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The map label for this gene is 158337072

Identifier: 158337072

GI number: 158337072

Start: 3994118

End: 3995902

Strand: Reverse

Name: 158337072

Synonym: AM1_3945

Alternate gene names: NA

Gene position: 3995902-3994118 (Counterclockwise)

Preceding gene: 158337074

Following gene: 158337071

Centisome position: 61.44

GC content: 51.26

Gene sequence:

>1785_bases
ATGGCAAGTCATTCTATCTTTACTTCAACCCTTCTCAAGAAAAAGCTTTTAAGCTCAACTCTACTGCTCTGGGGATTGGC
AACAGTAAACGGAGTGATGCCTGATCGAGTCCGAGCCCAAACCTCATCTACTTCGACGCCATCATCAGCGCCCACCCAAC
CTCAGCCCTCCTCTGCTAAGACGCCAACACAGCCGTCTTCACTTACCCCATTGCCCAACGAATTTATCGAGAAGGCTCCT
GGACCGATCCGCACGCCAGACCCCCGCAAAGTCACTGGGCCATCTCAACCCTCTTCAACTTCAGCAGAAAAAGCTGAGGT
CAAGCCTGCTCAAAATCAGCCAGCTGAAGCTAAGCCTGCTCAAACCAAAGTCACTGAAACCAAGCCAGCTGAAGCTAAGC
CTGCTCAAACCAAACCTTCAGCGGGTCAGGCTGCTCCGGCCAAACCAGCAGCACAACCCGCAAAACCCAAAGCGCCGACG
GCTAAACCACCCACAACCCCCAAAGCACCAACCGCTAAATCACCTACAACCCCCAAAGCGCCGACGGCTAAACCACCCAC
AAAAACCAAGCCTGTTGCCCAGCCGACCCAAAAGGCCGCACCGAAAGCAGTCAAAAAAACTCAGCCGGCCAAGCCCAAGG
CAGCAGCCAAATCGGGTAAAGGCGGTCAGCAGGCCCTGGCCCATTTACGCCAAGGCGTTGAAAAGTATGGCAAAGGGAAT
TTCAAAGGCGCCATTCAAGACTACGACAAAGCCATTCAAATCAATGGTAACTATGCCCTAGCCTATGTCAATCGTGGCTA
CGCCCATACGGTCTTAGGCAATAGCAAATCTGCGATCGCAGATTACACCAAGGTCATTCAACTCAACCCTAAAAATATTG
AGTTAACCAAAATCTATTTAAATCGGGGCTTAGCGTTTGCTGCGGCCAAGAACTACCCAGCAGCCCTCCAAGACTTTAAT
CAGGTCTTGCAGCGAGATGCCAAGAATCCGGAAGCGTACCTCAATCGAGGGCGCGCTCACGCGGCCAGCGGCAATCATCT
TGCCGCCATTCAAGACTATGGACAGGTGATTAAATTCCAGCCCAAGTCTGCTTTAGCTTACTTTAATCGTGGCGTCGCCT
ATAGCAAGGTGGGAGATAATGCCACAGCCCTGGCGGATTATTCGAAGGCTCTTCAACTGGATCCAAAATATGCCGCCGCC
TTGTATAACCGAGGCCTGGTCCAGCTCAATCAGGGGAACTCCCAAGACGCCATCGCAGATTTTACGGCATCCATTCAAAT
GGACACCAAATATGCCGCCGCCTATAAGAATCGCGGCACCGCCCATTTGAAAGCCGGTAATACTGAAGCTGCCATTGCAG
ATTTCACCCAGGCGATTACGTTCAATGCAGAAGATACCTTGGCTTACTACAACCGAGGCATTGCCCACAGCACGGCTGGC
CAGAACGAAGCTGCGATCGCAGATTACTCACAAGTGCTGAAACTCGATCCAAAATTTGCCGCTGCCTATACCAACCGAGG
CAATCTCCATGCTGCTCAAGGCGATCGAGACGCTGCCTTAAAGGACTATTCTCAAGCCATCGAGGCAAATCCTGAGAATG
CAACCGCCTATAATAATCGGGCTCTGATCCATTCAGCGCTCCGACAATACGAAGAAGCCTTATCTGACTATCAGCAAGCC
GCCAAAATCTATCAAGGCCAGGGATCTACTCAAGATTATGAGCGAGTCCAACCCCTGATTACAGAACTCAAAAAGCGAGT
TGAACGCCAAAAGAATCAATCCTAG

Upstream 100 bases:

>100_bases
GACCTCATTTCAGACGAAAAAGCGACTTCCTCATACTGTTTCACCCAGATCTCGCTATAGTAAGTCCAGAATATTCGTTG
GCTAGTTTATTTTTAGAGCG

Downstream 100 bases:

>100_bases
CGGCTCCTGACCTCAGCCTAGAAAAAATGGCTCCTGTTTCGCTATCAAAGCAGGCAGTCCTCTTTCGAGTGCTCCCGCAA
TTCTGTAAGCTGTTGAGGTA

Product: TPR domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 594; Mature: 593

Protein sequence:

>594_residues
MASHSIFTSTLLKKKLLSSTLLLWGLATVNGVMPDRVRAQTSSTSTPSSAPTQPQPSSAKTPTQPSSLTPLPNEFIEKAP
GPIRTPDPRKVTGPSQPSSTSAEKAEVKPAQNQPAEAKPAQTKVTETKPAEAKPAQTKPSAGQAAPAKPAAQPAKPKAPT
AKPPTTPKAPTAKSPTTPKAPTAKPPTKTKPVAQPTQKAAPKAVKKTQPAKPKAAAKSGKGGQQALAHLRQGVEKYGKGN
FKGAIQDYDKAIQINGNYALAYVNRGYAHTVLGNSKSAIADYTKVIQLNPKNIELTKIYLNRGLAFAAAKNYPAALQDFN
QVLQRDAKNPEAYLNRGRAHAASGNHLAAIQDYGQVIKFQPKSALAYFNRGVAYSKVGDNATALADYSKALQLDPKYAAA
LYNRGLVQLNQGNSQDAIADFTASIQMDTKYAAAYKNRGTAHLKAGNTEAAIADFTQAITFNAEDTLAYYNRGIAHSTAG
QNEAAIADYSQVLKLDPKFAAAYTNRGNLHAAQGDRDAALKDYSQAIEANPENATAYNNRALIHSALRQYEEALSDYQQA
AKIYQGQGSTQDYERVQPLITELKKRVERQKNQS

Sequences:

>Translated_594_residues
MASHSIFTSTLLKKKLLSSTLLLWGLATVNGVMPDRVRAQTSSTSTPSSAPTQPQPSSAKTPTQPSSLTPLPNEFIEKAP
GPIRTPDPRKVTGPSQPSSTSAEKAEVKPAQNQPAEAKPAQTKVTETKPAEAKPAQTKPSAGQAAPAKPAAQPAKPKAPT
AKPPTTPKAPTAKSPTTPKAPTAKPPTKTKPVAQPTQKAAPKAVKKTQPAKPKAAAKSGKGGQQALAHLRQGVEKYGKGN
FKGAIQDYDKAIQINGNYALAYVNRGYAHTVLGNSKSAIADYTKVIQLNPKNIELTKIYLNRGLAFAAAKNYPAALQDFN
QVLQRDAKNPEAYLNRGRAHAASGNHLAAIQDYGQVIKFQPKSALAYFNRGVAYSKVGDNATALADYSKALQLDPKYAAA
LYNRGLVQLNQGNSQDAIADFTASIQMDTKYAAAYKNRGTAHLKAGNTEAAIADFTQAITFNAEDTLAYYNRGIAHSTAG
QNEAAIADYSQVLKLDPKFAAAYTNRGNLHAAQGDRDAALKDYSQAIEANPENATAYNNRALIHSALRQYEEALSDYQQA
AKIYQGQGSTQDYERVQPLITELKKRVERQKNQS
>Mature_593_residues
ASHSIFTSTLLKKKLLSSTLLLWGLATVNGVMPDRVRAQTSSTSTPSSAPTQPQPSSAKTPTQPSSLTPLPNEFIEKAPG
PIRTPDPRKVTGPSQPSSTSAEKAEVKPAQNQPAEAKPAQTKVTETKPAEAKPAQTKPSAGQAAPAKPAAQPAKPKAPTA
KPPTTPKAPTAKSPTTPKAPTAKPPTKTKPVAQPTQKAAPKAVKKTQPAKPKAAAKSGKGGQQALAHLRQGVEKYGKGNF
KGAIQDYDKAIQINGNYALAYVNRGYAHTVLGNSKSAIADYTKVIQLNPKNIELTKIYLNRGLAFAAAKNYPAALQDFNQ
VLQRDAKNPEAYLNRGRAHAASGNHLAAIQDYGQVIKFQPKSALAYFNRGVAYSKVGDNATALADYSKALQLDPKYAAAL
YNRGLVQLNQGNSQDAIADFTASIQMDTKYAAAYKNRGTAHLKAGNTEAAIADFTQAITFNAEDTLAYYNRGIAHSTAGQ
NEAAIADYSQVLKLDPKFAAAYTNRGNLHAAQGDRDAALKDYSQAIEANPENATAYNNRALIHSALRQYEEALSDYQQAA
KIYQGQGSTQDYERVQPLITELKKRVERQKNQS

Specific function: Unknown

COG id: COG0457

COG function: function code R; FOG: TPR repeat

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 4 TPR repeats [H]

Homologues:

Organism=Homo sapiens, GI310131789, Length=322, Percent_Identity=31.6770186335404, Blast_Score=154, Evalue=3e-37,
Organism=Homo sapiens, GI310110582, Length=322, Percent_Identity=31.6770186335404, Blast_Score=154, Evalue=3e-37,
Organism=Homo sapiens, GI310123097, Length=322, Percent_Identity=31.6770186335404, Blast_Score=151, Evalue=2e-36,
Organism=Homo sapiens, GI32307148, Length=368, Percent_Identity=24.7282608695652, Blast_Score=107, Evalue=4e-23,
Organism=Homo sapiens, GI32307150, Length=368, Percent_Identity=24.7282608695652, Blast_Score=107, Evalue=4e-23,
Organism=Homo sapiens, GI170784867, Length=282, Percent_Identity=26.9503546099291, Blast_Score=96, Evalue=8e-20,
Organism=Homo sapiens, GI54607135, Length=266, Percent_Identity=26.3157894736842, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI296531396, Length=216, Percent_Identity=25.9259259259259, Blast_Score=80, Evalue=6e-15,
Organism=Homo sapiens, GI167466175, Length=554, Percent_Identity=20.7581227436823, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI167466177, Length=474, Percent_Identity=20.253164556962, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI301336134, Length=309, Percent_Identity=24.9190938511327, Blast_Score=74, Evalue=6e-13,
Organism=Homo sapiens, GI83415184, Length=309, Percent_Identity=24.9190938511327, Blast_Score=73, Evalue=8e-13,
Organism=Homo sapiens, GI5803181, Length=198, Percent_Identity=27.2727272727273, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI262206280, Length=334, Percent_Identity=25.748502994012, Blast_Score=69, Evalue=2e-11,
Organism=Homo sapiens, GI224028289, Length=351, Percent_Identity=25.9259259259259, Blast_Score=67, Evalue=6e-11,
Organism=Homo sapiens, GI5453980, Length=380, Percent_Identity=23.4210526315789, Blast_Score=67, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI115532690, Length=340, Percent_Identity=25.8823529411765, Blast_Score=107, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI115532692, Length=340, Percent_Identity=25.8823529411765, Blast_Score=104, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17551190, Length=338, Percent_Identity=21.8934911242604, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI17647755, Length=367, Percent_Identity=23.7057220708447, Blast_Score=96, Evalue=6e-20,
Organism=Drosophila melanogaster, GI24585827, Length=367, Percent_Identity=23.7057220708447, Blast_Score=96, Evalue=6e-20,
Organism=Drosophila melanogaster, GI24585829, Length=367, Percent_Identity=23.7057220708447, Blast_Score=96, Evalue=6e-20,
Organism=Drosophila melanogaster, GI17137540, Length=361, Percent_Identity=24.3767313019391, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24647123, Length=274, Percent_Identity=25.5474452554745, Blast_Score=71, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21355911, Length=225, Percent_Identity=26.6666666666667, Blast_Score=70, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF00515 TPR_1 [H]

EC number: NA

Molecular weight: Translated: 63510; Mature: 63379

Theoretical pI: Translated: 10.37; Mature: 10.37

Prosite motif: PS50005 TPR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
0.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASHSIFTSTLLKKKLLSSTLLLWGLATVNGVMPDRVRAQTSSTSTPSSAPTQPQPSSAK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCC
TPTQPSSLTPLPNEFIEKAPGPIRTPDPRKVTGPSQPSSTSAEKAEVKPAQNQPAEAKPA
CCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCC
QTKVTETKPAEAKPAQTKPSAGQAAPAKPAAQPAKPKAPTAKPPTTPKAPTAKSPTTPKA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PTAKPPTKTKPVAQPTQKAAPKAVKKTQPAKPKAAAKSGKGGQQALAHLRQGVEKYGKGN
CCCCCCCCCCCCCCCHHHHCCHHHHHCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHCCCC
FKGAIQDYDKAIQINGNYALAYVNRGYAHTVLGNSKSAIADYTKVIQLNPKNIELTKIYL
CCCHHHCCCCEEEECCCEEEEEEECCEEEEEECCCHHHHHHHHHEEEECCCCEEEEEEEE
NRGLAFAAAKNYPAALQDFNQVLQRDAKNPEAYLNRGRAHAASGNHLAAIQDYGQVIKFQ
CCCEEEEECCCCCHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCEEHHHHHCHHEEEC
PKSALAYFNRGVAYSKVGDNATALADYSKALQLDPKYAAALYNRGLVQLNQGNSQDAIAD
CHHHHHHHHCCCEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHCCCEEECCCCCCHHHHH
FTASIQMDTKYAAAYKNRGTAHLKAGNTEAAIADFTQAITFNAEDTLAYYNRGIAHSTAG
HHHEEEECHHHHHHHCCCCCEEEECCCCHHHHHHHHHHEECCCHHHHHHHHCCCCCCCCC
QNEAAIADYSQVLKLDPKFAAAYTNRGNLHAAQGDRDAALKDYSQAIEANPENATAYNNR
CCCHHHHHHHHHHHCCCCHHHHCCCCCCEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCH
ALIHSALRQYEEALSDYQQAAKIYQGQGSTQDYERVQPLITELKKRVERQKNQS
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ASHSIFTSTLLKKKLLSSTLLLWGLATVNGVMPDRVRAQTSSTSTPSSAPTQPQPSSAK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCC
TPTQPSSLTPLPNEFIEKAPGPIRTPDPRKVTGPSQPSSTSAEKAEVKPAQNQPAEAKPA
CCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCC
QTKVTETKPAEAKPAQTKPSAGQAAPAKPAAQPAKPKAPTAKPPTTPKAPTAKSPTTPKA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PTAKPPTKTKPVAQPTQKAAPKAVKKTQPAKPKAAAKSGKGGQQALAHLRQGVEKYGKGN
CCCCCCCCCCCCCCCHHHHCCHHHHHCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHCCCC
FKGAIQDYDKAIQINGNYALAYVNRGYAHTVLGNSKSAIADYTKVIQLNPKNIELTKIYL
CCCHHHCCCCEEEECCCEEEEEEECCEEEEEECCCHHHHHHHHHEEEECCCCEEEEEEEE
NRGLAFAAAKNYPAALQDFNQVLQRDAKNPEAYLNRGRAHAASGNHLAAIQDYGQVIKFQ
CCCEEEEECCCCCHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCEEHHHHHCHHEEEC
PKSALAYFNRGVAYSKVGDNATALADYSKALQLDPKYAAALYNRGLVQLNQGNSQDAIAD
CHHHHHHHHCCCEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHCCCEEECCCCCCHHHHH
FTASIQMDTKYAAAYKNRGTAHLKAGNTEAAIADFTQAITFNAEDTLAYYNRGIAHSTAG
HHHEEEECHHHHHHHCCCCCEEEECCCCHHHHHHHHHHEECCCHHHHHHHHCCCCCCCCC
QNEAAIADYSQVLKLDPKFAAAYTNRGNLHAAQGDRDAALKDYSQAIEANPENATAYNNR
CCCHHHHHHHHHHHCCCCHHHHCCCCCCEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCH
ALIHSALRQYEEALSDYQQAAKIYQGQGSTQDYERVQPLITELKKRVERQKNQS
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1368342; 8905231 [H]