Click here to switch to the map view.

The map label for this gene is dapB

Identifier: 15836578

GI number: 15836578

Start: 1196955

End: 1197749

Strand: Direct

Name: dapB

Synonym: CPj1047

Alternate gene names: 15836578

Gene position: 1196955-1197749 (Clockwise)

Preceding gene: 15836560

Following gene: 15836579

Centisome position: 97.59

GC content: 42.39

Gene sequence:

>795_bases
ATGGGGTCGAGTATGCACGTTGGAGTGATTGGCTGTTCTGGAAGAACAGGGAAAGTGATTGTCTCAGCTTTAGAGCAATC
TTCAGAATATACTTTGGGTCCAGGGTTCTCTCGCAGTAGTGCACTCACTCTTTTTCAAGTGATTGCACATAACGATGTTC
TTGTTGATTTTTCCCACCCCTTACTAACTAAAGAAGTCGTTGCCCATCTCTTAATCTCTCCTAAACCCCTCATTATCGGA
ACTACAGGGTTCCCTGGGAAGTGTAAAGAAGCTCATGACAGTCTCGAAGAGCTGACTCACATCGTTCCTGTAGTGGTTTG
TCCAAATGCAAGTCTAGGAGCTTATATACACAAGCGGCTTGTAATGTTGCTATCGCAATTATGTAACCCACAGTTTGATA
TTCGCATTCGCGAGACTCATCATAGATATAAGAAGGACTCTCTCTCAGGAACAGCTCAAGATTTACTTGATACTATACAG
CAAGTAAAACAAGAGGATTGGGGAGAGGAGTATGAGGTAGGCCAGCGAGATTCTTCTAAGAAGACGATAGAAGTGCAATC
TTCACGAGTTGGAGATATCCCTGGAGAACATGAGGTCGCTTTTATCAGTTCTGGAGAGCAAATTTTGGTTCGCCACACAG
TATTTTCTCGCAATGTTTTTGGTCGGGGAATCCTTTCTATTTTAGATTGGCTAAAAACATTGAATCCCCAACCTGGTTTG
TATAGTCTTGGGGATACTTTGGAGCTAGTCTTACGAAATGAACATTGCTTGCTTAAAAAGACAACGGATCATTAA

Upstream 100 bases:

>100_bases
AGTAAGTTTTTGAAAAATTCTAAAATAGAAATGCATTTGTGTCGAGCTAAAGCTTGCTTCTCTTTATTTTCCTTTTGTAG
AATGATTCGGTAGTAGGAAT

Downstream 100 bases:

>100_bases
TATGCAGATATAAAGATCTTTTGCGTCGTAAAATCCTGATCTTCAAATTAGGAATGTAGGGTGCCGCAATTACACAACTT
CGTGTACAAAATTTTAAGCG

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR

Number of amino acids: Translated: 264; Mature: 263

Protein sequence:

>264_residues
MGSSMHVGVIGCSGRTGKVIVSALEQSSEYTLGPGFSRSSALTLFQVIAHNDVLVDFSHPLLTKEVVAHLLISPKPLIIG
TTGFPGKCKEAHDSLEELTHIVPVVVCPNASLGAYIHKRLVMLLSQLCNPQFDIRIRETHHRYKKDSLSGTAQDLLDTIQ
QVKQEDWGEEYEVGQRDSSKKTIEVQSSRVGDIPGEHEVAFISSGEQILVRHTVFSRNVFGRGILSILDWLKTLNPQPGL
YSLGDTLELVLRNEHCLLKKTTDH

Sequences:

>Translated_264_residues
MGSSMHVGVIGCSGRTGKVIVSALEQSSEYTLGPGFSRSSALTLFQVIAHNDVLVDFSHPLLTKEVVAHLLISPKPLIIG
TTGFPGKCKEAHDSLEELTHIVPVVVCPNASLGAYIHKRLVMLLSQLCNPQFDIRIRETHHRYKKDSLSGTAQDLLDTIQ
QVKQEDWGEEYEVGQRDSSKKTIEVQSSRVGDIPGEHEVAFISSGEQILVRHTVFSRNVFGRGILSILDWLKTLNPQPGL
YSLGDTLELVLRNEHCLLKKTTDH
>Mature_263_residues
GSSMHVGVIGCSGRTGKVIVSALEQSSEYTLGPGFSRSSALTLFQVIAHNDVLVDFSHPLLTKEVVAHLLISPKPLIIGT
TGFPGKCKEAHDSLEELTHIVPVVVCPNASLGAYIHKRLVMLLSQLCNPQFDIRIRETHHRYKKDSLSGTAQDLLDTIQQ
VKQEDWGEEYEVGQRDSSKKTIEVQSSRVGDIPGEHEVAFISSGEQILVRHTVFSRNVFGRGILSILDWLKTLNPQPGLY
SLGDTLELVLRNEHCLLKKTTDH

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family

Homologues:

Organism=Escherichia coli, GI1786214, Length=274, Percent_Identity=27.3722627737226, Blast_Score=89, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DAPB_CHLPN (Q9Z6L2)

Other databases:

- EMBL:   AE001363
- EMBL:   AE002161
- EMBL:   BA000008
- EMBL:   AE009440
- PIR:   D86621
- PIR:   F72002
- RefSeq:   NP_225241.1
- RefSeq:   NP_301102.1
- RefSeq:   NP_445344.1
- RefSeq:   NP_877359.1
- ProteinModelPortal:   Q9Z6L2
- SMR:   Q9Z6L2
- GeneID:   1467766
- GeneID:   894756
- GeneID:   919816
- GeneID:   962718
- GenomeReviews:   AE001363_GR
- GenomeReviews:   AE002161_GR
- GenomeReviews:   AE009440_GR
- GenomeReviews:   BA000008_GR
- KEGG:   cpa:CP0805
- KEGG:   cpn:CPn1047
- KEGG:   cpt:CpB1088
- TIGR:   CP_0805
- HOGENOM:   HBG594002
- OMA:   SRDIFAK
- ProtClustDB:   PRK00048
- BioCyc:   CPNE115711:CP_0805-MONOMER
- BioCyc:   CPNE115713:CPN1047-MONOMER
- BioCyc:   CPNE138677:CPJ1047-MONOMER
- BioCyc:   CPNE182082:CPB1088-MONOMER
- BRENDA:   1.3.1.26
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00102
- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR20836
- TIGRFAMs:   TIGR00036

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N

EC number: =1.3.1.26

Molecular weight: Translated: 29184; Mature: 29053

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSSMHVGVIGCSGRTGKVIVSALEQSSEYTLGPGFSRSSALTLFQVIAHNDVLVDFSHP
CCCCEEEEEEECCCCCHHHHHHHHHCCCCEECCCCCCCHHHHHHHHHHHCCCEEEECCCC
LLTKEVVAHLLISPKPLIIGTTGFPGKCKEAHDSLEELTHIVPVVVCPNASLGAYIHKRL
HHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHH
VMLLSQLCNPQFDIRIRETHHRYKKDSLSGTAQDLLDTIQQVKQEDWGEEYEVGQRDSSK
HHHHHHHCCCCEEEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHCCCCCCCCC
KTIEVQSSRVGDIPGEHEVAFISSGEQILVRHTVFSRNVFGRGILSILDWLKTLNPQPGL
CEEEEECCCCCCCCCCCEEEEECCCCEEEEEEHHHHCCHHHHHHHHHHHHHHHCCCCCCC
YSLGDTLELVLRNEHCLLKKTTDH
CHHCHHHHHHHCCCCEEEEECCCC
>Mature Secondary Structure 
GSSMHVGVIGCSGRTGKVIVSALEQSSEYTLGPGFSRSSALTLFQVIAHNDVLVDFSHP
CCCEEEEEEECCCCCHHHHHHHHHCCCCEECCCCCCCHHHHHHHHHHHCCCEEEECCCC
LLTKEVVAHLLISPKPLIIGTTGFPGKCKEAHDSLEELTHIVPVVVCPNASLGAYIHKRL
HHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHH
VMLLSQLCNPQFDIRIRETHHRYKKDSLSGTAQDLLDTIQQVKQEDWGEEYEVGQRDSSK
HHHHHHHCCCCEEEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHCCCCCCCCC
KTIEVQSSRVGDIPGEHEVAFISSGEQILVRHTVFSRNVFGRGILSILDWLKTLNPQPGL
CEEEEECCCCCCCCCCCEEEEECCCCEEEEEEHHHHCCHHHHHHHHHHHHHHHCCCCCCC
YSLGDTLELVLRNEHCLLKKTTDH
CHHCHHHHHHHCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362