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The map label for this gene is arsC [H]

Identifier: 158422894

GI number: 158422894

Start: 1422903

End: 1423445

Strand: Direct

Name: arsC [H]

Synonym: AZC_1270

Alternate gene names: 158422894

Gene position: 1422903-1423445 (Clockwise)

Preceding gene: 158422893

Following gene: 158422895

Centisome position: 26.5

GC content: 63.17

Gene sequence:

>543_bases
ATGACTGACCACACCTACAACGTGCTCTTCCTCTGCACGGGGAATTCGGCCCGCTCGATCCTCGGCGAGGCCATGCTGAA
CAAGCTTGGTGAAGGCCGCTTCCGCGCCTTCTCGGCGGGGAGCAAGCCCAAGGGCGAGGTCAACCCGCTTGCCATCGAGG
TGCTGCGGGAGGCGGACTTCCCGACCGACGGACTGTCTTCCAAGAGCTGGGAGGTGTTCGCCCGGGCGGATACTCCCACC
ATGGATTTCATCTTCACGGTCTGCGACGACGCGGCGGGCGAGACCTGCCCCATCTGGCCCGGCCACCCGGCGACGGCCCA
CTGGGGCATTGAAGATCCGGCAGCGGTCGAGGGAACCTATCTTGAGCGGCGGAAGGCTTTTGTCAGGGCGCAGCGCTATC
TCTTGAACCGGATTTCGGCATTCATGGCGCTTCCGCTGCGCTCTCTCGATCGCATGGCGCTCCACAACCAGCTCCGCGCG
ATCGGTCAACTGACGGACGCTTATGTTGCCCGCTCAAATCTCCTCCATTCGGAGTCGAAATGA

Upstream 100 bases:

>100_bases
GCAGCCTTCCTGATGCGGGACTGTTGCCAAGGCCATCCGGAGGTTTGCGCGCCCGCAATGCAGGCGCTGACCGCCTGTTC
ATGCCCGGAGCAAGGGTCAC

Downstream 100 bases:

>100_bases
TGGACGTGGTCATCTACCACAACCCGGAATGTGGAACCTCCCGCAACACGTTGGCCCAGATCCTGAACGCTGGTGTGGAG
CCGCACGTCATCGAATACCT

Product: low molecular weight phosphotyrosine protein phosphatase

Products: NA

Alternate protein names: Arsenate reductase; Arsenical pump modifier; Low molecular weight protein-tyrosine-phosphatase [H]

Number of amino acids: Translated: 180; Mature: 179

Protein sequence:

>180_residues
MTDHTYNVLFLCTGNSARSILGEAMLNKLGEGRFRAFSAGSKPKGEVNPLAIEVLREADFPTDGLSSKSWEVFARADTPT
MDFIFTVCDDAAGETCPIWPGHPATAHWGIEDPAAVEGTYLERRKAFVRAQRYLLNRISAFMALPLRSLDRMALHNQLRA
IGQLTDAYVARSNLLHSESK

Sequences:

>Translated_180_residues
MTDHTYNVLFLCTGNSARSILGEAMLNKLGEGRFRAFSAGSKPKGEVNPLAIEVLREADFPTDGLSSKSWEVFARADTPT
MDFIFTVCDDAAGETCPIWPGHPATAHWGIEDPAAVEGTYLERRKAFVRAQRYLLNRISAFMALPLRSLDRMALHNQLRA
IGQLTDAYVARSNLLHSESK
>Mature_179_residues
TDHTYNVLFLCTGNSARSILGEAMLNKLGEGRFRAFSAGSKPKGEVNPLAIEVLREADFPTDGLSSKSWEVFARADTPTM
DFIFTVCDDAAGETCPIWPGHPATAHWGIEDPAAVEGTYLERRKAFVRAQRYLLNRISAFMALPLRSLDRMALHNQLRAI
GQLTDAYVARSNLLHSESK

Specific function: Reduces arsenate [As(V)] to arsenite [As(III)] and dephosphorylates tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Could switch between different functions in different circumstances [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase superfamily. ArsC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014064
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 19930; Mature: 19799

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDHTYNVLFLCTGNSARSILGEAMLNKLGEGRFRAFSAGSKPKGEVNPLAIEVLREADF
CCCCCEEEEEEEECCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHHCCC
PTDGLSSKSWEVFARADTPTMDFIFTVCDDAAGETCPIWPGHPATAHWGIEDPAAVEGTY
CCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEECCCCCCCCCCHHH
LERRKAFVRAQRYLLNRISAFMALPLRSLDRMALHNQLRAIGQLTDAYVARSNLLHSESK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TDHTYNVLFLCTGNSARSILGEAMLNKLGEGRFRAFSAGSKPKGEVNPLAIEVLREADF
CCCCEEEEEEEECCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHHCCC
PTDGLSSKSWEVFARADTPTMDFIFTVCDDAAGETCPIWPGHPATAHWGIEDPAAVEGTY
CCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEECCCCCCCCCCHHH
LERRKAFVRAQRYLLNRISAFMALPLRSLDRMALHNQLRAIGQLTDAYVARSNLLHSESK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]