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The map label for this gene is yciR [C]

Identifier: 158338195

GI number: 158338195

Start: 5140748

End: 5143015

Strand: Reverse

Name: yciR [C]

Synonym: AM1_5088

Alternate gene names: 158338195

Gene position: 5143015-5140748 (Counterclockwise)

Preceding gene: 158338196

Following gene: 158338194

Centisome position: 79.08

GC content: 49.65

Gene sequence:

>2268_bases
GTGACGTTCCCTCCGCTGTCCGAAATCGTGAAAAGCGACCAACAGTCCAAATTAGATCATCTGTCTGCTGCTTGCCCTGC
GGTTATGTATAGCAGCTGTCCAGGTGCCTATGAATTAACGGCTGTTTCTAAGAGCGTTACCTCCCTGTTTGGCTATACAG
ATCAGGATTTGCTAGCAGAGCCAACCCGCTGGCTCTCCCTGATCCATCCTGACGATCGGTCTCTGGCCTTAGAAACCCTT
AGCCAAGGCACATTAGATGTTTGGCAGGAGTGTGAGTACCGTTTTTTTCATAAACAGTTAGGGTATCGCTGGGTTCAGAA
TATTTTTCAGCTCGTGTCGAAACCCAACGGACCCGGACTAGAACTGATCGGTTGTTGGCTGGATCGCACGGAACACCTCC
AGCATCGACTAGCTCAGCAACAGCGGGATAACCTACTGACCGCCGTGGCAGAAGCCAGTCAATATCTGCTCACGGGTTCC
CATTTCAATACAGCTGTCACCAAGGCCCTGGCAGTAGTCGGCAATGCCGCCCAGATCGATCGCCTCTATGTTTGTGAACT
CCATACATCGACCGCTGGCGTGCTTACCCCCCAGCTGCGCTATGCCTGGGTAAAAAAGACCGAGTCAGCGTCCAGTTTAC
ATTTGCCTTGGACCGTTCCCTCCGATGTGATTGGTCAACGACGGTGGTACCAGTCCTTGGTTCGTCGTCTACCGTTTTCC
CAGCTAACCCGAGATTTTCATGAGATTGAGCGATCGCATCTAAAACGAGCTGACATTTGCTCGGTGTTTCTACTCCCCAT
CATTATCGAGGACCAGCTCTGGGGATTTATGAGCTTTGAAAATCGTCATATTGAGCGCCAATGGTCTACGCCCGATATTT
CCCTATTGCAAACCTTGGTGGCAAGTCTTAGTGGAGCCTTAAAGCATCACCAAAAAGAGACAGAACTGCTCCATCATGCC
TTCCACGATCCCCTAACGGATCTACCCAATCGCGCCCTATTTATTAATCGGCTCGAACAATCCCTCAAACAGCTGCAGCG
CTATCCCGATTATCTGTTTGCAGTACTGTTCTTGGATTTAGATCGGTTCAAAATCATTAACGACAGCATGGGACATGGAG
TGGGCGATCAGTTGCTGATGGGCATTGCTGAACGGCTGCTCTCTTCTTTGCGTCCCGGTGATACGGCCTCTCGCTTAGGT
GGAGATGAATTTGTTATTTTGCTCAATGGCCTCCAAAACCAAGAAGATGCGACCTCCACAGCAGAGCGCCTGCGACAACA
ATTGACCCTACCCTTTAATTTAGGGGTACATGAAATTTTCATTGATGTCAGCATTGGCATTACCCTCAGCAACTTTGGCT
ACCACGATGCTGAACAGGTGCTTCAGGATGCGGATGTGGCCATGTACCAGGCTAAGTCCGCCGGCAAGGGCTGCCATAAG
GTCTTTAATACGGGCATGCAGTCCCAGACAATGGCGCGATCTCAGTTGGAAACGGAAATGCGGCGAGCCATTGAACGCCA
AGCCTTTGAAATTTACTACCAGCCTATTGTTTGTCTAAAAACTGGAGCCATTGACGCCTTCGAGGCGTTGATCCGCTGGT
ACGACAGCAACCATCAACCCATCGCCGCCTCGGATCTGATTGGCATTGCTGAGGAGTCCGGCATGATCCAGGACTTAGGA
TTATCGGTCTTGCAGCAGGCCTGCAATCAACTCCGTCAATGGCAGCGTCTTCCAGATTATGAGACCCTGCGCATTAGCGT
TAATTTATCGGCTAAACAGCTGTTTCATAGCGATTTGGTCACTAAGGTGGCGGATATCATAGCTGCCTCTCGCATCGACC
CCACCCATCTGAAACTAGAGCTAACGGAAAGCACGATTATTCGCAATGATCAGACGACGATAAGTTTACTGAAACAATTG
CGGGAGCTGGGGCTAGAACTCTATCTGGATGATTTTGGAGCGGGCTATTCTTCTCTCAGCTACCTGTATAGCCTACCGAT
TAATGCCCTAAAAATCGATCAAACCTTTGTCCAACGAATCGATATGGGAGCAGAGGGGCAAGCCATTATCCGTTCGATTC
TCTTATTAGCCAATAATTTGGATCTACAGGTAGTAGCAGAAGGGGTTGAAAATAAAATCCAGCTTAATTACCTCAATTCT
CTCAACTGTACCCACGGCCAAGGCTTTTTGTTTGCCCCACCCCTAACGGCGAGGGGCGCGACATCCTTGTTGCGATCGCA
AGATCGATTCGAGTACCAATCTGCTTAA

Upstream 100 bases:

>100_bases
GGAAGCAGGTTTATTCAGCCAGTATTCAGAAATATACGTGAATTTACGCCATTTCAATTGGTGAAAGTCATGTTTTACCT
GTGCTTGGAGTAATTTTGGT

Downstream 100 bases:

>100_bases
AATCCATTTCAGTCTTGCCCCTGAGTCTAAATATATGGCATAGGGCAATTTTCAGGACTTTTACCTTGCTGTAGCACACA
AATATTCCATTGCTCAGTAC

Product: diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 755; Mature: 754

Protein sequence:

>755_residues
MTFPPLSEIVKSDQQSKLDHLSAACPAVMYSSCPGAYELTAVSKSVTSLFGYTDQDLLAEPTRWLSLIHPDDRSLALETL
SQGTLDVWQECEYRFFHKQLGYRWVQNIFQLVSKPNGPGLELIGCWLDRTEHLQHRLAQQQRDNLLTAVAEASQYLLTGS
HFNTAVTKALAVVGNAAQIDRLYVCELHTSTAGVLTPQLRYAWVKKTESASSLHLPWTVPSDVIGQRRWYQSLVRRLPFS
QLTRDFHEIERSHLKRADICSVFLLPIIIEDQLWGFMSFENRHIERQWSTPDISLLQTLVASLSGALKHHQKETELLHHA
FHDPLTDLPNRALFINRLEQSLKQLQRYPDYLFAVLFLDLDRFKIINDSMGHGVGDQLLMGIAERLLSSLRPGDTASRLG
GDEFVILLNGLQNQEDATSTAERLRQQLTLPFNLGVHEIFIDVSIGITLSNFGYHDAEQVLQDADVAMYQAKSAGKGCHK
VFNTGMQSQTMARSQLETEMRRAIERQAFEIYYQPIVCLKTGAIDAFEALIRWYDSNHQPIAASDLIGIAEESGMIQDLG
LSVLQQACNQLRQWQRLPDYETLRISVNLSAKQLFHSDLVTKVADIIAASRIDPTHLKLELTESTIIRNDQTTISLLKQL
RELGLELYLDDFGAGYSSLSYLYSLPINALKIDQTFVQRIDMGAEGQAIIRSILLLANNLDLQVVAEGVENKIQLNYLNS
LNCTHGQGFLFAPPLTARGATSLLRSQDRFEYQSA

Sequences:

>Translated_755_residues
MTFPPLSEIVKSDQQSKLDHLSAACPAVMYSSCPGAYELTAVSKSVTSLFGYTDQDLLAEPTRWLSLIHPDDRSLALETL
SQGTLDVWQECEYRFFHKQLGYRWVQNIFQLVSKPNGPGLELIGCWLDRTEHLQHRLAQQQRDNLLTAVAEASQYLLTGS
HFNTAVTKALAVVGNAAQIDRLYVCELHTSTAGVLTPQLRYAWVKKTESASSLHLPWTVPSDVIGQRRWYQSLVRRLPFS
QLTRDFHEIERSHLKRADICSVFLLPIIIEDQLWGFMSFENRHIERQWSTPDISLLQTLVASLSGALKHHQKETELLHHA
FHDPLTDLPNRALFINRLEQSLKQLQRYPDYLFAVLFLDLDRFKIINDSMGHGVGDQLLMGIAERLLSSLRPGDTASRLG
GDEFVILLNGLQNQEDATSTAERLRQQLTLPFNLGVHEIFIDVSIGITLSNFGYHDAEQVLQDADVAMYQAKSAGKGCHK
VFNTGMQSQTMARSQLETEMRRAIERQAFEIYYQPIVCLKTGAIDAFEALIRWYDSNHQPIAASDLIGIAEESGMIQDLG
LSVLQQACNQLRQWQRLPDYETLRISVNLSAKQLFHSDLVTKVADIIAASRIDPTHLKLELTESTIIRNDQTTISLLKQL
RELGLELYLDDFGAGYSSLSYLYSLPINALKIDQTFVQRIDMGAEGQAIIRSILLLANNLDLQVVAEGVENKIQLNYLNS
LNCTHGQGFLFAPPLTARGATSLLRSQDRFEYQSA
>Mature_754_residues
TFPPLSEIVKSDQQSKLDHLSAACPAVMYSSCPGAYELTAVSKSVTSLFGYTDQDLLAEPTRWLSLIHPDDRSLALETLS
QGTLDVWQECEYRFFHKQLGYRWVQNIFQLVSKPNGPGLELIGCWLDRTEHLQHRLAQQQRDNLLTAVAEASQYLLTGSH
FNTAVTKALAVVGNAAQIDRLYVCELHTSTAGVLTPQLRYAWVKKTESASSLHLPWTVPSDVIGQRRWYQSLVRRLPFSQ
LTRDFHEIERSHLKRADICSVFLLPIIIEDQLWGFMSFENRHIERQWSTPDISLLQTLVASLSGALKHHQKETELLHHAF
HDPLTDLPNRALFINRLEQSLKQLQRYPDYLFAVLFLDLDRFKIINDSMGHGVGDQLLMGIAERLLSSLRPGDTASRLGG
DEFVILLNGLQNQEDATSTAERLRQQLTLPFNLGVHEIFIDVSIGITLSNFGYHDAEQVLQDADVAMYQAKSAGKGCHKV
FNTGMQSQTMARSQLETEMRRAIERQAFEIYYQPIVCLKTGAIDAFEALIRWYDSNHQPIAASDLIGIAEESGMIQDLGL
SVLQQACNQLRQWQRLPDYETLRISVNLSAKQLFHSDLVTKVADIIAASRIDPTHLKLELTESTIIRNDQTTISLLKQLR
ELGLELYLDDFGAGYSSLSYLYSLPINALKIDQTFVQRIDMGAEGQAIIRSILLLANNLDLQVVAEGVENKIQLNYLNSL
NCTHGQGFLFAPPLTARGATSLLRSQDRFEYQSA

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=439, Percent_Identity=35.5353075170843, Blast_Score=269, Evalue=6e-73,
Organism=Escherichia coli, GI87081921, Length=417, Percent_Identity=33.5731414868106, Blast_Score=211, Evalue=1e-55,
Organism=Escherichia coli, GI226510982, Length=432, Percent_Identity=30.5555555555556, Blast_Score=190, Evalue=4e-49,
Organism=Escherichia coli, GI87081845, Length=256, Percent_Identity=34.375, Blast_Score=141, Evalue=2e-34,
Organism=Escherichia coli, GI87081743, Length=236, Percent_Identity=33.4745762711864, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI1790496, Length=239, Percent_Identity=33.4728033472803, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI1786507, Length=237, Percent_Identity=29.535864978903, Blast_Score=117, Evalue=4e-27,
Organism=Escherichia coli, GI1787055, Length=237, Percent_Identity=32.0675105485232, Blast_Score=116, Evalue=4e-27,
Organism=Escherichia coli, GI1788849, Length=423, Percent_Identity=23.4042553191489, Blast_Score=103, Evalue=5e-23,
Organism=Escherichia coli, GI1788381, Length=204, Percent_Identity=38.7254901960784, Blast_Score=102, Evalue=8e-23,
Organism=Escherichia coli, GI87081977, Length=197, Percent_Identity=34.010152284264, Blast_Score=102, Evalue=9e-23,
Organism=Escherichia coli, GI1788956, Length=169, Percent_Identity=39.0532544378698, Blast_Score=99, Evalue=8e-22,
Organism=Escherichia coli, GI1788502, Length=238, Percent_Identity=26.890756302521, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI87081980, Length=249, Percent_Identity=28.1124497991968, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1787262, Length=161, Percent_Identity=33.5403726708075, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI87082007, Length=173, Percent_Identity=38.150289017341, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI87082096, Length=423, Percent_Identity=23.8770685579196, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1789650, Length=451, Percent_Identity=21.9512195121951, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI145693134, Length=162, Percent_Identity=34.5679012345679, Blast_Score=87, Evalue=5e-18,
Organism=Escherichia coli, GI1786584, Length=207, Percent_Identity=28.0193236714976, Blast_Score=83, Evalue=7e-17,
Organism=Escherichia coli, GI1788085, Length=161, Percent_Identity=34.7826086956522, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI87081881, Length=165, Percent_Identity=36.3636363636364, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1787816, Length=197, Percent_Identity=30.4568527918782, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1787802, Length=190, Percent_Identity=28.4210526315789, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI1787410, Length=149, Percent_Identity=30.8724832214765, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1787056, Length=177, Percent_Identity=29.3785310734463, Blast_Score=66, Evalue=8e-12,
Organism=Escherichia coli, GI87081974, Length=87, Percent_Identity=41.3793103448276, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 85213; Mature: 85082

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: PS50112 PAS ; PS00445 FGGY_KINASES_2 ; PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFPPLSEIVKSDQQSKLDHLSAACPAVMYSSCPGAYELTAVSKSVTSLFGYTDQDLLAE
CCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHCCCCHHHHHC
PTRWLSLIHPDDRSLALETLSQGTLDVWQECEYRFFHKQLGYRWVQNIFQLVSKPNGPGL
CHHHHEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
ELIGCWLDRTEHLQHRLAQQQRDNLLTAVAEASQYLLTGSHFNTAVTKALAVVGNAAQID
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHCCHHHHC
RLYVCELHTSTAGVLTPQLRYAWVKKTESASSLHLPWTVPSDVIGQRRWYQSLVRRLPFS
EEEEEEEECCCCCCCCHHHHHHHHHCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHCCHH
QLTRDFHEIERSHLKRADICSVFLLPIIIEDQLWGFMSFENRHIERQWSTPDISLLQTLV
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHH
ASLSGALKHHQKETELLHHAFHDPLTDLPNRALFINRLEQSLKQLQRYPDYLFAVLFLDL
HHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DRFKIINDSMGHGVGDQLLMGIAERLLSSLRPGDTASRLGGDEFVILLNGLQNQEDATST
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHCCCCEEEEEECCCCCCCHHHHH
AERLRQQLTLPFNLGVHEIFIDVSIGITLSNFGYHDAEQVLQDADVAMYQAKSAGKGCHK
HHHHHHHCCCCCCCCCEEEEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCHHHHH
VFNTGMQSQTMARSQLETEMRRAIERQAFEIYYQPIVCLKTGAIDAFEALIRWYDSNHQP
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHCCCCCC
IAASDLIGIAEESGMIQDLGLSVLQQACNQLRQWQRLPDYETLRISVNLSAKQLFHSDLV
CHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECHHHHHHHHHHH
TKVADIIAASRIDPTHLKLELTESTIIRNDQTTISLLKQLRELGLELYLDDFGAGYSSLS
HHHHHHHHHCCCCCCEEEEEEEHHHHCCCCHHHHHHHHHHHHCCCEEEEHHHCCCHHHHH
YLYSLPINALKIDQTFVQRIDMGAEGQAIIRSILLLANNLDLQVVAEGVENKIQLNYLNS
HHHHCCCCCEEHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCEEEEEECC
LNCTHGQGFLFAPPLTARGATSLLRSQDRFEYQSA
CCCCCCCCEEECCCCCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TFPPLSEIVKSDQQSKLDHLSAACPAVMYSSCPGAYELTAVSKSVTSLFGYTDQDLLAE
CCCCHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHCCCCHHHHHC
PTRWLSLIHPDDRSLALETLSQGTLDVWQECEYRFFHKQLGYRWVQNIFQLVSKPNGPGL
CHHHHEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
ELIGCWLDRTEHLQHRLAQQQRDNLLTAVAEASQYLLTGSHFNTAVTKALAVVGNAAQID
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHCCHHHHC
RLYVCELHTSTAGVLTPQLRYAWVKKTESASSLHLPWTVPSDVIGQRRWYQSLVRRLPFS
EEEEEEEECCCCCCCCHHHHHHHHHCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHCCHH
QLTRDFHEIERSHLKRADICSVFLLPIIIEDQLWGFMSFENRHIERQWSTPDISLLQTLV
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHH
ASLSGALKHHQKETELLHHAFHDPLTDLPNRALFINRLEQSLKQLQRYPDYLFAVLFLDL
HHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DRFKIINDSMGHGVGDQLLMGIAERLLSSLRPGDTASRLGGDEFVILLNGLQNQEDATST
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHCCCCEEEEEECCCCCCCHHHHH
AERLRQQLTLPFNLGVHEIFIDVSIGITLSNFGYHDAEQVLQDADVAMYQAKSAGKGCHK
HHHHHHHCCCCCCCCCEEEEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCHHHHH
VFNTGMQSQTMARSQLETEMRRAIERQAFEIYYQPIVCLKTGAIDAFEALIRWYDSNHQP
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHCCCCCC
IAASDLIGIAEESGMIQDLGLSVLQQACNQLRQWQRLPDYETLRISVNLSAKQLFHSDLV
CHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECHHHHHHHHHHH
TKVADIIAASRIDPTHLKLELTESTIIRNDQTTISLLKQLRELGLELYLDDFGAGYSSLS
HHHHHHHHHCCCCCCEEEEEEEHHHHCCCCHHHHHHHHHHHHCCCEEEEHHHCCCHHHHH
YLYSLPINALKIDQTFVQRIDMGAEGQAIIRSILLLANNLDLQVVAEGVENKIQLNYLNS
HHHHCCCCCEEHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCEEEEEECC
LNCTHGQGFLFAPPLTARGATSLLRSQDRFEYQSA
CCCCCCCCEEECCCCCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]