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The map label for this gene is ppiD [H]

Identifier: 158423833

GI number: 158423833

Start: 2523537

End: 2525453

Strand: Reverse

Name: ppiD [H]

Synonym: AZC_2209

Alternate gene names: 158423833

Gene position: 2525453-2523537 (Counterclockwise)

Preceding gene: 158423836

Following gene: 158423832

Centisome position: 47.03

GC content: 67.24

Gene sequence:

>1917_bases
GTGCTCCTCGAACCAGACCGAACGATGGTACTCCAGAATCTCCGCAAGGGCGCATCCGGCCTGATCGCCAAGGTCTTCCT
CCTCGTGCTGACGGTCAGCTTCGTCCTCTGGGGTATCTCCGGCGTCTTCACCAATTACAGCACCGGCACGGTGGCGGAGA
TCGGCGGCACGCAGATCTCGACCGACGCCTATCGCCAGCAGTATCTGGACCAGATCCAGCGCATCGGCCGGCAGGCCGGC
CGGGCGATCACGCCCGATCAGGCGCGCGCCTTCGGTTTCGACCGTCAGGTGCTGAATCAGATGATCACCGAGGCGACGCT
GGACGAGGCAGCCCGCAAGCTCGGCCTCGGCATGTCCGACGCCCTGATCGCGGACAGCATCCGCGACAATCCGGCCCTGC
GGCCGCCGGGGGCGACGGCCTTCGATCCCGCCTATTTCCAGCAGCTTCTCCAGGCCAACGGGCTCACCGAGCAGCGCTTC
CTCGCCTCCGAGCGCAAGCGCGTGCTGCGCCAGCAGCTCATCGAATCGCTGGGCGGCGCCCGCGCGCCCGAGGTGCTGAA
GACGGCGGTGCACAGCTTCGAGAATGAGGAGCGCGCGGTCTCCTATCTGGACGTGACCTCCAGCTCCGTGCCCGCCCCGG
CCGCGCCCACGGACGAACAGCTCAAGGCCTATTATGACGGCCACAAGGTGGTGTTCCGCGCGCCGGAATATCGCAAGCTG
ACGCTGCTCGTGCTCACGCCCGCGACGCTGGCGCCGTGGATCCAGATTTCGGATGCCGACGCCAAGGCCGCCTACGACCG
CAACGCCGCCCGCTTCGGCACGCCCGAACAGCGCGACGTGCAGCAGATCGTGTTCCCCAGTGAGGCGGATGCGAAGGCGG
CGCTGGACAAGATCAAGGGTGGCACGAGCTTCGCTGACATCGCCAAGGCGCGCGGCCTCTCCGACAAGGACACCAACCTC
GGCCTCGTGGCGAAGTCCGCCATCATCGATCCCAAGGTTGCAGACGCCGCCTTCGCCCTTCCAGCGGACGGCACGTCCGA
TCCGGTACAGGGCCGCTTTGGCTATGCGCTGGTGCATGTGACGACGATCGTTCCCGCGACCGTCAAGCCCTTCGCGGAAG
TGGAAGCAGGCCTGCGGCGCGATCTCGCTCTGGAGCGCGCGCGGCGGGAGCTTCTGGACAAGCACGATGCCATCGAAGAC
GAGCGCTCCTCCGGCGCCTCGCTCAGCGAGACGGCGCAGAAGCTCGGTCTCACGCCCGAGGTGGTCGATGCGGTGGACCG
CTCGGGCCGCGAGCCCTCCGGCGCCGAGGTCACCGACATTCCCGACCGCGTCAATGTGCTGAGTGCCGCCTTCTCCAGCC
GGCCGGGCGTCGACAACGATCCGATCCAGCTGGCGCAGAACGGCGGCTATGTGTGGTTCGACGTGAACGAGGTCACCCCC
TCCCGCGAGCGTCCCTTCGACGAGGTGCGCGAGCAGGTGGCGTCCCGCTGGAGCGAGGACGAGGTGGTCAGGGCGGTTGA
AGCCAAGGCCAAGGGTCTGCTGACGGAACTCGAGGCCGGCAAGTCCATGGCGGACGTGGCCAGCGCCAACGGCCTTGAGG
TCAAGACCGCCAGCGGCCTGAAACGCGGCCGCGCCGAGGGCGACTTCACCACCGAAGCGGTGGCCAAGGTGTTCGGCGTG
GCGCTCAACGGCTATGGCGTCGCACTCGGCACCGCCAATGCCGAGCAACTGGTGTTCCAGGTGACGAAGGTGGAATCGCC
GCCGAGCGCCAACGACATCCGGATCGACAACCAGCTCCAGCAGCAGGTGGAGAACGACATTCTCCAGCAGTATCTGACAG
CCCTGCAGGGCCAGATCGGCCTCACCATCAACCAGCGCGCGGTGCAGCAGGCGGTCGGCGCCAATCAGGTCAACTGA

Upstream 100 bases:

>100_bases
AAACCGTGACCGCAAAAAGGCTGGTAGCAGGGGGCGCGAGCGCCGTTGCGGCGGCGGGTCCCCCTCCCTATGATGCGCGC
CTTCCGCGCCGGCCCTGCCG

Downstream 100 bases:

>100_bases
GGGAGCGTGGCATGAGCGCACCGACCTCGTTCGACGGCTTCGCCGCCCGCTACGCGCGGGGCGAGGCCCAGGTAGTCAGC
ACCACGCTGGTCGCCGACCT

Product: peptidyl-prolyl cis-trans isomerase domain-containing protein

Products: NA

Alternate protein names: PPIase D; Rotamase D [H]

Number of amino acids: Translated: 638; Mature: 638

Protein sequence:

>638_residues
MLLEPDRTMVLQNLRKGASGLIAKVFLLVLTVSFVLWGISGVFTNYSTGTVAEIGGTQISTDAYRQQYLDQIQRIGRQAG
RAITPDQARAFGFDRQVLNQMITEATLDEAARKLGLGMSDALIADSIRDNPALRPPGATAFDPAYFQQLLQANGLTEQRF
LASERKRVLRQQLIESLGGARAPEVLKTAVHSFENEERAVSYLDVTSSSVPAPAAPTDEQLKAYYDGHKVVFRAPEYRKL
TLLVLTPATLAPWIQISDADAKAAYDRNAARFGTPEQRDVQQIVFPSEADAKAALDKIKGGTSFADIAKARGLSDKDTNL
GLVAKSAIIDPKVADAAFALPADGTSDPVQGRFGYALVHVTTIVPATVKPFAEVEAGLRRDLALERARRELLDKHDAIED
ERSSGASLSETAQKLGLTPEVVDAVDRSGREPSGAEVTDIPDRVNVLSAAFSSRPGVDNDPIQLAQNGGYVWFDVNEVTP
SRERPFDEVREQVASRWSEDEVVRAVEAKAKGLLTELEAGKSMADVASANGLEVKTASGLKRGRAEGDFTTEAVAKVFGV
ALNGYGVALGTANAEQLVFQVTKVESPPSANDIRIDNQLQQQVENDILQQYLTALQGQIGLTINQRAVQQAVGANQVN

Sequences:

>Translated_638_residues
MLLEPDRTMVLQNLRKGASGLIAKVFLLVLTVSFVLWGISGVFTNYSTGTVAEIGGTQISTDAYRQQYLDQIQRIGRQAG
RAITPDQARAFGFDRQVLNQMITEATLDEAARKLGLGMSDALIADSIRDNPALRPPGATAFDPAYFQQLLQANGLTEQRF
LASERKRVLRQQLIESLGGARAPEVLKTAVHSFENEERAVSYLDVTSSSVPAPAAPTDEQLKAYYDGHKVVFRAPEYRKL
TLLVLTPATLAPWIQISDADAKAAYDRNAARFGTPEQRDVQQIVFPSEADAKAALDKIKGGTSFADIAKARGLSDKDTNL
GLVAKSAIIDPKVADAAFALPADGTSDPVQGRFGYALVHVTTIVPATVKPFAEVEAGLRRDLALERARRELLDKHDAIED
ERSSGASLSETAQKLGLTPEVVDAVDRSGREPSGAEVTDIPDRVNVLSAAFSSRPGVDNDPIQLAQNGGYVWFDVNEVTP
SRERPFDEVREQVASRWSEDEVVRAVEAKAKGLLTELEAGKSMADVASANGLEVKTASGLKRGRAEGDFTTEAVAKVFGV
ALNGYGVALGTANAEQLVFQVTKVESPPSANDIRIDNQLQQQVENDILQQYLTALQGQIGLTINQRAVQQAVGANQVN
>Mature_638_residues
MLLEPDRTMVLQNLRKGASGLIAKVFLLVLTVSFVLWGISGVFTNYSTGTVAEIGGTQISTDAYRQQYLDQIQRIGRQAG
RAITPDQARAFGFDRQVLNQMITEATLDEAARKLGLGMSDALIADSIRDNPALRPPGATAFDPAYFQQLLQANGLTEQRF
LASERKRVLRQQLIESLGGARAPEVLKTAVHSFENEERAVSYLDVTSSSVPAPAAPTDEQLKAYYDGHKVVFRAPEYRKL
TLLVLTPATLAPWIQISDADAKAAYDRNAARFGTPEQRDVQQIVFPSEADAKAALDKIKGGTSFADIAKARGLSDKDTNL
GLVAKSAIIDPKVADAAFALPADGTSDPVQGRFGYALVHVTTIVPATVKPFAEVEAGLRRDLALERARRELLDKHDAIED
ERSSGASLSETAQKLGLTPEVVDAVDRSGREPSGAEVTDIPDRVNVLSAAFSSRPGVDNDPIQLAQNGGYVWFDVNEVTP
SRERPFDEVREQVASRWSEDEVVRAVEAKAKGLLTELEAGKSMADVASANGLEVKTASGLKRGRAEGDFTTEAVAKVFGV
ALNGYGVALGTANAEQLVFQVTKVESPPSANDIRIDNQLQQQVENDILQQYLTALQGQIGLTINQRAVQQAVGANQVN

Specific function: PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=562, Percent_Identity=25.4448398576512, Blast_Score=153, Evalue=4e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 68868; Mature: 68868

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLEPDRTMVLQNLRKGASGLIAKVFLLVLTVSFVLWGISGVFTNYSTGTVAEIGGTQIS
CCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCC
TDAYRQQYLDQIQRIGRQAGRAITPDQARAFGFDRQVLNQMITEATLDEAARKLGLGMSD
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHH
ALIADSIRDNPALRPPGATAFDPAYFQQLLQANGLTEQRFLASERKRVLRQQLIESLGGA
HHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCC
RAPEVLKTAVHSFENEERAVSYLDVTSSSVPAPAAPTDEQLKAYYDGHKVVFRAPEYRKL
CCHHHHHHHHHHHCCHHHHHHHEECCCCCCCCCCCCCHHHHHHHHCCCEEEEECCCCCEE
TLLVLTPATLAPWIQISDADAKAAYDRNAARFGTPEQRDVQQIVFPSEADAKAALDKIKG
EEEEEECCCCCCCEEEECCCHHHHHCCCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHCC
GTSFADIAKARGLSDKDTNLGLVAKSAIIDPKVADAAFALPADGTSDPVQGRFGYALVHV
CCHHHHHHHHCCCCCCCCCCCCEEHHHHCCCCCCCCEEECCCCCCCCCCCCCHHHHHHHH
TTIVPATVKPFAEVEAGLRRDLALERARRELLDKHDAIEDERSSGASLSETAQKLGLTPE
HHHCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHCCCHH
VVDAVDRSGREPSGAEVTDIPDRVNVLSAAFSSRPGVDNDPIQLAQNGGYVWFDVNEVTP
HHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHCCCCCEEEEECCCCCC
SRERPFDEVREQVASRWSEDEVVRAVEAKAKGLLTELEAGKSMADVASANGLEVKTASGL
CCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCEEECHHHH
KRGRAEGDFTTEAVAKVFGVALNGYGVALGTANAEQLVFQVTKVESPPSANDIRIDNQLQ
HHCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHCCCCCCCCCEEECHHHH
QQVENDILQQYLTALQGQIGLTINQRAVQQAVGANQVN
HHHHHHHHHHHHHHHCCCCCCEECHHHHHHHHCCCCCC
>Mature Secondary Structure
MLLEPDRTMVLQNLRKGASGLIAKVFLLVLTVSFVLWGISGVFTNYSTGTVAEIGGTQIS
CCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCC
TDAYRQQYLDQIQRIGRQAGRAITPDQARAFGFDRQVLNQMITEATLDEAARKLGLGMSD
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHH
ALIADSIRDNPALRPPGATAFDPAYFQQLLQANGLTEQRFLASERKRVLRQQLIESLGGA
HHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCC
RAPEVLKTAVHSFENEERAVSYLDVTSSSVPAPAAPTDEQLKAYYDGHKVVFRAPEYRKL
CCHHHHHHHHHHHCCHHHHHHHEECCCCCCCCCCCCCHHHHHHHHCCCEEEEECCCCCEE
TLLVLTPATLAPWIQISDADAKAAYDRNAARFGTPEQRDVQQIVFPSEADAKAALDKIKG
EEEEEECCCCCCCEEEECCCHHHHHCCCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHCC
GTSFADIAKARGLSDKDTNLGLVAKSAIIDPKVADAAFALPADGTSDPVQGRFGYALVHV
CCHHHHHHHHCCCCCCCCCCCCEEHHHHCCCCCCCCEEECCCCCCCCCCCCCHHHHHHHH
TTIVPATVKPFAEVEAGLRRDLALERARRELLDKHDAIEDERSSGASLSETAQKLGLTPE
HHHCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHCCCHH
VVDAVDRSGREPSGAEVTDIPDRVNVLSAAFSSRPGVDNDPIQLAQNGGYVWFDVNEVTP
HHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHCCCCCEEEEECCCCCC
SRERPFDEVREQVASRWSEDEVVRAVEAKAKGLLTELEAGKSMADVASANGLEVKTASGL
CCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCEEECHHHH
KRGRAEGDFTTEAVAKVFGVALNGYGVALGTANAEQLVFQVTKVESPPSANDIRIDNQLQ
HHCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHCCCCCCCCCEEECHHHH
QQVENDILQQYLTALQGQIGLTINQRAVQQAVGANQVN
HHHHHHHHHHHHHHHCCCCCCEECHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]