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The map label for this gene is dapB

Identifier: 15835258

GI number: 15835258

Start: 769123

End: 769863

Strand: Reverse

Name: dapB

Synonym: TC0643

Alternate gene names: 15835258

Gene position: 769863-769123 (Counterclockwise)

Preceding gene: 15835259

Following gene: 15835257

Centisome position: 71.75

GC content: 40.89

Gene sequence:

>741_bases
ATGAAAAAAAGCGTGGGTCTTATTGGAAATACTGGGAGGATGGGGGGGCTGTTAACAGAAGCGTTGCGTTCTCACCCTCG
TTGTCTTTTGGGGAAGGGATTTTCAAGAAGATCGCAGACTTTGTTGAAAGAAGTCGTTTTAGAAAATGATATTCTTATAG
ACTTTTCAGCTCCTGAAGTTACAGAAACGCTTATGGATATTTTATTGGTAACGCCTAAGCCTGTAATTATTGGAACCACA
GGATTTTCCGATAATAGCGTTATTAGGGACAAATTGTCTTTGTTATCGGAATATGTTCCTGTCATTTTTAGCCCAAACAT
GAGTTTGGGCGCCTATGTGCAGAGAAGACTAACTGCTTGTGCGGCTAAGTTATTCGATGCTTCTTATGATGTACGTATCT
TAGAGACTCATCATCGCACGAAGGTAGATGCCATTTCTGGTACAGCACTTTCGTTAGCAGAGGCTATCTGCTCTGCAAAA
AAAGACCATTTTGGGGATGAGCAGGAACCTTGTATCGAGATGTTCGGTTCTCGTGTCGGCAACATTTTTGGAGAACACGA
AGTATCTTTTGTGGGGAAAAACGAGCGTTTTGTTATTCGTCATGAGGCCTTCTCTCGGCAGACTTTTTCTGATGGAGTGC
TGATCATTTTAAGGAAAATTATGGAAGAAAGGTTGCCTGCAGGGTATTACACTTCTGATGTTTTGTATGAAAGTCTATTT
CAGGAAGTTGTTTTTGATTAA

Upstream 100 bases:

>100_bases
CTAACTTATATTATACTCCGGCCGTTTCGTTTAAAGATTGGCTATTGAAGGAAGATCCTTTAGTTAGCAGAGAACGTAGA
TTAGAGTTGCTGACAGTATT

Downstream 100 bases:

>100_bases
GAGCTAAAGGTGACGATGCGCATTGCAATTTTGGGTGCTACAGGCCTTGTCGGACAAAAGCTAATCGCTTTGTTACAAAG
GCATAAGCAGTGGGAGATTG

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MKKSVGLIGNTGRMGGLLTEALRSHPRCLLGKGFSRRSQTLLKEVVLENDILIDFSAPEVTETLMDILLVTPKPVIIGTT
GFSDNSVIRDKLSLLSEYVPVIFSPNMSLGAYVQRRLTACAAKLFDASYDVRILETHHRTKVDAISGTALSLAEAICSAK
KDHFGDEQEPCIEMFGSRVGNIFGEHEVSFVGKNERFVIRHEAFSRQTFSDGVLIILRKIMEERLPAGYYTSDVLYESLF
QEVVFD

Sequences:

>Translated_246_residues
MKKSVGLIGNTGRMGGLLTEALRSHPRCLLGKGFSRRSQTLLKEVVLENDILIDFSAPEVTETLMDILLVTPKPVIIGTT
GFSDNSVIRDKLSLLSEYVPVIFSPNMSLGAYVQRRLTACAAKLFDASYDVRILETHHRTKVDAISGTALSLAEAICSAK
KDHFGDEQEPCIEMFGSRVGNIFGEHEVSFVGKNERFVIRHEAFSRQTFSDGVLIILRKIMEERLPAGYYTSDVLYESLF
QEVVFD
>Mature_246_residues
MKKSVGLIGNTGRMGGLLTEALRSHPRCLLGKGFSRRSQTLLKEVVLENDILIDFSAPEVTETLMDILLVTPKPVIIGTT
GFSDNSVIRDKLSLLSEYVPVIFSPNMSLGAYVQRRLTACAAKLFDASYDVRILETHHRTKVDAISGTALSLAEAICSAK
KDHFGDEQEPCIEMFGSRVGNIFGEHEVSFVGKNERFVIRHEAFSRQTFSDGVLIILRKIMEERLPAGYYTSDVLYESLF
QEVVFD

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family

Homologues:

Organism=Escherichia coli, GI1786214, Length=243, Percent_Identity=31.2757201646091, Blast_Score=103, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DAPB_CHLMU (Q9PK30)

Other databases:

- EMBL:   AE002160
- PIR:   C81679
- RefSeq:   NP_297017.1
- ProteinModelPortal:   Q9PK30
- SMR:   Q9PK30
- GeneID:   1246004
- GenomeReviews:   AE002160_GR
- KEGG:   cmu:TC0643
- TIGR:   TC_0643
- HOGENOM:   HBG594002
- OMA:   GALKACE
- PhylomeDB:   Q9PK30
- ProtClustDB:   PRK00048
- BioCyc:   CMUR243161:TC_0643-MONOMER
- BRENDA:   1.3.1.26
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00102
- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR20836
- TIGRFAMs:   TIGR00036

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N

EC number: =1.3.1.26

Molecular weight: Translated: 27397; Mature: 27397

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKSVGLIGNTGRMGGLLTEALRSHPRCLLGKGFSRRSQTLLKEVVLENDILIDFSAPEV
CCCCCCCCCCCCCHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHCCCEEEECCCCHH
TETLMDILLVTPKPVIIGTTGFSDNSVIRDKLSLLSEYVPVIFSPNMSLGAYVQRRLTAC
HHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCEEECCCCCHHHHHHHHHHHH
AAKLFDASYDVRILETHHRTKVDAISGTALSLAEAICSAKKDHFGDEQEPCIEMFGSRVG
HHHHHCCCCCEEEEECCCCCHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
NIFGEHEVSFVGKNERFVIRHEAFSRQTFSDGVLIILRKIMEERLPAGYYTSDVLYESLF
HHCCCCCEEEECCCCEEEEEEHHHCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHH
QEVVFD
HHHHCC
>Mature Secondary Structure
MKKSVGLIGNTGRMGGLLTEALRSHPRCLLGKGFSRRSQTLLKEVVLENDILIDFSAPEV
CCCCCCCCCCCCCHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHCCCEEEECCCCHH
TETLMDILLVTPKPVIIGTTGFSDNSVIRDKLSLLSEYVPVIFSPNMSLGAYVQRRLTAC
HHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCEEECCCCCHHHHHHHHHHHH
AAKLFDASYDVRILETHHRTKVDAISGTALSLAEAICSAKKDHFGDEQEPCIEMFGSRVG
HHHHHCCCCCEEEEECCCCCHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
NIFGEHEVSFVGKNERFVIRHEAFSRQTFSDGVLIILRKIMEERLPAGYYTSDVLYESLF
HHCCCCCEEEECCCCEEEEEEHHHCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHH
QEVVFD
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10684935