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The map label for this gene is oac3 [H]

Identifier: 158423455

GI number: 158423455

Start: 2096029

End: 2096904

Strand: Reverse

Name: oac3 [H]

Synonym: AZC_1831

Alternate gene names: 158423455

Gene position: 2096904-2096029 (Counterclockwise)

Preceding gene: 158423456

Following gene: 158423454

Centisome position: 39.05

GC content: 64.5

Gene sequence:

>876_bases
GTGAAAGGCATCATACTCGCCGGAGGTTCCGGCACCCGTCTCCACCCCATCACGCTCGTCGTGTCCAAGCAGCTGCTGCC
GGTCTACGACAAGCCGATGATCTATTACCCCCTGTGCACCCTGATGATGGCGGGCATCCGGGACATCCTGATCATCACCA
CGCCACATGACAGCGAGCTGTTCCAGAAGCTGCTGAAGGACGGCAGCCAGTTCGGCCTGAACATTTCCTATGCGGTGCAG
CCCTCTCCGCGCGGTCTCGCGGACGCCTTCATCGTCGGCCGCGAGTTCGTCGGCAATGACCGGGTGGCGCTGGTGCTGGG
CGACAACCTGTTCTTCGGCCACGGCCTGCCGGAATTGCTCAAGACCGCGCAGGCGCGCGAGACCGGCGCGACCGTCTTCG
GCTATCCCGTGACCGATCCCGAGCGCTACGGCGTCGTCGAGATGGACGAGACCGGCAAGGTGCTCTCCCTCGAAGAGAAG
CCGCTGAAGCCCAAGTCCAACCTCGCGGTGACCGGCCTTTATTTCTACGACAACCGCGTCGTGGACATCGCCGCCAATCT
CGCGCCCTCGCCGCGGGGCGAGATCGAGATCACCGACGTGAACAAGGCCTATCTCGACCTCGGCGAGCTCAATGTGAGCA
TCATGGGCCGGGGCTTTGCCTGGCTCGACACCGGCACGCCGGCCTCGCTGGTGGAAGCCGCACAGTTCGTGCAGATCCTC
GAGCAGCGTCAGGGCCTGCGTATTTCCTCGCCCGAGGAAATCGCCTTCCGCTCCGGCTTCATCAGCCGCGAGCAACTGGC
CAAGCTCGCGCAGGAGCAGGCGAAGTCCACCTACGGCCAGTATCTCGGCAAGCTCGCCTCCGGCGCCCTCCTCTGA

Upstream 100 bases:

>100_bases
GCCTGTTCGAGCGGACATTCCACTTCCGCGCCGCGCCCTGGCAGCAGCGCACGGTCGAGGTGGTGGACACGCTGCTCGCC
AAGAGCCCCGTGGAGGCATC

Downstream 100 bases:

>100_bases
CGGAGCCTGCCCGGCTCGGGCGCGGCCCGCACCCCAACGATCACCCCCGGCGGCCTTCGCCGGGGCAGCATGAAAGAAGC
CGCCCGTGGGCCCGATCCTC

Product: glucose-1-phosphate thymidylyltransferase

Products: NA

Alternate protein names: G1P-TT 1; dTDP-glucose pyrophosphorylase 1; dTDP-glucose synthase 1 [H]

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MKGIILAGGSGTRLHPITLVVSKQLLPVYDKPMIYYPLCTLMMAGIRDILIITTPHDSELFQKLLKDGSQFGLNISYAVQ
PSPRGLADAFIVGREFVGNDRVALVLGDNLFFGHGLPELLKTAQARETGATVFGYPVTDPERYGVVEMDETGKVLSLEEK
PLKPKSNLAVTGLYFYDNRVVDIAANLAPSPRGEIEITDVNKAYLDLGELNVSIMGRGFAWLDTGTPASLVEAAQFVQIL
EQRQGLRISSPEEIAFRSGFISREQLAKLAQEQAKSTYGQYLGKLASGALL

Sequences:

>Translated_291_residues
MKGIILAGGSGTRLHPITLVVSKQLLPVYDKPMIYYPLCTLMMAGIRDILIITTPHDSELFQKLLKDGSQFGLNISYAVQ
PSPRGLADAFIVGREFVGNDRVALVLGDNLFFGHGLPELLKTAQARETGATVFGYPVTDPERYGVVEMDETGKVLSLEEK
PLKPKSNLAVTGLYFYDNRVVDIAANLAPSPRGEIEITDVNKAYLDLGELNVSIMGRGFAWLDTGTPASLVEAAQFVQIL
EQRQGLRISSPEEIAFRSGFISREQLAKLAQEQAKSTYGQYLGKLASGALL
>Mature_291_residues
MKGIILAGGSGTRLHPITLVVSKQLLPVYDKPMIYYPLCTLMMAGIRDILIITTPHDSELFQKLLKDGSQFGLNISYAVQ
PSPRGLADAFIVGREFVGNDRVALVLGDNLFFGHGLPELLKTAQARETGATVFGYPVTDPERYGVVEMDETGKVLSLEEK
PLKPKSNLAVTGLYFYDNRVVDIAANLAPSPRGEIEITDVNKAYLDLGELNVSIMGRGFAWLDTGTPASLVEAAQFVQIL
EQRQGLRISSPEEIAFRSGFISREQLAKLAQEQAKSTYGQYLGKLASGALL

Specific function: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis [H]

COG id: COG1209

COG function: function code M; dTDP-glucose pyrophosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucose-1-phosphate thymidylyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI11761621, Length=258, Percent_Identity=27.1317829457364, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI11761619, Length=258, Percent_Identity=27.1317829457364, Blast_Score=79, Evalue=6e-15,
Organism=Escherichia coli, GI1788351, Length=288, Percent_Identity=67.0138888888889, Blast_Score=412, Evalue=1e-117,
Organism=Escherichia coli, GI1790224, Length=285, Percent_Identity=62.1052631578947, Blast_Score=367, Evalue=1e-103,
Organism=Escherichia coli, GI1787488, Length=239, Percent_Identity=28.0334728033473, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI133931050, Length=183, Percent_Identity=26.2295081967213, Blast_Score=81, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6320148, Length=254, Percent_Identity=27.9527559055118, Blast_Score=89, Evalue=8e-19,
Organism=Drosophila melanogaster, GI21355443, Length=252, Percent_Identity=25.3968253968254, Blast_Score=81, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24644084, Length=252, Percent_Identity=25.3968253968254, Blast_Score=81, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005907
- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.24 [H]

Molecular weight: Translated: 31736; Mature: 31736

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGIILAGGSGTRLHPITLVVSKQLLPVYDKPMIYYPLCTLMMAGIRDILIITTPHDSEL
CCCEEEECCCCCEEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCHHH
FQKLLKDGSQFGLNISYAVQPSPRGLADAFIVGREFVGNDRVALVLGDNLFFGHGLPELL
HHHHHHCCHHHCCEEEEEECCCCCCHHHHHHHHHHHCCCCEEEEEEECCEEECCCHHHHH
KTAQARETGATVFGYPVTDPERYGVVEMDETGKVLSLEEKPLKPKSNLAVTGLYFYDNRV
HHHHHHHCCCEEEECCCCCCCCCCEEEECCCCCEEEECCCCCCCCCCEEEEEEEEECCEE
VDIAANLAPSPRGEIEITDVNKAYLDLGELNVSIMGRGFAWLDTGTPASLVEAAQFVQIL
EEEEECCCCCCCCCEEEEECCHHHHHHHHEEEEEEECCEEEEECCCCHHHHHHHHHHHHH
EQRQGLRISSPEEIAFRSGFISREQLAKLAQEQAKSTYGQYLGKLASGALL
HHHCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKGIILAGGSGTRLHPITLVVSKQLLPVYDKPMIYYPLCTLMMAGIRDILIITTPHDSEL
CCCEEEECCCCCEEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCHHH
FQKLLKDGSQFGLNISYAVQPSPRGLADAFIVGREFVGNDRVALVLGDNLFFGHGLPELL
HHHHHHCCHHHCCEEEEEECCCCCCHHHHHHHHHHHCCCCEEEEEEECCEEECCCHHHHH
KTAQARETGATVFGYPVTDPERYGVVEMDETGKVLSLEEKPLKPKSNLAVTGLYFYDNRV
HHHHHHHCCCEEEECCCCCCCCCCEEEECCCCCEEEECCCCCCCCCCEEEEEEEEECCEE
VDIAANLAPSPRGEIEITDVNKAYLDLGELNVSIMGRGFAWLDTGTPASLVEAAQFVQIL
EEEEECCCCCCCCCEEEEECCHHHHHHHHEEEEEEECCEEEEECCCCHHHHHHHHHHHHH
EQRQGLRISSPEEIAFRSGFISREQLAKLAQEQAKSTYGQYLGKLASGALL
HHHCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7517391; 9097040; 9278503; 7517390 [H]