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The map label for this gene is asd

Identifier: 15836579

GI number: 15836579

Start: 1198009

End: 1199010

Strand: Direct

Name: asd

Synonym: CPj1048

Alternate gene names: 15836579

Gene position: 1198009-1199010 (Clockwise)

Preceding gene: 15836578

Following gene: 15836580

Centisome position: 97.67

GC content: 42.51

Gene sequence:

>1002_bases
ATGCGAATCGCTGTTTTAGGCGTTACTGGACTTGTTGGCCAGAAATTCGTAGCTTTGCTTCATAAGTGGTATCGTGATTG
GGTCATTGCTGAAGTCGTAGCTTCAAATAGTAAATATGGGCAATCGTATGGAGATGCCTGTATTTGGCAGGAGCCAATCG
GCCCTATGCCTGAGATGGTACGTGATTTGCCTATACGTAAGATCGAGGAAGTGCAGTCCGACATCGTTGATTCTTTTTTG
CCTTCTAGTGCTGAGTCCATGGAGGCGTATTGCCTCTCTCAAGGAAAAGTTGTCTTTTCTAATGCCTCAACATATCGCAT
GCATTCTTCAGTTCCTATTATCATCCCTGAAGTCAACTCAGATCATTTTCAACTTTTAGAAGAGCAACCTTATCCTGGGA
AAATAATCACAAGTCCCAATTGTTGTGTCTCTGGAATTACTTTGGCTCTAGCACCCTTAAGAAAGTTCTCCTTAGATCAC
GTACACATTGTCACCTTACAATCAGCAAGTGGTGCAGGCTATCCAGGAGTCCCGTCGCTAGATCTTCTTGCCAATACAGT
TCCTCATATCGTTGGAGAAGAAGAAAAAATTCTTAGAGAGACTGTGAAGATTTTAGGAAGTTCTAAGCAACCTTTACCTT
GTAAGCTCTCTGTGACAGTCCATCGAGTTCCCGTAGCCTACGGTCATACGCTCTCTCTGCATGTTACCTTTTCTAAAGAT
GTAGATCTTGACGAGATTCTGTACTCTTACCAAGAAAAAAATAAAGAATTCCCCAATACCTACCAACTCTATGATAACCC
TTGGTCTCCTCAGGCTCGAAAGCATCTTTCTCACGACGATATGCGCGTACACCTAGGACCCATTACCTACGGAGGAGATT
TTCGCACCATAAAGATGAATGTTTTAATACATAATTTGGTGCGAGGTGCTGCAGGGACTTTACTCGCAAGTATGGAGAAT
TATTTTTTCGACTATCTTAAGAGGGAAATGTGTCTAAGATAG

Upstream 100 bases:

>100_bases
GGCAATTCAAAAGGAATCATTGCATGTCTGTAAACACTAGAGATAGGGTTATCGTGCATTCCAATCTGAAGTAAATAATT
GAGATGGAGAAAGGAAAGGA

Downstream 100 bases:

>100_bases
TTTATAAATTTGGTGGCACTAGCTTAGCAACTGCTGAGAATATCTGTTTGGTTTGTGATATCATTTGCAAAGATAAGCCT
TCTTTTGTTGTTGTAAGCGC

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MRIAVLGVTGLVGQKFVALLHKWYRDWVIAEVVASNSKYGQSYGDACIWQEPIGPMPEMVRDLPIRKIEEVQSDIVDSFL
PSSAESMEAYCLSQGKVVFSNASTYRMHSSVPIIIPEVNSDHFQLLEEQPYPGKIITSPNCCVSGITLALAPLRKFSLDH
VHIVTLQSASGAGYPGVPSLDLLANTVPHIVGEEEKILRETVKILGSSKQPLPCKLSVTVHRVPVAYGHTLSLHVTFSKD
VDLDEILYSYQEKNKEFPNTYQLYDNPWSPQARKHLSHDDMRVHLGPITYGGDFRTIKMNVLIHNLVRGAAGTLLASMEN
YFFDYLKREMCLR

Sequences:

>Translated_333_residues
MRIAVLGVTGLVGQKFVALLHKWYRDWVIAEVVASNSKYGQSYGDACIWQEPIGPMPEMVRDLPIRKIEEVQSDIVDSFL
PSSAESMEAYCLSQGKVVFSNASTYRMHSSVPIIIPEVNSDHFQLLEEQPYPGKIITSPNCCVSGITLALAPLRKFSLDH
VHIVTLQSASGAGYPGVPSLDLLANTVPHIVGEEEKILRETVKILGSSKQPLPCKLSVTVHRVPVAYGHTLSLHVTFSKD
VDLDEILYSYQEKNKEFPNTYQLYDNPWSPQARKHLSHDDMRVHLGPITYGGDFRTIKMNVLIHNLVRGAAGTLLASMEN
YFFDYLKREMCLR
>Mature_333_residues
MRIAVLGVTGLVGQKFVALLHKWYRDWVIAEVVASNSKYGQSYGDACIWQEPIGPMPEMVRDLPIRKIEEVQSDIVDSFL
PSSAESMEAYCLSQGKVVFSNASTYRMHSSVPIIIPEVNSDHFQLLEEQPYPGKIITSPNCCVSGITLALAPLRKFSLDH
VHIVTLQSASGAGYPGVPSLDLLANTVPHIVGEEEKILRETVKILGSSKQPLPCKLSVTVHRVPVAYGHTLSLHVTFSKD
VDLDEILYSYQEKNKEFPNTYQLYDNPWSPQARKHLSHDDMRVHLGPITYGGDFRTIKMNVLIHNLVRGAAGTLLASMEN
YFFDYLKREMCLR

Specific function: This enzyme catalyzes the second step in the common metabolic pathway to synthesize Thr and Met from Asp [H]

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320362, Length=354, Percent_Identity=32.4858757062147, Blast_Score=136, Evalue=4e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR005676
- InterPro:   IPR012080
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 37316; Mature: 37316

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIAVLGVTGLVGQKFVALLHKWYRDWVIAEVVASNSKYGQSYGDACIWQEPIGPMPEMV
CEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCHHHHH
RDLPIRKIEEVQSDIVDSFLPSSAESMEAYCLSQGKVVFSNASTYRMHSSVPIIIPEVNS
HHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEECCCEEEEECCCCEEEECCCC
DHFQLLEEQPYPGKIITSPNCCVSGITLALAPLRKFSLDHVHIVTLQSASGAGYPGVPSL
HHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCH
DLLANTVPHIVGEEEKILRETVKILGSSKQPLPCKLSVTVHRVPVAYGHTLSLHVTFSKD
HHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEEEEECCEEEEEEEECCC
VDLDEILYSYQEKNKEFPNTYQLYDNPWSPQARKHLSHDDMRVHLGPITYGGDFRTIKMN
CCHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHCCCCCCEEEEEEEEECCCEEEEEHH
VLIHNLVRGAAGTLLASMENYFFDYLKREMCLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRIAVLGVTGLVGQKFVALLHKWYRDWVIAEVVASNSKYGQSYGDACIWQEPIGPMPEMV
CEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCHHHHH
RDLPIRKIEEVQSDIVDSFLPSSAESMEAYCLSQGKVVFSNASTYRMHSSVPIIIPEVNS
HHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEECCCEEEEECCCCEEEECCCC
DHFQLLEEQPYPGKIITSPNCCVSGITLALAPLRKFSLDHVHIVTLQSASGAGYPGVPSL
HHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCH
DLLANTVPHIVGEEEKILRETVKILGSSKQPLPCKLSVTVHRVPVAYGHTLSLHVTFSKD
HHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEEEEECCEEEEEEEECCC
VDLDEILYSYQEKNKEFPNTYQLYDNPWSPQARKHLSHDDMRVHLGPITYGGDFRTIKMN
CCHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHCCCCCCEEEEEEEEECCCEEEEEHH
VLIHNLVRGAAGTLLASMENYFFDYLKREMCLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]