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The map label for this gene is fdoG [H]

Identifier: 158422784

GI number: 158422784

Start: 1294594

End: 1295268

Strand: Reverse

Name: fdoG [H]

Synonym: AZC_1160

Alternate gene names: 158422784

Gene position: 1295268-1294594 (Counterclockwise)

Preceding gene: 158422789

Following gene: 158422783

Centisome position: 24.12

GC content: 63.41

Gene sequence:

>675_bases
ATGCAGGTTGGCGACCGGTTCTCCAACCCATTCCCGGTCCCCCGTGTGGGGCAATCGTGTCGGAGGCACACTTCGATGAA
TATGGAGCTCTCGCGGCGCCAGTTCCTAGGAACGGCCGGCGCGGGTCTCGCGGGTACGACGCTCGGAGCGCTTGGCTTCG
GGCCGGCTGAAGAGGCGCAGGCAGCTGCGATTCGCCCCTTCAAGCTTTTCAACACCACCGAGACCAGAAACACCTGCACC
TACTGTTCCGTGGCGTGCGGTATCCTCATCTTCTCCAAGGGCGACCTGAAGAAGGGCGAGAAGGCGGACATCACCCACAT
CGAGGGTGACGTCGACCATCCGACCAACCGCGGCACGCTCTGCCCGAAGGGCGCCGCCCTTCTGGACATCGTGAAGTCCG
AGACCCGTCTCAAGCAGCCGATGATCCGGCGCGCGGGCTCGAACAAGTTCGAAGCCATCTCCTGGGATGCGGCGCTCGAC
AAGATCGCCCGCGCCATGAAGGACGATCGCGACGCGAACTTCATCGCGAAGAATGCCGACGGCGTGACGGTCAACCGCTG
GACCACGACCGGCTTCCTCGCAGCTTCTGCAACGACGAACGAGACCGCCTGGGCGACCTACAAGGTCGTTCGCAGTCTCG
GCATGGTGGTTTTCGACAATCAGGCGCGCGTCTGA

Upstream 100 bases:

>100_bases
TCGCAGCGTCCAAGAAAGCGCAGCGGATGCCCATACCAAAGTATGCTCATCTGTAGTTTGACATCGTTCCAGTTACAAAA
TAGCTTGCCAGCAAGCCGGA

Downstream 100 bases:

>100_bases
CACGGCCCCACGGTGTCCAGTTTGGGCCCAACTTTTGGCCGTGGCGCGATGACCAATTCGTGGACCGATATTCGGAACAC
GGATCTTGTCGTGATCATGG

Product: twin-arginine translocation pathway signal precursor

Products: NA

Alternate protein names: Aerobic formate dehydrogenase major subunit; FDH-Z subunit alpha; Formate dehydrogenase-O subunit alpha [H]

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MQVGDRFSNPFPVPRVGQSCRRHTSMNMELSRRQFLGTAGAGLAGTTLGALGFGPAEEAQAAAIRPFKLFNTTETRNTCT
YCSVACGILIFSKGDLKKGEKADITHIEGDVDHPTNRGTLCPKGAALLDIVKSETRLKQPMIRRAGSNKFEAISWDAALD
KIARAMKDDRDANFIAKNADGVTVNRWTTTGFLAASATTNETAWATYKVVRSLGMVVFDNQARV

Sequences:

>Translated_224_residues
MQVGDRFSNPFPVPRVGQSCRRHTSMNMELSRRQFLGTAGAGLAGTTLGALGFGPAEEAQAAAIRPFKLFNTTETRNTCT
YCSVACGILIFSKGDLKKGEKADITHIEGDVDHPTNRGTLCPKGAALLDIVKSETRLKQPMIRRAGSNKFEAISWDAALD
KIARAMKDDRDANFIAKNADGVTVNRWTTTGFLAASATTNETAWATYKVVRSLGMVVFDNQARV
>Mature_224_residues
MQVGDRFSNPFPVPRVGQSCRRHTSMNMELSRRQFLGTAGAGLAGTTLGALGFGPAEEAQAAAIRPFKLFNTTETRNTCT
YCSVACGILIFSKGDLKKGEKADITHIEGDVDHPTNRGTLCPKGAALLDIVKSETRLKQPMIRRAGSNKFEAISWDAALD
KIARAMKDDRDANFIAKNADGVTVNRWTTTGFLAASATTNETAWATYKVVRSLGMVVFDNQARV

Specific function: Allows to use formate as major electron donor during aerobic respiration. Subunit alpha possibly forms the active site [H]

COG id: COG0243

COG function: function code C; Anaerobic dehydrogenases, typically selenocysteine-containing

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI3868720, Length=197, Percent_Identity=59.3908629441624, Blast_Score=246, Evalue=1e-66,
Organism=Escherichia coli, GI3868719, Length=197, Percent_Identity=57.8680203045685, Blast_Score=230, Evalue=5e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR006443
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006963
- InterPro:   IPR006655
- InterPro:   IPR006311 [H]

Pfam domain/function: PF04879 Molybdop_Fe4S4; PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: =1.2.1.2 [H]

Molecular weight: Translated: 24290; Mature: 24290

Theoretical pI: Translated: 9.89; Mature: 9.89

Prosite motif: PS00551 MOLYBDOPTERIN_PROK_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVGDRFSNPFPVPRVGQSCRRHTSMNMELSRRQFLGTAGAGLAGTTLGALGFGPAEEAQ
CCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHCCCCCCCHHHHHHHCCCCCCHHHH
AAAIRPFKLFNTTETRNTCTYCSVACGILIFSKGDLKKGEKADITHIEGDVDHPTNRGTL
HHHCCCEEEECCCCCCCCHHHHHHHHCEEEECCCCCCCCCCCCCEEECCCCCCCCCCCCC
CPKGAALLDIVKSETRLKQPMIRRAGSNKFEAISWDAALDKIARAMKDDRDANFIAKNAD
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHCCCCCCEEEECCC
GVTVNRWTTTGFLAASATTNETAWATYKVVRSLGMVVFDNQARV
CEEEEEEECCEEEEECCCCCCHHHHHHHHHHHCCCEEECCCCCC
>Mature Secondary Structure
MQVGDRFSNPFPVPRVGQSCRRHTSMNMELSRRQFLGTAGAGLAGTTLGALGFGPAEEAQ
CCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHCCCCCCCHHHHHHHCCCCCCHHHH
AAAIRPFKLFNTTETRNTCTYCSVACGILIFSKGDLKKGEKADITHIEGDVDHPTNRGTL
HHHCCCEEEECCCCCCCCHHHHHHHHCEEEECCCCCCCCCCCCCEEECCCCCCCCCCCCC
CPKGAALLDIVKSETRLKQPMIRRAGSNKFEAISWDAALDKIARAMKDDRDANFIAKNAD
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHCCCCCCEEEECCC
GVTVNRWTTTGFLAASATTNETAWATYKVVRSLGMVVFDNQARV
CEEEEEEECCEEEEECCCCCCHHHHHHHHHHHCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8346018; 9278503; 8522521 [H]