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The map label for this gene is gmhB [H]

Identifier: 158423454

GI number: 158423454

Start: 2094837

End: 2095880

Strand: Reverse

Name: gmhB [H]

Synonym: AZC_1830

Alternate gene names: 158423454

Gene position: 2095880-2094837 (Counterclockwise)

Preceding gene: 158423455

Following gene: 158423453

Centisome position: 39.03

GC content: 70.5

Gene sequence:

>1044_bases
ATGGGCGACGGAGCGTTTTCCCCGCCAACGCAGGCGGTGATCCCATGGGGCTTTGCCCGGGAGGACGCCGCGGGTCTCGC
CCGCGCCCTCACCGACGCCGCCCGCTTCGGCTTCACCCGCCTTCTGGTGCCTGTGCCGCCGGACCACGCCGGACGGGCCC
ATGCGATCATCGCGGCCCTGCCGCCCCTGCCCCATCTGGCGCGGATCGCCGTCCACGCGCTCGACAGGCTGAGCGGTCTC
TCCGCTTTGCCGCTCGATCGCCGCTTCCTCTTGGTCGATCCCGGCCGCGTGATCCAGGCCAACTGGCTCGATCTGTTCGC
AACGCCCGCCCAAGCCATCGTGGCGGGGACCGACGGCGCGGCGCCGGCAGGCCTCGCGGGCCTCGACCGCGACCTCCTGC
CCGCGCTCTCCGGTGCGGATGCGCCACGAGATGTATTGGCCCGTCTCGGCACCGTCTACGGTGTCGGCCGTCTCCGGCTG
CCGGCAGATGCCGTCTGCGACAGCCGTCCGGCGACCCCAGCGCGTCCGGAGCGCCCCGCCCTCTTCCTCGACCGCGACGG
CACGTTGAACGAGGACTATGGCTATGTGAGCGACCCCGCCCGGCTCGTCCTGTTGCCCGGCGCGGCGCAGGCGGTGAAGC
GGGCCAACGATCTCGGCTGGAACGTCTTTCTCGTCACCAACCAGTCCGGCATCGGGCGCGGCTATTATGCGGAGGCCGAT
GCCATTGCCTGCAATGCGGCACTCCAGGAGATGCTGCGCGCCCATGGCGCCCATCTGGACGACATCCGCTATGCCGCCGA
CCATCCGGAGGCGGAGGAGCCGCGCTATCGCATCGCCACCGGCTGGCGCAAACCCGAGCCGGGCATGTTGATCGACCTCA
TGGCGCACTGGCCCACAGTGCGCGAGATCAGCCTCATGGTGGGCGACAAGGACAGCGATATCGCTGCCGGAGCGGCAGCG
GGTGTGCGCGGCCTCCTCTTCACGGGCGGCGATCTGGATGCCCTGGTGGCGTCGCATCTGACCGGCGCTCCTTGCAGCGG
TTAA

Upstream 100 bases:

>100_bases
GGCGGCCTTCGCCGGGGCAGCATGAAAGAAGCCGCCCGTGGGCCCGATCCTCCGCGAACCGTTCCTATCGCCGCAGGCGC
GGCAGCCGGGCGCCTGAGCC

Downstream 100 bases:

>100_bases
AAAGACGCGCCGCCGCAGTGCAGCGCGGGAAATACGTGCTATAGAGTGAAAGCAATGCTTTCACAGTGCACGGCCGTGAT
TGGGTGTGCGCCAGACGGAG

Product: histidinol-phosphate phosphatase

Products: NA

Alternate protein names: D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [H]

Number of amino acids: Translated: 347; Mature: 346

Protein sequence:

>347_residues
MGDGAFSPPTQAVIPWGFAREDAAGLARALTDAARFGFTRLLVPVPPDHAGRAHAIIAALPPLPHLARIAVHALDRLSGL
SALPLDRRFLLVDPGRVIQANWLDLFATPAQAIVAGTDGAAPAGLAGLDRDLLPALSGADAPRDVLARLGTVYGVGRLRL
PADAVCDSRPATPARPERPALFLDRDGTLNEDYGYVSDPARLVLLPGAAQAVKRANDLGWNVFLVTNQSGIGRGYYAEAD
AIACNAALQEMLRAHGAHLDDIRYAADHPEAEEPRYRIATGWRKPEPGMLIDLMAHWPTVREISLMVGDKDSDIAAGAAA
GVRGLLFTGGDLDALVASHLTGAPCSG

Sequences:

>Translated_347_residues
MGDGAFSPPTQAVIPWGFAREDAAGLARALTDAARFGFTRLLVPVPPDHAGRAHAIIAALPPLPHLARIAVHALDRLSGL
SALPLDRRFLLVDPGRVIQANWLDLFATPAQAIVAGTDGAAPAGLAGLDRDLLPALSGADAPRDVLARLGTVYGVGRLRL
PADAVCDSRPATPARPERPALFLDRDGTLNEDYGYVSDPARLVLLPGAAQAVKRANDLGWNVFLVTNQSGIGRGYYAEAD
AIACNAALQEMLRAHGAHLDDIRYAADHPEAEEPRYRIATGWRKPEPGMLIDLMAHWPTVREISLMVGDKDSDIAAGAAA
GVRGLLFTGGDLDALVASHLTGAPCSG
>Mature_346_residues
GDGAFSPPTQAVIPWGFAREDAAGLARALTDAARFGFTRLLVPVPPDHAGRAHAIIAALPPLPHLARIAVHALDRLSGLS
ALPLDRRFLLVDPGRVIQANWLDLFATPAQAIVAGTDGAAPAGLAGLDRDLLPALSGADAPRDVLARLGTVYGVGRLRLP
ADAVCDSRPATPARPERPALFLDRDGTLNEDYGYVSDPARLVLLPGAAQAVKRANDLGWNVFLVTNQSGIGRGYYAEADA
IACNAALQEMLRAHGAHLDDIRYAADHPEAEEPRYRIATGWRKPEPGMLIDLMAHWPTVREISLMVGDKDSDIAAGAAAG
VRGLLFTGGDLDALVASHLTGAPCSG

Specific function: Converts the D-glycero-alpha-D-manno-heptose 1,7- bisphosphate intermediate into D-glycero-alpha-D-manno-heptose 1- phosphate by removing the phosphate group at the C-7 position [H]

COG id: COG0241

COG function: function code E; Histidinol phosphatase and related phosphatases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gmhB family [H]

Homologues:

Organism=Escherichia coli, GI1786399, Length=153, Percent_Identity=37.2549019607843, Blast_Score=99, Evalue=5e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR006549
- InterPro:   IPR004446
- InterPro:   IPR006543 [H]

Pfam domain/function: NA

EC number: 3.1.1.-

Molecular weight: Translated: 36498; Mature: 36367

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGDGAFSPPTQAVIPWGFAREDAAGLARALTDAARFGFTRLLVPVPPDHAGRAHAIIAAL
CCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCEEEEEEC
PPLPHLARIAVHALDRLSGLSALPLDRRFLLVDPGRVIQANWLDLFATPAQAIVAGTDGA
CCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCEEEECHHHHHCCCCCEEEECCCCC
APAGLAGLDRDLLPALSGADAPRDVLARLGTVYGVGRLRLPADAVCDSRPATPARPERPA
CCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHCCCEECCCHHHHCCCCCCCCCCCCCCE
LFLDRDGTLNEDYGYVSDPARLVLLPGAAQAVKRANDLGWNVFLVTNQSGIGRGYYAEAD
EEEECCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHCCEEEEEEECCCCCCCCEECCCH
AIACNAALQEMLRAHGAHLDDIRYAADHPEAEEPRYRIATGWRKPEPGMLIDLMAHWPTV
HHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCEEEECCCCCCCCCEEEEHHHCCCCC
REISLMVGDKDSDIAAGAAAGVRGLLFTGGDLDALVASHLTGAPCSG
EEEEEEECCCCCCHHHHHHHCCCEEEEECCCHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
GDGAFSPPTQAVIPWGFAREDAAGLARALTDAARFGFTRLLVPVPPDHAGRAHAIIAAL
CCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCEEEEEEC
PPLPHLARIAVHALDRLSGLSALPLDRRFLLVDPGRVIQANWLDLFATPAQAIVAGTDGA
CCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCEEEECHHHHHCCCCCEEEECCCCC
APAGLAGLDRDLLPALSGADAPRDVLARLGTVYGVGRLRLPADAVCDSRPATPARPERPA
CCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHCCCEECCCHHHHCCCCCCCCCCCCCCE
LFLDRDGTLNEDYGYVSDPARLVLLPGAAQAVKRANDLGWNVFLVTNQSGIGRGYYAEAD
EEEECCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHCCEEEEEEECCCCCCCCEECCCH
AIACNAALQEMLRAHGAHLDDIRYAADHPEAEEPRYRIATGWRKPEPGMLIDLMAHWPTV
HHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCEEEECCCCCCCCCEEEEHHHCCCCC
REISLMVGDKDSDIAAGAAAGVRGLLFTGGDLDALVASHLTGAPCSG
EEEEEEECCCCCCHHHHHHHCCCEEEEECCCHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11373120; 12101286 [H]