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The map label for this gene is aphA [H]

Identifier: 158338978

GI number: 158338978

Start: 5957806

End: 5960241

Strand: Reverse

Name: aphA [H]

Synonym: AM1_5897

Alternate gene names: 158338978

Gene position: 5960241-5957806 (Counterclockwise)

Preceding gene: 158338980

Following gene: 158338977

Centisome position: 91.64

GC content: 41.75

Gene sequence:

>2436_bases
GTGACTCTCCTAAATATTTTTTTTCTCTCATATTATTTATTATTTGCTAATCTTTCAATTCAACTGGAGCAGTTCCCCTT
TACAATTATTCCAGATATAGCAATTGCTTTAGTATTTGGGAGTTCGGCTTTCCTAATAGGCTATATAGCCTATTGTCATC
AGTTCTTTAGCCATCCCAAGCTTTTTACTTTATTTATCGCGTTATTGGTTACTTTTAGCCTCATTTCGATTCTGGATATA
GCCTCTTTGTATATTCCTCTGGCTAGGGTACAAGGAGGTATAAAATTACTATCTGCTGCGATTGCAATATGGACGACCAG
GGAATTCATAGCAAATACTTTACAGACTTTATCTCCAAGTCATAGGACATCCTCTGCGAATAAAAGTCAACTCGTTAATC
AGGAAAATGAAGGAAGTCGGCAACAAGAGTCAGTATGGTGGGAAAACCAGCAGACTTTAAATAATATCTTTGAATATTCC
TTGATCGGCAAGGCGATTCTCACTCCTGATGAAGACTGGATCAGGGTTAATCCAGCCTTCTATAAAATCTTGGGGTATTC
AGAAGCAGATTTATTGCAGACCAATCTTAGAAATATTACCTATCCTGAGGATTTAGCCGCTGATCAACATTATCGTGACC
AATTATTATCTGGAGAGATTTCAGCCTGTCGTGTTGAAAAGCGATATTGCCACAAGCAAGGCCATATTGTTTGGGTCTCG
TTAAGTCTCTCTTTAGTCAGAGATTCCATGGGTCAGCCCTTATATCTAATTGCTGAAATCGATAATATCTCTGAACACAA
ACAGGTTGAAACAGATTTGAAATTGATCATTGGGCAGTTGAATCTTGCCATAAAAGATCGCTCTTCAGAATTAGATACAG
CTTACTCAAACTTGAAAAAATCTGCTGCTCAGTATCAAGATCTTTATGACAACGCTCCAGATATGTATCTATCGGTTGAT
GTTGATAGCACAAAGATTTTGCGTTGTAACCAAACATTAATGAAAGAGCTTGGATACAGCTATCCAGAGTTAGTTGGACG
CTCAGTGCTTGATCTATATCATCCTGATTCTCGATCAGATGCCAAAGAATCCTTCCAAACCTTTTTGGAAAAAGGTGAAG
TCAGGAATGGCAACCTATTGGTACAACGCAAAGATGGAACGACCTTGAATGTCAGTCTCAATGCTCAGGGGTTTCGAGAT
CAGCAAGGCAAGCTGAAGTACAGCCGTTCAAGCTGGAGAGACATCTCTGAGCGTAAACGCTTAGAGAACCAATTAAAGCA
AATGAATGCTGAGTTGGAAGAGCGGGTTAAAAATCGCACGTTGGCTTTACAAATTGCCGTTCAGTCCCTAAAAGAGAGTG
AATCCCGTTTGGAGTTGGCATTAGAGGCTTCTGGAGATGGGTGGTGGGATTGGAACATTCTCACCGATGAAACCAGCTGG
AGCACTCAGTTCTATCAAATACTGGGGTATGAATTGGAAGAATTGCCTTCCTCGTTTAAAACTTGGCAAAGCTGGACCCA
TCCAGATGACTTACTCAGAATAAAGACTCTGCTGAAGAAGCATTTACAAGACCCTTCCATCCCCTATGTGTTTGACTATC
GGGTCCGCACGAAATCCGAGCAATGGAAATGGATTTCGGCAATGGGAAAAGTCGTAGCCTGGAATGATCAGGGGGAACCC
CTTCGCATGGTGGGAATGCACCATGATATTAGTGAGCGCAAACAGGCAGAGCAAGAACTGCAAAGAATAAACAGTGAATT
AATTCGTTCCAACCAAGAGTTGGGCCATTTCGCCTATGTTGCCTCCCATGATTTGCAGGAACCCTTACGGAAAATTGGGA
GTTTTACCGATTTACTGGCCGATCGCTATCAGGGGCAACTCGACGAGACAGCAGATCGCTATATTCGCTACATCACCGAT
GGGGCAATGCGTATGCAGGGGTTAATAGATGATCTCCTGAACTATTCCCGCGTCGGACGAGCCGAACTGAAAGTTCAACC
CACAGCATTATCGTCCATCCTTGAAAAGGTAAAATCTGACTTAGAAAAGGTCATTGAAAAACGCCAGGTCGAGATTATTA
TAGATTCCTTGCCAACCGTTGCTGTCGATCCCGTGCTAATGGGGCAGGTATTCCAAAATTTGATTTCTAATGCCATTAAG
TATTGCCAAGCCGATCGTCCGAGGATTTATATTCGAGCCACTCAAGATCAAAAATTTTGGACTATTTCAGTTCAAGACAA
TGGAATTGGCATCAATCCACAGTTTACTGATCGGATATTTGTCATTTTTCAGCGATTACACCATCGAGAAGAATATTCGG
GCACCGGAATTGGTTTAGCCATTTGTAAAAAACTAGTTGAACGTCATGGGGGGCAAATCTGGGTAGATTCTGAAGAAGGT
AAAGGGGCGAACTTTTCCTTTACCCTACCTAAATGA

Upstream 100 bases:

>100_bases
CAAGATAAAACCTTTATGCACAAGTCAAAAATGGATTGATCTATTGAAAAAGTTTTCTATCTTGTCAGGTATTTGGATGA
TTTAACAGGAGATAATAAAT

Downstream 100 bases:

>100_bases
AATTTTTTATAAAGCCTTCAAAGAATCCTTAATTCGTTAAATGACCGTCAAAATCATCCATAATTAAATTTATCTGGCCA
ATAAATTATAATTCATGCGA

Product: PAS/PAC sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 811; Mature: 810

Protein sequence:

>811_residues
MTLLNIFFLSYYLLFANLSIQLEQFPFTIIPDIAIALVFGSSAFLIGYIAYCHQFFSHPKLFTLFIALLVTFSLISILDI
ASLYIPLARVQGGIKLLSAAIAIWTTREFIANTLQTLSPSHRTSSANKSQLVNQENEGSRQQESVWWENQQTLNNIFEYS
LIGKAILTPDEDWIRVNPAFYKILGYSEADLLQTNLRNITYPEDLAADQHYRDQLLSGEISACRVEKRYCHKQGHIVWVS
LSLSLVRDSMGQPLYLIAEIDNISEHKQVETDLKLIIGQLNLAIKDRSSELDTAYSNLKKSAAQYQDLYDNAPDMYLSVD
VDSTKILRCNQTLMKELGYSYPELVGRSVLDLYHPDSRSDAKESFQTFLEKGEVRNGNLLVQRKDGTTLNVSLNAQGFRD
QQGKLKYSRSSWRDISERKRLENQLKQMNAELEERVKNRTLALQIAVQSLKESESRLELALEASGDGWWDWNILTDETSW
STQFYQILGYELEELPSSFKTWQSWTHPDDLLRIKTLLKKHLQDPSIPYVFDYRVRTKSEQWKWISAMGKVVAWNDQGEP
LRMVGMHHDISERKQAEQELQRINSELIRSNQELGHFAYVASHDLQEPLRKIGSFTDLLADRYQGQLDETADRYIRYITD
GAMRMQGLIDDLLNYSRVGRAELKVQPTALSSILEKVKSDLEKVIEKRQVEIIIDSLPTVAVDPVLMGQVFQNLISNAIK
YCQADRPRIYIRATQDQKFWTISVQDNGIGINPQFTDRIFVIFQRLHHREEYSGTGIGLAICKKLVERHGGQIWVDSEEG
KGANFSFTLPK

Sequences:

>Translated_811_residues
MTLLNIFFLSYYLLFANLSIQLEQFPFTIIPDIAIALVFGSSAFLIGYIAYCHQFFSHPKLFTLFIALLVTFSLISILDI
ASLYIPLARVQGGIKLLSAAIAIWTTREFIANTLQTLSPSHRTSSANKSQLVNQENEGSRQQESVWWENQQTLNNIFEYS
LIGKAILTPDEDWIRVNPAFYKILGYSEADLLQTNLRNITYPEDLAADQHYRDQLLSGEISACRVEKRYCHKQGHIVWVS
LSLSLVRDSMGQPLYLIAEIDNISEHKQVETDLKLIIGQLNLAIKDRSSELDTAYSNLKKSAAQYQDLYDNAPDMYLSVD
VDSTKILRCNQTLMKELGYSYPELVGRSVLDLYHPDSRSDAKESFQTFLEKGEVRNGNLLVQRKDGTTLNVSLNAQGFRD
QQGKLKYSRSSWRDISERKRLENQLKQMNAELEERVKNRTLALQIAVQSLKESESRLELALEASGDGWWDWNILTDETSW
STQFYQILGYELEELPSSFKTWQSWTHPDDLLRIKTLLKKHLQDPSIPYVFDYRVRTKSEQWKWISAMGKVVAWNDQGEP
LRMVGMHHDISERKQAEQELQRINSELIRSNQELGHFAYVASHDLQEPLRKIGSFTDLLADRYQGQLDETADRYIRYITD
GAMRMQGLIDDLLNYSRVGRAELKVQPTALSSILEKVKSDLEKVIEKRQVEIIIDSLPTVAVDPVLMGQVFQNLISNAIK
YCQADRPRIYIRATQDQKFWTISVQDNGIGINPQFTDRIFVIFQRLHHREEYSGTGIGLAICKKLVERHGGQIWVDSEEG
KGANFSFTLPK
>Mature_810_residues
TLLNIFFLSYYLLFANLSIQLEQFPFTIIPDIAIALVFGSSAFLIGYIAYCHQFFSHPKLFTLFIALLVTFSLISILDIA
SLYIPLARVQGGIKLLSAAIAIWTTREFIANTLQTLSPSHRTSSANKSQLVNQENEGSRQQESVWWENQQTLNNIFEYSL
IGKAILTPDEDWIRVNPAFYKILGYSEADLLQTNLRNITYPEDLAADQHYRDQLLSGEISACRVEKRYCHKQGHIVWVSL
SLSLVRDSMGQPLYLIAEIDNISEHKQVETDLKLIIGQLNLAIKDRSSELDTAYSNLKKSAAQYQDLYDNAPDMYLSVDV
DSTKILRCNQTLMKELGYSYPELVGRSVLDLYHPDSRSDAKESFQTFLEKGEVRNGNLLVQRKDGTTLNVSLNAQGFRDQ
QGKLKYSRSSWRDISERKRLENQLKQMNAELEERVKNRTLALQIAVQSLKESESRLELALEASGDGWWDWNILTDETSWS
TQFYQILGYELEELPSSFKTWQSWTHPDDLLRIKTLLKKHLQDPSIPYVFDYRVRTKSEQWKWISAMGKVVAWNDQGEPL
RMVGMHHDISERKQAEQELQRINSELIRSNQELGHFAYVASHDLQEPLRKIGSFTDLLADRYQGQLDETADRYIRYITDG
AMRMQGLIDDLLNYSRVGRAELKVQPTALSSILEKVKSDLEKVIEKRQVEIIIDSLPTVAVDPVLMGQVFQNLISNAIKY
CQADRPRIYIRATQDQKFWTISVQDNGIGINPQFTDRIFVIFQRLHHREEYSGTGIGLAICKKLVERHGGQIWVDSEEGK
GANFSFTLPK

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=250, Percent_Identity=30, Blast_Score=121, Evalue=2e-28,
Organism=Escherichia coli, GI48994928, Length=300, Percent_Identity=28, Blast_Score=111, Evalue=2e-25,
Organism=Escherichia coli, GI1788381, Length=226, Percent_Identity=31.4159292035398, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI87081816, Length=259, Percent_Identity=27.7992277992278, Blast_Score=92, Evalue=2e-19,
Organism=Escherichia coli, GI1790436, Length=220, Percent_Identity=29.5454545454545, Blast_Score=90, Evalue=6e-19,
Organism=Escherichia coli, GI1789149, Length=245, Percent_Identity=29.3877551020408, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1788549, Length=372, Percent_Identity=25.5376344086022, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1786600, Length=268, Percent_Identity=26.1194029850746, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1788713, Length=251, Percent_Identity=21.5139442231076, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI87082128, Length=213, Percent_Identity=27.6995305164319, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1787894, Length=215, Percent_Identity=28.8372093023256, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1786912, Length=214, Percent_Identity=30.3738317757009, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1788279, Length=270, Percent_Identity=24.4444444444444, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1790861, Length=243, Percent_Identity=25.9259259259259, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1789808, Length=215, Percent_Identity=26.9767441860465, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1786783, Length=222, Percent_Identity=27.4774774774775, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1790300, Length=245, Percent_Identity=27.3469387755102, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI1790346, Length=205, Percent_Identity=28.2926829268293, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI1788393, Length=250, Percent_Identity=25.2, Blast_Score=63, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR013654
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF00512 HisKA; PF08446 PAS_2; PF00360 Phytochrome [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 93193; Mature: 93062

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLLNIFFLSYYLLFANLSIQLEQFPFTIIPDIAIALVFGSSAFLIGYIAYCHQFFSHPK
CHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCH
LFTLFIALLVTFSLISILDIASLYIPLARVQGGIKLLSAAIAIWTTREFIANTLQTLSPS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
HRTSSANKSQLVNQENEGSRQQESVWWENQQTLNNIFEYSLIGKAILTPDEDWIRVNPAF
CCCCCCCHHHHCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHCCEEECCCCCCEEECHHH
YKILGYSEADLLQTNLRNITYPEDLAADQHYRDQLLSGEISACRVEKRYCHKQGHIVWVS
HHHCCCCHHHHHHHHHCCCCCCHHHCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEE
LSLSLVRDSMGQPLYLIAEIDNISEHKQVETDLKLIIGQLNLAIKDRSSELDTAYSNLKK
EHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCEEEECCCCHHHHHHHHHHH
SAAQYQDLYDNAPDMYLSVDVDSTKILRCNQTLMKELGYSYPELVGRSVLDLYHPDSRSD
HHHHHHHHHCCCCCEEEEEECCCCEEEEHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCH
AKESFQTFLEKGEVRNGNLLVQRKDGTTLNVSLNAQGFRDQQGKLKYSRSSWRDISERKR
HHHHHHHHHHCCCCCCCCEEEEECCCCEEEEEECCCCCCCCCCCEEECHHHHHHHHHHHH
LENQLKQMNAELEERVKNRTLALQIAVQSLKESESRLELALEASGDGWWDWNILTDETSW
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHEEEEEEECCCCEEEEEEEECCCCC
STQFYQILGYELEELPSSFKTWQSWTHPDDLLRIKTLLKKHLQDPSIPYVFDYRVRTKSE
HHHHHHHHCCCHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCC
QWKWISAMGKVVAWNDQGEPLRMVGMHHDISERKQAEQELQRINSELIRSNQELGHFAYV
HHHHHHHCCCEEEECCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
ASHDLQEPLRKIGSFTDLLADRYQGQLDETADRYIRYITDGAMRMQGLIDDLLNYSRVGR
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
AELKVQPTALSSILEKVKSDLEKVIEKRQVEIIIDSLPTVAVDPVLMGQVFQNLISNAIK
CCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHH
YCQADRPRIYIRATQDQKFWTISVQDNGIGINPQFTDRIFVIFQRLHHREEYSGTGIGLA
HHCCCCCEEEEEEECCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHH
ICKKLVERHGGQIWVDSEEGKGANFSFTLPK
HHHHHHHHCCCEEEEECCCCCCCCEEEECCC
>Mature Secondary Structure 
TLLNIFFLSYYLLFANLSIQLEQFPFTIIPDIAIALVFGSSAFLIGYIAYCHQFFSHPK
HHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCH
LFTLFIALLVTFSLISILDIASLYIPLARVQGGIKLLSAAIAIWTTREFIANTLQTLSPS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
HRTSSANKSQLVNQENEGSRQQESVWWENQQTLNNIFEYSLIGKAILTPDEDWIRVNPAF
CCCCCCCHHHHCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHCCEEECCCCCCEEECHHH
YKILGYSEADLLQTNLRNITYPEDLAADQHYRDQLLSGEISACRVEKRYCHKQGHIVWVS
HHHCCCCHHHHHHHHHCCCCCCHHHCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEE
LSLSLVRDSMGQPLYLIAEIDNISEHKQVETDLKLIIGQLNLAIKDRSSELDTAYSNLKK
EHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCEEEECCCCHHHHHHHHHHH
SAAQYQDLYDNAPDMYLSVDVDSTKILRCNQTLMKELGYSYPELVGRSVLDLYHPDSRSD
HHHHHHHHHCCCCCEEEEEECCCCEEEEHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCH
AKESFQTFLEKGEVRNGNLLVQRKDGTTLNVSLNAQGFRDQQGKLKYSRSSWRDISERKR
HHHHHHHHHHCCCCCCCCEEEEECCCCEEEEEECCCCCCCCCCCEEECHHHHHHHHHHHH
LENQLKQMNAELEERVKNRTLALQIAVQSLKESESRLELALEASGDGWWDWNILTDETSW
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHEEEEEEECCCCEEEEEEEECCCCC
STQFYQILGYELEELPSSFKTWQSWTHPDDLLRIKTLLKKHLQDPSIPYVFDYRVRTKSE
HHHHHHHHCCCHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCC
QWKWISAMGKVVAWNDQGEPLRMVGMHHDISERKQAEQELQRINSELIRSNQELGHFAYV
HHHHHHHCCCEEEECCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
ASHDLQEPLRKIGSFTDLLADRYQGQLDETADRYIRYITDGAMRMQGLIDDLLNYSRVGR
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
AELKVQPTALSSILEKVKSDLEKVIEKRQVEIIIDSLPTVAVDPVLMGQVFQNLISNAIK
CCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHH
YCQADRPRIYIRATQDQKFWTISVQDNGIGINPQFTDRIFVIFQRLHHREEYSGTGIGLA
HHCCCCCEEEEEEECCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHH
ICKKLVERHGGQIWVDSEEGKGANFSFTLPK
HHHHHHHHCCCEEEEECCCCCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]