Click here to switch to the map view.

The map label for this gene is nuoC

Identifier: 158423293

GI number: 158423293

Start: 1910001

End: 1910636

Strand: Direct

Name: nuoC

Synonym: AZC_1669

Alternate gene names: 158423293

Gene position: 1910001-1910636 (Clockwise)

Preceding gene: 158423292

Following gene: 158423294

Centisome position: 35.57

GC content: 66.51

Gene sequence:

>636_bases
ATGGACGAGACCCTGAAGGATCTGGCGGCTCACGTGACGGGCGCACTGCCCGGCGCGGTGGTGGCCCACAAGATCGCCTA
TGGCGAGCTGACGCTCGAAACGACGCCGGACCACATCCTCAAGCTGGCGACGTTCCTGCGTGACGATCCGTCCTGCCTGT
TCACCTGCATCGTGGATGTCTGCGGCGCCGACTATCCGGCCCGCGAGCAGCGTTTCGAGGTGGTCTACCACCTGCTCTCC
CTGAAGCAGAACGCCCGCGTGCGGGTGAAACTGTCGGCGGGCGAGGAGACGCTGGTGCCGTCCGTGACCGGCATCTGGCC
GGGTGCGAACTGGTTCGAGCGCGAGGCCTACGACCTCTATGGCATCCTGTTCACGGGCCACCCGGAACTGCGCCGCCTGC
TCACCGACTACGGCTTCGACGGCCACCCGCTGCGCAAGGACTTCCCGCTCACCGGCTTCGTCGAGGTGCGCTATGACGAC
GAGCTGAAGCGCGTCGTCTATGAGCCCGTGCGGCTCGCGCAGGAATTCCGCAACTTCGATTTCCTCTCGCCCTGGGAAGG
TGTGGAATACATCCTGCCCGGCGACGAGAAGGCGTCATCCCAGCCCGGCGCGCCTGCCGCGCCCAAGGCGAGCTGA

Upstream 100 bases:

>100_bases
GGAAGCTCTGCTCTACGGCGTGCTTCTGCTGCAGCGGAAGATCCGCCGCACCGGCACCATCGAACGCTGAACGGCCGCAT
CGGGCGACAGGAACTGGCGC

Downstream 100 bases:

>100_bases
AGGAGCGCGCCATGGCCCATACCCTGGACAGCCAGCAGCCGGCGGTGCCGGTCCGCAATTTCCAGATCAACTTCGGTCCC
CAGCATCCGGCCGCCCACGG

Product: NADH-ubiquinone dehydrogenase chain C 1

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C; NDH-1 subunit C

Number of amino acids: Translated: 211; Mature: 211

Protein sequence:

>211_residues
MDETLKDLAAHVTGALPGAVVAHKIAYGELTLETTPDHILKLATFLRDDPSCLFTCIVDVCGADYPAREQRFEVVYHLLS
LKQNARVRVKLSAGEETLVPSVTGIWPGANWFEREAYDLYGILFTGHPELRRLLTDYGFDGHPLRKDFPLTGFVEVRYDD
ELKRVVYEPVRLAQEFRNFDFLSPWEGVEYILPGDEKASSQPGAPAAPKAS

Sequences:

>Translated_211_residues
MDETLKDLAAHVTGALPGAVVAHKIAYGELTLETTPDHILKLATFLRDDPSCLFTCIVDVCGADYPAREQRFEVVYHLLS
LKQNARVRVKLSAGEETLVPSVTGIWPGANWFEREAYDLYGILFTGHPELRRLLTDYGFDGHPLRKDFPLTGFVEVRYDD
ELKRVVYEPVRLAQEFRNFDFLSPWEGVEYILPGDEKASSQPGAPAAPKAS
>Mature_211_residues
MDETLKDLAAHVTGALPGAVVAHKIAYGELTLETTPDHILKLATFLRDDPSCLFTCIVDVCGADYPAREQRFEVVYHLLS
LKQNARVRVKLSAGEETLVPSVTGIWPGANWFEREAYDLYGILFTGHPELRRLLTDYGFDGHPLRKDFPLTGFVEVRYDD
ELKRVVYEPVRLAQEFRNFDFLSPWEGVEYILPGDEKASSQPGAPAAPKAS

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family

Homologues:

Organism=Homo sapiens, GI4758788, Length=186, Percent_Identity=50, Blast_Score=201, Evalue=4e-52,
Organism=Escherichia coli, GI145693162, Length=186, Percent_Identity=31.1827956989247, Blast_Score=99, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI71990788, Length=185, Percent_Identity=49.7297297297297, Blast_Score=191, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI32563621, Length=185, Percent_Identity=49.7297297297297, Blast_Score=191, Evalue=3e-49,
Organism=Drosophila melanogaster, GI24656494, Length=183, Percent_Identity=50.8196721311475, Blast_Score=196, Evalue=1e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUOC_AZOC5 (A8I3Y9)

Other databases:

- EMBL:   AP009384
- RefSeq:   YP_001524585.1
- ProteinModelPortal:   A8I3Y9
- SMR:   A8I3Y9
- GeneID:   5687779
- GenomeReviews:   AP009384_GR
- KEGG:   azc:AZC_1669
- HOGENOM:   HBG727675
- OMA:   VVYEPVR
- ProtClustDB:   CLSK980354
- BioCyc:   ACAU438753:AZC_1669-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_01357
- InterPro:   IPR010218
- InterPro:   IPR001268
- InterPro:   IPR020396
- ProDom:   PD001581
- TIGRFAMs:   TIGR01961

Pfam domain/function: PF00329 Complex1_30kDa

EC number: =1.6.99.5

Molecular weight: Translated: 23654; Mature: 23654

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: PS00542 COMPLEX1_30K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDETLKDLAAHVTGALPGAVVAHKIAYGELTLETTPDHILKLATFLRDDPSCLFTCIVDV
CCHHHHHHHHHHHCCCCHHHHHHHHHHCEEEEECCHHHHHHHHHHHCCCHHHHHHHHHHH
CGADYPAREQRFEVVYHLLSLKQNARVRVKLSAGEETLVPSVTGIWPGANWFEREAYDLY
HCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHEEE
GILFTGHPELRRLLTDYGFDGHPLRKDFPLTGFVEVRYDDELKRVVYEPVRLAQEFRNFD
EEEEECCHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHCCC
FLSPWEGVEYILPGDEKASSQPGAPAAPKAS
CCCCCCCCEEEECCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MDETLKDLAAHVTGALPGAVVAHKIAYGELTLETTPDHILKLATFLRDDPSCLFTCIVDV
CCHHHHHHHHHHHCCCCHHHHHHHHHHCEEEEECCHHHHHHHHHHHCCCHHHHHHHHHHH
CGADYPAREQRFEVVYHLLSLKQNARVRVKLSAGEETLVPSVTGIWPGANWFEREAYDLY
HCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHEEE
GILFTGHPELRRLLTDYGFDGHPLRKDFPLTGFVEVRYDDELKRVVYEPVRLAQEFRNFD
EEEEECCHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHCCC
FLSPWEGVEYILPGDEKASSQPGAPAAPKAS
CCCCCCCCEEEECCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA