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The map label for this gene is pabB [H]

Identifier: 158423222

GI number: 158423222

Start: 1823503

End: 1824942

Strand: Reverse

Name: pabB [H]

Synonym: AZC_1598

Alternate gene names: 158423222

Gene position: 1824942-1823503 (Counterclockwise)

Preceding gene: 158423225

Following gene: 158423221

Centisome position: 33.99

GC content: 71.6

Gene sequence:

>1440_bases
ATGTTACGGCACGCGGTGGAATCGCCGCAGCCCGGAGATGCCCCGCCCGTGCACGTGGTCCCCATCGCCTATGGCGATCC
CGTCCGCCTGTTCCGAGCCTTTGCGGACGACCCCATGGCCGCCCTGCTGCACAGCGCGGCGCAGGATGGCGCGCGCGGGC
GCTATTCCTACATCGCCGCCGAACCTTTCCGGGTCATCGTCGCGGACGCCGACGGCGTGCGGGTGGACGGCGCGTCGGTG
GCGGGCGATCCGTTCACCGTTCTGGGCGCGCAGCTCGCCGCCTGTCCGGCACCCGAGGGGCTTGCGCCCGTGCCGTTCGC
CGGCGGCGCGGTCGGTTTCCTCGGTTATGAGCTGGGTCGGCATGTGGAGCGCCTGCCGCCGCCGAAGCCGGGGCTGCCCA
TCCCCCACATGGTGATGGGCCTCTATGACGTGGTGATCGCCTTCGATCATGCGGCGCGGGCGGCCGTCCTGATCTCCACC
GGCCTGCCGGAGATAGCGGCGAACGTTCGCGCGGCACGGGCCAAGGCGCGGGTCGCGCATCTCCTCGCCCGCCTCTCGAA
GGCGCCGGCCGAGGACACGCCGCCGGACATCACAGCCCGCGCGGACTGGACGGCAGAACTCTCGCGCGCCGAGATGGAGG
CCCGCATCGGCCGCACGGTGGACTACATCCACGCGGGCGACATCTTCCAGGCCAACATCACCCAGCGCTTCCTGAGCCGC
CGCCCGGAGGGCCTGTCCGATTACGACCTTTACCGGCGGCTGACCGCCCTCTCGCCCGCCCCCTTCTCGGCCCTGCTCGT
CTGCGGACCGGACCTTGCCCTCATGAGCGCCTCGCCCGAGCGCTTCCTGAAGGTGGCGCCCGATGGCGGCGTGGAGACGC
GGCCCATCAAGGGCACCCGGCCGCGCGGCGGCACGACGGCCGAGGACACGGCCCTCGCCGCCGCGCTTCTCGCCAGCGAG
AAGGACCGGGCCGAGAATCTGATGATCGTGGACCTCATGCGCAACGATCTCGGCCGTGTGTCACGGCTCGGCAGCGTCAC
CGTGCCGGCGCTCTGCGCGCTGGAGACCTTTGCCAGCGTGCATCACCTCGTCTCCGAGGTGCGGAGCGTCCTTGCCCCCG
GCCGCGGGCCGGTGGACCTGCTGCGGGCCTGTTTCCCCGGCGGCTCCATCACTGGGGCGCCCAAGGTGCGGGCCATGGAG
ATCATCCACGAACTGGAGCCCGCGCCGCGCGGGCCCTATTGCGGGAGCGTGGCGTGGATCGGCTTTGACGGCGCCATGGA
TTCCTCCATCGTCATCCGCACGCTGGTGCGCGCGGGCGAAACCCTGGTGGCGCAGGCGGGCGGCGGCATCGTCGCCGACA
GCGACCCAGCGGCGGAATATGAGGAGAGCCTGGTGAAAGTGGCGCCCCTGCTGAAGGCGGCTGCGGGAGAGACGCCATGA

Upstream 100 bases:

>100_bases
GCGTGCTTTAGCATCGGTCCGCCCGGCGCGGCAGGCAACGGGATGCATGGCTTGGCGGGCTGACGTGCGGAGAGGGCTTG
CGCCCGCTACCGCAAGGTGA

Downstream 100 bases:

>100_bases
AGCTGTGGCTGAACGGCGGTCTCGTTGATGCCGCCGCCGCCCGCATCGCCCCCGGCGATCGCGGCTTCACGCTGGGCGAC
GGCCTGTTCGAAACCATCGC

Product: para-aminobenzoate synthase

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 479; Mature: 479

Protein sequence:

>479_residues
MLRHAVESPQPGDAPPVHVVPIAYGDPVRLFRAFADDPMAALLHSAAQDGARGRYSYIAAEPFRVIVADADGVRVDGASV
AGDPFTVLGAQLAACPAPEGLAPVPFAGGAVGFLGYELGRHVERLPPPKPGLPIPHMVMGLYDVVIAFDHAARAAVLIST
GLPEIAANVRAARAKARVAHLLARLSKAPAEDTPPDITARADWTAELSRAEMEARIGRTVDYIHAGDIFQANITQRFLSR
RPEGLSDYDLYRRLTALSPAPFSALLVCGPDLALMSASPERFLKVAPDGGVETRPIKGTRPRGGTTAEDTALAAALLASE
KDRAENLMIVDLMRNDLGRVSRLGSVTVPALCALETFASVHHLVSEVRSVLAPGRGPVDLLRACFPGGSITGAPKVRAME
IIHELEPAPRGPYCGSVAWIGFDGAMDSSIVIRTLVRAGETLVAQAGGGIVADSDPAAEYEESLVKVAPLLKAAAGETP

Sequences:

>Translated_479_residues
MLRHAVESPQPGDAPPVHVVPIAYGDPVRLFRAFADDPMAALLHSAAQDGARGRYSYIAAEPFRVIVADADGVRVDGASV
AGDPFTVLGAQLAACPAPEGLAPVPFAGGAVGFLGYELGRHVERLPPPKPGLPIPHMVMGLYDVVIAFDHAARAAVLIST
GLPEIAANVRAARAKARVAHLLARLSKAPAEDTPPDITARADWTAELSRAEMEARIGRTVDYIHAGDIFQANITQRFLSR
RPEGLSDYDLYRRLTALSPAPFSALLVCGPDLALMSASPERFLKVAPDGGVETRPIKGTRPRGGTTAEDTALAAALLASE
KDRAENLMIVDLMRNDLGRVSRLGSVTVPALCALETFASVHHLVSEVRSVLAPGRGPVDLLRACFPGGSITGAPKVRAME
IIHELEPAPRGPYCGSVAWIGFDGAMDSSIVIRTLVRAGETLVAQAGGGIVADSDPAAEYEESLVKVAPLLKAAAGETP
>Mature_479_residues
MLRHAVESPQPGDAPPVHVVPIAYGDPVRLFRAFADDPMAALLHSAAQDGARGRYSYIAAEPFRVIVADADGVRVDGASV
AGDPFTVLGAQLAACPAPEGLAPVPFAGGAVGFLGYELGRHVERLPPPKPGLPIPHMVMGLYDVVIAFDHAARAAVLIST
GLPEIAANVRAARAKARVAHLLARLSKAPAEDTPPDITARADWTAELSRAEMEARIGRTVDYIHAGDIFQANITQRFLSR
RPEGLSDYDLYRRLTALSPAPFSALLVCGPDLALMSASPERFLKVAPDGGVETRPIKGTRPRGGTTAEDTALAAALLASE
KDRAENLMIVDLMRNDLGRVSRLGSVTVPALCALETFASVHHLVSEVRSVLAPGRGPVDLLRACFPGGSITGAPKVRAME
IIHELEPAPRGPYCGSVAWIGFDGAMDSSIVIRTLVRAGETLVAQAGGGIVADSDPAAEYEESLVKVAPLLKAAAGETP

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=448, Percent_Identity=41.0714285714286, Blast_Score=305, Evalue=5e-84,
Organism=Escherichia coli, GI1787518, Length=378, Percent_Identity=31.4814814814815, Blast_Score=145, Evalue=4e-36,
Organism=Escherichia coli, GI1786809, Length=224, Percent_Identity=28.5714285714286, Blast_Score=73, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6320935, Length=442, Percent_Identity=34.6153846153846, Blast_Score=239, Evalue=1e-63,
Organism=Saccharomyces cerevisiae, GI6324361, Length=405, Percent_Identity=27.6543209876543, Blast_Score=120, Evalue=4e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890
- InterPro:   IPR005802 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 50304; Mature: 50304

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRHAVESPQPGDAPPVHVVPIAYGDPVRLFRAFADDPMAALLHSAAQDGARGRYSYIAA
CCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEEEC
EPFRVIVADADGVRVDGASVAGDPFTVLGAQLAACPAPEGLAPVPFAGGAVGFLGYELGR
CCEEEEEECCCCCEECCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHH
HVERLPPPKPGLPIPHMVMGLYDVVIAFDHAARAAVLISTGLPEIAANVRAARAKARVAH
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCEEEEEECCCHHHHHHHHHHHHHHHHHH
LLARLSKAPAEDTPPDITARADWTAELSRAEMEARIGRTVDYIHAGDIFQANITQRFLSR
HHHHHHHCCCCCCCCCCEECCCHHHHHHHHHHHHHHCCCEEEEECCCEEEHHHHHHHHHC
RPEGLSDYDLYRRLTALSPAPFSALLVCGPDLALMSASPERFLKVAPDGGVETRPIKGTR
CCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCEEECCCHHHHEEECCCCCCCCCCCCCCC
PRGGTTAEDTALAAALLASEKDRAENLMIVDLMRNDLGRVSRLGSVTVPALCALETFASV
CCCCCCHHHHHHHHHHHHCCHHHHCCEEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
HHLVSEVRSVLAPGRGPVDLLRACFPGGSITGAPKVRAMEIIHELEPAPRGPYCGSVAWI
HHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEE
GFDGAMDSSIVIRTLVRAGETLVAQAGGGIVADSDPAAEYEESLVKVAPLLKAAAGETP
EECCCCCHHHHHHHHHHCCCEEEEECCCCEEECCCCHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLRHAVESPQPGDAPPVHVVPIAYGDPVRLFRAFADDPMAALLHSAAQDGARGRYSYIAA
CCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEEEC
EPFRVIVADADGVRVDGASVAGDPFTVLGAQLAACPAPEGLAPVPFAGGAVGFLGYELGR
CCEEEEEECCCCCEECCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHH
HVERLPPPKPGLPIPHMVMGLYDVVIAFDHAARAAVLISTGLPEIAANVRAARAKARVAH
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCEEEEEECCCHHHHHHHHHHHHHHHHHH
LLARLSKAPAEDTPPDITARADWTAELSRAEMEARIGRTVDYIHAGDIFQANITQRFLSR
HHHHHHHCCCCCCCCCCEECCCHHHHHHHHHHHHHHCCCEEEEECCCEEEHHHHHHHHHC
RPEGLSDYDLYRRLTALSPAPFSALLVCGPDLALMSASPERFLKVAPDGGVETRPIKGTR
CCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCEEECCCHHHHEEECCCCCCCCCCCCCCC
PRGGTTAEDTALAAALLASEKDRAENLMIVDLMRNDLGRVSRLGSVTVPALCALETFASV
CCCCCCHHHHHHHHHHHHCCHHHHCCEEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
HHLVSEVRSVLAPGRGPVDLLRACFPGGSITGAPKVRAMEIIHELEPAPRGPYCGSVAWI
HHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEE
GFDGAMDSSIVIRTLVRAGETLVAQAGGGIVADSDPAAEYEESLVKVAPLLKAAAGETP
EECCCCCHHHHHHHHHHCCCEEEEECCCCEEECCCCHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3057324; 2251281 [H]