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The map label for this gene is dapA [H]

Identifier: 158422867

GI number: 158422867

Start: 1394043

End: 1394942

Strand: Direct

Name: dapA [H]

Synonym: AZC_1243

Alternate gene names: 158422867

Gene position: 1394043-1394942 (Clockwise)

Preceding gene: 158422863

Following gene: 158422868

Centisome position: 25.96

GC content: 66.44

Gene sequence:

>900_bases
ATGTCTTCCGCTTCGCCCAACGCTCTGTTCCGTGGCTCCTTTACCGCGCTCGTGACGCCGTTCCGCGATGGGGCCCTGGA
CGAGAAAGCGTTCCGCGATCTCGTGGAGTGGCAGATCGCCGAGGGTACCAATGGGCTCGTGCCGGTGGGCACCACGGGCG
AGAGCCCGACGCTCAGCCACGACGAGCACAAGCGCGTGATCGAGTGGGCGGTGTCGCAGGCCGCCGGCCGCGTGCCGGTG
ATGGCCGGCGCGGGCTCCAACGATACGGCGACCGCCATCGAGTTTTCCCAGCATGCCGAGAAGGTCGGCGCGCAGGGCCT
GCTCGTGGTTACGCCCTATTACAACAAGCCCTCGCAGGAGGGCCTGTACCAGCACTTCGCGGCCATCGCGAAGGCGGTGA
GCCTGCCCATCTTCATCTACAACATCCCCGCCCGCTCGGTGATCGACATGAGCGTCGAGACCATGGCGCGTCTGCGCGAG
TTCCCCAACATTGTCGGCATCAAGGACGCCACCGCCAACATGTCGCGCGTGTCCCTGCAGCGCCAGACGCTGGGCAAGGA
CTTCATCCAGCTCTCGGGCGAGGACATTACCGCGCTGGGCTTCAACGCCCATGGCGGGGTGGGCTGCATCTCGGTGACGG
CGAACGTTGCCCCGCGCCTGTGCGCGGAGTTCCAGGCCGCCTGCACCAGGGGCGATTATGCCGCCGCGCTCGCCATCCAG
GACAAGCTGGTGCCGCTGCACACGGCGCTCTTCGTTGAAACCAACCCGTCGCCCACCAAATATGCCCTGTCCGTTCTGGG
CAAGATGGCCGAGGACGTGCGCCTGCCCATGGTGCCGGTCTCGGAGCCGACCAAGGCCGTGGTGAAGAGCGCCATGGTCC
ATGCCGGCCTCATCAACTGA

Upstream 100 bases:

>100_bases
GGGGCCTTTCGCTGACGCGGACAACGCTGTATCTGTCGCGGTCCGCTTTGCCCCGCGCCAAGGGGGCGGGTGCGTTCATA
ACCCAGAACAAGGCCCTGCC

Downstream 100 bases:

>100_bases
TCCTGCGCCGGGCCGGATGGCGACATCCGGCCGCGTCCGCGCTGCCGAGGGCGGGGCGCCACCCGTGCCCCGTCCCGTTT
CGAGAGTGTGATGGCTGAGA

Product: dihydrodipicolinate synthase subfamily protein

Products: NA

Alternate protein names: DHDPS [H]

Number of amino acids: Translated: 299; Mature: 298

Protein sequence:

>299_residues
MSSASPNALFRGSFTALVTPFRDGALDEKAFRDLVEWQIAEGTNGLVPVGTTGESPTLSHDEHKRVIEWAVSQAAGRVPV
MAGAGSNDTATAIEFSQHAEKVGAQGLLVVTPYYNKPSQEGLYQHFAAIAKAVSLPIFIYNIPARSVIDMSVETMARLRE
FPNIVGIKDATANMSRVSLQRQTLGKDFIQLSGEDITALGFNAHGGVGCISVTANVAPRLCAEFQAACTRGDYAAALAIQ
DKLVPLHTALFVETNPSPTKYALSVLGKMAEDVRLPMVPVSEPTKAVVKSAMVHAGLIN

Sequences:

>Translated_299_residues
MSSASPNALFRGSFTALVTPFRDGALDEKAFRDLVEWQIAEGTNGLVPVGTTGESPTLSHDEHKRVIEWAVSQAAGRVPV
MAGAGSNDTATAIEFSQHAEKVGAQGLLVVTPYYNKPSQEGLYQHFAAIAKAVSLPIFIYNIPARSVIDMSVETMARLRE
FPNIVGIKDATANMSRVSLQRQTLGKDFIQLSGEDITALGFNAHGGVGCISVTANVAPRLCAEFQAACTRGDYAAALAIQ
DKLVPLHTALFVETNPSPTKYALSVLGKMAEDVRLPMVPVSEPTKAVVKSAMVHAGLIN
>Mature_298_residues
SSASPNALFRGSFTALVTPFRDGALDEKAFRDLVEWQIAEGTNGLVPVGTTGESPTLSHDEHKRVIEWAVSQAAGRVPVM
AGAGSNDTATAIEFSQHAEKVGAQGLLVVTPYYNKPSQEGLYQHFAAIAKAVSLPIFIYNIPARSVIDMSVETMARLREF
PNIVGIKDATANMSRVSLQRQTLGKDFIQLSGEDITALGFNAHGGVGCISVTANVAPRLCAEFQAACTRGDYAAALAIQD
KLVPLHTALFVETNPSPTKYALSVLGKMAEDVRLPMVPVSEPTKAVVKSAMVHAGLIN

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; first step. [C]

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI31543060, Length=276, Percent_Identity=27.1739130434783, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI13540533, Length=248, Percent_Identity=26.2096774193548, Blast_Score=75, Evalue=8e-14,
Organism=Escherichia coli, GI1788823, Length=292, Percent_Identity=47.2602739726027, Blast_Score=276, Evalue=1e-75,
Organism=Escherichia coli, GI87082415, Length=296, Percent_Identity=33.1081081081081, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1786463, Length=289, Percent_Identity=32.5259515570934, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1789620, Length=234, Percent_Identity=30.7692307692308, Blast_Score=99, Evalue=4e-22,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625
- InterPro:   IPR020624 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 31823; Mature: 31692

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS00665 DHDPS_1 ; PS00666 DHDPS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSASPNALFRGSFTALVTPFRDGALDEKAFRDLVEWQIAEGTNGLVPVGTTGESPTLSH
CCCCCCCEEECCCCEEEEECCCCCCCCHHHHHHHHHEEECCCCCCEEEECCCCCCCCCCC
DEHKRVIEWAVSQAAGRVPVMAGAGSNDTATAIEFSQHAEKVGAQGLLVVTPYYNKPSQE
HHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCHH
GLYQHFAAIAKAVSLPIFIYNIPARSVIDMSVETMARLREFPNIVGIKDATANMSRVSLQ
HHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHHCCCCEECCCCCCCHHHHHHH
RQTLGKDFIQLSGEDITALGFNAHGGVGCISVTANVAPRLCAEFQAACTRGDYAAALAIQ
HHHHCCHHHHCCCCCEEEEECCCCCCEEEEEEEHHHHHHHHHHHHHHHCCCCCEEEEEEC
DKLVPLHTALFVETNPSPTKYALSVLGKMAEDVRLPMVPVSEPTKAVVKSAMVHAGLIN
CCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SSASPNALFRGSFTALVTPFRDGALDEKAFRDLVEWQIAEGTNGLVPVGTTGESPTLSH
CCCCCCEEECCCCEEEEECCCCCCCCHHHHHHHHHEEECCCCCCEEEECCCCCCCCCCC
DEHKRVIEWAVSQAAGRVPVMAGAGSNDTATAIEFSQHAEKVGAQGLLVVTPYYNKPSQE
HHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCHH
GLYQHFAAIAKAVSLPIFIYNIPARSVIDMSVETMARLREFPNIVGIKDATANMSRVSLQ
HHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHHCCCCEECCCCCCCHHHHHHH
RQTLGKDFIQLSGEDITALGFNAHGGVGCISVTANVAPRLCAEFQAACTRGDYAAALAIQ
HHHHCCHHHHCCCCCEEEEECCCCCCEEEEEEEHHHHHHHHHHHHHHHCCCCCEEEEEEC
DKLVPLHTALFVETNPSPTKYALSVLGKMAEDVRLPMVPVSEPTKAVVKSAMVHAGLIN
CCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]