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The map label for this gene is fur [H]

Identifier: 158336305

GI number: 158336305

Start: 3196390

End: 3196797

Strand: Reverse

Name: fur [H]

Synonym: AM1_3167

Alternate gene names: 158336305

Gene position: 3196797-3196390 (Counterclockwise)

Preceding gene: 158336308

Following gene: 158336304

Centisome position: 49.15

GC content: 43.87

Gene sequence:

>408_bases
ATGAAATCGCACCTTACTCGTAGTCAAAATACCGTTCTCAAACTTTTAAAGAAGTTGAATCGAGAGATTTCAGCTCAAGA
ACTTTATCTTGAGTTGCGCAAAGCCCAACTAACCTTGGGGCTAGCCACGGTTTATCGAGCATTAGATACTCTCAAGCTCA
GCGGTATCGTCCAAGCAAGGCTACTGAGCAATGGTGAAACCCTGTATACCGCTGCTCAACAAGATAGACATCATGTTACT
TGTCTACAATGCGGTGTTTCGATTCCCATCCAGGAAGAAGAATGTCCCGTTCATGAATTGGAAGATCAGCTCAAACAATC
CTCAAAGTTCGAAATTTTCTACCATACGCTAGAGTTTTTCGGCCTTTGCACGCCATGCCAACTCGAACAGTCGCATTCAA
AGCCTTAG

Upstream 100 bases:

>100_bases
GGAGCGCTCTCAATCATGTCTATCGATAGGCAATCGAGAATTTGAAGCACCCCATTCTCACCCCTTGACCATTGCATCAT
CAGCTATTGATGCCCTTTTC

Downstream 100 bases:

>100_bases
ATCTCTGAAGCGACTCATGCACGACATGGAATAGGATTTTTGCCCCATCAGACAATATAAAAGTTAAGATTTTTGTGGGT
TTATTAAGGATTTGGTGTCA

Product: ferric uptake regulation protein

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 135; Mature: 135

Protein sequence:

>135_residues
MKSHLTRSQNTVLKLLKKLNREISAQELYLELRKAQLTLGLATVYRALDTLKLSGIVQARLLSNGETLYTAAQQDRHHVT
CLQCGVSIPIQEEECPVHELEDQLKQSSKFEIFYHTLEFFGLCTPCQLEQSHSKP

Sequences:

>Translated_135_residues
MKSHLTRSQNTVLKLLKKLNREISAQELYLELRKAQLTLGLATVYRALDTLKLSGIVQARLLSNGETLYTAAQQDRHHVT
CLQCGVSIPIQEEECPVHELEDQLKQSSKFEIFYHTLEFFGLCTPCQLEQSHSKP
>Mature_135_residues
MKSHLTRSQNTVLKLLKKLNREISAQELYLELRKAQLTLGLATVYRALDTLKLSGIVQARLLSNGETLYTAAQQDRHHVT
CLQCGVSIPIQEEECPVHELEDQLKQSSKFEIFYHTLEFFGLCTPCQLEQSHSKP

Specific function: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes. Regulates the expression of the fbp protein [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

None

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 15411; Mature: 15411

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.7 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
3.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSHLTRSQNTVLKLLKKLNREISAQELYLELRKAQLTLGLATVYRALDTLKLSGIVQAR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLSNGETLYTAAQQDRHHVTCLQCGVSIPIQEEECPVHELEDQLKQSSKFEIFYHTLEFF
HHCCCCEEEEECCCCCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHH
GLCTPCQLEQSHSKP
CCCCCCCCCCCCCCC
>Mature Secondary Structure
MKSHLTRSQNTVLKLLKKLNREISAQELYLELRKAQLTLGLATVYRALDTLKLSGIVQAR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLSNGETLYTAAQQDRHHVTCLQCGVSIPIQEEECPVHELEDQLKQSSKFEIFYHTLEFF
HHCCCCEEEEECCCCCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHH
GLCTPCQLEQSHSKP
CCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8406856 [H]