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The map label for this gene is fdoG [H]

Identifier: 158422783

GI number: 158422783

Start: 1292107

End: 1294581

Strand: Reverse

Name: fdoG [H]

Synonym: AZC_1159

Alternate gene names: 158422783

Gene position: 1294581-1292107 (Counterclockwise)

Preceding gene: 158422784

Following gene: 158422782

Centisome position: 24.11

GC content: 63.31

Gene sequence:

>2475_bases
GTGTCCAGTTTGGGCCCAACTTTTGGCCGTGGCGCGATGACCAATTCGTGGACCGATATTCGGAACACGGATCTTGTCGT
GATCATGGGCGGCAATGCCGCCGAAGCACATCCTTGCGGTTTCAAGTGGGTCGTGGAGGCGAAGGCCAACCGCGGCGCGA
AGCTTGTCGTCGTTGATCCGCGCTTCACGCGGTCCGCGGCGGTCGCCGACTATTACGCCCCCATCCGTCAGGGCTCCGAC
ATCGCCTTCCTGCTCGGCGTGATCAATTACTGCATCCAGAACAACAAGGTGCAGTGGGATTACGTCAAAGCCTTCACCAA
CGCGACGTACCTCGTGAAGGACGGCTTCGAGTATCGGGACGGCCTGTTCACGGGCTATGACGAGGAGAAGCGCGACTACA
ACCGCTCCACCTGGGATTACCAGATCGGCCCCGATGGCTATGCCATGGTGGACGAGACGCTGGAGAATCCGCGCTGCGTC
TGGAACCTGCTCAAGGCCCACGTCGCCCAGTACACGCCCGAAATGGTCGAGCGCATCAGCGGCACGCCGAAGGACAAGTT
CCTGAAGGTCGCCGCCATGATCGCGGAGTGCTCATCGCCCACCAAGACGATGACCTCCATGTACGCGCTCGGCTGGACCC
AGCACTCCAAGGGCTCGCAGAACATCCGCTGCATGGCGATGCTCCAGCTCATCCTGGGCAACATCGGCGTGCGCGGCGGC
GGCATGAACGCCCTGCGTGGTCACTCCAACATCCAGGGCCTCACCGACATCGGCCTGATGTCGAACATGATCCCCGGCTA
CCTGAACCTGCCCACGGAACGGGAACCGGACTTCGCCACCTACATGTCGACCCGCGGCTTCAAGCCGTTGCGGCCGAACC
AGATGAGCTACTGGCAGAACTACAAGAAGTTCATGGTGAGCTTCCTGAAGTCCATGTGGGGCCCGGCGGCGACCGCGGAG
AACAACTTCGCGTTCGACTGGCTGCCCAAGCTGGATGTCCCGACCTACGACATCCTGCGCGCGTTCGAGCTCATGAAGCA
GGGGAAGATGAACCTCTACTTCTGCCAGGGCTTCAACCCGCTGCAGGCGTTCCCCAACCGGAACAAGCTGTCGGCGGCGC
TGTCCAGGCTGAAGATGCTGGTCATCATGGACCCGCTGGAAACGGAGACCGCCCGTTTCTGGGAAAACCACGGCGTCTAT
AACGACGTCGATCCCTCCAAGATCCAGACCGAGGTCATCCAGCTCCCCACCACCTGCTTTGCGGAGGATGAGGGCTCGCT
GGTGAACTCCGGCCGCTGGCTCCAGTGGCACTGGCCGGCCGGCTCGCCTCCGGGCGAGGCGCGCACCGACGCCTGGATCA
TGTCGCAGATCCATCTGCGGCTGAAGGAGATGTACCGGAAGGAAGGCGGGGCCCTGCCGGACCCCATCGTCAACCTCTCC
TGGACCTACAAGAACCCGGACGAGCCGACGCCCGAGGAGCTCACCAAGGAGCTCAACGGCTATGTGGTCTCCGACGTGCT
GGATCCGAACGATCCCACCAAGAAGCTGCTGACCGCCGGCAAGCAGGTGCCGAACTTCGGCGTGCTGCGCGACGACGGTT
CCACGGCTGCGGGCTGCTGGATCTACTCCGGCTCCTTCACCGAGGACGGCAACATGATGGCCCGTCGGGACAATTCCGAT
CCCGACAACACCGGAGCGTATCTGAAGTGGTCGTTCGCCTGGCCGGCGAACCGCCGCATCATCTACAACCGCGCCTCCGC
CGACATCAACGGCAAGCCGTGGGATGACACCCGCAAGCTGCTGTGGTGGGACGGGGCCAAGTGGACCGGCTACGACGTGC
CCGACATCGCCCCCACGGCGAAGCCGCAGGACGTCGGCCCCTTCATCATGAACCCGGAAGGCGTGTCCCGCCTGTTCGCC
CGGGGCATGATGCGCGACGGTCCCTTCCCGGTGCATTACGAGCCGTTCGAGAGCCCGCTGGTCAATGTGATCGCCCCCAA
GGTGCGGGGCAATCCGGTGGCGCGCGTGTTCAAGGACGACTTCGCCCAGTTCGCGGAGCCGGCGTCGAAGGAGTTCCCCT
ATGCGGCGACCTCCTATCGTCTCACGGAGCACTTCCACTACTGGACCAAGAACAACCATGTGAACTCGGTCCTGCAGCCG
GAATTCTTCGTGGAGATCTCGGAAGAGCTCGCGAAGGAGAAGTCCATCAACAATGGCGGCTGGGTGCGCGTGTGGTCCAA
GCGCGGCTCGGTGTTTGCCAAGGCCTATGTGACGAAGCGCATCCGTCCGCTCATCTGCGACGGCAAGCCGGTGCACGTGG
TCGGCATCCCGATCCACTGGGGCTTCGTGGGCGCGGCCAAGAAGGGCTTCCCCGCGAACGTGCTCACCCCGTTCGTCGGT
GACGCGAACATCGAGACGCCGGAGTTCAAGGCGTTTCTGGTCAATATCGAGCCCACGACCGGGCCGGTGGCGTGA

Upstream 100 bases:

>100_bases
TGCAACGACGAACGAGACCGCCTGGGCGACCTACAAGGTCGTTCGCAGTCTCGGCATGGTGGTTTTCGACAATCAGGCGC
GCGTCTGACACGGCCCCACG

Downstream 100 bases:

>100_bases
GGGAGGGTCGAACCATGTTGCAACCAGCACCGAACCCTCCGGTCGCCCCCACCCCGGCGAAGTTCTCGGACCAGGATCTG
CTGCGGAAGTCGGCGTCCAC

Product: formate dehydrogenase subunit alpha

Products: NA

Alternate protein names: Aerobic formate dehydrogenase major subunit; FDH-Z subunit alpha; Formate dehydrogenase-O subunit alpha [H]

Number of amino acids: Translated: 824; Mature: 823

Protein sequence:

>824_residues
MSSLGPTFGRGAMTNSWTDIRNTDLVVIMGGNAAEAHPCGFKWVVEAKANRGAKLVVVDPRFTRSAAVADYYAPIRQGSD
IAFLLGVINYCIQNNKVQWDYVKAFTNATYLVKDGFEYRDGLFTGYDEEKRDYNRSTWDYQIGPDGYAMVDETLENPRCV
WNLLKAHVAQYTPEMVERISGTPKDKFLKVAAMIAECSSPTKTMTSMYALGWTQHSKGSQNIRCMAMLQLILGNIGVRGG
GMNALRGHSNIQGLTDIGLMSNMIPGYLNLPTEREPDFATYMSTRGFKPLRPNQMSYWQNYKKFMVSFLKSMWGPAATAE
NNFAFDWLPKLDVPTYDILRAFELMKQGKMNLYFCQGFNPLQAFPNRNKLSAALSRLKMLVIMDPLETETARFWENHGVY
NDVDPSKIQTEVIQLPTTCFAEDEGSLVNSGRWLQWHWPAGSPPGEARTDAWIMSQIHLRLKEMYRKEGGALPDPIVNLS
WTYKNPDEPTPEELTKELNGYVVSDVLDPNDPTKKLLTAGKQVPNFGVLRDDGSTAAGCWIYSGSFTEDGNMMARRDNSD
PDNTGAYLKWSFAWPANRRIIYNRASADINGKPWDDTRKLLWWDGAKWTGYDVPDIAPTAKPQDVGPFIMNPEGVSRLFA
RGMMRDGPFPVHYEPFESPLVNVIAPKVRGNPVARVFKDDFAQFAEPASKEFPYAATSYRLTEHFHYWTKNNHVNSVLQP
EFFVEISEELAKEKSINNGGWVRVWSKRGSVFAKAYVTKRIRPLICDGKPVHVVGIPIHWGFVGAAKKGFPANVLTPFVG
DANIETPEFKAFLVNIEPTTGPVA

Sequences:

>Translated_824_residues
MSSLGPTFGRGAMTNSWTDIRNTDLVVIMGGNAAEAHPCGFKWVVEAKANRGAKLVVVDPRFTRSAAVADYYAPIRQGSD
IAFLLGVINYCIQNNKVQWDYVKAFTNATYLVKDGFEYRDGLFTGYDEEKRDYNRSTWDYQIGPDGYAMVDETLENPRCV
WNLLKAHVAQYTPEMVERISGTPKDKFLKVAAMIAECSSPTKTMTSMYALGWTQHSKGSQNIRCMAMLQLILGNIGVRGG
GMNALRGHSNIQGLTDIGLMSNMIPGYLNLPTEREPDFATYMSTRGFKPLRPNQMSYWQNYKKFMVSFLKSMWGPAATAE
NNFAFDWLPKLDVPTYDILRAFELMKQGKMNLYFCQGFNPLQAFPNRNKLSAALSRLKMLVIMDPLETETARFWENHGVY
NDVDPSKIQTEVIQLPTTCFAEDEGSLVNSGRWLQWHWPAGSPPGEARTDAWIMSQIHLRLKEMYRKEGGALPDPIVNLS
WTYKNPDEPTPEELTKELNGYVVSDVLDPNDPTKKLLTAGKQVPNFGVLRDDGSTAAGCWIYSGSFTEDGNMMARRDNSD
PDNTGAYLKWSFAWPANRRIIYNRASADINGKPWDDTRKLLWWDGAKWTGYDVPDIAPTAKPQDVGPFIMNPEGVSRLFA
RGMMRDGPFPVHYEPFESPLVNVIAPKVRGNPVARVFKDDFAQFAEPASKEFPYAATSYRLTEHFHYWTKNNHVNSVLQP
EFFVEISEELAKEKSINNGGWVRVWSKRGSVFAKAYVTKRIRPLICDGKPVHVVGIPIHWGFVGAAKKGFPANVLTPFVG
DANIETPEFKAFLVNIEPTTGPVA
>Mature_823_residues
SSLGPTFGRGAMTNSWTDIRNTDLVVIMGGNAAEAHPCGFKWVVEAKANRGAKLVVVDPRFTRSAAVADYYAPIRQGSDI
AFLLGVINYCIQNNKVQWDYVKAFTNATYLVKDGFEYRDGLFTGYDEEKRDYNRSTWDYQIGPDGYAMVDETLENPRCVW
NLLKAHVAQYTPEMVERISGTPKDKFLKVAAMIAECSSPTKTMTSMYALGWTQHSKGSQNIRCMAMLQLILGNIGVRGGG
MNALRGHSNIQGLTDIGLMSNMIPGYLNLPTEREPDFATYMSTRGFKPLRPNQMSYWQNYKKFMVSFLKSMWGPAATAEN
NFAFDWLPKLDVPTYDILRAFELMKQGKMNLYFCQGFNPLQAFPNRNKLSAALSRLKMLVIMDPLETETARFWENHGVYN
DVDPSKIQTEVIQLPTTCFAEDEGSLVNSGRWLQWHWPAGSPPGEARTDAWIMSQIHLRLKEMYRKEGGALPDPIVNLSW
TYKNPDEPTPEELTKELNGYVVSDVLDPNDPTKKLLTAGKQVPNFGVLRDDGSTAAGCWIYSGSFTEDGNMMARRDNSDP
DNTGAYLKWSFAWPANRRIIYNRASADINGKPWDDTRKLLWWDGAKWTGYDVPDIAPTAKPQDVGPFIMNPEGVSRLFAR
GMMRDGPFPVHYEPFESPLVNVIAPKVRGNPVARVFKDDFAQFAEPASKEFPYAATSYRLTEHFHYWTKNNHVNSVLQPE
FFVEISEELAKEKSINNGGWVRVWSKRGSVFAKAYVTKRIRPLICDGKPVHVVGIPIHWGFVGAAKKGFPANVLTPFVGD
ANIETPEFKAFLVNIEPTTGPVA

Specific function: Allows to use formate as major electron donor during aerobic respiration. Subunit alpha possibly forms the active site [H]

COG id: COG0243

COG function: function code C; Anaerobic dehydrogenases, typically selenocysteine-containing

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI3868720, Length=818, Percent_Identity=58.9242053789731, Blast_Score=1031, Evalue=0.0,
Organism=Escherichia coli, GI3868719, Length=818, Percent_Identity=57.7017114914425, Blast_Score=1016, Evalue=0.0,
Organism=Escherichia coli, GI3868721, Length=464, Percent_Identity=25.8620689655172, Blast_Score=132, Evalue=7e-32,
Organism=Escherichia coli, GI1788534, Length=460, Percent_Identity=24.7826086956522, Blast_Score=105, Evalue=2e-23,
Organism=Escherichia coli, GI87081797, Length=256, Percent_Identity=27.34375, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI171474008, Length=245, Percent_Identity=27.7551020408163, Blast_Score=80, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR006443
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006963
- InterPro:   IPR006655
- InterPro:   IPR006311 [H]

Pfam domain/function: PF04879 Molybdop_Fe4S4; PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: =1.2.1.2 [H]

Molecular weight: Translated: 92746; Mature: 92615

Theoretical pI: Translated: 7.76; Mature: 7.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSLGPTFGRGAMTNSWTDIRNTDLVVIMGGNAAEAHPCGFKWVVEAKANRGAKLVVVDP
CCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCEEEEEEECCCCCCEEEEECC
RFTRSAAVADYYAPIRQGSDIAFLLGVINYCIQNNKVQWDYVKAFTNATYLVKDGFEYRD
CCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHCCCEEEEECCCCCCC
GLFTGYDEEKRDYNRSTWDYQIGPDGYAMVDETLENPRCVWNLLKAHVAQYTPEMVERIS
CCCCCCCHHHHHCCCCCCEEEECCCCHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHC
GTPKDKFLKVAAMIAECSSPTKTMTSMYALGWTQHSKGSQNIRCMAMLQLILGNIGVRGG
CCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCC
GMNALRGHSNIQGLTDIGLMSNMIPGYLNLPTEREPDFATYMSTRGFKPLRPNQMSYWQN
CCHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCHHHHHHH
YKKFMVSFLKSMWGPAATAENNFAFDWLPKLDVPTYDILRAFELMKQGKMNLYFCQGFNP
HHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCH
LQAFPNRNKLSAALSRLKMLVIMDPLETETARFWENHGVYNDVDPSKIQTEVIQLPTTCF
HHHCCCCHHHHHHHHHHEEEEEECCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCEE
AEDEGSLVNSGRWLQWHWPAGSPPGEARTDAWIMSQIHLRLKEMYRKEGGALPDPIVNLS
ECCCCCEECCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEE
WTYKNPDEPTPEELTKELNGYVVSDVLDPNDPTKKLLTAGKQVPNFGVLRDDGSTAAGCW
EEECCCCCCCHHHHHHHHCCEEEEECCCCCCHHHHHHHCCCCCCCCCEEECCCCCEEEEE
IYSGSFTEDGNMMARRDNSDPDNTGAYLKWSFAWPANRRIIYNRASADINGKPWDDTRKL
EEECCCCCCCCEEEECCCCCCCCCCCEEEEEEECCCCCEEEEEECCCCCCCCCCCCCCEE
LWWDGAKWTGYDVPDIAPTAKPQDVGPFIMNPEGVSRLFARGMMRDGPFPVHYEPFESPL
EEECCCCCCCCCCCCCCCCCCCCCCCCEEECHHHHHHHHHHHHCCCCCCCCCCCCCCCCH
VNVIAPKVRGNPVARVFKDDFAQFAEPASKEFPYAATSYRLTEHFHYWTKNNHVNSVLQP
HHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHEEHHHHEEEECCCCCCCCCCCC
EFFVEISEELAKEKSINNGGWVRVWSKRGSVFAKAYVTKRIRPLICDGKPVHVVGIPIHW
HHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEHHHHHHHCCCEEEECCCEEEEEEEEEEE
GFVGAAKKGFPANVLTPFVGDANIETPEFKAFLVNIEPTTGPVA
CEECCCCCCCCCHHCCCCCCCCCCCCCCEEEEEEEECCCCCCCC
>Mature Secondary Structure 
SSLGPTFGRGAMTNSWTDIRNTDLVVIMGGNAAEAHPCGFKWVVEAKANRGAKLVVVDP
CCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCEEEEEEECCCCCCEEEEECC
RFTRSAAVADYYAPIRQGSDIAFLLGVINYCIQNNKVQWDYVKAFTNATYLVKDGFEYRD
CCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHCCCEEEEECCCCCCC
GLFTGYDEEKRDYNRSTWDYQIGPDGYAMVDETLENPRCVWNLLKAHVAQYTPEMVERIS
CCCCCCCHHHHHCCCCCCEEEECCCCHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHC
GTPKDKFLKVAAMIAECSSPTKTMTSMYALGWTQHSKGSQNIRCMAMLQLILGNIGVRGG
CCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCC
GMNALRGHSNIQGLTDIGLMSNMIPGYLNLPTEREPDFATYMSTRGFKPLRPNQMSYWQN
CCHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCHHHHHHH
YKKFMVSFLKSMWGPAATAENNFAFDWLPKLDVPTYDILRAFELMKQGKMNLYFCQGFNP
HHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCH
LQAFPNRNKLSAALSRLKMLVIMDPLETETARFWENHGVYNDVDPSKIQTEVIQLPTTCF
HHHCCCCHHHHHHHHHHEEEEEECCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCEE
AEDEGSLVNSGRWLQWHWPAGSPPGEARTDAWIMSQIHLRLKEMYRKEGGALPDPIVNLS
ECCCCCEECCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEE
WTYKNPDEPTPEELTKELNGYVVSDVLDPNDPTKKLLTAGKQVPNFGVLRDDGSTAAGCW
EEECCCCCCCHHHHHHHHCCEEEEECCCCCCHHHHHHHCCCCCCCCCEEECCCCCEEEEE
IYSGSFTEDGNMMARRDNSDPDNTGAYLKWSFAWPANRRIIYNRASADINGKPWDDTRKL
EEECCCCCCCCEEEECCCCCCCCCCCEEEEEEECCCCCEEEEEECCCCCCCCCCCCCCEE
LWWDGAKWTGYDVPDIAPTAKPQDVGPFIMNPEGVSRLFARGMMRDGPFPVHYEPFESPL
EEECCCCCCCCCCCCCCCCCCCCCCCCEEECHHHHHHHHHHHHCCCCCCCCCCCCCCCCH
VNVIAPKVRGNPVARVFKDDFAQFAEPASKEFPYAATSYRLTEHFHYWTKNNHVNSVLQP
HHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHEEHHHHEEEECCCCCCCCCCCC
EFFVEISEELAKEKSINNGGWVRVWSKRGSVFAKAYVTKRIRPLICDGKPVHVVGIPIHW
HHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEHHHHHHHCCCEEEECCCEEEEEEEEEEE
GFVGAAKKGFPANVLTPFVGDANIETPEFKAFLVNIEPTTGPVA
CEECCCCCCCCCHHCCCCCCCCCCCCCCEEEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8346018; 9278503; 8522521 [H]