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The map label for this gene is arsC [H]

Identifier: 158422895

GI number: 158422895

Start: 1423442

End: 1423870

Strand: Direct

Name: arsC [H]

Synonym: AZC_1271

Alternate gene names: 158422895

Gene position: 1423442-1423870 (Clockwise)

Preceding gene: 158422894

Following gene: 158422896

Centisome position: 26.51

GC content: 63.87

Gene sequence:

>429_bases
ATGATGGACGTGGTCATCTACCACAACCCGGAATGTGGAACCTCCCGCAACACGTTGGCCCAGATCCTGAACGCTGGTGT
GGAGCCGCACGTCATCGAATACCTGAAGTGCCCACCTTCTCGCGTCATGCTTCGTCAGCTTGTCGACCGGGCCGGAATGA
CAGTCCGCGCCCTCCTGCGCGAAAAGGGCACGCCCTTCGCGGCGCTAGGTCTCGCCAATCCGGCGCTGACCGATGACGAC
CTGCTCGATGCCATGATGGCGCACCCAATCCTCATCAACCGTCCCCTGGTGGTGAGCCCGAAGGGTGTCCGGCTGTGCCG
CCCATCCGAAGAGGTCCTCGACCTCCTGCCGCCGCAGCGCGGCGCCTTCACCAAGGAAGACGGCGAACGCGTCGTCGACG
ACGCGGGAAACCGCGTGACCAATTCCTGA

Upstream 100 bases:

>100_bases
GCTCTCTCGATCGCATGGCGCTCCACAACCAGCTCCGCGCGATCGGTCAACTGACGGACGCTTATGTTGCCCGCTCAAAT
CTCCTCCATTCGGAGTCGAA

Downstream 100 bases:

>100_bases
GCTCTTTCCCTGGATTTGCGCCCATGCTCGCCGTCGCGATCTTCATCGCCACCCTCGTGCTCGTCATCTGGCAGCCGAGA
GGGCTAGGCATCGGCTGGAG

Product: arsenate reductase

Products: NA

Alternate protein names: Arsenical pump modifier [H]

Number of amino acids: Translated: 142; Mature: 142

Protein sequence:

>142_residues
MMDVVIYHNPECGTSRNTLAQILNAGVEPHVIEYLKCPPSRVMLRQLVDRAGMTVRALLREKGTPFAALGLANPALTDDD
LLDAMMAHPILINRPLVVSPKGVRLCRPSEEVLDLLPPQRGAFTKEDGERVVDDAGNRVTNS

Sequences:

>Translated_142_residues
MMDVVIYHNPECGTSRNTLAQILNAGVEPHVIEYLKCPPSRVMLRQLVDRAGMTVRALLREKGTPFAALGLANPALTDDD
LLDAMMAHPILINRPLVVSPKGVRLCRPSEEVLDLLPPQRGAFTKEDGERVVDDAGNRVTNS
>Mature_142_residues
MMDVVIYHNPECGTSRNTLAQILNAGVEPHVIEYLKCPPSRVMLRQLVDRAGMTVRALLREKGTPFAALGLANPALTDDD
LLDAMMAHPILINRPLVVSPKGVRLCRPSEEVLDLLPPQRGAFTKEDGERVVDDAGNRVTNS

Specific function: Reduction of arsenate [As(V)] to arsenite [As(III)]. This protein expands the substrate specificity of ArsAB pump which can extrude arsenite and antimonite to allow for arsenate pumping and resistance [H]

COG id: COG1393

COG function: function code P; Arsenate reductase and related proteins, glutaredoxin family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArsC family [H]

Homologues:

Organism=Escherichia coli, GI1789918, Length=140, Percent_Identity=59.2857142857143, Blast_Score=173, Evalue=3e-45,
Organism=Escherichia coli, GI1788841, Length=115, Percent_Identity=40.8695652173913, Blast_Score=90, Evalue=5e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006659
- InterPro:   IPR006660
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF03960 ArsC [H]

EC number: =1.20.4.1 [H]

Molecular weight: Translated: 15566; Mature: 15566

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMDVVIYHNPECGTSRNTLAQILNAGVEPHVIEYLKCPPSRVMLRQLVDRAGMTVRALLR
CCEEEEEECCCCCCCHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHH
EKGTPFAALGLANPALTDDDLLDAMMAHPILINRPLVVSPKGVRLCRPSEEVLDLLPPQR
HCCCCEEEEECCCCCCCCHHHHHHHHHCCEECCCCEEECCCCCEEECCHHHHHHHCCCCC
GAFTKEDGERVVDDAGNRVTNS
CCCCCCCCHHHHHCCCCCCCCC
>Mature Secondary Structure
MMDVVIYHNPECGTSRNTLAQILNAGVEPHVIEYLKCPPSRVMLRQLVDRAGMTVRALLR
CCEEEEEECCCCCCCHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHH
EKGTPFAALGLANPALTDDDLLDAMMAHPILINRPLVVSPKGVRLCRPSEEVLDLLPPQR
HCCCCEEEEECCCCCCCCHHHHHHHHHCCEECCCCEEECCCCCEEECCHHHHHHHCCCCC
GAFTKEDGERVVDDAGNRVTNS
CCCCCCCCHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3021763; 1703401; 1704144 [H]