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The map label for this gene is sds [H]

Identifier: 158338022

GI number: 158338022

Start: 4956342

End: 4957313

Strand: Reverse

Name: sds [H]

Synonym: AM1_4909

Alternate gene names: 158338022

Gene position: 4957313-4956342 (Counterclockwise)

Preceding gene: 158338023

Following gene: 158338021

Centisome position: 76.22

GC content: 49.59

Gene sequence:

>972_bases
ATGACCTCAGTAACATCCCTTTTTGATCCAGTTGAAGCCGATTTAGCCATATTGGTGGATAACCTCAAAGACCTGGTACG
CGCCCAACATCCAGTTCTTTTCGCTGCGGCTGAACATCTGTTTCAAGCTGGAGGGAAGCGGATGCGTCCAGCCATTGTGC
TCCTCCTCTCTAGAGCGTTACTCCCGGATCAAGACCTCACCCCTCGACATCGACGGTTGGCAGAGATCACCGAGATGATT
CATACCGCCAGCCTGCTCCATGATGATGTGGTAGACGATTCAGGGGTTCGTCGTGGAGTACCGTCGGTCCACAGCCTGTT
TGGCAACCGCATAGCTATTCAAGCAGGGGATTTTCTGTTTGCCCAAGCATCTTGGTATTTGGCGAACTTAGACAACCTAG
AGGTGGTCAAGCTCCTGTCTGAAGTGATTAAAGATTTCGCGGAAGGAGAAATCCAGCAGGGTATCAACTGCTTTGACACA
TCCTTGACCCTCGAAGCCTATCTGGAGAAGTCCTACTATAAGACCGCTTCCTTAATGGCAAACAGCGCCAAGGCTGCGGG
AGTCTTGAGCGGCACCTCCTTGCAGGTCAACCAAGATTTATATGCCTATGGTCGCTGTGTCGGCTTAGCCTTCCAAATTG
TCGATGATATTTTGGACTTCACCGGGTCGACAAATGCCCTAGGCAAACCCGCTTGTTCGGATCTACGTAGCGGGAATTTA
ACGGCCCCGGTCCTGTTTGCAATTGCAGAAAAGCCTTACCTCAAAGTCTTGATTGATCGGCATTTGGAAGAGGAAGAAGA
CCTAGACGAAGCCATTGCCCTTGTGAATGATAGTCAAGGAATTCCTAAATCTCGGGCCCTGGCTGAACAATTTGCCCATC
AGGCTGTTCATCATTTGGACTTCCTTCCCGCTTCTGATTCCCGACAAGCTCTAATTGATTTAACGGAATATATCCTCAAA
CGACTCTACTGA

Upstream 100 bases:

>100_bases
GGGTTATAAACCCTCTTGTAAACGAAGAGAGTTACAATGTGATAAGCATATGTAAAATTTTGTAATCTTTATTTCATAAC
CGTCTGAGATAAGCAAATCA

Downstream 100 bases:

>100_bases
GGAGTACCCTAGTGATCTAGAAGATTGATTGTCCATTTTACGAGAGAACCCCTATGACCTCAGAGGATCGGCCCACACCT
GAGGCAGCCCCCATTCCCCC

Product: trans-octaprenyltranstransferase

Products: trans-polyisoprenyln-PP; pyrophosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 323; Mature: 322

Protein sequence:

>323_residues
MTSVTSLFDPVEADLAILVDNLKDLVRAQHPVLFAAAEHLFQAGGKRMRPAIVLLLSRALLPDQDLTPRHRRLAEITEMI
HTASLLHDDVVDDSGVRRGVPSVHSLFGNRIAIQAGDFLFAQASWYLANLDNLEVVKLLSEVIKDFAEGEIQQGINCFDT
SLTLEAYLEKSYYKTASLMANSAKAAGVLSGTSLQVNQDLYAYGRCVGLAFQIVDDILDFTGSTNALGKPACSDLRSGNL
TAPVLFAIAEKPYLKVLIDRHLEEEEDLDEAIALVNDSQGIPKSRALAEQFAHQAVHHLDFLPASDSRQALIDLTEYILK
RLY

Sequences:

>Translated_323_residues
MTSVTSLFDPVEADLAILVDNLKDLVRAQHPVLFAAAEHLFQAGGKRMRPAIVLLLSRALLPDQDLTPRHRRLAEITEMI
HTASLLHDDVVDDSGVRRGVPSVHSLFGNRIAIQAGDFLFAQASWYLANLDNLEVVKLLSEVIKDFAEGEIQQGINCFDT
SLTLEAYLEKSYYKTASLMANSAKAAGVLSGTSLQVNQDLYAYGRCVGLAFQIVDDILDFTGSTNALGKPACSDLRSGNL
TAPVLFAIAEKPYLKVLIDRHLEEEEDLDEAIALVNDSQGIPKSRALAEQFAHQAVHHLDFLPASDSRQALIDLTEYILK
RLY
>Mature_322_residues
TSVTSLFDPVEADLAILVDNLKDLVRAQHPVLFAAAEHLFQAGGKRMRPAIVLLLSRALLPDQDLTPRHRRLAEITEMIH
TASLLHDDVVDDSGVRRGVPSVHSLFGNRIAIQAGDFLFAQASWYLANLDNLEVVKLLSEVIKDFAEGEIQQGINCFDTS
LTLEAYLEKSYYKTASLMANSAKAAGVLSGTSLQVNQDLYAYGRCVGLAFQIVDDILDFTGSTNALGKPACSDLRSGNLT
APVLFAIAEKPYLKVLIDRHLEEEEDLDEAIALVNDSQGIPKSRALAEQFAHQAVHHLDFLPASDSRQALIDLTEYILKR
LY

Specific function: Possible role in synthesis of the nonaprenyl side chain of plastoquinone or in synthesis of other prenyl chains such as undekaprenyl pyrophosphate [H]

COG id: COG0142

COG function: function code H; Geranylgeranyl pyrophosphate synthase

Gene ontology:
GO:0008299: Trans-octaprenyltranstransferase
GO:0015979: Trans-octaprenyltranstransferase
GO:0016740: Trans-octaprenyltranstransferase
GO:0016765: Trans-octaprenyltranstransferase

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FPP/GGPP synthase family [H]

Homologues:

Organism=Homo sapiens, GI50659086, Length=323, Percent_Identity=38.390092879257, Blast_Score=216, Evalue=2e-56,
Organism=Homo sapiens, GI169808399, Length=335, Percent_Identity=25.9701492537313, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI4758430, Length=226, Percent_Identity=29.2035398230088, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI83700220, Length=226, Percent_Identity=29.2035398230088, Blast_Score=89, Evalue=5e-18,
Organism=Escherichia coli, GI1789578, Length=287, Percent_Identity=35.191637630662, Blast_Score=175, Evalue=4e-45,
Organism=Escherichia coli, GI1786623, Length=225, Percent_Identity=32, Blast_Score=69, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17505681, Length=325, Percent_Identity=33.5384615384615, Blast_Score=189, Evalue=1e-48,
Organism=Saccharomyces cerevisiae, GI6319475, Length=299, Percent_Identity=41.8060200668896, Blast_Score=209, Evalue=5e-55,
Organism=Saccharomyces cerevisiae, GI6325188, Length=250, Percent_Identity=23.2, Blast_Score=69, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24651612, Length=316, Percent_Identity=35.4430379746835, Blast_Score=202, Evalue=3e-52,
Organism=Drosophila melanogaster, GI21356309, Length=367, Percent_Identity=27.5204359673025, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI281365769, Length=242, Percent_Identity=27.2727272727273, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24660002, Length=242, Percent_Identity=27.2727272727273, Blast_Score=77, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000092
- InterPro:   IPR017446
- InterPro:   IPR014120
- InterPro:   IPR008949 [H]

Pfam domain/function: PF00348 polyprenyl_synt [H]

EC number: 2.5.1.- [C]

Molecular weight: Translated: 35529; Mature: 35398

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS00723 POLYPRENYL_SYNTHET_1 ; PS00444 POLYPRENYL_SYNTHET_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSVTSLFDPVEADLAILVDNLKDLVRAQHPVLFAAAEHLFQAGGKRMRPAIVLLLSRAL
CCCHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
LPDQDLTPRHRRLAEITEMIHTASLLHDDVVDDSGVRRGVPSVHSLFGNRIAIQAGDFLF
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCHHHHHHCCEEEEEECCEEE
AQASWYLANLDNLEVVKLLSEVIKDFAEGEIQQGINCFDTSLTLEAYLEKSYYKTASLMA
EEHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
NSAKAAGVLSGTSLQVNQDLYAYGRCVGLAFQIVDDILDFTGSTNALGKPACSDLRSGNL
HCHHHHHEECCCCEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCC
TAPVLFAIAEKPYLKVLIDRHLEEEEDLDEAIALVNDSQGIPKSRALAEQFAHQAVHHLD
CHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
FLPASDSRQALIDLTEYILKRLY
CCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TSVTSLFDPVEADLAILVDNLKDLVRAQHPVLFAAAEHLFQAGGKRMRPAIVLLLSRAL
CCHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
LPDQDLTPRHRRLAEITEMIHTASLLHDDVVDDSGVRRGVPSVHSLFGNRIAIQAGDFLF
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCHHHHHHCCEEEEEECCEEE
AQASWYLANLDNLEVVKLLSEVIKDFAEGEIQQGINCFDTSLTLEAYLEKSYYKTASLMA
EEHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
NSAKAAGVLSGTSLQVNQDLYAYGRCVGLAFQIVDDILDFTGSTNALGKPACSDLRSGNL
HCHHHHHEECCCCEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCC
TAPVLFAIAEKPYLKVLIDRHLEEEEDLDEAIALVNDSQGIPKSRALAEQFAHQAVHHLD
CHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
FLPASDSRQALIDLTEYILKRLY
CCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: trans-polyisoprenyln-PP; Delta3-isopentenyl-PP [C]

Specific reaction: trans-polyisoprenyln-PP + Delta3-isopentenyl-PP = trans-polyisoprenyln-PP + pyrophosphate [C]

General reaction: Transferring alkyl or aryl groups, other than methyl groups [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]