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The map label for this gene is asd

Identifier: 15835257

GI number: 15835257

Start: 768109

End: 769113

Strand: Reverse

Name: asd

Synonym: TC0642

Alternate gene names: 15835257

Gene position: 769113-768109 (Counterclockwise)

Preceding gene: 15835258

Following gene: 15835256

Centisome position: 71.68

GC content: 41.69

Gene sequence:

>1005_bases
GTGACGATGCGCATTGCAATTTTGGGTGCTACAGGCCTTGTCGGACAAAAGCTAATCGCTTTGTTACAAAGGCATAAGCA
GTGGGAGATTGCCGAATTGAGTGCTTCTCCTAAGAAGCACTCATTGCGTTATGAGTCTGCGTGTTTATGGCAAGAGCCTT
TAATGGCCATGCCAGAATCTGTTCAAGATCTTACAATTCGTTCTATTGAAGAGATTGAATCCGATATTGTTGTGTCTTGT
CTTCCTACATCCGTTGCTTTTTCTGCAGAAACCGCTTGTCTGTCCTCAGGGAAAATCGTGTTTTCCAACTCTGGCGCTTA
TCGAATGCATGAATCGGTGCCTATTTTAATTCCTGAGGTCAATAGTGATCACATATCCCTTCTAGATGATCAGCCTTTTT
TAGGGAAAATCGTTACCAATTCTAACTGCTGTGTCTCGGGTATTGCTTTAGCTCTTAGGCCACTGCTTCCATTTGATATC
GAACATGTGCATGTTGTTACTTTACAGTCTGCTAGTGGGGCTGGATATCCAGGAGTTTCTTCTTTGGATTTAATTGGGAA
TACGATTCCGCATATCCTAGGAGAGGAAGAAAAAATACATCAGGAGACTTTAAAAATTTTAGGCAGCCCCAGTTCTCCTG
CAGAATTTTCCATAACGGCATCTGTTCATCGTGTTCCCGTTATGTATGGGCATGTCATCTCGATGCATGTAATGTTTGCC
CAAGAAGTTTCTTTGGAAAAGATCTTTTGTTGTTACGAAAAATATTCTGATACGTATGTCCTTTATGATTCTCCTTGGCA
TCCTCAGGTGCAAAAAGATCTCCTTCACGATGATATGCGCTTACATATAGGTCCTATCTCTCATGGTGGAAGTGCGAAAA
CAATTAAAATGTGCGTTCTTCTTCATAATTTGGTTCGAGGCGCTGCAGGAGCCTTAATATCGAATATGAATTTTCTCCAG
GATAGGGTGAATCTTTTCTATCAAGAGGGGCTGGCACATGTTTAA

Upstream 100 bases:

>100_bases
AAGGAAAATTATGGAAGAAAGGTTGCCTGCAGGGTATTACACTTCTGATGTTTTGTATGAAAGTCTATTTCAGGAAGTTG
TTTTTGATTAAGAGCTAAAG

Downstream 100 bases:

>100_bases
AGAGAAAAAAGCGCCTCTTGTTTGCAAGTTCGGAGGAACGAGTGTAGGAACATCCTCCAGCATCCAACGTGTTTGCGAGA
TTATCCGAAAGGAAAAGCCC

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MTMRIAILGATGLVGQKLIALLQRHKQWEIAELSASPKKHSLRYESACLWQEPLMAMPESVQDLTIRSIEEIESDIVVSC
LPTSVAFSAETACLSSGKIVFSNSGAYRMHESVPILIPEVNSDHISLLDDQPFLGKIVTNSNCCVSGIALALRPLLPFDI
EHVHVVTLQSASGAGYPGVSSLDLIGNTIPHILGEEEKIHQETLKILGSPSSPAEFSITASVHRVPVMYGHVISMHVMFA
QEVSLEKIFCCYEKYSDTYVLYDSPWHPQVQKDLLHDDMRLHIGPISHGGSAKTIKMCVLLHNLVRGAAGALISNMNFLQ
DRVNLFYQEGLAHV

Sequences:

>Translated_334_residues
MTMRIAILGATGLVGQKLIALLQRHKQWEIAELSASPKKHSLRYESACLWQEPLMAMPESVQDLTIRSIEEIESDIVVSC
LPTSVAFSAETACLSSGKIVFSNSGAYRMHESVPILIPEVNSDHISLLDDQPFLGKIVTNSNCCVSGIALALRPLLPFDI
EHVHVVTLQSASGAGYPGVSSLDLIGNTIPHILGEEEKIHQETLKILGSPSSPAEFSITASVHRVPVMYGHVISMHVMFA
QEVSLEKIFCCYEKYSDTYVLYDSPWHPQVQKDLLHDDMRLHIGPISHGGSAKTIKMCVLLHNLVRGAAGALISNMNFLQ
DRVNLFYQEGLAHV
>Mature_333_residues
TMRIAILGATGLVGQKLIALLQRHKQWEIAELSASPKKHSLRYESACLWQEPLMAMPESVQDLTIRSIEEIESDIVVSCL
PTSVAFSAETACLSSGKIVFSNSGAYRMHESVPILIPEVNSDHISLLDDQPFLGKIVTNSNCCVSGIALALRPLLPFDIE
HVHVVTLQSASGAGYPGVSSLDLIGNTIPHILGEEEKIHQETLKILGSPSSPAEFSITASVHRVPVMYGHVISMHVMFAQ
EVSLEKIFCCYEKYSDTYVLYDSPWHPQVQKDLLHDDMRLHIGPISHGGSAKTIKMCVLLHNLVRGAAGALISNMNFLQD
RVNLFYQEGLAHV

Specific function: This enzyme catalyzes the second step in the common metabolic pathway to synthesize Thr and Met from Asp [H]

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320362, Length=346, Percent_Identity=32.0809248554913, Blast_Score=150, Evalue=4e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR005676
- InterPro:   IPR012080
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 36719; Mature: 36588

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMRIAILGATGLVGQKLIALLQRHKQWEIAELSASPKKHSLRYESACLWQEPLMAMPES
CEEEEEEEECCCHHHHHHHHHHHHCCCCCEEECCCCCCHHCCCHHHHHHHHHHHHHCCCC
VQDLTIRSIEEIESDIVVSCLPTSVAFSAETACLSSGKIVFSNSGAYRMHESVPILIPEV
HHHHHHHHHHHHHHCEEEEEECCCCCCCCHHHHHCCCCEEEECCCCEEEECCCCEEEECC
NSDHISLLDDQPFLGKIVTNSNCCVSGIALALRPLLPFDIEHVHVVTLQSASGAGYPGVS
CCCCEEEECCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCCCCC
SLDLIGNTIPHILGEEEKIHQETLKILGSPSSPAEFSITASVHRVPVMYGHVISMHVMFA
HHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHH
QEVSLEKIFCCYEKYSDTYVLYDSPWHPQVQKDLLHDDMRLHIGPISHGGSAKTIKMCVL
HHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHH
LHNLVRGAAGALISNMNFLQDRVNLFYQEGLAHV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TMRIAILGATGLVGQKLIALLQRHKQWEIAELSASPKKHSLRYESACLWQEPLMAMPES
EEEEEEEECCCHHHHHHHHHHHHCCCCCEEECCCCCCHHCCCHHHHHHHHHHHHHCCCC
VQDLTIRSIEEIESDIVVSCLPTSVAFSAETACLSSGKIVFSNSGAYRMHESVPILIPEV
HHHHHHHHHHHHHHCEEEEEECCCCCCCCHHHHHCCCCEEEECCCCEEEECCCCEEEECC
NSDHISLLDDQPFLGKIVTNSNCCVSGIALALRPLLPFDIEHVHVVTLQSASGAGYPGVS
CCCCEEEECCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCCCCC
SLDLIGNTIPHILGEEEKIHQETLKILGSPSSPAEFSITASVHRVPVMYGHVISMHVMFA
HHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHH
QEVSLEKIFCCYEKYSDTYVLYDSPWHPQVQKDLLHDDMRLHIGPISHGGSAKTIKMCVL
HHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHH
LHNLVRGAAGALISNMNFLQDRVNLFYQEGLAHV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]