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The map label for this gene is pkn1 [H]

Identifier: 158334376

GI number: 158334376

Start: 1176040

End: 1176957

Strand: Reverse

Name: pkn1 [H]

Synonym: AM1_1197

Alternate gene names: 158334376

Gene position: 1176957-1176040 (Counterclockwise)

Preceding gene: 158334378

Following gene: 158334375

Centisome position: 18.1

GC content: 50.33

Gene sequence:

>918_bases
GTGATAAAACGTCGTAGATTTATTCAATTTGCTGGACTTGGGAGCATCTCCTTAGCCTGCTCAATACAAGATAAGCTTCA
GATTTCTAAATTTTTTCAATCTCATCCTTTGGCTGAAGTTGATTTACAGACCTTTGAGTATGAGACACCAGAAATTAATA
GAAAGGGGCAGTTAGTTGGCCTTCAAAAGCTAAGTAACCAGTTGTTTTTAGAGCCCTTAGATTCTAAACAAGTATTAAAC
ATGGTAGCCGTCCCATCTAGTCAATCCAGGGTCAGATGGGTTCATTCTAAACATCGCAATTTCGCTCAAGCTCGGCATAC
CAGCGCACCGGCCTTTTTTATTAGTCAATGTCCCATTACCCAAGCCCAATGGGCGGCAGTCGCAGCGTTACCAAAAGTAA
AGCGAGAACTGGATCCTGCCCCCTCCCATTTTCAGGGTTCTCGCCGTCCAGTGGAGAGTATCTCTTGGGTAGAGGCGGTA
GAATTCTGTACTCGCCTCAGCCATCTGACGGGGCGGACCTACCGATTACCCACAGAAGCCCAGTGGGAACAGGCCTGTCG
AGCGGGTAGCCATACCCCGTTCCATACCGGGGCTACCATCACCAGTGAATGGGCCGACTATGTAGGCACTTACACCTTTG
CAGGAGAAGCAGCAGGGACGTATCGGCGACAAACTCTGGATGTAGGGAGCTTTGCCCCGAACGCCTTTGGGTTGCACGAT
ATGCACGGCAATGTGTGGGAATGGTGTGCGGATCGGTGGCAAAGAACCGATGCTCGAAATACCCTGGCACAGCGGTCTAT
TCGGGGTGGGGGCTGGTTAGATCCCCCAGAACGACTGCGCTCGACCAGCCGTTCTGGTTATGATCCCAATGCCCTCAACC
GGACGATTGGATTTCGAGTCATGACGGTATTGAGTTAG

Upstream 100 bases:

>100_bases
TATACCGAACTTTTTTATAGAAATATTTACCTAGTCTATAATTCCATCCTTTGCCAAGACTGCTGATAGGTATTAACTTC
GTGTCTTGAGGTTCAGTTAG

Downstream 100 bases:

>100_bases
GGCAGGAGAACATAATGGCATTGATCCAAAAGATTCCGGTTACCGTTTTGACGGGGTACTTGGGAGCAGGAAAAACCACG
CTACTGAACCGCATTCTGAC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MIKRRRFIQFAGLGSISLACSIQDKLQISKFFQSHPLAEVDLQTFEYETPEINRKGQLVGLQKLSNQLFLEPLDSKQVLN
MVAVPSSQSRVRWVHSKHRNFAQARHTSAPAFFISQCPITQAQWAAVAALPKVKRELDPAPSHFQGSRRPVESISWVEAV
EFCTRLSHLTGRTYRLPTEAQWEQACRAGSHTPFHTGATITSEWADYVGTYTFAGEAAGTYRRQTLDVGSFAPNAFGLHD
MHGNVWEWCADRWQRTDARNTLAQRSIRGGGWLDPPERLRSTSRSGYDPNALNRTIGFRVMTVLS

Sequences:

>Translated_305_residues
MIKRRRFIQFAGLGSISLACSIQDKLQISKFFQSHPLAEVDLQTFEYETPEINRKGQLVGLQKLSNQLFLEPLDSKQVLN
MVAVPSSQSRVRWVHSKHRNFAQARHTSAPAFFISQCPITQAQWAAVAALPKVKRELDPAPSHFQGSRRPVESISWVEAV
EFCTRLSHLTGRTYRLPTEAQWEQACRAGSHTPFHTGATITSEWADYVGTYTFAGEAAGTYRRQTLDVGSFAPNAFGLHD
MHGNVWEWCADRWQRTDARNTLAQRSIRGGGWLDPPERLRSTSRSGYDPNALNRTIGFRVMTVLS
>Mature_305_residues
MIKRRRFIQFAGLGSISLACSIQDKLQISKFFQSHPLAEVDLQTFEYETPEINRKGQLVGLQKLSNQLFLEPLDSKQVLN
MVAVPSSQSRVRWVHSKHRNFAQARHTSAPAFFISQCPITQAQWAAVAALPKVKRELDPAPSHFQGSRRPVESISWVEAV
EFCTRLSHLTGRTYRLPTEAQWEQACRAGSHTPFHTGATITSEWADYVGTYTFAGEAAGTYRRQTLDVGSFAPNAFGLHD
MHGNVWEWCADRWQRTDARNTLAQRSIRGGGWLDPPERLRSTSRSGYDPNALNRTIGFRVMTVLS

Specific function: Together with the serine/threonine kinase pknD, may play a role in the specific interactions with host proteins during intracellular growth [H]

COG id: COG1262

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI257470977, Length=285, Percent_Identity=23.859649122807, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI38202250, Length=296, Percent_Identity=24.3243243243243, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI257470975, Length=170, Percent_Identity=31.7647058823529, Blast_Score=66, Evalue=5e-11,
Organism=Drosophila melanogaster, GI20130397, Length=160, Percent_Identity=33.75, Blast_Score=72, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016187
- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017442
- InterPro:   IPR005532 [H]

Pfam domain/function: PF03781 DUF323; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 34448; Mature: 34448

Theoretical pI: Translated: 10.03; Mature: 10.03

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKRRRFIQFAGLGSISLACSIQDKLQISKFFQSHPLAEVDLQTFEYETPEINRKGQLVG
CCCCHHHHEECCCCCEEEEEEHHHHHHHHHHHHHCCCCEECHHHHCCCCCCCCCCCCEEE
LQKLSNQLFLEPLDSKQVLNMVAVPSSQSRVRWVHSKHRNFAQARHTSAPAFFISQCPIT
HHHHHHHHEECCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCC
QAQWAAVAALPKVKRELDPAPSHFQGSRRPVESISWVEAVEFCTRLSHLTGRTYRLPTEA
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCHH
QWEQACRAGSHTPFHTGATITSEWADYVGTYTFAGEAAGTYRRQTLDVGSFAPNAFGLHD
HHHHHHHCCCCCCCCCCCCHHHHHHHHHHCEEECCCCCCCHHHHEECCCCCCCCCCCCCC
MHGNVWEWCADRWQRTDARNTLAQRSIRGGGWLDPPERLRSTSRSGYDPNALNRTIGFRV
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCCCCHHHHHHHHHEE
MTVLS
EEECC
>Mature Secondary Structure
MIKRRRFIQFAGLGSISLACSIQDKLQISKFFQSHPLAEVDLQTFEYETPEINRKGQLVG
CCCCHHHHEECCCCCEEEEEEHHHHHHHHHHHHHCCCCEECHHHHCCCCCCCCCCCCEEE
LQKLSNQLFLEPLDSKQVLNMVAVPSSQSRVRWVHSKHRNFAQARHTSAPAFFISQCPIT
HHHHHHHHEECCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCC
QAQWAAVAALPKVKRELDPAPSHFQGSRRPVESISWVEAVEFCTRLSHLTGRTYRLPTEA
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCHH
QWEQACRAGSHTPFHTGATITSEWADYVGTYTFAGEAAGTYRRQTLDVGSFAPNAFGLHD
HHHHHHHCCCCCCCCCCCCHHHHHHHHHHCEEECCCCCCCHHHHEECCCCCCCCCCCCCC
MHGNVWEWCADRWQRTDARNTLAQRSIRGGGWLDPPERLRSTSRSGYDPNALNRTIGFRV
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCCCCHHHHHHHHHEE
MTVLS
EEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]