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The map label for this gene is cph2 [H]

Identifier: 158336701

GI number: 158336701

Start: 3617786

End: 3618892

Strand: Direct

Name: cph2 [H]

Synonym: AM1_3569

Alternate gene names: 158336701

Gene position: 3617786-3618892 (Clockwise)

Preceding gene: 158336700

Following gene: 158336703

Centisome position: 55.63

GC content: 47.88

Gene sequence:

>1107_bases
GTGCGATTTACAGACAGCCGGGGAACACTGGATGTAATTCGCGAGATCAGCCGAACGGCCATGCAAGACGTCAATGCTCC
AACATCTCCATTTCCGGAAGTTTCCAGAACATCATCCTTAGGGAGCTCTGATCAGGATCGACCCGTTATTCTGATTGCTG
AAGATGATCGGATGACGCGAGCCATGATCAGTCATATTCTCACGAATGATGGATATCGGGTCGTGGAAGCCGAGGATGGA
GAAACCTGTTTGGCCGCTTACCAAAAGAGTCCTCCTAACCTAGTGCTACTAGACGCCATGATGCCAGGCATGAATGGCTT
TGAGTGCTGTGGTGAACTGATGAAGTTCCCTGAGAGTGCCTATACCCCCATTTTGATGATCACGGGATTAGAAGATCAGA
CCTCTGTTGATTGGGCCTTTGATGTGGGAGCATCAGACTACATTACGAAACCGATCCATTGGCCTGTTTTGCGACAGCGG
GTTCGTATTCAGCTAGAAAGAACCCAACTCCATAAACAGCTGGAAGAAGCTAACAAGCGCTTAACCTACCTAGCTTCAGT
TGATGAATTGACCCAACTTCCGAATCGCCGGGCTTTTACAGAAGCCCTTAACCGGGAATGGCGAAGGATGGCTCGGGAGA
AATCTAGCCTAGCCTTAATCATGATCGATATTGACTATTTCAAAGTCTATAACGATACCTATGGACACCCGGTTGGGGAT
AGTTGCTTATTTCAGGTGGCCCGGGTTATCCATACTTGTGTTAGGCGTCCTGCCGATCTACCGTCTCGATATGGGGGGGA
AGAATTTGCAGTAATTTTGCCGAATACTACTTTATCAGGAGCAATTCATGTTGCCGAAAATATGCGGTTGTCCGTACAAA
GACTCATGATTCCCCATAAAAACTCGGCAAATGGTCCCTATGTCTCTCTCAGTTTGGGGGTGGCCAGTGTCATTCCTGAT
ATCCAGGAAATGGAATCAGAGACTCCTTTGCTGTTGGCCGCAGACCAAGCGCTATACAAAGCCAAGGCCGAAGGCAGAAA
TCGTGTGTGTGTCGATCAAACATTGTCAACGATAGAAAGCGAACAACTCATCGTCGATTCTGTGTAA

Upstream 100 bases:

>100_bases
ATCAGCCGAGCCGATCAGGCCCTCTATCAAGCGAAACAATCTGGACGAGACCAGGTGGTTGCTCTATCGATAACGGAGTA
GGTTTTTCAGCAGGAGAAGA

Downstream 100 bases:

>100_bases
ACCACCTAATACAGCTCATACTTCAAGAACTGACAGGCAATGGAGCCATTGTTGATCGCCTTGCGCTGACAAGATTTGAG
GCCAATCGATTGAGATAAGG

Product: diguanylate cyclase

Products: NA

Alternate protein names: Bacteriophytochrome cph2 [H]

Number of amino acids: Translated: 368; Mature: 368

Protein sequence:

>368_residues
MRFTDSRGTLDVIREISRTAMQDVNAPTSPFPEVSRTSSLGSSDQDRPVILIAEDDRMTRAMISHILTNDGYRVVEAEDG
ETCLAAYQKSPPNLVLLDAMMPGMNGFECCGELMKFPESAYTPILMITGLEDQTSVDWAFDVGASDYITKPIHWPVLRQR
VRIQLERTQLHKQLEEANKRLTYLASVDELTQLPNRRAFTEALNREWRRMAREKSSLALIMIDIDYFKVYNDTYGHPVGD
SCLFQVARVIHTCVRRPADLPSRYGGEEFAVILPNTTLSGAIHVAENMRLSVQRLMIPHKNSANGPYVSLSLGVASVIPD
IQEMESETPLLLAADQALYKAKAEGRNRVCVDQTLSTIESEQLIVDSV

Sequences:

>Translated_368_residues
MRFTDSRGTLDVIREISRTAMQDVNAPTSPFPEVSRTSSLGSSDQDRPVILIAEDDRMTRAMISHILTNDGYRVVEAEDG
ETCLAAYQKSPPNLVLLDAMMPGMNGFECCGELMKFPESAYTPILMITGLEDQTSVDWAFDVGASDYITKPIHWPVLRQR
VRIQLERTQLHKQLEEANKRLTYLASVDELTQLPNRRAFTEALNREWRRMAREKSSLALIMIDIDYFKVYNDTYGHPVGD
SCLFQVARVIHTCVRRPADLPSRYGGEEFAVILPNTTLSGAIHVAENMRLSVQRLMIPHKNSANGPYVSLSLGVASVIPD
IQEMESETPLLLAADQALYKAKAEGRNRVCVDQTLSTIESEQLIVDSV
>Mature_368_residues
MRFTDSRGTLDVIREISRTAMQDVNAPTSPFPEVSRTSSLGSSDQDRPVILIAEDDRMTRAMISHILTNDGYRVVEAEDG
ETCLAAYQKSPPNLVLLDAMMPGMNGFECCGELMKFPESAYTPILMITGLEDQTSVDWAFDVGASDYITKPIHWPVLRQR
VRIQLERTQLHKQLEEANKRLTYLASVDELTQLPNRRAFTEALNREWRRMAREKSSLALIMIDIDYFKVYNDTYGHPVGD
SCLFQVARVIHTCVRRPADLPSRYGGEEFAVILPNTTLSGAIHVAENMRLSVQRLMIPHKNSANGPYVSLSLGVASVIPD
IQEMESETPLLLAADQALYKAKAEGRNRVCVDQTLSTIESEQLIVDSV

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: COG3706

COG function: function code T; Response regulator containing a CheY-like receiver domain and a GGDEF domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 GGDEF domains [H]

Homologues:

Organism=Escherichia coli, GI87081881, Length=187, Percent_Identity=39.572192513369, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1786584, Length=185, Percent_Identity=36.7567567567568, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI145693134, Length=186, Percent_Identity=34.4086021505376, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1787262, Length=179, Percent_Identity=35.195530726257, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI87082007, Length=174, Percent_Identity=36.7816091954023, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI1787802, Length=171, Percent_Identity=34.5029239766082, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI1787541, Length=175, Percent_Identity=33.7142857142857, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1787816, Length=168, Percent_Identity=33.3333333333333, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI87081977, Length=178, Percent_Identity=32.5842696629214, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1788381, Length=173, Percent_Identity=31.7919075144509, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1790863, Length=121, Percent_Identity=36.3636363636364, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1788394, Length=135, Percent_Identity=29.6296296296296, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1786599, Length=118, Percent_Identity=31.3559322033898, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788085, Length=186, Percent_Identity=28.494623655914, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI87081974, Length=161, Percent_Identity=29.8136645962733, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1787056, Length=165, Percent_Identity=31.5151515151515, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI87082012, Length=154, Percent_Identity=29.2207792207792, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1786911, Length=118, Percent_Identity=30.5084745762712, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1788956, Length=184, Percent_Identity=31.5217391304348, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1789809, Length=123, Percent_Identity=30.8943089430894, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR003018
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515 [H]

Pfam domain/function: PF00563 EAL; PF01590 GAF; PF00990 GGDEF; PF00360 Phytochrome [H]

EC number: NA

Molecular weight: Translated: 41269; Mature: 41269

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFTDSRGTLDVIREISRTAMQDVNAPTSPFPEVSRTSSLGSSDQDRPVILIAEDDRMTR
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCCCCCEEEEECCCHHHH
AMISHILTNDGYRVVEAEDGETCLAAYQKSPPNLVLLDAMMPGMNGFECCGELMKFPESA
HHHHHHHCCCCEEEEECCCCCHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCC
YTPILMITGLEDQTSVDWAFDVGASDYITKPIHWPVLRQRVRIQLERTQLHKQLEEANKR
CCCEEEEECCCCCCCCCEEEECCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTYLASVDELTQLPNRRAFTEALNREWRRMAREKSSLALIMIDIDYFKVYNDTYGHPVGD
EEEHCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEEEECCCCCCCCCH
SCLFQVARVIHTCVRRPADLPSRYGGEEFAVILPNTTLSGAIHVAENMRLSVQRLMIPHK
HHHHHHHHHHHHHHCCCCCCHHHCCCCEEEEEECCCCCCCCEEEHHHHHHHHHHHCCCCC
NSANGPYVSLSLGVASVIPDIQEMESETPLLLAADQALYKAKAEGRNRVCVDQTLSTIES
CCCCCCEEEEECCHHHHCCCHHHHCCCCCEEEECHHHHHHHHHCCCCCEEHHHHHHHHCC
EQLIVDSV
CCEEECCC
>Mature Secondary Structure
MRFTDSRGTLDVIREISRTAMQDVNAPTSPFPEVSRTSSLGSSDQDRPVILIAEDDRMTR
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCCCCCEEEEECCCHHHH
AMISHILTNDGYRVVEAEDGETCLAAYQKSPPNLVLLDAMMPGMNGFECCGELMKFPESA
HHHHHHHCCCCEEEEECCCCCHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCC
YTPILMITGLEDQTSVDWAFDVGASDYITKPIHWPVLRQRVRIQLERTQLHKQLEEANKR
CCCEEEEECCCCCCCCCEEEECCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTYLASVDELTQLPNRRAFTEALNREWRRMAREKSSLALIMIDIDYFKVYNDTYGHPVGD
EEEHCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEEEECCCCCCCCCH
SCLFQVARVIHTCVRRPADLPSRYGGEEFAVILPNTTLSGAIHVAENMRLSVQRLMIPHK
HHHHHHHHHHHHHHCCCCCCHHHCCCCEEEEEECCCCCCCCEEEHHHHHHHHHHHCCCCC
NSANGPYVSLSLGVASVIPDIQEMESETPLLLAADQALYKAKAEGRNRVCVDQTLSTIES
CCCCCCEEEEECCHHHHCCCHHHHCCCCCEEEECHHHHHHHHHCCCCCEEHHHHHHHHCC
EQLIVDSV
CCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 10978170; 11063585 [H]