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The map label for this gene is nadB [H]

Identifier: 158337092

GI number: 158337092

Start: 4014369

End: 4016036

Strand: Reverse

Name: nadB [H]

Synonym: AM1_3965

Alternate gene names: 158337092

Gene position: 4016036-4014369 (Counterclockwise)

Preceding gene: 158337093

Following gene: 158337090

Centisome position: 61.75

GC content: 52.46

Gene sequence:

>1668_bases
TTGTCACAAGATCTCCATACTCAAGGGTCTTCCCACTTTGATGTCCTCGTTGTCGGGGGCGGTGCTGCAGGGCTGTATAC
CGCCTTGTCGCTCCCCTCACACATTAGGGTAGGCCTGATTACCAAAGATAGTTTGTCCCGTTCTGCTAGCGATTGGGCCC
AGGGTGGTATTGCAGCTGCCTTTGATAAAGGTGACTCCCCAAAACTCCATGCCCAAGATACGGTGAATGCAGGCGTAGGC
CTATGTGAACCGAGGGCCGTTAATTTTCTAGTACAGCAGGCCCCCCAACAGGTAGATGCATTGTTGGAAATGGGAATTGC
CTTCGATCGTCGCCAAGATCAGCAATTAGCTGCGACTTTAGAAGCGGCGCATTCTCGTCCTCGTGTTCTCCATGCCGCTG
ATACAACGGGAAGAGCCTTAATCAAAACCCTGACGGCCCAAATGTGGCAGCGTTCGAATATTGAAGTGTTGGCAGATACC
TTCACCCTAGAGCTGTGGCGACATTCTCAAACAGGACGTTGCCAAGGCATCTGCATACTGTCGGCAGGCCAGATTTCTTG
GGTGTCTGCGGCGGCTGTTATTTTGGCCACGGGAGGCGGCGGTCAAGTCTTTTCCCAAACTACCAATCCAGCCTTAAGTA
CAGGGGATGGAGTCGCAATGGGGTGGCGGGCAGGAGCCCAGCTCCGAGATTTAGAGTTTTTCCAATTTCATCCCACGGCT
TTAACGCTGCCGGGTGCACCCCGATTTCTAATCAGTGAAGCGGTACGGGGTGAAGGCGCCCACTTATTAGACGCCTCTGG
TCACCGATTTATGTTTGACTATCATCCCCAGGGGGAACTAGCACCTAGGGATGTGGTTAGTCGGTCTATTTTTACCCATT
TGCAGGCGTCTGAGTCCCAGACCCATCAGGTATGGCTGGATTTAAGACCCATTGCCCCTGAGCAAATCCAGCGGCGGTTT
CCCAAAATTATTCAGGTTTGCCAGAAATGGGGGGTTGATGTTTATCAGCAGCCCATTCCAGTTTCGCCAGCAGCTCACTA
CTGGATGGGGGGAATACAGACCGATTTACAAAGTCAAACCTCTATTCCAGGACTCTATGCAGTTGGAGAAGTGGCTAGCA
CGGGCGTTCATGGGGCTAACCGGTTGGCGAGTAACTCTCTTTTAGAATGTTTGGTGTTTGCGGCTGAGTTTGCCCATCTT
GATTTATCGTCTATCCCGACAGCAGATATCACCTCAACGGAAACCTTAGCCAGTGACGATCTCACGATTGAGCCACAGGA
CGAAGCCATGTTGGCTGAAATTCGGACTCAGCTCCCTGAAGTGCTGTGGAATAGCGCTGGAATTTCCCGCTCCGGCGATC
AGATTCAGCGTGGGATCGCACGGGTGCATCAGTGGCGACAAGCCTTCCTCAGCTCTCCCTTGTCCCAGCAACTCAGCAGC
ATCGCGCCAGGGCAAACGGTTACAGTTAACCCCGATATCCCCGTGCGCGCTTGGGCAGAAACTCAGAACTTGCTGGATAT
TGGTTACTTAATCCTCAAAAGTGCTCACTTCCGCACCGAAAGCCGAGGCGGACATTATCGAGCCGACTATCCCAAATCGC
AAGAGCAGTGGCAAGCTCATACAGTGGTCAAGCAAGAAACCTGGCAGCAGATTCCCTTAGAGTCTTAA

Upstream 100 bases:

>100_bases
TTGTACAATTGCACTCTCTGCCTACGCAGTCGTTCATTTGACCACTGCTTTCAGGTGGGGAGTATTTTTTATGCTGCATT
ACAGCAATTTTTCTTGAACC

Downstream 100 bases:

>100_bases
AGGTTTAGCTAAACCGCTTGAGCTGAATCCGATAGCGCTCTTTTTTGGTGATTTGCACCTCACCCAATTCCAAACGCCCT
TTGCCCCGGATCGTCACTAA

Product: L-aspartate oxidase

Products: NA

Alternate protein names: LASPO; Quinolinate synthase B [H]

Number of amino acids: Translated: 555; Mature: 554

Protein sequence:

>555_residues
MSQDLHTQGSSHFDVLVVGGGAAGLYTALSLPSHIRVGLITKDSLSRSASDWAQGGIAAAFDKGDSPKLHAQDTVNAGVG
LCEPRAVNFLVQQAPQQVDALLEMGIAFDRRQDQQLAATLEAAHSRPRVLHAADTTGRALIKTLTAQMWQRSNIEVLADT
FTLELWRHSQTGRCQGICILSAGQISWVSAAAVILATGGGGQVFSQTTNPALSTGDGVAMGWRAGAQLRDLEFFQFHPTA
LTLPGAPRFLISEAVRGEGAHLLDASGHRFMFDYHPQGELAPRDVVSRSIFTHLQASESQTHQVWLDLRPIAPEQIQRRF
PKIIQVCQKWGVDVYQQPIPVSPAAHYWMGGIQTDLQSQTSIPGLYAVGEVASTGVHGANRLASNSLLECLVFAAEFAHL
DLSSIPTADITSTETLASDDLTIEPQDEAMLAEIRTQLPEVLWNSAGISRSGDQIQRGIARVHQWRQAFLSSPLSQQLSS
IAPGQTVTVNPDIPVRAWAETQNLLDIGYLILKSAHFRTESRGGHYRADYPKSQEQWQAHTVVKQETWQQIPLES

Sequences:

>Translated_555_residues
MSQDLHTQGSSHFDVLVVGGGAAGLYTALSLPSHIRVGLITKDSLSRSASDWAQGGIAAAFDKGDSPKLHAQDTVNAGVG
LCEPRAVNFLVQQAPQQVDALLEMGIAFDRRQDQQLAATLEAAHSRPRVLHAADTTGRALIKTLTAQMWQRSNIEVLADT
FTLELWRHSQTGRCQGICILSAGQISWVSAAAVILATGGGGQVFSQTTNPALSTGDGVAMGWRAGAQLRDLEFFQFHPTA
LTLPGAPRFLISEAVRGEGAHLLDASGHRFMFDYHPQGELAPRDVVSRSIFTHLQASESQTHQVWLDLRPIAPEQIQRRF
PKIIQVCQKWGVDVYQQPIPVSPAAHYWMGGIQTDLQSQTSIPGLYAVGEVASTGVHGANRLASNSLLECLVFAAEFAHL
DLSSIPTADITSTETLASDDLTIEPQDEAMLAEIRTQLPEVLWNSAGISRSGDQIQRGIARVHQWRQAFLSSPLSQQLSS
IAPGQTVTVNPDIPVRAWAETQNLLDIGYLILKSAHFRTESRGGHYRADYPKSQEQWQAHTVVKQETWQQIPLES
>Mature_554_residues
SQDLHTQGSSHFDVLVVGGGAAGLYTALSLPSHIRVGLITKDSLSRSASDWAQGGIAAAFDKGDSPKLHAQDTVNAGVGL
CEPRAVNFLVQQAPQQVDALLEMGIAFDRRQDQQLAATLEAAHSRPRVLHAADTTGRALIKTLTAQMWQRSNIEVLADTF
TLELWRHSQTGRCQGICILSAGQISWVSAAAVILATGGGGQVFSQTTNPALSTGDGVAMGWRAGAQLRDLEFFQFHPTAL
TLPGAPRFLISEAVRGEGAHLLDASGHRFMFDYHPQGELAPRDVVSRSIFTHLQASESQTHQVWLDLRPIAPEQIQRRFP
KIIQVCQKWGVDVYQQPIPVSPAAHYWMGGIQTDLQSQTSIPGLYAVGEVASTGVHGANRLASNSLLECLVFAAEFAHLD
LSSIPTADITSTETLASDDLTIEPQDEAMLAEIRTQLPEVLWNSAGISRSGDQIQRGIARVHQWRQAFLSSPLSQQLSSI
APGQTVTVNPDIPVRAWAETQNLLDIGYLILKSAHFRTESRGGHYRADYPKSQEQWQAHTVVKQETWQQIPLES

Specific function: Catalyzes the oxidation of L-aspartate to iminoaspartate [H]

COG id: COG0029

COG function: function code H; Aspartate oxidase

Gene ontology:
GO:0005737: L-aspartate oxidase
GO:0008734: L-aspartate oxidase
GO:0009055: L-aspartate oxidase
GO:0009435: L-aspartate oxidase
GO:0016491: L-aspartate oxidase
GO:0055114: L-aspartate oxidase

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily [H]

Homologues:

Organism=Homo sapiens, GI156416003, Length=549, Percent_Identity=32.7868852459016, Blast_Score=234, Evalue=1e-61,
Organism=Escherichia coli, GI1788928, Length=540, Percent_Identity=37.962962962963, Blast_Score=349, Evalue=3e-97,
Organism=Escherichia coli, GI1790597, Length=522, Percent_Identity=32.7586206896552, Blast_Score=242, Evalue=5e-65,
Organism=Escherichia coli, GI1786942, Length=545, Percent_Identity=32.2935779816514, Blast_Score=241, Evalue=9e-65,
Organism=Caenorhabditis elegans, GI17505833, Length=539, Percent_Identity=32.0964749536178, Blast_Score=232, Evalue=4e-61,
Organism=Caenorhabditis elegans, GI17550100, Length=552, Percent_Identity=31.3405797101449, Blast_Score=231, Evalue=7e-61,
Organism=Caenorhabditis elegans, GI71986328, Length=420, Percent_Identity=29.2857142857143, Blast_Score=121, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6322416, Length=551, Percent_Identity=32.486388384755, Blast_Score=238, Evalue=2e-63,
Organism=Saccharomyces cerevisiae, GI6322701, Length=551, Percent_Identity=31.7604355716878, Blast_Score=235, Evalue=1e-62,
Organism=Saccharomyces cerevisiae, GI6320788, Length=477, Percent_Identity=26.8343815513627, Blast_Score=105, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6322511, Length=472, Percent_Identity=24.7881355932203, Blast_Score=103, Evalue=5e-23,
Organism=Drosophila melanogaster, GI17137288, Length=537, Percent_Identity=32.4022346368715, Blast_Score=242, Evalue=6e-64,
Organism=Drosophila melanogaster, GI24655642, Length=537, Percent_Identity=32.4022346368715, Blast_Score=242, Evalue=6e-64,
Organism=Drosophila melanogaster, GI24655647, Length=537, Percent_Identity=32.4022346368715, Blast_Score=242, Evalue=6e-64,
Organism=Drosophila melanogaster, GI24663005, Length=598, Percent_Identity=30.4347826086957, Blast_Score=209, Evalue=3e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003953
- InterPro:   IPR013027
- InterPro:   IPR015939
- InterPro:   IPR004112
- InterPro:   IPR005288 [H]

Pfam domain/function: PF00890 FAD_binding_2; PF02910 Succ_DH_flav_C [H]

EC number: =1.4.3.16 [H]

Molecular weight: Translated: 60437; Mature: 60305

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQDLHTQGSSHFDVLVVGGGAAGLYTALSLPSHIRVGLITKDSLSRSASDWAQGGIAAA
CCCCCCCCCCCCEEEEEECCCHHHHHHHHCCCCCEEEEEEEHHHHHCCHHHHHCCCEEEE
FDKGDSPKLHAQDTVNAGVGLCEPRAVNFLVQQAPQQVDALLEMGIAFDRRQDQQLAATL
ECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
EAAHSRPRVLHAADTTGRALIKTLTAQMWQRSNIEVLADTFTLELWRHSQTGRCQGICIL
HHHCCCCCEEEECCCCHHHHHHHHHHHHHCCCCCEEEEHHHEEEEHHCCCCCCCCEEEEE
SAGQISWVSAAAVILATGGGGQVFSQTTNPALSTGDGVAMGWRAGAQLRDLEFFQFHPTA
ECCCCHHHEEEEEEEEECCCCCEEECCCCCCCCCCCCEEECCCCCCCEECCEEEEECCCE
LTLPGAPRFLISEAVRGEGAHLLDASGHRFMFDYHPQGELAPRDVVSRSIFTHLQASESQ
EECCCCCHHHHHHHHCCCCCEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCC
THQVWLDLRPIAPEQIQRRFPKIIQVCQKWGVDVYQQPIPVSPAAHYWMGGIQTDLQSQT
CEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCHHHHHHCCHHHHHHHHC
SIPGLYAVGEVASTGVHGANRLASNSLLECLVFAAEFAHLDLSSIPTADITSTETLASDD
CCCCCEEHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCCHHCCCCC
LTIEPQDEAMLAEIRTQLPEVLWNSAGISRSGDQIQRGIARVHQWRQAFLSSPLSQQLSS
CEECCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
IAPGQTVTVNPDIPVRAWAETQNLLDIGYLILKSAHFRTESRGGHYRADYPKSQEQWQAH
CCCCCEEEECCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCHHHHHHH
TVVKQETWQQIPLES
HHHHHHHHHCCCCCC
>Mature Secondary Structure 
SQDLHTQGSSHFDVLVVGGGAAGLYTALSLPSHIRVGLITKDSLSRSASDWAQGGIAAA
CCCCCCCCCCCEEEEEECCCHHHHHHHHCCCCCEEEEEEEHHHHHCCHHHHHCCCEEEE
FDKGDSPKLHAQDTVNAGVGLCEPRAVNFLVQQAPQQVDALLEMGIAFDRRQDQQLAATL
ECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
EAAHSRPRVLHAADTTGRALIKTLTAQMWQRSNIEVLADTFTLELWRHSQTGRCQGICIL
HHHCCCCCEEEECCCCHHHHHHHHHHHHHCCCCCEEEEHHHEEEEHHCCCCCCCCEEEEE
SAGQISWVSAAAVILATGGGGQVFSQTTNPALSTGDGVAMGWRAGAQLRDLEFFQFHPTA
ECCCCHHHEEEEEEEEECCCCCEEECCCCCCCCCCCCEEECCCCCCCEECCEEEEECCCE
LTLPGAPRFLISEAVRGEGAHLLDASGHRFMFDYHPQGELAPRDVVSRSIFTHLQASESQ
EECCCCCHHHHHHHHCCCCCEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCC
THQVWLDLRPIAPEQIQRRFPKIIQVCQKWGVDVYQQPIPVSPAAHYWMGGIQTDLQSQT
CEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCHHHHHHCCHHHHHHHHC
SIPGLYAVGEVASTGVHGANRLASNSLLECLVFAAEFAHLDLSSIPTADITSTETLASDD
CCCCCEEHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCCHHCCCCC
LTIEPQDEAMLAEIRTQLPEVLWNSAGISRSGDQIQRGIARVHQWRQAFLSSPLSQQLSS
CEECCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
IAPGQTVTVNPDIPVRAWAETQNLLDIGYLILKSAHFRTESRGGHYRADYPKSQEQWQAH
CCCCCEEEECCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCHHHHHHH
TVVKQETWQQIPLES
HHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]