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The map label for this gene is paaG [C]

Identifier: 158422556

GI number: 158422556

Start: 1044825

End: 1045748

Strand: Direct

Name: paaG [C]

Synonym: AZC_0932

Alternate gene names: 158422556

Gene position: 1044825-1045748 (Clockwise)

Preceding gene: 158422553

Following gene: 158422557

Centisome position: 19.46

GC content: 70.56

Gene sequence:

>924_bases
GTGGCGGGCAGGCCGGCCCTCGGCAAGGGCGGTCCACGGCGCAAGGCTGCGGCGCACCGGCACTTGCCGCGCCCCCGCGC
TTTGGTGCAGCGTTCACCCCAAGGCGGCCGCATGAGCCGCGGGAGGGAACAGATGTCTAACGCCGATCCGGTGCTGCTCG
ATGTGACGGGCGGCATTGCCCGCATCCGCTTCAACAGACCCCACGTGCTGAATGCGCTCGATGAGCATTCCATCCTCGCC
TTCAAGCGCGCGGTGGAGACGGTGGCGGAGCAGCCCGGCATCCGCGTCGTCGTGCTCTCGGGGGAGGGACGGGCCTTTCT
CGCCGGCGGCGATGTGGCGAGCTTCCACAAGGCGGGGCCGGAGGCGCCGCATCTCGTGGCGGCGCTCATCGGCCCGTTCC
ATGAGGCGCTCGAGATCCTGACGAAGCTCAAGGCGCCGGTCATCGCCAGCGTCCAGGGCGCGGCAGCGGGCGGCGGCCTC
TCGGTGGCGCTGGCGGCGGATCTGCTGATCGCTGCCGACAATGCGCAATTCTCCATGGCCTACAGCCGCATCGCCACCAG
CCCGGACGGCGGCGGGACCTGGCACCTGCCGCGCCTCGTCGGCCTGCGCAAGGCGATGGAACTGGCCCTGCTGTCGGACA
TGGTCGATGCGCAGGAGGCCCTGCGGCTGGGAATCGCCAACAAGGTGGTGCCGCTCGCGGATCTCGCCGAGGAGACGGAG
AAACTCGCCGCCTGCCTCGCCGCTGGTCCCACCGCCGCCTATGGACGCATCAAGGCCCTGCTGCGCGGCGCGGAAACCCA
CAGCCTCACCGAGCAACTGGCGGCGGAGAAGGAGGCCTTCGTCGCAAGCGCCGGAACGCACGATTTCGCCGAGGGTGTCG
CTGCCTTCGTCGCCAAGCGCCTGCCCCGCTTCGAGGGGCACTGA

Upstream 100 bases:

>100_bases
CGGCCTGAAAGCGTGTCGGGAACGGGCATCGAATTTCTCCCAGCCGGCCGCCGCTCCGGCGGCCCCTCCTGGCCGATCTG
TGCCGGCCTGAGCCGATACT

Downstream 100 bases:

>100_bases
CCCGGCGCACGCCGGGCGAACCATAAGAACAGCGGGGAGAAGGCCATGGATGTGAAGGGACATGCCGCCGTCGTCACCGG
CGCGGCGTCGGGGCTCGGCG

Product: enoyl-CoA hydratase/isomerase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 307; Mature: 306

Protein sequence:

>307_residues
MAGRPALGKGGPRRKAAAHRHLPRPRALVQRSPQGGRMSRGREQMSNADPVLLDVTGGIARIRFNRPHVLNALDEHSILA
FKRAVETVAEQPGIRVVVLSGEGRAFLAGGDVASFHKAGPEAPHLVAALIGPFHEALEILTKLKAPVIASVQGAAAGGGL
SVALAADLLIAADNAQFSMAYSRIATSPDGGGTWHLPRLVGLRKAMELALLSDMVDAQEALRLGIANKVVPLADLAEETE
KLAACLAAGPTAAYGRIKALLRGAETHSLTEQLAAEKEAFVASAGTHDFAEGVAAFVAKRLPRFEGH

Sequences:

>Translated_307_residues
MAGRPALGKGGPRRKAAAHRHLPRPRALVQRSPQGGRMSRGREQMSNADPVLLDVTGGIARIRFNRPHVLNALDEHSILA
FKRAVETVAEQPGIRVVVLSGEGRAFLAGGDVASFHKAGPEAPHLVAALIGPFHEALEILTKLKAPVIASVQGAAAGGGL
SVALAADLLIAADNAQFSMAYSRIATSPDGGGTWHLPRLVGLRKAMELALLSDMVDAQEALRLGIANKVVPLADLAEETE
KLAACLAAGPTAAYGRIKALLRGAETHSLTEQLAAEKEAFVASAGTHDFAEGVAAFVAKRLPRFEGH
>Mature_306_residues
AGRPALGKGGPRRKAAAHRHLPRPRALVQRSPQGGRMSRGREQMSNADPVLLDVTGGIARIRFNRPHVLNALDEHSILAF
KRAVETVAEQPGIRVVVLSGEGRAFLAGGDVASFHKAGPEAPHLVAALIGPFHEALEILTKLKAPVIASVQGAAAGGGLS
VALAADLLIAADNAQFSMAYSRIATSPDGGGTWHLPRLVGLRKAMELALLSDMVDAQEALRLGIANKVVPLADLAEETEK
LAACLAAGPTAAYGRIKALLRGAETHSLTEQLAAEKEAFVASAGTHDFAEGVAAFVAKRLPRFEGH

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=246, Percent_Identity=34.5528455284553, Blast_Score=139, Evalue=4e-33,
Organism=Homo sapiens, GI4502327, Length=260, Percent_Identity=30, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI45643119, Length=275, Percent_Identity=24.7272727272727, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI260275230, Length=275, Percent_Identity=24.7272727272727, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI260274832, Length=275, Percent_Identity=24.7272727272727, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI31542718, Length=282, Percent_Identity=26.241134751773, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI37594469, Length=209, Percent_Identity=28.2296650717703, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI37594471, Length=209, Percent_Identity=28.2296650717703, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI70995211, Length=247, Percent_Identity=25.1012145748988, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI68989263, Length=192, Percent_Identity=31.25, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI20127408, Length=180, Percent_Identity=26.6666666666667, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1787660, Length=258, Percent_Identity=37.984496124031, Blast_Score=145, Evalue=5e-36,
Organism=Escherichia coli, GI1788597, Length=255, Percent_Identity=33.3333333333333, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI221142681, Length=258, Percent_Identity=32.1705426356589, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI1787659, Length=247, Percent_Identity=31.9838056680162, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI87082183, Length=257, Percent_Identity=29.5719844357977, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI1790281, Length=194, Percent_Identity=26.2886597938144, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788682, Length=192, Percent_Identity=30.2083333333333, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI25145438, Length=247, Percent_Identity=34.0080971659919, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17554946, Length=248, Percent_Identity=32.258064516129, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17560910, Length=206, Percent_Identity=32.0388349514563, Blast_Score=100, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI17535521, Length=261, Percent_Identity=24.5210727969349, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17540714, Length=225, Percent_Identity=29.3333333333333, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17536985, Length=261, Percent_Identity=25.6704980842912, Blast_Score=87, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17549921, Length=193, Percent_Identity=26.4248704663212, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17558304, Length=190, Percent_Identity=25.7894736842105, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17534483, Length=256, Percent_Identity=24.21875, Blast_Score=71, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI25144157, Length=255, Percent_Identity=24.7058823529412, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI25144160, Length=255, Percent_Identity=24.7058823529412, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI25144276, Length=213, Percent_Identity=27.6995305164319, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17508951, Length=213, Percent_Identity=27.6995305164319, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17508953, Length=247, Percent_Identity=26.3157894736842, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6320241, Length=201, Percent_Identity=29.3532338308458, Blast_Score=82, Evalue=9e-17,
Organism=Drosophila melanogaster, GI20129971, Length=287, Percent_Identity=31.7073170731707, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24653477, Length=287, Percent_Identity=31.7073170731707, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24653139, Length=306, Percent_Identity=31.3725490196078, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI19922422, Length=258, Percent_Identity=24.031007751938, Blast_Score=88, Evalue=8e-18,
Organism=Drosophila melanogaster, GI21357171, Length=247, Percent_Identity=26.3157894736842, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24654903, Length=250, Percent_Identity=21.2, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI19920382, Length=252, Percent_Identity=25.3968253968254, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI28571730, Length=149, Percent_Identity=30.8724832214765, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI28571729, Length=149, Percent_Identity=30.8724832214765, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 32104; Mature: 31973

Theoretical pI: Translated: 10.27; Mature: 10.27

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGRPALGKGGPRRKAAAHRHLPRPRALVQRSPQGGRMSRGREQMSNADPVLLDVTGGIA
CCCCCCCCCCCCHHHHHHHHCCCCCHHHHHCCCCCCCHHHHHHHHCCCCCEEEEECCCEE
RIRFNRPHVLNALDEHSILAFKRAVETVAEQPGIRVVVLSGEGRAFLAGGDVASFHKAGP
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEECCCHHHHHHCCC
EAPHLVAALIGPFHEALEILTKLKAPVIASVQGAAAGGGLSVALAADLLIAADNAQFSMA
CCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHHHEEECCCHHHHH
YSRIATSPDGGGTWHLPRLVGLRKAMELALLSDMVDAQEALRLGIANKVVPLADLAEETE
HHHHCCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
KLAACLAAGPTAAYGRIKALLRGAETHSLTEQLAAEKEAFVASAGTHDFAEGVAAFVAKR
HHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
LPRFEGH
CCCCCCC
>Mature Secondary Structure 
AGRPALGKGGPRRKAAAHRHLPRPRALVQRSPQGGRMSRGREQMSNADPVLLDVTGGIA
CCCCCCCCCCCHHHHHHHHCCCCCHHHHHCCCCCCCHHHHHHHHCCCCCEEEEECCCEE
RIRFNRPHVLNALDEHSILAFKRAVETVAEQPGIRVVVLSGEGRAFLAGGDVASFHKAGP
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEECCCHHHHHHCCC
EAPHLVAALIGPFHEALEILTKLKAPVIASVQGAAAGGGLSVALAADLLIAADNAQFSMA
CCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHHHEEECCCHHHHH
YSRIATSPDGGGTWHLPRLVGLRKAMELALLSDMVDAQEALRLGIANKVVPLADLAEETE
HHHHCCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
KLAACLAAGPTAAYGRIKALLRGAETHSLTEQLAAEKEAFVASAGTHDFAEGVAAFVAKR
HHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
LPRFEGH
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA