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The map label for this gene is 158337475

Identifier: 158337475

GI number: 158337475

Start: 4383112

End: 4384506

Strand: Direct

Name: 158337475

Synonym: AM1_4355

Alternate gene names: NA

Gene position: 4383112-4384506 (Clockwise)

Preceding gene: 158337474

Following gene: 158337485

Centisome position: 67.39

GC content: 48.1

Gene sequence:

>1395_bases
ATGAGCGTATCTTTATCTCGCCCTCCCCTGTGGTTTTGGATAGGAATCAGTTGCGTTTGGATCTTTGCCTTAGCCTTCCG
TTTTTGGGGATTAGAACGGTTTAATACCCTCGTGTTTGATGAGGTCTACTTTGCAAAGTTTGGCCATAACTACCTCACCC
AAACGGAATTTTTTGATGCTCATCCTCCGTTAGGCAAGTATTTAATTGCCTTGGGCATCGCCCTCAAGGGCTTTAACACT
TGGGGATTTCGATGGATGAATGCTCTGATTGGGGCTACGATTCCGCTGATCCTGTCGGGCATTGCCTATCAACTCTGCAA
GCGCCCCAGCTATGCTTTGATCACCGCTGTCTTAGCGAGTTTAGATGGTCTCCTTTTGGTGGAATCACGGTATGCCCTGC
TCAATGTCCACATCCTATTTTTTGGTCTGTTGGCCCATTGGTTGGTCTTAATCTCCCTCAACCATCAAGGGATGCAGCGG
AATGGGTGGCTGGCAGCTGCGGGTATTAGTTTTGGGGCAGCGATAGCCGTCAAATGGAATGGCTTAGGGCTTTTACTCGG
CCTTTATCTGCTGTGGTTGGTGGCGAAAGGCGGTCAGATATGGTTGGGATCGTCAGAGACCCCAAAGCGACGATTACCCC
TTCAAAAATTATCAGAGCTATCCTGGCTGCAGATGTTTGTGTATCTGCCTGCGATCGCACTCTTTGTCTACGGCATTTTA
TGGCTTCCCCATTTAGCTCAAAACCCTGAATTTAACCTTTGGCAGGTCCATCAAGAAATCTTTAACTACCATCGGCGAGT
CGGAGGAGATGAGGTCCATCCCTACTGTTCGTCTTGGTATACCTGGCCTTTACTGCTCAAGCCCATTAGCTATTTTTATC
AAGTTACCCAAAGCACTCTAGAACCGTTGCCCGTCACGGGTCCTCCTTTGCCTCAAGATGCGGTGAAATGGATTTACAGT
GTGTATGCGATTGGCAACCCCTTTCTATGGTGGTCGAGCACCATTGCTATCTGCGCCTTATTAGTCTTGGGAAGGTTACA
GATCCATCACAACCGAGTTCGACATATTAAAGGGCTTTATCCAACTAGCCACTCTTCTGATGAACAGAGTTGGATTTCTC
TATATTTGGGCGTGAACTATTTGGCTAATTTTTTGCCTTGGGTGGGGGTGAGTCGATGTACGTTTTTGTACCACTATATG
CCCGCATCCATGTTTACCAGCCTCGCCTTGGCCTGGTATATCGAGGGTTGGCTGCGGGTCTCAAACAAGTGGATGCGGCG
GCTGGCTGTGGCTGTACTAGTGCTTAGCCTAGTTAGCTTTGTAATCTGTTTACCGATTTTCTTAGGGCTACCGATATCGC
CCATGATGTGGCGACTTTTAAGAGCCAAGGGTTAA

Upstream 100 bases:

>100_bases
AAATACTCAAGTCGGCCAAAATCTACAGCTTGTCCTCAAGCGTGGTGAACGCACTCAGCAGATTGCTGTGCGGACAGCAG
CCCTGGAAAATGCGGCCTAG

Downstream 100 bases:

>100_bases
GTCGATTGACTGGTTAGGGCTTCGGGTTCCAACTTGACTTCTTCAATGGCGCCAGGCTCTCCCATAAGTTGGGCGGGTTT
TTTATTGACGGCCATCATAA

Product: dolichyl-phosphate-mannose-protein mannosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 464; Mature: 463

Protein sequence:

>464_residues
MSVSLSRPPLWFWIGISCVWIFALAFRFWGLERFNTLVFDEVYFAKFGHNYLTQTEFFDAHPPLGKYLIALGIALKGFNT
WGFRWMNALIGATIPLILSGIAYQLCKRPSYALITAVLASLDGLLLVESRYALLNVHILFFGLLAHWLVLISLNHQGMQR
NGWLAAAGISFGAAIAVKWNGLGLLLGLYLLWLVAKGGQIWLGSSETPKRRLPLQKLSELSWLQMFVYLPAIALFVYGIL
WLPHLAQNPEFNLWQVHQEIFNYHRRVGGDEVHPYCSSWYTWPLLLKPISYFYQVTQSTLEPLPVTGPPLPQDAVKWIYS
VYAIGNPFLWWSSTIAICALLVLGRLQIHHNRVRHIKGLYPTSHSSDEQSWISLYLGVNYLANFLPWVGVSRCTFLYHYM
PASMFTSLALAWYIEGWLRVSNKWMRRLAVAVLVLSLVSFVICLPIFLGLPISPMMWRLLRAKG

Sequences:

>Translated_464_residues
MSVSLSRPPLWFWIGISCVWIFALAFRFWGLERFNTLVFDEVYFAKFGHNYLTQTEFFDAHPPLGKYLIALGIALKGFNT
WGFRWMNALIGATIPLILSGIAYQLCKRPSYALITAVLASLDGLLLVESRYALLNVHILFFGLLAHWLVLISLNHQGMQR
NGWLAAAGISFGAAIAVKWNGLGLLLGLYLLWLVAKGGQIWLGSSETPKRRLPLQKLSELSWLQMFVYLPAIALFVYGIL
WLPHLAQNPEFNLWQVHQEIFNYHRRVGGDEVHPYCSSWYTWPLLLKPISYFYQVTQSTLEPLPVTGPPLPQDAVKWIYS
VYAIGNPFLWWSSTIAICALLVLGRLQIHHNRVRHIKGLYPTSHSSDEQSWISLYLGVNYLANFLPWVGVSRCTFLYHYM
PASMFTSLALAWYIEGWLRVSNKWMRRLAVAVLVLSLVSFVICLPIFLGLPISPMMWRLLRAKG
>Mature_463_residues
SVSLSRPPLWFWIGISCVWIFALAFRFWGLERFNTLVFDEVYFAKFGHNYLTQTEFFDAHPPLGKYLIALGIALKGFNTW
GFRWMNALIGATIPLILSGIAYQLCKRPSYALITAVLASLDGLLLVESRYALLNVHILFFGLLAHWLVLISLNHQGMQRN
GWLAAAGISFGAAIAVKWNGLGLLLGLYLLWLVAKGGQIWLGSSETPKRRLPLQKLSELSWLQMFVYLPAIALFVYGILW
LPHLAQNPEFNLWQVHQEIFNYHRRVGGDEVHPYCSSWYTWPLLLKPISYFYQVTQSTLEPLPVTGPPLPQDAVKWIYSV
YAIGNPFLWWSSTIAICALLVLGRLQIHHNRVRHIKGLYPTSHSSDEQSWISLYLGVNYLANFLPWVGVSRCTFLYHYMP
ASMFTSLALAWYIEGWLRVSNKWMRRLAVAVLVLSLVSFVICLPIFLGLPISPMMWRLLRAKG

Specific function: Unknown

COG id: COG1928

COG function: function code O; Dolichyl-phosphate-mannose--protein O-mannosyl transferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 39 family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6321638, Length=198, Percent_Identity=30.8080808080808, Blast_Score=76, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6320107, Length=198, Percent_Identity=29.2929292929293, Blast_Score=67, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6319296, Length=192, Percent_Identity=30.7291666666667, Blast_Score=64, Evalue=5e-11,
Organism=Drosophila melanogaster, GI20128815, Length=209, Percent_Identity=31.1004784688995, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003342 [H]

Pfam domain/function: PF02366 PMT [H]

EC number: NA

Molecular weight: Translated: 53068; Mature: 52937

Theoretical pI: Translated: 9.79; Mature: 9.79

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVSLSRPPLWFWIGISCVWIFALAFRFWGLERFNTLVFDEVYFAKFGHNYLTQTEFFDA
CCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCC
HPPLGKYLIALGIALKGFNTWGFRWMNALIGATIPLILSGIAYQLCKRPSYALITAVLAS
CCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
LDGLLLVESRYALLNVHILFFGLLAHWLVLISLNHQGMQRNGWLAAAGISFGAAIAVKWN
CCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCEEEEEEEC
GLGLLLGLYLLWLVAKGGQIWLGSSETPKRRLPLQKLSELSWLQMFVYLPAIALFVYGIL
CHHHHHHHHHHHHHHCCCEEEECCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
WLPHLAQNPEFNLWQVHQEIFNYHRRVGGDEVHPYCSSWYTWPLLLKPISYFYQVTQSTL
HHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHC
EPLPVTGPPLPQDAVKWIYSVYAIGNPFLWWSSTIAICALLVLGRLQIHHNRVRHIKGLY
CCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PTSHSSDEQSWISLYLGVNYLANFLPWVGVSRCTFLYHYMPASMFTSLALAWYIEGWLRV
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SNKWMRRLAVAVLVLSLVSFVICLPIFLGLPISPMMWRLLRAKG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCC
>Mature Secondary Structure 
SVSLSRPPLWFWIGISCVWIFALAFRFWGLERFNTLVFDEVYFAKFGHNYLTQTEFFDA
CCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCC
HPPLGKYLIALGIALKGFNTWGFRWMNALIGATIPLILSGIAYQLCKRPSYALITAVLAS
CCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
LDGLLLVESRYALLNVHILFFGLLAHWLVLISLNHQGMQRNGWLAAAGISFGAAIAVKWN
CCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCEEEEEEEC
GLGLLLGLYLLWLVAKGGQIWLGSSETPKRRLPLQKLSELSWLQMFVYLPAIALFVYGIL
CHHHHHHHHHHHHHHCCCEEEECCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
WLPHLAQNPEFNLWQVHQEIFNYHRRVGGDEVHPYCSSWYTWPLLLKPISYFYQVTQSTL
HHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHC
EPLPVTGPPLPQDAVKWIYSVYAIGNPFLWWSSTIAICALLVLGRLQIHHNRVRHIKGLY
CCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PTSHSSDEQSWISLYLGVNYLANFLPWVGVSRCTFLYHYMPASMFTSLALAWYIEGWLRV
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SNKWMRRLAVAVLVLSLVSFVICLPIFLGLPISPMMWRLLRAKG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]