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The map label for this gene is fmt [H]

Identifier: 158422421

GI number: 158422421

Start: 900187

End: 901110

Strand: Reverse

Name: fmt [H]

Synonym: AZC_0797

Alternate gene names: 158422421

Gene position: 901110-900187 (Counterclockwise)

Preceding gene: 158422422

Following gene: 158422420

Centisome position: 16.78

GC content: 70.24

Gene sequence:

>924_bases
ATGCGCATCGTCTTCATGGGCACGCCCGATTTCTCGGTGCCCACCCTGAGCGAGATCGTCGGCCGCGGGCACGAGGTGGT
GGGGGTCTATACCCGCGCACCCGCGCCCTCGGGCCGCCGCGGCCTCGAACTCGTCCCCTCGCCCGTCCACACGGTGGCGG
AGCGCTTCGGCATCCCGGTCTTCACGCCGAAATCGCTGAAGGGCGAGGAGGCTGCCGCGCAGTTCCGTGAGCTCGGCGCG
GACGTGGCGGTGGTGGTCGCCTATGGCCTCATCCTGCCGACCAGCATCCTCGACATTCCGGCGCTGGGCTGCCTGAACCT
CCATGCTTCGCTGCTGCCTCGCTGGCGCGGCGCCGCGCCCATCCAGCGGGCCATCATGGCGGGGGACAAGGAAACCGGCA
TCGCCGTCATGAAGATGGAAGCCGGGCTCGACACGGGCCCGGTGGGCCTGCTGGAGCGCGTCATCATCGGCCCCGACATG
ACGGCCGGCGAACTGCACGATCGCCTGAGCTATATCGGCGCCGACCTCATGGGCCGCGCGCTCTCGGCGCTGGAACGGGG
CGGGCTCGATTTCACGCCGCAGCCGGACGAGGGCATCGTCTATGCGTCCAAGATCGAGAAGGCGGAAGCCCGCATCGACT
GGAGCCGGCCGGCGGCGGAGGTGCACAACACCATTCGCGGCCTCTCCCCTTTCCCCGGCGCCTGGTTCCCCTTCGGAGCC
GACGAGGCGCGGGTGAAGGTGCTGCGTGCTTCTCTTGCGGACGGCACGGGCGCGCCGGGGACGGCGCTCGACGACCAGCT
CACCATCGCCTGCGGCACCGGCGCCGTGCGGCTGACGGAGCTCCAGAAGGCCGGCAAGCAGCCCATGAGCGCCGCCACAT
TCCTCAATGGCAATGACGTGCCCAAGGGCACGCGGCTGGCCTGA

Upstream 100 bases:

>100_bases
CGGCTGAAGCGAGAGCGGGTCATCAAGAAATTCACCAAGGCCGCCCGCCGCGAAGCCGGCGCCTGACGCGCCCTCCTCTC
CTCTGAACAGGTTTCGCGCC

Downstream 100 bases:

>100_bases
GCCGGCCGGTTCCGCCCCCACCATGCCCCGCTACAAGCTCACCATCGAATATGACGGCACCCCCTTCGCCGGCTGGCAGA
TCCAGGCGGAGCTGCCGACC

Product: methionyl-tRNA formyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MRIVFMGTPDFSVPTLSEIVGRGHEVVGVYTRAPAPSGRRGLELVPSPVHTVAERFGIPVFTPKSLKGEEAAAQFRELGA
DVAVVVAYGLILPTSILDIPALGCLNLHASLLPRWRGAAPIQRAIMAGDKETGIAVMKMEAGLDTGPVGLLERVIIGPDM
TAGELHDRLSYIGADLMGRALSALERGGLDFTPQPDEGIVYASKIEKAEARIDWSRPAAEVHNTIRGLSPFPGAWFPFGA
DEARVKVLRASLADGTGAPGTALDDQLTIACGTGAVRLTELQKAGKQPMSAATFLNGNDVPKGTRLA

Sequences:

>Translated_307_residues
MRIVFMGTPDFSVPTLSEIVGRGHEVVGVYTRAPAPSGRRGLELVPSPVHTVAERFGIPVFTPKSLKGEEAAAQFRELGA
DVAVVVAYGLILPTSILDIPALGCLNLHASLLPRWRGAAPIQRAIMAGDKETGIAVMKMEAGLDTGPVGLLERVIIGPDM
TAGELHDRLSYIGADLMGRALSALERGGLDFTPQPDEGIVYASKIEKAEARIDWSRPAAEVHNTIRGLSPFPGAWFPFGA
DEARVKVLRASLADGTGAPGTALDDQLTIACGTGAVRLTELQKAGKQPMSAATFLNGNDVPKGTRLA
>Mature_307_residues
MRIVFMGTPDFSVPTLSEIVGRGHEVVGVYTRAPAPSGRRGLELVPSPVHTVAERFGIPVFTPKSLKGEEAAAQFRELGA
DVAVVVAYGLILPTSILDIPALGCLNLHASLLPRWRGAAPIQRAIMAGDKETGIAVMKMEAGLDTGPVGLLERVIIGPDM
TAGELHDRLSYIGADLMGRALSALERGGLDFTPQPDEGIVYASKIEKAEARIDWSRPAAEVHNTIRGLSPFPGAWFPFGA
DEARVKVLRASLADGTGAPGTALDDQLTIACGTGAVRLTELQKAGKQPMSAATFLNGNDVPKGTRLA

Specific function: Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by:(I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-

COG id: COG0223

COG function: function code J; Methionyl-tRNA formyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fmt family [H]

Homologues:

Organism=Homo sapiens, GI21614513, Length=241, Percent_Identity=33.195020746888, Blast_Score=130, Evalue=1e-30,
Organism=Homo sapiens, GI238814322, Length=241, Percent_Identity=34.4398340248963, Blast_Score=129, Evalue=3e-30,
Organism=Homo sapiens, GI164663775, Length=325, Percent_Identity=28.9230769230769, Blast_Score=96, Evalue=5e-20,
Organism=Escherichia coli, GI1789683, Length=301, Percent_Identity=45.8471760797342, Blast_Score=251, Evalue=3e-68,
Organism=Escherichia coli, GI1788589, Length=309, Percent_Identity=26.537216828479, Blast_Score=121, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI133930964, Length=249, Percent_Identity=30.9236947791165, Blast_Score=113, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6319458, Length=284, Percent_Identity=26.4084507042254, Blast_Score=71, Evalue=2e-13,
Organism=Drosophila melanogaster, GI45550868, Length=304, Percent_Identity=31.25, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI28571984, Length=225, Percent_Identity=32.8888888888889, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24585660, Length=237, Percent_Identity=27.8481012658228, Blast_Score=94, Evalue=8e-20,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005794
- InterPro:   IPR005793
- InterPro:   IPR002376
- InterPro:   IPR011034
- InterPro:   IPR015518 [H]

Pfam domain/function: PF02911 Formyl_trans_C; PF00551 Formyl_trans_N [H]

EC number: =2.1.2.9 [H]

Molecular weight: Translated: 32349; Mature: 32349

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIVFMGTPDFSVPTLSEIVGRGHEVVGVYTRAPAPSGRRGLELVPSPVHTVAERFGIPV
CEEEEECCCCCCCCHHHHHHCCCCEEEEEEECCCCCCCCCCCEECCCHHHHHHHHHCCCC
FTPKSLKGEEAAAQFRELGADVAVVVAYGLILPTSILDIPALGCLNLHASLLPRWRGAAP
CCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHH
IQRAIMAGDKETGIAVMKMEAGLDTGPVGLLERVIIGPDMTAGELHDRLSYIGADLMGRA
HHHHHHCCCCCCCEEEEEEECCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
LSALERGGLDFTPQPDEGIVYASKIEKAEARIDWSRPAAEVHNTIRGLSPFPGAWFPFGA
HHHHHHCCCCCCCCCCCCEEEHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCC
DEARVKVLRASLADGTGAPGTALDDQLTIACGTGAVRLTELQKAGKQPMSAATFLNGNDV
CHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCEEHHHHHHCCCCCCCCEEEECCCCC
PKGTRLA
CCCCCCC
>Mature Secondary Structure
MRIVFMGTPDFSVPTLSEIVGRGHEVVGVYTRAPAPSGRRGLELVPSPVHTVAERFGIPV
CEEEEECCCCCCCCHHHHHHCCCCEEEEEEECCCCCCCCCCCEECCCHHHHHHHHHCCCC
FTPKSLKGEEAAAQFRELGADVAVVVAYGLILPTSILDIPALGCLNLHASLLPRWRGAAP
CCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHH
IQRAIMAGDKETGIAVMKMEAGLDTGPVGLLERVIIGPDMTAGELHDRLSYIGADLMGRA
HHHHHHCCCCCCCEEEEEEECCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
LSALERGGLDFTPQPDEGIVYASKIEKAEARIDWSRPAAEVHNTIRGLSPFPGAWFPFGA
HHHHHHCCCCCCCCCCCCEEEHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCC
DEARVKVLRASLADGTGAPGTALDDQLTIACGTGAVRLTELQKAGKQPMSAATFLNGNDV
CHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCEEHHHHHHCCCCCCCCEEEECCCCC
PKGTRLA
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA