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The map label for this gene is arsB [H]

Identifier: 158422896

GI number: 158422896

Start: 1423894

End: 1425189

Strand: Direct

Name: arsB [H]

Synonym: AZC_1272

Alternate gene names: 158422896

Gene position: 1423894-1425189 (Clockwise)

Preceding gene: 158422895

Following gene: 158422904

Centisome position: 26.52

GC content: 65.28

Gene sequence:

>1296_bases
ATGCTCGCCGTCGCGATCTTCATCGCCACCCTCGTGCTCGTCATCTGGCAGCCGAGAGGGCTAGGCATCGGCTGGAGTGC
GCTCGGTGGCGCGGCTCTGGCGCTGGCGACGGGCGTGATCGGCCTCGCTGATGTCCCGGTGGTCTGGGACATCGTCTGGG
ATGCGACCTTCACCTTCGTCGCGCTCATCATCATCTCGCTGCTGCTGGATGAGGCGGGGTTCTTCCAATGGGCGGCCCTC
CATGTCGCCCGGTGGGGGAAGGGCCGAGGTGCACTCCTGTTTCCCCTCGTGATCCTGCTGGGCGCGGCGATCGCGGCCGT
GTTTGCGAACGACGGCGCGGCCCTCCTGCTGACGCCCATCGTGCTCGCCATCCTGCTGAGACTGAACTTCCGGCCTGCCG
CTGCCATGGCCTTCATCGTCGCCTGCGGCTTCGTGGCGGACAGCACGAGCTTGCCGCTGGTCATCTCGAACCTGGTCAAC
ATCGTCAGCGCGAACTTCTTCGGCATCACGTTTGACCGCTATGCGGCGGTCATGGTGCCGGTGAACGTCGTCTCCCTTGC
GGCGACCCTGATCGTGCTCTGGCTCTTCTATCGGAAGGACATCCCGGCGACCTACGATGTCGGCGAGCTCGATGTTCCAG
CAAGTGCGATCCGGGACCGGGGCGTGTTCGTCGCCGCTTTCCCTATGCTGGCGATCCTCCTCGCCGCATACTTCGTGACC
GCGCCCTTCGGCATCCCGGTGGCGGCTGTGACGGGGGCCGGTGCTCTTGTGCTCATAGCGGTCGCCGGGCTGGGGAATGC
CATTTCCGTCCGAAAGGCCGTGGCCTCCGCACCGTGGCAGATCGTGCTGTTCAGCCTCGGCATGTATCTGGTGGTCTACG
GGCTGAAGAATGCGGGTCTGACCGATCACCTCGCAGGCCTACTCCAGTGGTTCGCCGGACAGGGAACGATGGCCGGCGCG
ATCGGGACCGGCTTCACGTCGGCCATTCTGTCCTCGGTCATGAACAACATGCCCAGCGTCCTGATCGGGGCCATTGCCGT
CCAGCAGGCTCCGGACGTCTCCCCGCTCATGCGGGAGGTCATGGTCTATGCGAACGTCATTGGCTGCGACCTCGGCCCTA
AGTTCACCCCGATCGGAAGCCTCGCCACGCTGCTCTGGCTGCACGTGCTGGGCAGCAAGGGGCAGAAGATCACATGGGGG
GCGTACATGAAGGTCGGGCTGGTGATCACGCCGCCGGTCCTGCTGGTCACGCTCATCGCGCTGGCACTGTGGCTGCCGGT
GCTTGGCGTTCAGTAG

Upstream 100 bases:

>100_bases
CGCAGCGCGGCGCCTTCACCAAGGAAGACGGCGAACGCGTCGTCGACGACGCGGGAAACCGCGTGACCAATTCCTGAGCT
CTTTCCCTGGATTTGCGCCC

Downstream 100 bases:

>100_bases
CTTGAACCGTCGCCAAGAGTTGCGTGAAACCCATTACGCGGATCCGTGGCTAACGGCAGCTTTCAGCGTGCTGGGTCGTG
CAGGTCCATGTCCATAGATG

Product: arsenical pump membrane protein

Products: ADP; phosphate; arsenite [Periplasm] [C]

Alternate protein names: Arsenic efflux pump protein [H]

Number of amino acids: Translated: 431; Mature: 431

Protein sequence:

>431_residues
MLAVAIFIATLVLVIWQPRGLGIGWSALGGAALALATGVIGLADVPVVWDIVWDATFTFVALIIISLLLDEAGFFQWAAL
HVARWGKGRGALLFPLVILLGAAIAAVFANDGAALLLTPIVLAILLRLNFRPAAAMAFIVACGFVADSTSLPLVISNLVN
IVSANFFGITFDRYAAVMVPVNVVSLAATLIVLWLFYRKDIPATYDVGELDVPASAIRDRGVFVAAFPMLAILLAAYFVT
APFGIPVAAVTGAGALVLIAVAGLGNAISVRKAVASAPWQIVLFSLGMYLVVYGLKNAGLTDHLAGLLQWFAGQGTMAGA
IGTGFTSAILSSVMNNMPSVLIGAIAVQQAPDVSPLMREVMVYANVIGCDLGPKFTPIGSLATLLWLHVLGSKGQKITWG
AYMKVGLVITPPVLLVTLIALALWLPVLGVQ

Sequences:

>Translated_431_residues
MLAVAIFIATLVLVIWQPRGLGIGWSALGGAALALATGVIGLADVPVVWDIVWDATFTFVALIIISLLLDEAGFFQWAAL
HVARWGKGRGALLFPLVILLGAAIAAVFANDGAALLLTPIVLAILLRLNFRPAAAMAFIVACGFVADSTSLPLVISNLVN
IVSANFFGITFDRYAAVMVPVNVVSLAATLIVLWLFYRKDIPATYDVGELDVPASAIRDRGVFVAAFPMLAILLAAYFVT
APFGIPVAAVTGAGALVLIAVAGLGNAISVRKAVASAPWQIVLFSLGMYLVVYGLKNAGLTDHLAGLLQWFAGQGTMAGA
IGTGFTSAILSSVMNNMPSVLIGAIAVQQAPDVSPLMREVMVYANVIGCDLGPKFTPIGSLATLLWLHVLGSKGQKITWG
AYMKVGLVITPPVLLVTLIALALWLPVLGVQ
>Mature_431_residues
MLAVAIFIATLVLVIWQPRGLGIGWSALGGAALALATGVIGLADVPVVWDIVWDATFTFVALIIISLLLDEAGFFQWAAL
HVARWGKGRGALLFPLVILLGAAIAAVFANDGAALLLTPIVLAILLRLNFRPAAAMAFIVACGFVADSTSLPLVISNLVN
IVSANFFGITFDRYAAVMVPVNVVSLAATLIVLWLFYRKDIPATYDVGELDVPASAIRDRGVFVAAFPMLAILLAAYFVT
APFGIPVAAVTGAGALVLIAVAGLGNAISVRKAVASAPWQIVLFSLGMYLVVYGLKNAGLTDHLAGLLQWFAGQGTMAGA
IGTGFTSAILSSVMNNMPSVLIGAIAVQQAPDVSPLMREVMVYANVIGCDLGPKFTPIGSLATLLWLHVLGSKGQKITWG
AYMKVGLVITPPVLLVTLIALALWLPVLGVQ

Specific function: Involved in arsenical resistance. Thought to form the channel of an arsenite pump [H]

COG id: COG1055

COG function: function code P; Na+/H+ antiporter NhaD and related arsenite permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArsB family [H]

Homologues:

Organism=Escherichia coli, GI87082277, Length=425, Percent_Identity=60.9411764705882, Blast_Score=499, Evalue=1e-142,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000802 [H]

Pfam domain/function: PF02040 ArsB [H]

EC number: NA

Molecular weight: Translated: 44996; Mature: 44996

Theoretical pI: Translated: 8.64; Mature: 8.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAVAIFIATLVLVIWQPRGLGIGWSALGGAALALATGVIGLADVPVVWDIVWDATFTFV
CHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
ALIIISLLLDEAGFFQWAALHVARWGKGRGALLFPLVILLGAAIAAVFANDGAALLLTPI
HHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
VLAILLRLNFRPAAAMAFIVACGFVADSTSLPLVISNLVNIVSANFFGITFDRYAAVMVP
HHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHEEEHHHHHHHHHH
VNVVSLAATLIVLWLFYRKDIPATYDVGELDVPASAIRDRGVFVAAFPMLAILLAAYFVT
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHH
APFGIPVAAVTGAGALVLIAVAGLGNAISVRKAVASAPWQIVLFSLGMYLVVYGLKNAGL
CCCCCCHHHHHCCCHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCH
TDHLAGLLQWFAGQGTMAGAIGTGFTSAILSSVMNNMPSVLIGAIAVQQAPDVSPLMREV
HHHHHHHHHHHCCCCCCCCHHHCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHH
MVYANVIGCDLGPKFTPIGSLATLLWLHVLGSKGQKITWGAYMKVGLVITPPVLLVTLIA
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEHHHHEECEEECCHHHHHHHHH
LALWLPVLGVQ
HHHHHHHHCCC
>Mature Secondary Structure
MLAVAIFIATLVLVIWQPRGLGIGWSALGGAALALATGVIGLADVPVVWDIVWDATFTFV
CHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
ALIIISLLLDEAGFFQWAALHVARWGKGRGALLFPLVILLGAAIAAVFANDGAALLLTPI
HHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
VLAILLRLNFRPAAAMAFIVACGFVADSTSLPLVISNLVNIVSANFFGITFDRYAAVMVP
HHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHEEEHHHHHHHHHH
VNVVSLAATLIVLWLFYRKDIPATYDVGELDVPASAIRDRGVFVAAFPMLAILLAAYFVT
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHH
APFGIPVAAVTGAGALVLIAVAGLGNAISVRKAVASAPWQIVLFSLGMYLVVYGLKNAGL
CCCCCCHHHHHCCCHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCH
TDHLAGLLQWFAGQGTMAGAIGTGFTSAILSSVMNNMPSVLIGAIAVQQAPDVSPLMREV
HHHHHHHHHHHCCCCCCCCHHHCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHH
MVYANVIGCDLGPKFTPIGSLATLLWLHVLGSKGQKITWGAYMKVGLVITPPVLLVTLIA
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEHHHHEECEEECCHHHHHHHHH
LALWLPVLGVQ
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; arsenite [Cytoplasm]; H2O [C]

Specific reaction: ATP + arsenite [Cytoplasm] + H2O = ADP + phosphate + arsenite [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9006011 [H]