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The map label for this gene is yjiA [H]

Identifier: 158334375

GI number: 158334375

Start: 1175024

End: 1176025

Strand: Reverse

Name: yjiA [H]

Synonym: AM1_1196

Alternate gene names: 158334375

Gene position: 1176025-1175024 (Counterclockwise)

Preceding gene: 158334376

Following gene: 158334374

Centisome position: 18.08

GC content: 51.4

Gene sequence:

>1002_bases
ATGGCATTGATCCAAAAGATTCCGGTTACCGTTTTGACGGGGTACTTGGGAGCAGGAAAAACCACGCTACTGAACCGCAT
TCTGACAGAAGAGCACCATCAGCGGATAGCGGTGATTGTCAACGAATTTGGTGAGGTCGGTATCGATCATCAGTTGGTGA
TTGATGCCGATGAAGAAGTCTTTGAAATGAACAACGGCTGCATCTGCTGCACCGTTCGCGGAGACTTAATTCGGATTATT
GGCAACCTGATGCAGCGGCGAGATCGCTTTGATCACTTAGTCATTGAAACGACGGGGCTTGCCGATCCAGCCCCCGTGAT
CCAGTCCTTTTTTGTGGATGAAGTGATGCTGCGGCAAACCCAGCTCGATGCTGTCGTCACTGTCGTAGATGCCAAGCATA
TTTGGGACCACTGGGACAGTAGTGAAGCCCAAGAGCAAATTGCCTTTGCGGATGTGATTTTGCTGAATAAGCAGGATTTA
GTATCACCAGAAATCCTGACGGCCCTGACGCAACGGGTAAGGAGCATTAATGCGATCGCAACCCTACATCCCACCACCCA
CTGCAGTGTTGACCTCACACAACTCCTGGGGGTTCAAGCCTTTAACCTCAGCCATGCCCTCAGTATCGACCCCGAGTTTT
TAGACGAAGATGCCCATGAGCATGATCAAACCGTTACTTCCGTTGCCATTACCGAGATGGGCACCGTAGACAGCGTCAAG
CTCAATCGATGGCTCTACCAGCTGGTCCAAGCTCGTGGTCCTGACCTGTTTCGGATGAAAGGCATTTTGGATATGGATGA
CGCCGATCGTCGGTTTGTTTTTCAAGGGGTGCATATGACCTTAGACGGCAGACCCGGTAAACCCTGGCGTCCGGGGGAAA
CCCGCCGCAATGAATTGGTCTTTATCGGCAGAAATCTAGATGAAGCCGAACTCCGTAACGAGTTCCTAAGCTGTTTGGCC
CAGCCCCTTTCCCCAACCTTGACCGCAGAGGTATACGCATGA

Upstream 100 bases:

>100_bases
GACTGCGCTCGACCAGCCGTTCTGGTTATGATCCCAATGCCCTCAACCGGACGATTGGATTTCGAGTCATGACGGTATTG
AGTTAGGGCAGGAGAACATA

Downstream 100 bases:

>100_bases
AACTACAGCATAATCTGGGGGGCCTGGAAGGGCTCGATCCCATCAACGTTGAAAAACAGGTGTTTGTGGAACCCTGGGAA
AAGCGCATCTTTGGTATCCA

Product: cobalamin synthesis protein/P47K

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MALIQKIPVTVLTGYLGAGKTTLLNRILTEEHHQRIAVIVNEFGEVGIDHQLVIDADEEVFEMNNGCICCTVRGDLIRII
GNLMQRRDRFDHLVIETTGLADPAPVIQSFFVDEVMLRQTQLDAVVTVVDAKHIWDHWDSSEAQEQIAFADVILLNKQDL
VSPEILTALTQRVRSINAIATLHPTTHCSVDLTQLLGVQAFNLSHALSIDPEFLDEDAHEHDQTVTSVAITEMGTVDSVK
LNRWLYQLVQARGPDLFRMKGILDMDDADRRFVFQGVHMTLDGRPGKPWRPGETRRNELVFIGRNLDEAELRNEFLSCLA
QPLSPTLTAEVYA

Sequences:

>Translated_333_residues
MALIQKIPVTVLTGYLGAGKTTLLNRILTEEHHQRIAVIVNEFGEVGIDHQLVIDADEEVFEMNNGCICCTVRGDLIRII
GNLMQRRDRFDHLVIETTGLADPAPVIQSFFVDEVMLRQTQLDAVVTVVDAKHIWDHWDSSEAQEQIAFADVILLNKQDL
VSPEILTALTQRVRSINAIATLHPTTHCSVDLTQLLGVQAFNLSHALSIDPEFLDEDAHEHDQTVTSVAITEMGTVDSVK
LNRWLYQLVQARGPDLFRMKGILDMDDADRRFVFQGVHMTLDGRPGKPWRPGETRRNELVFIGRNLDEAELRNEFLSCLA
QPLSPTLTAEVYA
>Mature_332_residues
ALIQKIPVTVLTGYLGAGKTTLLNRILTEEHHQRIAVIVNEFGEVGIDHQLVIDADEEVFEMNNGCICCTVRGDLIRIIG
NLMQRRDRFDHLVIETTGLADPAPVIQSFFVDEVMLRQTQLDAVVTVVDAKHIWDHWDSSEAQEQIAFADVILLNKQDLV
SPEILTALTQRVRSINAIATLHPTTHCSVDLTQLLGVQAFNLSHALSIDPEFLDEDAHEHDQTVTSVAITEMGTVDSVKL
NRWLYQLVQARGPDLFRMKGILDMDDADRRFVFQGVHMTLDGRPGKPWRPGETRRNELVFIGRNLDEAELRNEFLSCLAQ
PLSPTLTAEVYA

Specific function: Binds GTP. May function as GTP-dependent regulator [H]

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI33469141, Length=343, Percent_Identity=36.734693877551, Blast_Score=218, Evalue=4e-57,
Organism=Homo sapiens, GI126722884, Length=343, Percent_Identity=36.734693877551, Blast_Score=218, Evalue=6e-57,
Organism=Homo sapiens, GI148727351, Length=343, Percent_Identity=36.734693877551, Blast_Score=216, Evalue=3e-56,
Organism=Homo sapiens, GI146231952, Length=343, Percent_Identity=36.734693877551, Blast_Score=214, Evalue=7e-56,
Organism=Homo sapiens, GI223941779, Length=341, Percent_Identity=36.0703812316716, Blast_Score=206, Evalue=2e-53,
Organism=Homo sapiens, GI223941776, Length=328, Percent_Identity=35.3658536585366, Blast_Score=197, Evalue=1e-50,
Organism=Homo sapiens, GI119120938, Length=334, Percent_Identity=32.9341317365269, Blast_Score=172, Evalue=4e-43,
Organism=Homo sapiens, GI310124599, Length=192, Percent_Identity=30.2083333333333, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI310124603, Length=228, Percent_Identity=28.0701754385965, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI169184311, Length=152, Percent_Identity=29.6052631578947, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI87082430, Length=323, Percent_Identity=37.7708978328173, Blast_Score=189, Evalue=2e-49,
Organism=Escherichia coli, GI1788499, Length=248, Percent_Identity=30.241935483871, Blast_Score=98, Evalue=9e-22,
Organism=Saccharomyces cerevisiae, GI6324356, Length=361, Percent_Identity=29.0858725761773, Blast_Score=147, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 37424; Mature: 37293

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALIQKIPVTVLTGYLGAGKTTLLNRILTEEHHQRIAVIVNEFGEVGIDHQLVIDADEEV
CCCHHHCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHH
FEMNNGCICCTVRGDLIRIIGNLMQRRDRFDHLVIETTGLADPAPVIQSFFVDEVMLRQT
HHCCCCEEEEEECHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHHHHHH
QLDAVVTVVDAKHIWDHWDSSEAQEQIAFADVILLNKQDLVSPEILTALTQRVRSINAIA
HHHHHEEEHHHHHHHHCCCCHHHHHHHHHHHEEEECCHHCCCHHHHHHHHHHHHHHHHEE
TLHPTTHCSVDLTQLLGVQAFNLSHALSIDPEFLDEDAHEHDQTVTSVAITEMGTVDSVK
EECCCCCCCEEHHHHHCCHHCCCCCEEECCHHHHCCCHHHHHHHHHHHHHHHCCCCCHHH
LNRWLYQLVQARGPDLFRMKGILDMDDADRRFVFQGVHMTLDGRPGKPWRPGETRRNELV
HHHHHHHHHHHCCCCEEEECCCCCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCCCCEE
FIGRNLDEAELRNEFLSCLAQPLSPTLTAEVYA
EEECCCCHHHHHHHHHHHHHHCCCCCCEEEECC
>Mature Secondary Structure 
ALIQKIPVTVLTGYLGAGKTTLLNRILTEEHHQRIAVIVNEFGEVGIDHQLVIDADEEV
CCHHHCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHH
FEMNNGCICCTVRGDLIRIIGNLMQRRDRFDHLVIETTGLADPAPVIQSFFVDEVMLRQT
HHCCCCEEEEEECHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHHHHHH
QLDAVVTVVDAKHIWDHWDSSEAQEQIAFADVILLNKQDLVSPEILTALTQRVRSINAIA
HHHHHEEEHHHHHHHHCCCCHHHHHHHHHHHEEEECCHHCCCHHHHHHHHHHHHHHHHEE
TLHPTTHCSVDLTQLLGVQAFNLSHALSIDPEFLDEDAHEHDQTVTSVAITEMGTVDSVK
EECCCCCCCEEHHHHHCCHHCCCCCEEECCHHHHCCCHHHHHHHHHHHHHHHCCCCCHHH
LNRWLYQLVQARGPDLFRMKGILDMDDADRRFVFQGVHMTLDGRPGKPWRPGETRRNELV
HHHHHHHHHHHCCCCEEEECCCCCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCCCCEE
FIGRNLDEAELRNEFLSCLAQPLSPTLTAEVYA
EEECCCCHHHHHHHHHHHHHHCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 1650347 [H]