158424197

Gene position: 2898358-2900454 (Clockwise)

Preceding gene: 158424196

Following gene: 158424199

Centisome position: 53.98

GC content: 64.81

Gene sequence:

>2097_bases
TTGGAGAATTTTATGCGCATCCGGGGGATATTCCTCATTTGCATCGCAACGCTGGGTGCCGTGGCACTGGCGGGAAGCGT
CATGTTCGCCGTGCGCGAATGGCAGCGATGGCAATCGGCCATCAGCGCCCAAGCCTTGATGCAGGTGCTCGCAAATCTTT
CCTATTCCACCGAGCGTTTCGGACTTGAGCGCGGTGACTTCAACCAGATGCTGCTCGGCGAAAGCGCGGCATCGGAAGCG
CAGATCGCGACCACCAAGAAGAATATGGGCCGCACCGACGAAACGTTGGCTGCGGCGAAGACGCTCGCCGCATCCCTGCG
ACCGGCGGACCGCGCGATCGCCGAAGGGGCCATCACCAAGGCCATCGCGGACCTGCGGAAACTGCGGGATGATGCGTGGG
AAGAAGCGAGAAAGCCCCGCGACAGCCGGAATCCCGCCGTCACGAAGAACTTCCTCCCCTCCGCCGCAGAACTGCTGCGC
TCCGTGACCTCCCTTATGGAGGCCCTGGAACTGCGGATCGGCGACGAAGATCCGGCCATGGAAAGCTTCGTCTCTGTGGC
CCGTCTCTCGTCGGCCATGCGGGATGCGGGTGGCCGCCGTTCCGCGGTGGTCCTGCTGTATCTCGGCTCCGGGAAAAAGT
TCACGCCGGCGCAGCTTGAACAGTTCCTCATGCTCGACGGTGAGGCCGAAGCCTATTGGGCCATGGTCAAGCATGCGGCC
AAGCCGTTGGAAAATGTCCCCGGCATCAAGGAAGCGCTCGCCACGGCGCAGGACCAGTTCATCGGCGTCGGTGGCCGCAT
CACCCGCCAGATTTATGCCAGCGGGATTTCCGATACGCCCCCGCCGATGACCCTCCCGGAGTTTCGCGCGCAGATCGCGC
CTCCGCTGATCAAGGCTCTGGCGCCCCGCGATGCTGCCTTTGCAGCCGCCCAGATTCAGAGCGAACAGAATATCGGCAAC
AGCCGCACCGGTTTCATTCTCGCCTGCCTCTTCATGTTGGCCATCGTCGGTGTCGTCGCGGGCTTTGCCGTCTTCATCAC
CCATCGTGTGGTGAGGCCCATCCGCACCCTGGCCAGCGGCATCGAGAGCATCTCAAAGGGCGAGTTTGACGTGGAAATCC
CGGGCCTCGACCGCAAGGACGAGGTAGGGGAGATCGGCCGTGCCGTGGAAATCCTGCGGGGCAACAGCCAGGAGATGGTG
CGCCTGCAGGACGAGCAGGTGTCGCTTCGCGCCCAGGCCGAGGAAGAGCGGCGGCGGGCATTCGATCTCGTGGCCGACGA
ACTCGGCAGCGTGGTCGGCGAGATCGCAGGCGTGGTGTCCACCGCCTCGGAGGGCCTTCAGGCGTCCGCCCAGAGCATGC
TGACCATGGCGGAACAGACGTCCAGCCGATCCGGCGTCGCCAGCCGGGCGTCCGAAGAAGCCAACAAAATGGTGGGCGCC
GTCGCCACGGCCGCCGAGGAACTGTCCGCCTCCGTCTCGGAGATCGGCTCGCAGGTGAAGGAATCCGCCCGTGTCGCCAG
CATTGCGGTGACCGAAGCCAACGCTGCGGCCTCCAAGGTCAACACCATGTCGGAAGCGGCCCGCCGCATCGGCGACATCC
TGAGTCTGATCAGCAACATCGCTGGCCAGACCAACCTGCTGGCGCTCAACGCGACCATTGAGGCGGCCCGTGCGGGCGAG
GCGGGTCGCGGCTTTGCCGTGGTGGCCTCCGAGGTGAAGAATCTCGCGGAACAAACCTCCAAGGCCACGGCGGAAATCGA
AGCTCAGATCTCTACCGTTCAGGGCGCCACGGACGAAGCGGTATCGGCCATCACCGGCATTGCGTCCACCATCGGGCGCA
TGAACGAAATCTCCAACACCATCGCGTCGGCGGTGTCGCAGCAGACGACGGCAACGAACGAGATCGCCCATTCCATCTCG
CGCGCCTCACAGGGGGTGCGCGATGCCTCCGAGAACATGGCGGAGGTTAACCAGACGGCGGCGGACACGGGAACGACCGC
CACTCAGGTGCTCGGCGCCTCCACCGATCTGTCCCGCACGTCGGGCGAACTGCGCCGGGCGACGGAGAACTTCGTCGCCC
GCATCCGCAGCGCCTGA

Upstream 100 bases:

>100_bases
AGAAGTAGATTATAGAGACATTTTTACACCGATTAATTGCATGTTCAGACAACTCCAGCTTCAGGCAAGGTGACTGATAG
ACAGTCTCACAAGTAATAAG

Downstream 100 bases:

>100_bases
GCCCGCTCCAGCCCCCGGCCCTGCCGGGGGCTTTGCGTGCCACCTGAAGGTCCAGGTCAGCCCTCGCGGAAATCGTCGCG
GTGGTAACCTTGCATATAAA

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 698; Mature: 698

Protein sequence:

>698_residues
MENFMRIRGIFLICIATLGAVALAGSVMFAVREWQRWQSAISAQALMQVLANLSYSTERFGLERGDFNQMLLGESAASEA
QIATTKKNMGRTDETLAAAKTLAASLRPADRAIAEGAITKAIADLRKLRDDAWEEARKPRDSRNPAVTKNFLPSAAELLR
SVTSLMEALELRIGDEDPAMESFVSVARLSSAMRDAGGRRSAVVLLYLGSGKKFTPAQLEQFLMLDGEAEAYWAMVKHAA
KPLENVPGIKEALATAQDQFIGVGGRITRQIYASGISDTPPPMTLPEFRAQIAPPLIKALAPRDAAFAAAQIQSEQNIGN
SRTGFILACLFMLAIVGVVAGFAVFITHRVVRPIRTLASGIESISKGEFDVEIPGLDRKDEVGEIGRAVEILRGNSQEMV
RLQDEQVSLRAQAEEERRRAFDLVADELGSVVGEIAGVVSTASEGLQASAQSMLTMAEQTSSRSGVASRASEEANKMVGA
VATAAEELSASVSEIGSQVKESARVASIAVTEANAAASKVNTMSEAARRIGDILSLISNIAGQTNLLALNATIEAARAGE
AGRGFAVVASEVKNLAEQTSKATAEIEAQISTVQGATDEAVSAITGIASTIGRMNEISNTIASAVSQQTTATNEIAHSIS
RASQGVRDASENMAEVNQTAADTGTTATQVLGASTDLSRTSGELRRATENFVARIRSA

Sequences:

>Translated_698_residues
MENFMRIRGIFLICIATLGAVALAGSVMFAVREWQRWQSAISAQALMQVLANLSYSTERFGLERGDFNQMLLGESAASEA
QIATTKKNMGRTDETLAAAKTLAASLRPADRAIAEGAITKAIADLRKLRDDAWEEARKPRDSRNPAVTKNFLPSAAELLR
SVTSLMEALELRIGDEDPAMESFVSVARLSSAMRDAGGRRSAVVLLYLGSGKKFTPAQLEQFLMLDGEAEAYWAMVKHAA
KPLENVPGIKEALATAQDQFIGVGGRITRQIYASGISDTPPPMTLPEFRAQIAPPLIKALAPRDAAFAAAQIQSEQNIGN
SRTGFILACLFMLAIVGVVAGFAVFITHRVVRPIRTLASGIESISKGEFDVEIPGLDRKDEVGEIGRAVEILRGNSQEMV
RLQDEQVSLRAQAEEERRRAFDLVADELGSVVGEIAGVVSTASEGLQASAQSMLTMAEQTSSRSGVASRASEEANKMVGA
VATAAEELSASVSEIGSQVKESARVASIAVTEANAAASKVNTMSEAARRIGDILSLISNIAGQTNLLALNATIEAARAGE
AGRGFAVVASEVKNLAEQTSKATAEIEAQISTVQGATDEAVSAITGIASTIGRMNEISNTIASAVSQQTTATNEIAHSIS
RASQGVRDASENMAEVNQTAADTGTTATQVLGASTDLSRTSGELRRATENFVARIRSA
>Mature_698_residues
MENFMRIRGIFLICIATLGAVALAGSVMFAVREWQRWQSAISAQALMQVLANLSYSTERFGLERGDFNQMLLGESAASEA
QIATTKKNMGRTDETLAAAKTLAASLRPADRAIAEGAITKAIADLRKLRDDAWEEARKPRDSRNPAVTKNFLPSAAELLR
SVTSLMEALELRIGDEDPAMESFVSVARLSSAMRDAGGRRSAVVLLYLGSGKKFTPAQLEQFLMLDGEAEAYWAMVKHAA
KPLENVPGIKEALATAQDQFIGVGGRITRQIYASGISDTPPPMTLPEFRAQIAPPLIKALAPRDAAFAAAQIQSEQNIGN
SRTGFILACLFMLAIVGVVAGFAVFITHRVVRPIRTLASGIESISKGEFDVEIPGLDRKDEVGEIGRAVEILRGNSQEMV
RLQDEQVSLRAQAEEERRRAFDLVADELGSVVGEIAGVVSTASEGLQASAQSMLTMAEQTSSRSGVASRASEEANKMVGA
VATAAEELSASVSEIGSQVKESARVASIAVTEANAAASKVNTMSEAARRIGDILSLISNIAGQTNLLALNATIEAARAGE
AGRGFAVVASEVKNLAEQTSKATAEIEAQISTVQGATDEAVSAITGIASTIGRMNEISNTIASAVSQQTTATNEIAHSIS
RASQGVRDASENMAEVNQTAADTGTTATQVLGASTDLSRTSGELRRATENFVARIRSA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788194, Length=222, Percent_Identity=35.5855855855856, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1787690, Length=375, Percent_Identity=28, Blast_Score=100, Evalue=6e-22,
Organism=Escherichia coli, GI2367378, Length=347, Percent_Identity=29.3948126801153, Blast_Score=97, Evalue=5e-21,
Organism=Escherichia coli, GI1788195, Length=180, Percent_Identity=38.3333333333333, Blast_Score=97, Evalue=5e-21,
Organism=Escherichia coli, GI1789453, Length=334, Percent_Identity=27.8443113772455, Blast_Score=89, Evalue=7e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013163
- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF08269 Cache_2; PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 73836; Mature: 73836

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2 ; PS50192 T_SNARE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENFMRIRGIFLICIATLGAVALAGSVMFAVREWQRWQSAISAQALMQVLANLSYSTERF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
GLERGDFNQMLLGESAASEAQIATTKKNMGRTDETLAAAKTLAASLRPADRAIAEGAITK
CCCCCCCHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHH
AIADLRKLRDDAWEEARKPRDSRNPAVTKNFLPSAAELLRSVTSLMEALELRIGDEDPAM
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCHHH
ESFVSVARLSSAMRDAGGRRSAVVLLYLGSGKKFTPAQLEQFLMLDGEAEAYWAMVKHAA
HHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHH
KPLENVPGIKEALATAQDQFIGVGGRITRQIYASGISDTPPPMTLPEFRAQIAPPLIKAL
HHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHH
APRDAAFAAAQIQSEQNIGNSRTGFILACLFMLAIVGVVAGFAVFITHRVVRPIRTLASG
CCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IESISKGEFDVEIPGLDRKDEVGEIGRAVEILRGNSQEMVRLQDEQVSLRAQAEEERRRA
HHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
FDLVADELGSVVGEIAGVVSTASEGLQASAQSMLTMAEQTSSRSGVASRASEEANKMVGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
VATAAEELSASVSEIGSQVKESARVASIAVTEANAAASKVNTMSEAARRIGDILSLISNI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGQTNLLALNATIEAARAGEAGRGFAVVASEVKNLAEQTSKATAEIEAQISTVQGATDEA
CCCCEEEEEECHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
VSAITGIASTIGRMNEISNTIASAVSQQTTATNEIAHSISRASQGVRDASENMAEVNQTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ADTGTTATQVLGASTDLSRTSGELRRATENFVARIRSA
CCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MENFMRIRGIFLICIATLGAVALAGSVMFAVREWQRWQSAISAQALMQVLANLSYSTERF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
GLERGDFNQMLLGESAASEAQIATTKKNMGRTDETLAAAKTLAASLRPADRAIAEGAITK
CCCCCCCHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHH
AIADLRKLRDDAWEEARKPRDSRNPAVTKNFLPSAAELLRSVTSLMEALELRIGDEDPAM
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCHHH
ESFVSVARLSSAMRDAGGRRSAVVLLYLGSGKKFTPAQLEQFLMLDGEAEAYWAMVKHAA
HHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHH
KPLENVPGIKEALATAQDQFIGVGGRITRQIYASGISDTPPPMTLPEFRAQIAPPLIKAL
HHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHH
APRDAAFAAAQIQSEQNIGNSRTGFILACLFMLAIVGVVAGFAVFITHRVVRPIRTLASG
CCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IESISKGEFDVEIPGLDRKDEVGEIGRAVEILRGNSQEMVRLQDEQVSLRAQAEEERRRA
HHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
FDLVADELGSVVGEIAGVVSTASEGLQASAQSMLTMAEQTSSRSGVASRASEEANKMVGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
VATAAEELSASVSEIGSQVKESARVASIAVTEANAAASKVNTMSEAARRIGDILSLISNI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGQTNLLALNATIEAARAGEAGRGFAVVASEVKNLAEQTSKATAEIEAQISTVQGATDEA
CCCCEEEEEECHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
VSAITGIASTIGRMNEISNTIASAVSQQTTATNEIAHSISRASQGVRDASENMAEVNQTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ADTGTTATQVLGASTDLSRTSGELRRATENFVARIRSA
CCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]