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The map label for this gene is ilvE [H]

Identifier: 158423221

GI number: 158423221

Start: 1822721

End: 1823506

Strand: Reverse

Name: ilvE [H]

Synonym: AZC_1597

Alternate gene names: 158423221

Gene position: 1823506-1822721 (Counterclockwise)

Preceding gene: 158423222

Following gene: 158423220

Centisome position: 33.96

GC content: 70.99

Gene sequence:

>786_bases
ATGAAGCTGTGGCTGAACGGCGGTCTCGTTGATGCCGCCGCCGCCCGCATCGCCCCCGGCGATCGCGGCTTCACGCTGGG
CGACGGCCTGTTCGAAACCATCGCCGTGCGCGGTGGCACGCCCCTGCGGTTGTCCGCCCACCTCGCCCGGCTCGCGCGGG
GCGCGGAGGTGATCGGCCTGCCGCTGCCGACCTTTGATCTGTCCGCCATAGCAACCGCACTGCTTGCCGCCAACGGCCTC
ACCGATGCGGTGCTGCGCCTCACCCTCACGCGCGGCGAAGGACCGCGCGGCGTACTGCCGCCTGAGGCGCCGCGACCGAC
GCTCCTCGTCACGGCTGCGCCAATGGCCGCCCCCGCGCCGCCGGCCCGTCTGATGCTGGCGCAGGGCACGCGGCGCAACG
AGTTCTCGCCGCTGAGCGGCATCAAGTCGCTGAACTATCTCGATAACATCCTCGCCCGGCAGGAAGCGCAGCGCGCCGGC
TGCGATGATGCGCTCCTCCTGAACACGCTAGGGCGCCTCGCCGAGAGCACCATCGCCAATCTCTTCGTGCAACGCGACGG
CCAGCTTCTCACCCCGCCCCTGTCGGAAGGCGCCCTGCCCGGCGTGATGCGGGCGGAGGTGCTGGCGCGCGGCGCCGTGG
AACGGCCGCTGACGTCGGACGATGTCGCGACCGCCGAAGAGGCTTTCCTCACCTCCAGCCTAGGCCTGCGATCTGTCCGG
TCCTTCGGCGACCGGGTGTTTTCGAGCTTCGCCGTGGCGGAGCGCCTGCGGACGGAGATCCCATGA

Upstream 100 bases:

>100_bases
CGGGCGGCGGCATCGTCGCCGACAGCGACCCAGCGGCGGAATATGAGGAGAGCCTGGTGAAAGTGGCGCCCCTGCTGAAG
GCGGCTGCGGGAGAGACGCC

Downstream 100 bases:

>100_bases
CCACGCCCGCCGGCTTTCCCATGCTGGACCTGCCCTATTCCACTCCGCCGGAAGCCCTCGTCGGCCCTCGCGTGCGCCTG
CGGCTGTGGCGCAAGGCGGA

Product: 4-amino-4-deoxychorismate lyase

Products: NA

Alternate protein names: BCAT; Transaminase B [H]

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MKLWLNGGLVDAAAARIAPGDRGFTLGDGLFETIAVRGGTPLRLSAHLARLARGAEVIGLPLPTFDLSAIATALLAANGL
TDAVLRLTLTRGEGPRGVLPPEAPRPTLLVTAAPMAAPAPPARLMLAQGTRRNEFSPLSGIKSLNYLDNILARQEAQRAG
CDDALLLNTLGRLAESTIANLFVQRDGQLLTPPLSEGALPGVMRAEVLARGAVERPLTSDDVATAEEAFLTSSLGLRSVR
SFGDRVFSSFAVAERLRTEIP

Sequences:

>Translated_261_residues
MKLWLNGGLVDAAAARIAPGDRGFTLGDGLFETIAVRGGTPLRLSAHLARLARGAEVIGLPLPTFDLSAIATALLAANGL
TDAVLRLTLTRGEGPRGVLPPEAPRPTLLVTAAPMAAPAPPARLMLAQGTRRNEFSPLSGIKSLNYLDNILARQEAQRAG
CDDALLLNTLGRLAESTIANLFVQRDGQLLTPPLSEGALPGVMRAEVLARGAVERPLTSDDVATAEEAFLTSSLGLRSVR
SFGDRVFSSFAVAERLRTEIP
>Mature_261_residues
MKLWLNGGLVDAAAARIAPGDRGFTLGDGLFETIAVRGGTPLRLSAHLARLARGAEVIGLPLPTFDLSAIATALLAANGL
TDAVLRLTLTRGEGPRGVLPPEAPRPTLLVTAAPMAAPAPPARLMLAQGTRRNEFSPLSGIKSLNYLDNILARQEAQRAG
CDDALLLNTLGRLAESTIANLFVQRDGQLLTPPLSEGALPGVMRAEVLARGAVERPLTSDDVATAEEAFLTSSLGLRSVR
SFGDRVFSSFAVAERLRTEIP

Specific function: Acts on leucine, isoleucine and valine [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI48994963, Length=250, Percent_Identity=26.4, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI1787338, Length=260, Percent_Identity=29.6153846153846, Blast_Score=82, Evalue=2e-17,

Paralogues:

None

Copy number: 2342 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 11,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001544
- InterPro:   IPR018300
- InterPro:   IPR005785 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =2.6.1.42 [H]

Molecular weight: Translated: 27431; Mature: 27431

Theoretical pI: Translated: 8.53; Mature: 8.53

Prosite motif: PS00770 AA_TRANSFER_CLASS_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLWLNGGLVDAAAARIAPGDRGFTLGDGLFETIAVRGGTPLRLSAHLARLARGAEVIGL
CEEEECCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEEEC
PLPTFDLSAIATALLAANGLTDAVLRLTLTRGEGPRGVLPPEAPRPTLLVTAAPMAAPAP
CCCCCCHHHHHHHHHHHCCHHHHHHEEEEECCCCCCCCCCCCCCCCEEEEEECCCCCCCC
PARLMLAQGTRRNEFSPLSGIKSLNYLDNILARQEAQRAGCDDALLLNTLGRLAESTIAN
CHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
LFVQRDGQLLTPPLSEGALPGVMRAEVLARGAVERPLTSDDVATAEEAFLTSSLGLRSVR
HHHHCCCCEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
SFGDRVFSSFAVAERLRTEIP
HHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKLWLNGGLVDAAAARIAPGDRGFTLGDGLFETIAVRGGTPLRLSAHLARLARGAEVIGL
CEEEECCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEEEC
PLPTFDLSAIATALLAANGLTDAVLRLTLTRGEGPRGVLPPEAPRPTLLVTAAPMAAPAP
CCCCCCHHHHHHHHHHHCCHHHHHHEEEEECCCCCCCCCCCCCCCCEEEEEECCCCCCCC
PARLMLAQGTRRNEFSPLSGIKSLNYLDNILARQEAQRAGCDDALLLNTLGRLAESTIAN
CHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
LFVQRDGQLLTPPLSEGALPGVMRAEVLARGAVERPLTSDDVATAEEAFLTSSLGLRSVR
HHHHCCCCEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
SFGDRVFSSFAVAERLRTEIP
HHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]