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The map label for this gene is nuoD

Identifier: 158423294

GI number: 158423294

Start: 1910648

End: 1911856

Strand: Direct

Name: nuoD

Synonym: AZC_1670

Alternate gene names: 158423294

Gene position: 1910648-1911856 (Clockwise)

Preceding gene: 158423293

Following gene: 158423295

Centisome position: 35.58

GC content: 65.18

Gene sequence:

>1209_bases
ATGGCCCATACCCTGGACAGCCAGCAGCCGGCGGTGCCGGTCCGCAATTTCCAGATCAACTTCGGTCCCCAGCATCCGGC
CGCCCACGGCGTGCTGCGCATGGTGCTGGAGCTGAACGGCGAGGTGGTGGAACGCGTCGATCCGCATATCGGCCTGCTGC
ATCGCGGCACCGAGAAGCTGATCGAGGCCAAGACCTATCTCCAGGCCGTGCCCTATTTCGACCGGCTCGACTATTGCGCG
CCGATGAATCAGGAGCACGCCTTCTGCCTTGCGGTGGAGCGCCTTGCGGGCATCGAGGTGCCCAAGCGCGGCCAGCTTAT
CCGCGTGCTCTATTCCGAGATCGGGCGCCTGCTCTCGCACCTTCTCAACGTGACCACGTTCGCCATGGACGTGGGCGCGC
TGACCCCGCCGCTGTGGGGCTTCGAGGCCCGCGAAAAGCTCATGATGTTCTATGAGCGCGCCTCGGGCAGCCGCATGCAT
GCGGCCTATTTCCGGCCGGGCGGCGTGCACCAGGATCTGCCGCAGAAGCTGGTCGAGGACATCGGCGAGTTCTGCCGCAC
CTTCCCGAGCCTGCTCGACGACCTCGACGCGCTCGTGACCGGCAACCGTATCTTCAAGCAGCGCACCGTCGACATCGGCG
TCGTGACGCTGGAGGACGCGCTGGCGTGGGGCTTCTCGGGCGTCATGGTGCGCGGCTCCGGCGCGCCGTGGGACCTGCGC
CGCGCGCAGCCCTACGAGTGCTATTCGGAGCTCGACTTCGACATTCCGATCGGCAAGCACGGCGACTGCTACGACCGCTA
TGTGGTCCGCATGGAAGAGATGCGGCAGTCCAACAAGATCATGCTTCAGTGCGTGGACCGCCTCCTGAAGGAGGCCGGCC
CCGTCGCCTCGACGGACCGCAAGGTCTCTCCCCCCAAGCGTGGCGAGATGAAGCGCTCCATGGAAGCGCTTATTCATCAC
TTCAAGCTATACACCGAAGGCTTCCACGTGCCGGAAGGGGAAGTCTATGCGGCGGTGGAAGCGCCGAAGGGGGAATTCGG
CGTTTATCTGGTCGGCGACGGCACCAACAAGCCGTACCGCTGCAAGATCCGCGCTCCCGGCTTCGCGCACCTTCAGTCCA
TGGACTTCCTGTGTCGCGGGCACATGCTCGCCGACGTCTCGGCGGTGCTTGGCTCCCTCGACATCGTGTTCGGGGAGGTG
GATCGGTGA

Upstream 100 bases:

>100_bases
CGCCCTGGGAAGGTGTGGAATACATCCTGCCCGGCGACGAGAAGGCGTCATCCCAGCCCGGCGCGCCTGCCGCGCCCAAG
GCGAGCTGAAGGAGCGCGCC

Downstream 100 bases:

>100_bases
AGGCTTTCGCGCTCGGCATTCTCGCGCTGGCGGCGTCCGCCGGCTTCGCGTCGGCGGCGGACTATCCGACGAAGGCGCCC
ATGAGCATCGAGATCGTGGC

Product: NADH-quinone dehydrogenase chain D 1 protein

Products: NA

Alternate protein names: NADH dehydrogenase I subunit D; NDH-1 subunit D

Number of amino acids: Translated: 402; Mature: 401

Protein sequence:

>402_residues
MAHTLDSQQPAVPVRNFQINFGPQHPAAHGVLRMVLELNGEVVERVDPHIGLLHRGTEKLIEAKTYLQAVPYFDRLDYCA
PMNQEHAFCLAVERLAGIEVPKRGQLIRVLYSEIGRLLSHLLNVTTFAMDVGALTPPLWGFEAREKLMMFYERASGSRMH
AAYFRPGGVHQDLPQKLVEDIGEFCRTFPSLLDDLDALVTGNRIFKQRTVDIGVVTLEDALAWGFSGVMVRGSGAPWDLR
RAQPYECYSELDFDIPIGKHGDCYDRYVVRMEEMRQSNKIMLQCVDRLLKEAGPVASTDRKVSPPKRGEMKRSMEALIHH
FKLYTEGFHVPEGEVYAAVEAPKGEFGVYLVGDGTNKPYRCKIRAPGFAHLQSMDFLCRGHMLADVSAVLGSLDIVFGEV
DR

Sequences:

>Translated_402_residues
MAHTLDSQQPAVPVRNFQINFGPQHPAAHGVLRMVLELNGEVVERVDPHIGLLHRGTEKLIEAKTYLQAVPYFDRLDYCA
PMNQEHAFCLAVERLAGIEVPKRGQLIRVLYSEIGRLLSHLLNVTTFAMDVGALTPPLWGFEAREKLMMFYERASGSRMH
AAYFRPGGVHQDLPQKLVEDIGEFCRTFPSLLDDLDALVTGNRIFKQRTVDIGVVTLEDALAWGFSGVMVRGSGAPWDLR
RAQPYECYSELDFDIPIGKHGDCYDRYVVRMEEMRQSNKIMLQCVDRLLKEAGPVASTDRKVSPPKRGEMKRSMEALIHH
FKLYTEGFHVPEGEVYAAVEAPKGEFGVYLVGDGTNKPYRCKIRAPGFAHLQSMDFLCRGHMLADVSAVLGSLDIVFGEV
DR
>Mature_401_residues
AHTLDSQQPAVPVRNFQINFGPQHPAAHGVLRMVLELNGEVVERVDPHIGLLHRGTEKLIEAKTYLQAVPYFDRLDYCAP
MNQEHAFCLAVERLAGIEVPKRGQLIRVLYSEIGRLLSHLLNVTTFAMDVGALTPPLWGFEAREKLMMFYERASGSRMHA
AYFRPGGVHQDLPQKLVEDIGEFCRTFPSLLDDLDALVTGNRIFKQRTVDIGVVTLEDALAWGFSGVMVRGSGAPWDLRR
AQPYECYSELDFDIPIGKHGDCYDRYVVRMEEMRQSNKIMLQCVDRLLKEAGPVASTDRKVSPPKRGEMKRSMEALIHHF
KLYTEGFHVPEGEVYAAVEAPKGEFGVYLVGDGTNKPYRCKIRAPGFAHLQSMDFLCRGHMLADVSAVLGSLDIVFGEVD
R

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0649

COG function: function code C; NADH:ubiquinone oxidoreductase 49 kD subunit 7

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 49 kDa subunit family

Homologues:

Organism=Homo sapiens, GI4758786, Length=389, Percent_Identity=64.5244215938303, Blast_Score=531, Evalue=1e-151,
Organism=Homo sapiens, GI260898743, Length=383, Percent_Identity=63.7075718015666, Blast_Score=516, Evalue=1e-146,
Organism=Escherichia coli, GI145693162, Length=385, Percent_Identity=39.7402597402597, Blast_Score=299, Evalue=2e-82,
Organism=Escherichia coli, GI1789076, Length=390, Percent_Identity=26.1538461538462, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1788832, Length=386, Percent_Identity=26.1658031088083, Blast_Score=106, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17555284, Length=389, Percent_Identity=60.1542416452442, Blast_Score=503, Evalue=1e-143,
Organism=Caenorhabditis elegans, GI17568379, Length=402, Percent_Identity=58.2089552238806, Blast_Score=500, Evalue=1e-142,
Organism=Drosophila melanogaster, GI24638644, Length=389, Percent_Identity=62.4678663239075, Blast_Score=526, Evalue=1e-150,
Organism=Drosophila melanogaster, GI221459469, Length=388, Percent_Identity=55.4123711340206, Blast_Score=465, Evalue=1e-131,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUOD_AZOC5 (A8I3Z3)

Other databases:

- EMBL:   AP009384
- RefSeq:   YP_001524586.1
- ProteinModelPortal:   A8I3Z3
- SMR:   A8I3Z3
- GeneID:   5687780
- GenomeReviews:   AP009384_GR
- KEGG:   azc:AZC_1670
- HOGENOM:   HBG459705
- OMA:   IFYERAC
- ProtClustDB:   CLSK980353
- BioCyc:   ACAU438753:AZC_1670-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_01358
- InterPro:   IPR010219
- InterPro:   IPR001135
- InterPro:   IPR014029
- InterPro:   IPR022885
- TIGRFAMs:   TIGR01962

Pfam domain/function: PF00346 Complex1_49kDa

EC number: =1.6.99.5

Molecular weight: Translated: 45220; Mature: 45089

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: PS00535 COMPLEX1_49K; PS00503 PECTINESTERASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHTLDSQQPAVPVRNFQINFGPQHPAAHGVLRMVLELNGEVVERVDPHIGLLHRGTEKL
CCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCHHHHHCCCCHHHHHCCHHHH
IEAKTYLQAVPYFDRLDYCAPMNQEHAFCLAVERLAGIEVPKRGQLIRVLYSEIGRLLSH
HHHHHHHHHCCCHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
LLNVTTFAMDVGALTPPLWGFEAREKLMMFYERASGSRMHAAYFRPGGVHQDLPQKLVED
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHH
IGEFCRTFPSLLDDLDALVTGNRIFKQRTVDIGVVTLEDALAWGFSGVMVRGSGAPWDLR
HHHHHHHHHHHHHHHHHHHCCCHHHHHHEEEEEEEEEHHHHHHCCCCEEEECCCCCCCCC
RAQPYECYSELDFDIPIGKHGDCYDRYVVRMEEMRQSNKIMLQCVDRLLKEAGPVASTDR
CCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
KVSPPKRGEMKRSMEALIHHFKLYTEGFHVPEGEVYAAVEAPKGEFGVYLVGDGTNKPYR
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCEEEEEEECCCCCCEE
CKIRAPGFAHLQSMDFLCRGHMLADVSAVLGSLDIVFGEVDR
EEEECCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHEEECCCC
>Mature Secondary Structure 
AHTLDSQQPAVPVRNFQINFGPQHPAAHGVLRMVLELNGEVVERVDPHIGLLHRGTEKL
CCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCHHHHHCCCCHHHHHCCHHHH
IEAKTYLQAVPYFDRLDYCAPMNQEHAFCLAVERLAGIEVPKRGQLIRVLYSEIGRLLSH
HHHHHHHHHCCCHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
LLNVTTFAMDVGALTPPLWGFEAREKLMMFYERASGSRMHAAYFRPGGVHQDLPQKLVED
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHH
IGEFCRTFPSLLDDLDALVTGNRIFKQRTVDIGVVTLEDALAWGFSGVMVRGSGAPWDLR
HHHHHHHHHHHHHHHHHHHCCCHHHHHHEEEEEEEEEHHHHHHCCCCEEEECCCCCCCCC
RAQPYECYSELDFDIPIGKHGDCYDRYVVRMEEMRQSNKIMLQCVDRLLKEAGPVASTDR
CCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
KVSPPKRGEMKRSMEALIHHFKLYTEGFHVPEGEVYAAVEAPKGEFGVYLVGDGTNKPYR
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCEEEEEEECCCCCCEE
CKIRAPGFAHLQSMDFLCRGHMLADVSAVLGSLDIVFGEVDR
EEEECCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA